APPLIED CATALYSIS B-ENVIRONMENTAL
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2026
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IF 19.7
Xiao-Hui Wang,Yue-Han Qin,Xue Xiao,Yu Chen,Shu-Ni Li
Histidine-functionalized Cu 2 O effectively stabilizes Cu + species under cathodic conditions. • The histidine functionalization enhances the co-adsorption of *CO and *NO x intermediates. • The formation of an interfacial hydrogen-bond network on the catalyst surface accelerates proton transfer kinetics. • The histidine-functionalized Cu 2 O catalyst achieves a high urea Faradaic efficiency alongside a notably high yield rate. Electrocatalytic C-N coupling for urea synthesis from CO 2 and nitrate (NO 3 - ) offers a sustainable alternative to the energy-intensive industrial process. Copper (Cu)-based catalysts are uniquely capable of activating both CO 2 and NO 3 - ; however, the catalytically active Cu + species is prone to over-reduction to Cu 0 under cathodic conditions, leading to poor selectivity and instability. Herein, we report a histidine-functionalized Cu 2 O nanospheres (His-Cu 2 O NSs) that stabilize Cu + under operating conditions. The preserved Cu + electronic structure promotes synchronized adsorption of *CO and *NO x intermediates, while protonated amino groups construct a hydrogen-bonded interfacial water network that accelerates proton transfer. As a result, the optimized catalyst achieves a urea Faradaic efficiency of 42.3% and a yield rate of 41.9 mmol h −1 g −1 at −1.1 V potential, with exceptional stability over 100 h in both H-type and flow cells. In situ spectroscopy and density functional theory calculations reveal that histidine coordination not only enhances *CO adsorption but also lowers the energy barrier for C-N coupling, thereby accelerating C-N bond formation. Meanwhile, the in-situ EXAFS results indicate that Cu + species can effectively be retained after histidine modification. This work establishes a molecular-level design principle for regulating complex multi-reactant electrocatalysis and provides a versatile strategy for promoting efficient C-N coupling reactions. Download: Download high-res image (156KB) Download: Download full-size image Functionalizing Cu 2 O nanospheres establishes a generalizable stabilization-via-delocalization principle providing a blueprint for designing durable organic-inorganic interfaces for electrocatalytic urea synthesis.
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MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Xin Xin,Qi Zhang,Sujun Yan,Zilong Chen,Xinhai Zhu
Background Monosaccharides and disaccharides are central components of carbohydrate metabolism, and fluctuations in their abundances are closely associated with disease onset, progression, and diagnostic outcomes. However, accurate analysis of trace-level saccharides in complex biological matrices remains challenging due to their limited chromatographic retention, modest ionization efficiency, and limited MS/MS fragmentation. Derivatization has been widely explored to improve analytical performance in LC-MS-based saccharide analysis; nevertheless, further development of simple, sensitive, and broadly applicable strategies is desirable, particularly for small-volume and low-abundance biological samples. This work presents an efficient derivatization-LC-MS approach enabling ultrasensitive quantification of saccharides under microscale analytical conditions. Results A derivatization strategy based on 2-hydrazinyl-6-methoxy-1,3-benzothiazole (HMBT) was developed to enhance LC-MS analysis of monosaccharides and disaccharides. The mild reaction generated stable derivatives directly compatible with LC-MS. HMBT tagging significantly improved chromatographic retention and separation on conventional C18 columns and markedly enhanced ionization efficiency. The derivatives produced high-intensity precursor ions and a dominant, highly responsive product ion, enabling ultrasensitive MRM detection on a triple-quadrupole system. Using nine representative saccharides, the method achieved excellent quantitative linearity down to 10 pg·mL −1 . Application to mouse serum enabled the quantification of glucose at single-cell-equivalent levels, and spiked galactose showed a linear range of 0.05–100 ng·mL −1 . Importantly, the workflow enabled quantification of five endogenous saccharides in individual HeLa cells. Significance The HMBT derivatization workflow provides an ultrahigh-sensitivity LC-MS platform for saccharide analysis, enabling robust MRM-based quantification at pg·mL −1 levels. Its operational simplicity, minimal sample handling, and full compatibility with conventional LC-MS instrumentation facilitate practical implementation. The demonstrated applicability to true single-cell measurements highlights its potential for glycometabolic studies in microscale biological systems.
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C-Journal of Carbon Research
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2025
·Vol. 11
·期 3
·44
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IF 2.9
Youcai Meng,Tianran Wei,Zhiwei Wang,Caiyun Wang,Junyang Ding,Yang Luo,Xijun Liu
Electrocatalytic urea synthesis offers great potential for sustainable strategies through CO2and NO3−reduction reactions. However, the development of high-performance catalysts is often hampered by the complexity of synthetic methodologies and the unresolved nature of C-N coupling pathways. In this study, we present a copper–indium co-doped titanium dioxide (CuIn-TiO2) catalyst that exhibits remarkable efficacy in enhancing the synergistic reduction of CO2and NO3−to produce urea. The bimetallic CuIn site functions as the primary active site for the C-N coupling reaction, achieving a urea yield rate of 411.8 μg h−1mgcat−1with a Faradaic efficiency of 6.7% at −0.8 V versus reversible hydrogen electrode (vs. RHE). A body of experimental and theoretical research has demonstrated that the nanoscale particles enhance the density of active sites and improve the feasibility of reactions on the surface of TiO2. The co-doping of Cu and In has been shown to significantly enhance electronic conductivity, increase the adsorption affinity for *CO2and *NO3−, and promote the C-N coupling process. The CuIn-TiO2catalyst has been demonstrated to effectively promote the reduction of NO3−and CO2, as well as accelerate the C-N coupling reaction. This effect is a result of a synergistic interaction among the catalyst’s components.
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Journal of Materials Chemistry A
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2026
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IF 9.2
Liming Xiao,Fangyuan Yu,Ping Sun,Xiaodong Wang,Linmao Wen,Yunzi Ren,Feng Cao,Jun Mao,Qian Zhang
With the rapid development of the Internet of Things (IoT), there has been a significant surge in demand for flexible power supply. However, most existing solutions still face challenges in delivering both a continuous, stable energy supply and excellent mechanical adaptability.Herein, we report a Ag2Se network fabricated via a single-step electrodeposition process, which enables continuous regulation of porosity in the range of 75%-99%. This method leads to the formation of a highly interconnected porous architecture. The optimized network with 92% porosity demonstrates a synergistic enhancement of thermoelectric and mechanical properties, achieving a zT value of 0.38 and excellent strain stability, with only a 6.4% increase in resistance after 1000 compressive cycles. The single-leg device based on this material delivers a high power density of 181.5 μW cm -2 under a temperature difference of 40 K. In comparison, a denser network with 86% porosity, while mechanically rigid, achieves a room-temperature zT of 1.0, outperforming most bulk Ag2Se thermoelectric materials. This work provides an effective strategy to coordinate thermoelectric performance and mechanical flexibility through structural porosity modulation, paving the way for advanced wearable self-powered technologies.
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EUROPEAN POLYMER JOURNAL
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2022
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IF 5.546
Zhihua Shen,Jialiang Chen,Gefei Li,Gaohua Situ,Xiaofeng Ma,Ye Sha,Dong Zhao,Qun Gu,Meng Zhang,Yanlong Luo,Zhenyang Luo
It has been a challenge to impart high strength and toughness to room-temperature self-repairing polyurethane/polyurea materials. We report a room-temperature self-repairing thermoplastic polyurea elastomer (PU) with mechanical robustness. When thiosemicarbazide was used as a chain extender, strong (or weak) hydrogen bonds were formed between C O (or C S) and N H groups in the hard regions of PU. The results were optimized mechanical and self-repairing properties: the tensile strength, elongation at break, toughness, and self-repairing efficiency of the PU reached 4.43 MPa, 1498.37%, 55.14 MJ m −3 , and 96.3%, respectively. We found that the increase of hard segments led to increased/decreased number of ordered/disordered hydrogen bonds, as well as enhancement of both the aggregation of hard segments and the degree of microphase separation. We proposed a model dealing with the relation between the hard segment content and the hydrogen-bonding arrays and explored the exchange rate and the order–disorder transition of hydrogen bonds, to provide an insight into the optimization of mechanical and self-repairing properties.
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ACS Nano
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2023
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IF 17.1
Xianyong Zhou,Xiangfeng Luan,Luozheng Zhang,Hang Hu,Zhengyan Jiang,Yaru Li,Jiawen Wu,Yanliang Liu,Jiabang Chen,Deng Wang,Chang Liu,Shi Chen,Yong Zhang,Meiqing Zhang,Yuanjun Peng,Pavel A. Troshin,Xingzhu Wang,Yiyong Mai,Baomin Xu
The crystalline morphology of perovskite film plays a key role in determining the stability and performance of perovskite solar cells (PSCs). In addition, the work function and conductivity of hole transport layer (HTL) have a great influence on the effciency of PSCs. Here, we develop a synergistic doping strategy to fabricate high-performance inverted PSCs, doping a functional nanographene (C78-AHM) into the poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine (PTAA) HTL, thus forming an HTL with higher conductivity, lower roughness, and frontier energy levels matching the perovskite absorber work function. On this basis, thiosemicarbazide (TSC) was doped into the precursor solution of perovskite as the grain and interface modifier to further improve the crystalline morphology of perovskite film. Compared with the current single passivation method, this codoping strategy can simultaneously reduce the surface and bulk defects of perovskite film and reduce the interface energy barrier. Eventually, high-quality TSC-doped perovskite films based on C78-AHM-doped PTAA HTL are obtained with over 2 μm sized grains, pinhole-free, and improved crystallinity. As a result, this synergistic doping strategy increases the efficiency of the device from 20.27% to 23.28%. Furthermore, the environmental and thermal stabilities of the devices are significantly improved. Therefore, this work provides a simple way for the preparation of other efficient optoelectronic devices.
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CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Yanmei Huang,Yuting Wang,Yang Liu,Aijing Ma,Jianzhou Gui,Chaoxin Zhang,Yifu Yu,Bin Zhang
Electrochemical synthesis of urea from carbon dioxide and nitrogenous species is a promising sustainable strategy, which can be easily incorporated into distributed renewable energy systems. However, a low concentration of urea produced in a complex solution environment brings challenges to its accurate quantification. Here an overall comparison (e.g., accuracy, reliability, anti-interference ability) of the frequently-used determination methods is provided after considering the potential interference factors. Besides, a rigorous urea detection flowchart and a recommended standard are established to achieve a more accurate and responsible performance evaluation in electrocatalytic urea production. This work guides the reliable quantification in urea synthesis, especially at a low concentration within a complicated electrocatalytic system.
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Journal of Fungi
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2022
·Vol. 8
·期 8
·762
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IF 5.724
Xinying Duan,Li Zhang,Hongyan Si,Jie Song,Peng Wang,Shangxing Chen,Hai Luo,Xiaoping Rao,Zongde Wang,Shengliang Liao
Control of fungal phytopathogens affecting crops and woodlands is an important goal in environmental management and the maintenance of food security. This work describes the synthesis of 37 camphor derivatives, of which 27 were new compounds. Their antifungal effects on six fungi were evaluated in vitro. Compounds3a,4aand5kshowed strong antifungal activity againstTrametes versicolor, with EC50values of 0.43, 6.80 and 4.86 mg/L, respectively, which were better than that of tricyclazole (EC50118.20 mg/L) and close to or better than that of carbendazim (EC501.20 mg/L). The most potent compound,3a, exhibited broad-spectrum antifungal activity towards six fungi with EC50values within the range of 0.43–40.18 mg/L. Scanning electron microscopy demonstrated that compounds3a,4aand5kgave irregular growth and shriveling of the mycelia. In vitro cytotoxicity evaluation revealed that the tested camphor derivatives had mild or no cytotoxicity for LO2and HEK293T cell lines. Quantitative structure−activity relationship (QSAR) analysis revealed that the number of F atoms, relative molecular weight, the atomic orbital electronic population and total charge on the positively charged surfaces of the molecules of camphor derivatives have effects on antifungal activity. The present study may provide a theoretical basis for a high-value use of camphor and could be helpful for the development of novel potential antifungals.Keywords:camphor;synthesis;antifungal activity;cytotoxicity;QSAR
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2022
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IF 24.319
Chunfeng Shao,Lingmin Wu,Yinghua Wang,Konggang Qu,Hailiang Chu,Lixian Sun,Jianshan Ye,Baitao Li,Xiujun Wang
Single-atom Fe catalysts are a promising substitute to Pt catalysts for oxygen reduction reaction (ORR). Adjusting metal energy level through direct atomic interface regulation can effectively improve catalytic performance but still in its infancy. Herein, highly active nitrogen and sulfur dual-coordinated asymmetric Fe center anchored in carbon nanoparticles were developed. Spontaneously absorbed OH ligand is steadily anchored in asymmetric atomic interface, constructing new FeN 3 S-OH moiety. Theoretical calculations reveal that the incorporated S atom combined with OH ligand as energy level modifier effectively activate Fe center by electronic modulation and d -band center shift, rendering improved ORR activity of FeNSC-2Fe with E 1/2 of 0.913 V in alkaline, 0.806 V in acidic and 0.711 V in neutral media. The FeNSC-2Fe-based device displays high power density of 306 mW cm −2 in Zn-air battery and 2485 mW m −2 in microbial fuel cell . This work provides a new perspective for the controllable synthesis and performance optimization for electrocatalysts.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2021
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IF 8.128
Feifei Xu,Jianghong Zhao,Jianlong Wang,Taotao Guan,Kaixi Li
High activity trifunctional non-noble electrocatalysts , targeting oxygen reduction reaction (ORR), hydrogen evolution reaction (HER), and oxygen evolution reaction (OER), are rationally designed by integrating the merits of both Co 9 S 8 nanoparticles and carbons nanosheets . Herein, Co 9 S 8 loaded with S, N co-doped carbon core–shell catalyst (Co 9 S 8 @SNC) was reasonably designed and synthesized by using the strong coordination effect between Co 2+ and C S at the molecular level. The significant synergistic effect between the S, N co-doped carbon shell and Co 9 S 8 core endows the catalyst with excellent catalytic performance for ORR, HER, and OER reactions. The carbon shell enhances the conductivity of the hybrid material , while the Co 9 S 8 core provides the main catalytic active sites. More specifically, the half-wave potential for ORR is 0.846 mV, and the overpotential at 10 mA cm −2 for OER and HER are 320 mV and 170 mV, respectively. To test its practical application, zinc-air battery assembled by Co 9 S 8 @SNC shows a high power density of 239 mW cm −2 , excellent rechargeability, and long cyclic stability. This work provides a promising and extensible method to in-situ synthesize core–shell metal sulfides loaded S, N co-doped carbon composites, which can be a promising candidate for electrocatalytic material in energy storage and conversion devices.
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FOOD CHEMISTRY
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2021
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IF 7.514
Pei Jia,Jiayu Yang,Jinjie Hou,Kairong Yang,Taotao Zhe,Tong Bu,Li Wang
A new ratiometric platform was developed for sensing Hg 2+ , which combined fluorescence and scattering simultaneously. This ratiometric strategy reflected superiorities over conventional methods, since the two independent signals at irrelevant categories meet the requirements of sufficient wavelength separation, stimulation under one excitation, and collection on single instrument. Herein, nonconjugated polymer dots ( N -PDs) were served as the recognition unit for Hg 2+ with turn-off fluorescence and turn-on scattering. Additionally, two signal collection tactics were proposed to achieve fluorescence and scattering in a window: one was to record down-conversion fluorescence and second-order scattering spectra (FL@SOS), and the other was to gather the fluorescence excited by second-order diffraction light and first-order scattering (SODL-FL@FOS). This ratiometric sensor exhibited outstanding performance toward Hg 2+ in the range of 0.1–50 μM with the detection limit of 27 nM. By contrast, the present proposal provided a more ingenious and scalable way to construct ratiometric sensor than traditional approach.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2021
·Vol. 138
·期 42
·51226
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IF 3.125
Yifan Liu,Ruihan Pei,Yuancai Lv,Chunxiang Lin,Jianhui Huang,Minghua Liu
Due to the low concentration of silver in water, most of the cellulose adsorbents exhibited low removal efficiency, which greatly limited their practical applications. Herein, a cellulose aerogel modified by thiosemicarbamide (CAT) was fabricated for reducing and adsorbing silver ions from low concentration wastewater. The characterization results concluded that CAT owned a three-dimensional spongy structure with many circular microspheres and a better specific surface area (19.37 m 2 g −1 ), as well as the functional groups of ─C═N + ─H and ─(C═S)─N. The static batch adsorption experiments demonstrated that CAT could reached the maximum removal percentage of 94.94% and adsorption capacity of 42.12 mg g −1 under the initial concentration of Ag(I) was 15 mg L −1 and the pH value was 7. Meanwhile, the adsorption of Ag(I) on CAT was second-order reaction, and the Langmuir model could better fit the adsorption process. In addition, CAT exhibited wide pH values (1–9) adaptability and excellent adsorption performance for silver through electrostatic interaction, chelation, and reduction. This study probably provides a new method as well as important experimental data and theoretical reference for the removal of silver ions and other metals.
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