Jiaqi Qiu,Mingnv Guo,Zhongqing Yang,Ziqi Wang,Ruiming Fang,Jiang He,Jingyu Ran
A series of novel iodine substitution and oxygen vacancy double defects Bi 2 MoO 6 nanosheets for enhanced photocatalytic reduction of CO 2 is reported, which exhibited superior CO 2 photocatalytic activity and CH 4 selectivity under full solar spectrum illumination. Bi 2 MoO 6 -I2 (the molar ratio of I to Mo is 0.13) has the highest photocatalytic activity, its CO yield is 2.0 times that of pure Bi 2 MoO 6 , the CH 4 yield is 12.2 times that of pure Bi 2 MoO 6 , and the CH 4 selectivity reaches 5.3 times that of pure Bi 2 MoO 6 . Its structure and physicochemical properties were investigated by material characterizations, photoelectrochemical tests and DFT calculations. The enhancement in CO 2 conversion and CH 4 selectivity benefit from: (1) Larger specific surface areas and smaller nanosheets thicknesses facilitate carrier migration; (2) More suitable band structure promotes the reduction of CO 2 ; (3) Insertion of impurity energy levels in the band gap enables efficient jumping of photogenerated electrons; (4) Double defects contribute to efficient CO 2 adsorption and activation; (5) Promoting highly selective conversion of CO 2 to CH 4 by optimising the formation energy of reaction intermediates.
Zhijia Sheng,Chao Zhao,Xiaoyan Huang,Jing Wang,Yi Liu
Hypoxia is a common feature of solid tumors and is considered to be the fatal flaw of conventional photodynamic therapy (PDT), which severely reduces the overall therapeutic efficacy. Here, we developed a series of halogenated photosensitizers to address this issue. The results showed that the introduction of heavy atoms enhanced the spin-coupling effect of the photosensitizers and effectively improved the type I PDT (non-oxygen-dependent) efficiency. The preferred iodine-substituted photosensitizer NRh–I was used as the basic architecture, and further nitrosyl modification was performed to obtain the NO small-molecule prodrug, which was finally encapsulated with DSPE-mPEG 5k to obtain a biocompatible NO nanophotocontrolled prodrug. By using the enhanced permeability and retention effect (EPR), the prodrug system can precisely target the lesion site, release a high concentration of NO by photocontrol, kill the tumor cells, and at the same time, cascade with ROS released with the same “time-space” precision to generate higher cytotoxicity, ONOO − , which generates a stronger targeted synergistic therapeutic effect. This “butterfly effect” strategy maximizes the effect of PDT and broadens the idea of translational medicine.
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