JOURNAL OF CHEMICAL THERMODYNAMICS
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2023
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IF 2.6
Wenyang Fan,Chunliang Ge,Delong Ding,Liping Deng,Jun Gao,Dongmei Xu
Separation of sulfides from fuel oil is of great significance for environmental protection. In this paper, the organic solvent (sulfolane) was selected to separate sulfides (thiophene and 2-methylthiophene) from model fuel oil ( n -heptane). The liquid–liquid equilibrium data of the mixtures ( n -heptane + thiophene/2-methylthiophene + sulfolane) were measured at 303.15, 313.15 and 323.15 K under 101.3 kPa. The mass conservation of the experimental data were checked, and the reliability of the tie-lie data were evaluated by the Bachman, Hand and Othmer-Tobias equations. The extraction performance of sulfolane was assessed through the separation factor and partition coefficient, and compared with those for other reported solvents, indicating that sulfolane has better extraction performance for thiophene compared with 2-methylthiophene. Then, the quantum chemical calculation was applied to found the separation mechanism of sulfolane. The analysis of electrostatic potential, interaction energies, and reduced density gradient showed that the main interactions between sulfolane and thiophene (or 2-methylthiophene) were van der Waals and weak hydrogen bond forces. Finally, the non-random two-liquid theory (NRTL) and universal quasi-chemical theory (UNIQUAC) models were applied to fit the tie-line data of the investigated mixtures with the root-mean-square deviation (RMSD) lower than 0.01. The mixed surface analysis method based on Gibbs energy topology is used to verify the binary interaction parameters, which provides basic data for simulating the separation process of sulfide in fuel oil.
研究领域:
环境科学
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化学工程
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DOI
高影响因子
Journal of Materials Chemistry B
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2017
·Vol. 5
·期 22
·4121-4127
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IF 4.543
Hansen Yu,Yanan Wang,Haiyang Yang,Kang Peng,Xingyuan Zhang
Injectable self-healing hydrogels have found broad applications in drug delivery, tissue engineering and controlled 3D cell culture. Recently, cyclic disulfides were found to be useful in cross-linking and stabilizing liposomes by disulfide exchange polymerization, benefiting from the enhanced reactivity of the disulfide bonds. Herein, we report an injectable self-healing hydrogel constructed from cross-linked F127 with thermo and pH dual responsivity. The rapid sol–gel transition ability at body temperature allows it to be used as an injectable hydrogel. And the increased reactivity of the disulfides of cyclic dithiolane due to the ring tension makes the hydrogel self-heal under not only alkaline conditions but also neutral or even mildly acidic conditions.
研究领域:
材料科学
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生物材料
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药物递送
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组织工程
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DOI
PubMed
高影响因子
APPLIED ENERGY
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2018
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IF 7.9
Lidong Wang,Songhua Yu,Qiangwei Li,Yifeng Zhang,Shanlong An,Shihan Zhang
The phase splitting solvent as a promising alternative to MEA for CO 2 capture has received an increasing attention due to its low energy consumption. In this paper, the mixture of diethylenetriamine (DETA) and sulfolane was employed to absorb CO 2 from the simulated flue gas . Its phase splitting behavior was investigated. The species in each separated phase were identified using nuclear magnetic resonance (NMR), revealing that the upper layer was a CO 2 -rich phase and mainly consisted of DETA and DETA-carbamate. Whereas, the lower layer was CO 2 -lean phase with the sulfolane presented individually. The CO 2 absorption kinetics was also measured in a wetted-wall column as a function of temperatures, CO 2 loadings, and gas flow rate . Their impacts on the enhancement factor and mass transfer resistance were calculated by the Vapor-Liquid Equilibria (VLE) model, implying that the main CO 2 mass transfer resistance gradually transferred from the gas side to the liquid side with the CO 2 loading increasing from 0 to 2.21 mol L −1 . During the CO 2 absorption process, sulfolane acted as an inert solvent for substituting the role of water and separated from the absorption product. Consequently, the sensible heat and vaporization heat were substantially decreased by 59% and 12%, respectively. Hence the total heat duty was lowered by 19% which might noticeably advance the CO 2 capture technology.
研究领域:
化学工程
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环境科学
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DOI
高影响因子
Journal of Environmental Chemical Engineering
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2023
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IF 7.7
Zhongmou Liu,Pan Zhang,Xiangyu Zhao
Reduced graphene oxide supported with ferric ion (Fe(III)-rGO) was successfully prepared, and performed as an excellent catalyst to activate hydrogen peroxide (H 2 O 2 ) and peroxymonosulfate (PMS) for isoprothiolane (IPT) degradation. IPT removal efficiency was proven to be better in the Fe(III)-rGO/H 2 O 2 /PMS system (96.2%) than in the Fenton-like reaction (72.6%) and PMS-AOP (80.0%) individually. X-ray photoelectron spectroscopy showed that Fe(III) was reduced in Fenton-like reaction, and the reduced Fe(II) played a crucial role in the subsequent PMS-AOP. The combination of the Fenton-like reaction and PMS-AOP involved the valence state conversion of Fe, which consequently improved Fe(III)-rGO utilization rate and IPT removal efficiency. Fe(III)-rGO remarkably boosted the Fe(III)/Fe(II) cycle and generated superoxide radical (O 2 − •) and singlet oxygen ( 1 O 2 ) in the Fe(III)-rGO/H 2 O 2 /PMS system. Fe(III)-rGO acts as the electron transfer mediator; thus, promoting electron transfer from IPT to H 2 O 2 and PMS and accelerating the generation of active species. Fe(IV) with high oxidation performance was formed in PMS-AOP and efficiently removed some of the IPT. IPT removal efficiency was more than 90% at a pH range of 3–11; this efficiency could be maintained above 50% even after five consecutive degradation experiments, exhibiting excellent stability and reusability of Fe(III)-rGO. Additionally, iron sludge formation was greatly reduced because of the stable chemical bonding of iron ions to the rGO surface. Therefore, this study provides a new multisystem and synergistic approach for the efficient removal of organic micro-pollutants from water.
研究领域:
环境科学
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化学工程
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DOI
高影响因子
Journal of Pharmaceutical Investigation
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2025
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IF 5.1
Yuan Haimeng,Chen Yao,Hu Yuting,Li Yanxin,Zhang Hongyuan,Zhang Shenwu,Chen Qin,Zhou Wenhu,Sun Jin,He Zhonggui,Wang Yuequan,Luo Cong
Purpose Chemotherapy remains a key treatment option for cancer therapy. Epirubicin (EPI) is an important antitumor agent. However, the short half-life and pronounced toxic side effects have resulted in suboptimal clinical outcomes. To overcome these challenges, we employed a prodrug strategy combined with bio-nanotechnology to achieve effective treatment with satisfactory safety. In addition, we investigated how the position of disulfide bond affects drug release, pharmacokinetics, and antitumor efficacy of EPI, while also analyzing the underlying mechanisms. Methods We designed and synthesized three lipophilic EPI-C 18 prodrugs (α-ESC, β-ESC, γ-ESC), which were then formulated into carrier-free nanoassemblies (α-ESC NAs, β-ESC NAs, γ-ESC NAs). In vitro studies were conducted to evaluate the stability and drug release of these nanoassemblies, followed by in vivo pharmacokinetic and antitumor efficacy assessments, providing valuable insights into their therapeutic potential. Results The placement of the disulfide bond plays a critical role in influencing the stability, drug release, cytotoxicity, pharmacokinetics, and antitumor effectiveness of the nanoassemblies. Specifically, β-ESC NAs displayed the strongest antitumor activity. Conclusion By constructing reduction-responsive EPI prodrug nanoassemblies, we achieved a highly effective and low-toxicity therapeutic outcome. β-ESC NAs proved to be the most optimal EPI prodrug nanoassembly. This study provides a promising avenue for the clinical use of chemotherapy agents.
研究领域:
药理学
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肿瘤学
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生物化学
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DOI
高影响因子
JOURNAL OF THE ENERGY INSTITUTE
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2020
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IF 4.748
Chao Liu,Min Wei,Fei Wang,Linshan Wei,Xiaoyan Yin,Jianchun Jiang,Kui Wang
Thermochemical conversion of lignocellulosic biomass into value-added chemicals has attracted great interest worldwide. Herein, we report an effective and facile process to transform bamboo into 5-hydroxymethylfurfural (5-HMF), furfural (FF) and levulinic acid (LA) using metal chlorides as catalysts. The effects of the reaction parameters, such as the reaction time, temperature, initial pressure and catalyst loading on the bamboo conversion and product yields were investigated. Notably, the optimum reaction conditions were heating 200 °C for 2 h using 0.75 g of SnCl 4 as catalyst in a 90.0 wt% aqueous sulfolane solution, where the conversion of bamboo was 90.0 wt% forming 41.2 mol% of 5-HMF, 20.1 mol% of FF and 24.6 mol% of LA. The synergistic effect of [Sn(OH) 3 (aq)] + and cation polarization has an important role in the outstanding efficiency and specificity of our selective liquefaction system. Moreover, the water/sulfolane system displays excellent performance for maintaining the Lewis acid active sites in [Sn(OH) 3 (aq)] + . In the process, sulfolane regulates the hydrolysis of SnCl 4 to provide an effective Lewis acid strength. This study sheds light on the remarkable potential of the process for future industrial application.
研究领域:
化学工程
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生物质能
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催化化学
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DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
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2024
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IF 2.2
Fangfang Dai,Jiangting Cao,Na Liu,Meiyuan Peng,Chen Wang
In order to separate n-hexane/ethyl acetate (EA) produced in industrial production, the liquid–liquid extraction was used to separate the azeotropic system with sulfolane , 1,2-propanediol and dimethyl sulfoxide (DMSO) as extractants. The liquid–liquid equilibrium (LLE) data of the n-hexane + EA + sulfolane/1,2-propanediol/DMSO were measured at 303.15 K, 313.15 K and 323.15 K. The extraction capacity of the extractants were evaluated by the distribution coefficient (D) and separation factor (S). The LLE data were correlated using the NRTL and UNIQUAC thermodynamic models to obtain binary interaction parameters. The root mean square deviation (RMSD) were all less than 0.02 indicating that the two models were suitable for the phase equilibrium behavior. GUI-MATLAB software was used to test the reliability of the regressed binary interaction parameters. The Dmol 3 module of the Materials Studio was used to analyze σ-profile of n-hexane, EA and extractants and to assess the interaction energy between the components. The results show that sulfolane is the best extractant for the separation of n-hexane + EA.
研究领域:
化学工程
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分离科学
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热力学
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2021
·Vol. 32
·期 1
·2106811
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IF 18.808
Jiahe Liu,Cheng Yang,Xiaowei Chi,Bo Wen,Wenkang Wang,Yu Liu
Aqueous batteries are promising candidates for large-scale energy storage due to their high safety and low cost. However, the narrow electrochemical stability window (ESW, 1.23 V) and high melting point (0 °C) of water limit the energy density and low-temperature operation of aqueous batteries. In this work, sulfolane is introduced as a co-solvent to obtain a water/sulfolane hybrid electrolyte, which participates in the solvated sheath of lithium ions, strengthens the O H bond of water, and disrupts the large-scale hydrogen bond network. Such an elaborate strategy not only expands the ESW of the hybrid electrolyte to 3.8 V, but also lowers the glass-transition temperature to −110 °C. As proof of concept, the LiMn 2 O 4 /Li 4 Ti 5 O 12 full batteries assembled by the hybrid electrolyte display high voltage (2.7 V) and excellent low-temperature performance of 98% capacity retention from 0 to −20 °C, which can even discharge normally and illume an LED light (rated power of 0.02 W, excitation voltage of 1.8 V) at −65 °C.
研究领域:
能源存储技术
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材料科学
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电化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）