Translational Research
·
2024
·
IF 6.4
Aoran Huang,Jianyun Rao,Xin Feng,Xingru Li,Tianhua Xu,Li Yao
Vascular calcification (VC) poses significant challenges in cardiovascular health. This study employs single-cell transcriptome sequencing to dissect cellular dynamics in this process. We identify distinct cell subgroups, notably in vascular smooth muscle cells (VSMCs), and observe differences between calcified atherosclerotic cores and adjacent regions. Further exploration reveals ID3 as a key gene regulating VSMC function. In vitro experiments demonstrate ID3′s interaction with USP1 and E12, modulating cell proliferation and osteogenic differentiation. Animal models confirm the critical role of the USP1/ID3/E12/P21 axis in VC. This study sheds light on a novel regulatory mechanism, offering potential therapeutic targets. 1. This study uses single-cell transcriptome to investigate vascular calcification in depth. 2. This study successfully identifies cellular heterogeneity related to vascular calcification. 3. This study reveals the crucial role of ID3 in vascular smooth muscle cell osteogenic differentiation. 4. In vivo and in vitro experiments of this study demonstrate the regulatory role of the USP1/ID3/E12/P21 axis in calcification. 5. This study provides potential molecular targets for the treatment of calcification-related diseases.
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Journal of the Taiwan Institute of Chemical Engineers
·
2025
·
IF 6.3
Bing Liao,Ziyi Wang,Ruyi Chang,Zhengchun Hu,Qiuyue Ye,Wen Xu,Jiale Wu,Zhuoyuan Zhou,Wu Shen,Na Guo,Lingfeng Huang,Zhicheng Pan
Background Sulfate radical−based advanced oxidation processes (SR-AOPs) show promising prospects for the pretreatment and advanced treatment of ammonia nitrogen in landfill leachate. However, in high chloride ion environments, SR-AOPs often lack selectivity, leading to the over-oxidation of ammonia nitrogen to undesirable nitrate NO 3 − and NO 2 − rather than the desired N 2 , which remains a major challenge. Methods In this study, CoFe 2 O 4 was prepared by a gel-calcination method and the effects of chloride ions (Cl − ) and other parameters on the performance of CoFe 2 O 4 -activated peroxymonosulfate (PMS) oxidation system for the removal of ammonia nitrogen and the selectivity of oxidation products were systematically investigated. Significant findings Cl − played a crucial role in determining the ammonia removal efficiency and nitrogen selectivity. Under the optimum conditions of 30 mM of PMS, 0.1 g/L of catalyst and 20 mM of Cl − , the ammonia removal efficiency of the system was nearly 100 %, and the nitrogen selectivity reached 88.1 %. The main species in the activation process of the PMS was Co(II)-OH, and the formation of this complex was promoted by Fe(III). SO 4 · − , HO · , and chlorine species (Cl · , ClO · , and HClO) were generated in the system. Among them, SO 4 · − and HO · indirectly contributed to ammonia oxidation by reacting with Cl − to produce reactive chlorine species, which subsequently oxidized ammonia nitrogen.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2026
·
IF 9.1
Zhipeng Liu,Beizhao Chen,Caihong Liu,Youmei Xu,Weiwen Chen,Chaoqun Zhu,Yufei Shu,Shidong Zheng,Fan Wang,Yunjiao Han,Mengxia Wang,Yihan Xue,Zhongying Wang
Chlorinated antibiotics are persistent halogenated pollutants whose detoxification requires deep dechlorination rather than simple parent-compound removal. Here, we report a structurally engineered, earth-abundant copper electrode (Tre-Cu) that enables rapid and deep electrochemical hydrodechlorination of chlorinated antibiotics. Prepared through a facile sequence of oxidation, in situ complex dissolution, and chloride-assisted electroreduction, Tre-Cu undergoes spontaneous surface reconstruction during operation, evolving into a spindle-shaped, sharp-tipped architecture. This electrode achieved nearly complete florfenicol removal within 20 min and full stoichiometric chloride release within 30 min under ambient air, while maintaining stable performance over 10 cycles and 36 h long-term continuous operation, as well as robust tolerance in environmental water matrices. Mechanistic studies show that dechlorination on Tre-Cu is dominated by direct electron transfer rather than atomic hydrogen-mediated reduction. Time-resolved SEM and XPS reveal that transient CuCl-like surface species drive the formation of the activated tip-rich morphology. Finite element simulations, electrochemical analysis, and DFT calculations further demonstrate that the reconstructed surface strengthens the local electric field, enriches interfacial K + , enhances pollutant adsorption, and lowers the barriers for sequential C-Cl bond cleavage. This work offers a simple strategy to couple surface reconstruction with interfacial microenvironment engineering for deep electrochemical detoxification.
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Catalysts
·
2026
·Vol. 16
·期 7
·620
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IF 4.5
Li Fang,Yuxian Jiang,Xueyang Jiang,Qin Zhang,Sihui Suo,Chenhui Zhao,Jiayu Song,Jiancong Liu
Oxygen vacancies are a key factor determining the efficiency of the CO2hydrogenation reaction and play a crucial role in CO2adsorption and activation. However, effectively regulating the concentration of oxygen vacancies to enhance the performance of the light-driven reverse water gas shift (RWGS) reaction remains a challenge. To address this, this study successfully developed Pt/TiO2catalysts with varying oxygen vacancy concentrations by controlling the morphology of TiO2. Structural characterization results indicate that, compared to Pt/TiO2-NR, Pt/TiO2-NB exhibits a higher oxygen vacancy (OV) concentration and greater CO2absorption. Catalytic performance evaluation results showed that under an irradiance of 2.5 W/cm2, the CO production rates of the Pt/TiO2-NB catalyst reached 57.03 mol·gPt−1·h−1. Furthermore, the catalyst maintained excellent catalytic stability during 45 h of continuous operation, demonstrating good potential for practical applications.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·123929
·
IF 7.5
Geng Huang,Linfeng He,Haiwen Ding,Minfeng Wang,Lukai Zhuang,Zhongmin Fang,Guoqing Huang,Xiaodan Zhao,Jing Zou
Ammonium nitrogen (NH 4 + −N) pollution represents a considerable risk to both aquatic ecosystems and public health, necessitating efficient and sustainable treatment methods. In this study, bromide ion (Br − ) commonly present in wastewater was employed as an activator for peroxymonosulfate (PMS) to markedly enhance NH 4 + –N removal. NH 4 + –N elimination by Br − /PMS system followed the pseudo -zero-order kinetics, and the observed rate constant reached 0.52 mg L −1 min −1 in the presence of 825 μM Br − at pH 8.0. Quenching experiments demonstrated that primary reactive species for NH 4 + −N removal in Br − /PMS system was hypobromous acid (HBrO), rather than Br • , Br 2 •− , 1 O 2 , • OH and SO 4 •− . HBrO was primarily generated through the direct reaction of PMS and Br − . Notably, the primary product of NH 4 + –N elimination was the environmentally friendly gas N 2 (about 86%) in Br − /PMS system. Increasing Br − and PMS concentrations was advantageous for increasing NH 4 + –N elimination rate. Common anions in water (e.g., SO 4 2− , NO 3 − , and PO 4 3− ) and natural organic matter (e.g., humic acid) exhibited negligible effects on removing NH 4 + –N in Br − /PMS system, while Cl − promoted NH 4 + –N elimination. Furthermore, Br − /PMS system demonstrated exceptional performance in removing NH 4 + –N from actual aquaculture wastewater samples. To conclude, this study presented an efficient strategy to enhance the oxidative ability of PMS for NH 4 + –N elimination and highlighted its potential application in treating bromine-containing wastewater.
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iScience
·
2026
·Vol. 29
·期 7
·
IF 4.5
Yan Chen,Yuxin Cai,Yuhan Zhang,Siyi Li,Siyun Long,Xiaoqin Xiong,Min Liu,Junyan Chen,Shizhuo Ma,Liyuan Zhang,Zuoliang Sun
Escalating phosphorus (P) pollution and resource scarcity underscore the urgent need for sustainable wastewater treatment and nutrient recovery systems. However, systematic research on P-removal efficiency and its recovery across concentrations under mixotrophic conditions is still lacking. In this study, Spirodela polyrhiza was used to investigate the physiological responses to P-containing simulated wastewater with respect to its efficacy for pollutant removal and the potential for simultaneous biomass recovery. Our results indicate that S. polyrhiza achieved a maximum total P-removal efficiency of 93.78% at 17 mg/L P, while exhibiting high adaptive plasticity. Under P deficiency, carbon was preferentially allocated to starch accumulation (up to 214 mg/g DW), while elevated P levels stimulated protein and lipid synthesis. The biomass was also enriched with essential minerals, including P, K, Mg, and Zn, supporting its potential use as animal feed, biofuel feedstock, or biofertilizer. This synergistic approach offers a practical pathway to advance the circular bioeconomy and address pressing environmental challenges related to nutrient pollution and resource scarcity.
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JOURNAL OF MATERIALS SCIENCE
·
2026
·Vol. 61
·期 37
·27895-27908
·
IF 4.4
Li Jing,Wang Jin
CO is a key product of CO 2 electroreduction (CO 2 ER) and an important feedstock for the production of hydrocarbons and alcohols. Herein, we synthesized electrocatalysts by growing Cu nanocluster on manganese oxide (Cu n -Mn 3 O 4 ) for CO 2 ER. In 0.5 M KHCO 3 electrolyte using an H-cell, the optimized Cu 0.4 -Mn 3 O 4 achieved a Faradaic efficiency for CO (FE CO ) of 88.5 ± 2.3% and a current density of 14.3 ± 0.2 mA cm −2 at − 0.6 V vs. RHE, while substantially suppressing the hydrogen evolution reaction (HER). The better performance was due to the electrons transferred from Mn to CO 2 by Cu as a shuttle and anchored Cu nanoclusters shifted the d-band center toward the Fermi level, which was more conducive to the intermediate formation. In situ electrochemical attenuated total internal reflectance (EC-ATR) spectroscopy and density functional theory (DFT) calculations revealed the *COOH intermediate (1399 cm⁻ 1 ) along the CO 2 → *COOH → *CO → CO pathway. Moreover, the DFT calculations further demonstrated the Gibbs free energy barrier (ΔG) of the key steps in the CO 2 ER pathway and the corresponding intermediate configurations, which were used to reveal the relationship between the catalyst structure and CO 2 ER performance. The design of the metal/metal oxide electrocatalyst in this study provides a new perspective for the highly selective reduction of CO 2 to CO. Graphical
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Communications Earth & Environment
·
2026
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IF 9.3
Yang Ning,Wang Xiaofei,Wang Junfeng,Deng Junjun,Wei Zhenwei,Fu Pingqing
The high electric field at the microdroplet interface plays a crucial role in regulating aqueous aerosol chemistry. However, the impact of charge at the air-water interface on sulfur-containing aerosols remains unclear. Here we show, using various microdroplet systems, how interfacial reactions of sulfur-containing aerosols proceed under different charge conditions. Field observations were also conducted across multiple regions to characterize the molecular composition of aqueous sulfur-containing aerosols. In small negatively charged droplets, sulfite is spontaneously oxidized to sulfate, with an estimated rate comparable to reported rates of sulfite oxidation by common atmospheric oxidants. Meanwhile, sulfur radicals like sulfate radicals are generated, leading to the rapid formation of organosulfates. In large positively charged droplets, sulfate is spontaneously reduced to sulfite radicals and sulfite, promoting the formation of organosulfonates. These results provide key insights into how charge at the air–water interface affects sulfur aerosols and contribute to our understanding of air pollution.
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RSC Advances
·
2026
·Vol. 16
·期 11
·10243-10254
·
IF 6.1
Wenhao Liu,Yanfeng Zhu,Zhihao Liu,Jianxia Gou
Marine corrosion poses a critical threat to the safety of offshore oil and gas facilities. To address the intrinsic drawbacks of pristine TiO2, ZnS/CdS/Ti3+-TiO2 nanotube composites were rationally fabricated via a synergistic strategy combining electrochemical anodization and successive ionic layer adsorption and reaction (SILAR) techniques. Structural and optical characterization confirmed that the as-synthesized composites feature a well-constructed cascade band alignment, which efficiently mitigates the recombination of photogenerated electron–hole pairs. Accordingly, the optimized photoanode delivered a high photocurrent density of 279 µA cm−2. When coupled with 316 stainless steel (316 SS), the composite exhibited a pronounced photo-induced potential of −0.89 V (vs. SCE), achieving a remarkable performance enhancement over pristine TiO2. This enhanced photocathodic protection originates from the synergistic interplay between Ti3+ self-doping and the ZnS/CdS heterojunction: Ti3+ self-doping introduces abundant electron donors to enhance the electrical conductivity of the composite, whereas the ZnS/CdS heterojunction broadens the visible-light absorption range and accelerates the separation and directional migration of photogenerated charge carriers.
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ACS Sustainable Chemistry & Engineering
·
2026
·
IF 7.6
Muze Han,Jiayi Li,Jinjing Liu,Ronghua Yu,Yifu Zhu,Yujie Huang,Kunkun Tu,Shihang Li
Dust pollution threatens ecological stability and human health, but conventional suppressants suffer from short durability, high water demand, and toxicity. This study developed a bio-inspired bacterial/sodium alginate (SA) hydrogel (BSH) dust suppressant composed of Bacillus mucilaginosus (B.m), SA, and NaHCO3. Its application uses a two-step process: first spraying BSH for physical dust adhesion and then CaCl2 to supply Ca2+ ions. Carbonic anhydrase secreted by B.m catalyzes the hydration of ambient CO2 into CO32–, which reacts with Ca2+ to form CaCO3; NaHCO3 further enhances CO32– availability, promoting stable calcite and dust matrix consolidation. The BSH exhibits favorable interfacial properties: a low surface tension of 31 mN/m and strong wettability, with a contact angle of 60°. The hydrogel suppressant achieves a dust suppression efficiency of up to 99.76%, outperforming conventional formulations, and maintains >95% efficiency over a 7 day wind erosion trial, alongside superior water retention. This scalable, biodegradable hydrogel enables long-term dust mitigation and synergizes with greenhouse gas sequestration, shifting the paradigm from passive dust control to climate-friendly environmental management.
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Research
·
2026
·
IF 12.9
Wenchong Ouyang,Lin Mei,Limin Xu,Chengwei Zhao,Yu Bai,Ziyang Zhao,Rongxin Tang,Tianzhi Luo,Zhengwei Wu
Stretchable conductive hydrogel composites with infrared stealth and electromagnetic interference (EMI) shielding are in high demand for aerospace, military, and soft robotics. However, realizing stable and efficient performance with low conductive filler content under harsh conditions remains a substantial challenge. Herein, a flexible multifunctional double network hydrogels with high performance and environmental stability was constructed via transition metal carbide/nitride (MXene)/(NH 4 ) 2 SO 4 -treated strategy-assisted ultrasonic dispersion and thermal polymerization method. The synergistic effect of MXene and (NH 4 ) 2 SO 4 within the hydrogel system led to a 3-fold enhancement in mechanical properties, 20-dB improvement in EMI shielding effectiveness, and 40% enhancement in the gauge factor with only 0.12 wt % conductive filler. Benefiting from its high conductivity, efficient thermal insulation, and composite network structure, the double network hydrogels maintain stable EMI shielding and infrared stealth performance under various harsh conditions including repeated stretching, prolonged water evaporation, low-temperature freezing, high-temperature heating, alcohol lamp flame exposure, and high-strain stretching. These findings demonstrate that the hydrogels combine ultra-low filler efficiency, environmental robustness, and multifunctional adaptability, making it a promising candidate for next-generation aerospace, military, and wearable electronic applications.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Dongdong Chen,Siting Hu,Zhenzhen Jia,Huibin Liu,Bo Zhang,Shasha Liu,Wuwan Xiong,Xiang Li
The integration of lubricant oil additives or biofuels compels the Passive NO x Adsorber (PNA) within automotive exhaust after-treatment systems to withstand chemical poisoning from contaminants such as phosphorus (P). For the first time, lanthanum (La) has been employed to enhance the operational efficacy of Pd-loaded small-pore SSZ-13 zeolite (i.e., Pd-SSZ-13) in the presence of phosphorus species. Our findings reveal that La modification significantly bolsters the resilience of Pd-SSZ-13 against P-induced deactivation during the cold-start phase. Furthermore, we have elucidated a pronounced reduction in the degradation of active cationic Pd 2 + ions and Brønsted acid sites within the Pd-SSZ-13 framework upon the introduction of La. Notably, La not only exerts a stabilizing influence on the framework aluminum at the Brønsted acid sites but also effectively mitigates the interaction between the active Pd 2+ species and phosphorus, thereby preventing the formation of metaphosphate and its subsequent conversion into bulk PdO x aggregates. This research offers profound insights, particularly concerning the utilization of La to augment the resistance of Pd-SSZ-13 zeolite catalysts against poisoning by various chemical poisons (such as alkali metals or sulfur) and to enhance their high-temperature hydrothermal stability.
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