JOURNAL OF ORGANIC CHEMISTRY
·
2024
·
IF 3.3
Hui Xu,Zhi-Jiang Jiang,Yun Jia,Yuhang Su,Jian-Fei Bai,Zhanghua Gao,Jia Chen,Kun Gao
Aromatic sulfones are the prevailing scaffolds in pharmaceutical and material sciences. However, compared to their widespread application, the selective deuterium labeling of these structures is restricted due to their electron-deficient properties. This study presents two comprehensive strategies for the deuteration of aromatic sulfones. The base-promoted deuteration uses DMSO-d6 as the deuterium source, resulting in a rapid H/D exchange within 2 h. Meanwhile, a silver-catalyzed protocol offers a much milder option by using economical D2O to furnish the labeled sulfones.
研究领域:
药物化学
·
材料科学
·
有机合成
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DOI
PubMed
高影响因子
ACS Omega
·
2019
·
IF 2.584
Chao Sun,Wubing Yao,Xu Chen,Yiwen Zhao,Qiqi Wei,Zishuang Chen,Jiashou Wu,Feiyue Hao,Huiping Xie
An environmentally benign, highly efficient, and base-promoted selective amination of various polyhalogenated pyridines including the challenging pyridine chlorides to 2-aminopyridine derivatives using water as solvent has been developed. Featuring the use of the new method, the reaction is extended to the transformation on a large scale. Mechanistic studies indicate that the pathway involving a base aidant dissociation of N,N-dimethylformamide to generate dimethylamine is likely.
研究领域:
有机化学
·
环境化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
·
2021
·
IF 4.354
Long Liu,Yuanyuan Tang,Kunyu Wang,Tianzeng Huang,Tieqiao Chen
A facile and general method for constructing carbon–heteroatom (C–P, C–O, C–S, and C–N) bonds via C–N cleavage of benzyl ammonium salts under transition-metal-free conditions was reported. The combination of t-BuOK and 18-crown-6 enabled a wide range of substituted benzyl ammonium salts to couple readily with different kinds of heteroatom nucleophiles, i.e. hydrogen phosphoryl compounds, alcohols, thiols, and amines. Good functional group tolerance was demonstrated. The scale-up reaction and one-pot synthesis were also successfully performed.
研究领域:
有机化学
·
合成化学
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产品关联
DOI
PubMed
高影响因子
Progress in Natural Science-Materials International
·
2017
·
IF 2.038
Hongbin Dai,Yujie Zhong,Ping Wang
The synthesis of highly active and selective catalysts is the central issue in the development of hydrous hydrazine (N 2 H 4 ·H 2 O) as a viable hydrogen carrier. Herein, we report the synthesis of bimetallic Ni-Ir nanocatalyts supported on CeO 2 using a one-pot coprecipitation method. A combination of XRD, HRTEM and XPS analyses indicate that the Ni-Ir/CeO 2 catalyst is composed of tiny Ni-Ir alloy nanoparticles with an average size of around 4 nm and crystalline CeO 2 matrix. The Ni-Ir/CeO 2 catalyst exhibits high catalytic activity and excellent selectivity towards hydrogen generation from N 2 H 4 ·H 2 O at mild temperatures. Furthermore, in contrast to previously reported Ni-Pt catalysts, the Ni-Ir/CeO 2 catalyst shows an alleviated requirement on alkali promoter to achieve its optimal catalytic performance.
研究领域:
催化化学
·
材料科学
·
能源化学
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产品关联
DOI
高影响因子
Reaction Kinetics Mechanisms and Catalysis
·
2016
·Vol. 118
·期 2
·605-619
·
IF 1.265
Wang Lei,Zhang Chuanhui,Huang He,Li Xuebing,Zhang Wei,Lu Mohong,Li Mingshi
MnO
x
catalysts were contrastively prepared by an alkali-promoted redox precipitation strategy (MnO
x
-RP) and a conventional citrate sol–gel method (MnO
x
-SG), and tested for the catalytic oxidation of toluene, where MnO
x
-RP exhibited higher catalytic activity, excellent catalytic durability under dry conditions and good regeneration ability under humid conditions. The characterizations results indicated that different crystalline phases but similar textual properties (specific surface area, porosity and morphology) were observed over MnO
x
-RP and MnO
x
-SG catalysts, while MnO
x
-RP presented significantly higher low-temperature reducibility and average oxidation state of Mn as well as higher abundance of surface adsorbed oxygen species compared with MnO
x
-SG, thus beneficially resulting in its superior catalytic activity in the reaction.
研究领域:
化学工程
·
环境科学
·
材料科学
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DOI
高影响因子
TALANTA
·
2019
·
IF 4.916
Li Su,Xinai Yu,Yuqi Miao,Guojiang Mao,Wenpei Dong,Suling Feng,Siman Liu,Like Yang,Kaige Zhang,Hua Zhang
Nanozymes’ activities could be regulated by a simple and effective pH change in an in situ manner. In this work, for the first time, the peroxidase-like activity of Ni/Co layered double hydroxides (LDHs) was regulated via the alkaline-promoted reaction of fluorogenic substrate homovanillic acid and H 2 O 2 , and a promising tool for pH sensing was developed over the pH range of 8.3–9.6. As peroxidase nanozyme model, Ni/Co LDHs showed ease of preparation, low-cost, and water-solubility, which played an important role in this luminescence system. Based on the pH-dependent regulation of the Ni/Co LDHs activity, we constructed the bioassay platform for the determination urea, urease, penicillin G, and penicillinase with a wide linear range of 17–1000 µM, 3.3–270 mU mL −1 , 3.3–1300 µM and 3.3–100 mU mL −1 , respectively. This study not only demonstrated the alkaline-promoted modulation the nanozymes’ activities, but also established a facile approach to develop novel bioassays.
研究领域:
生物化学
·
分析化学
·
生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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