SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2025
·
IF 4.6
Xiaoya Kou,Shiyi Yang,Jing Zou,Siying Chen,Jianying Wu,Bo Sun,Zhongda Yan,Dezhao Liu,Haoqiang Tan
Recently, increasing attention had been paid for using peracetic acid (PAA) as an efficient disinfectant or a strong oxidant in wastewater treatment. In this study, a rapid and simple spectrophotometric method for the selective determination of PAA in aqueous solution was established, based on the oxidative decolorization of rhodamine B (RhB) by reactive species generated from the combination of PAA and Co(II). Under the optimized conditions (20 μmol L −1 RhB, 1.0 mmol L −1 Co(II), pH = 5.0 buffered with 10 mM acetate acid buffer, and reaction time = 40 s), the extent of RhB decolorization at the characteristic wavelength of 552 nm was found to be proportional to the concentration of PAA in the aqueous solution. A strong linear correlation was observed between the consumption of RhB and the concentration of PAA in the range of 0.25–25 μmol L −1 (R 2 = 0.9991), and the sensitivity for PAA was as high as 2.99 × 10 4 M −1 cm −1 . The RhB spectrophotometric method is effectively tolerant to interference the coexistent H 2 O 2 in PAA solution, the common coexisting species in practical water samples (KCl, MgSO 4 , NaNO 3 , NaHCO 3 , DCF and humic acid) and even the added reducing substances such as hydroxylamine and ascorbic acid. As a selective colorimetric agent, RhB is resistant to interference from reducing substances and water bodies, enabling accurate determination of PAA concentration in actual water environments. Overall, the RhB spectrophotometric method could be used as an alternative method for the cheap, rapid and selective determination of PAA in water samples.
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JOURNAL OF HAZARDOUS MATERIALS
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2025
·
IF 11.3
Qing Bai,Qian-Yuan Wu,Yun-peng Wu,Yu-jia Nong,Zi-Bo Jing,Min-Yong Lee,Wen-Long Wang
Nitrate photolysis under UV222 irradiation has increasingly attracted attention as an advanced oxidation process, while fundamental mechanisms remain incompletely understood in various water matrices. This study revealed that the observed nitrate photodecay under UV222 represented a dynamic balance between innate photolysis and significant reformation, with the innate quantum yield (0.52 mol·Ein −1 ) substantially 7.1–11.0 times higher than the observed quantum yield (0.047–0.073 mol·Ein −1 ). Inorganic carbon (IC) and organic carbon (OC), ubiquitous water matrix components, influenced UV222/nitrate through distinctly different mechanisms: IC suppressed nitrate photodecay 12.6–58.3 % via enhancing ONOO⁻-mediated nitrate reformation without affecting innate photolysis, while OC promoted observed nitrate photodecay 19.6–54.5 % by scavenging reactive intermediates involved in nitrate reformation. UV222/nitrate effectively degraded various micropollutants via direct photolysis (e.g., N-nitrosodimethylamine), • OH oxidation (e.g., carbamazepine), and a combination of pathways including reactive nitrogen species (RNSs) oxidation (e.g., sulfamethoxazole). IC selectively promoted RNSs oxidation while suppressing • OH oxidation pathway, leading to selective effects for various micropollutant degradation and the increased nitration byproducts formation. In contrast, OC uniformly reduced all oxidation pathways through non-selective scavenging of reactive species. This mechanistic understanding explained the complex effects of water matrix components on UV/nitrate performance and provides a fundamental basis for optimizing UV222 driven advanced oxidation processes for micropollutant control in diverse water conditions.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Like Wang,Peiyan Feng,Bo Liu,Shuheng Wei,Peng Tang,Shouwei Yin
Novel phase-change Pickering emulsion microcapsules (PCPEs) were constructed using tannic acid (TA)-modified zein nanoparticles (T-zein) and a lauric acid/stearic acid eutectic (LS) to encapsulate β-carotene. The grafting of TA tuned the wettability of zein nanoparticles, enabling stable emulsification at 50 °C. Subsequent cooling resulted in microcapsules with a T-zein shell and crystalline core (LS), achieving an encapsulation efficiency of 88.15 %. The solidified oil phase restricted molecular migration, while interfacial T-zein provided dual protection, reducing β-carotene degradation under UV irradiation and auto-oxidation by 57.19 % and 67.88 %, respectively, compared with liquid-core emulsions. In vitro digestion studies showed that phase change triggered by physiological temperature enabled controlled release. PCPEs displayed superior gastric stability and resistance to coalescence in the intestine, enhancing the bioaccessibility of β-carotene to 42.57 % (36 % higher than liquid-core emulsions and 298 % of the free control). Overall, this solid-core engineering strategy presents a novel platform for the rational design of emulsion for targeted delivery of lipophilic bioactives.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
·
IF 5.4
Bingxian Niu,Yuxia Wang,Yu Han,Pan Zhang,Yonghong Cai,Yufeng Wu,Linlin Zhao,Ying Xu
This paper presents the synthesis of a novel polyaspartate derivative (PASP-BBA) with both corrosion inhibition and antibacterial properties. The compound is synthesised using polysuccinimide (PSI), 1,4-bis(3-aminopropyl)piperazine (BAPP) and bromoacetic acid (BA) as raw materials. By controlling the degree of polymerisation, a BAPP grafting rate of 55 % is achieved. The corrosion inhibition performance of PASP-BBA was evaluated using electrochemical methods and weight loss method. The potentiodynamic polarization results indicated that at a concentration of 70 mg/L, the corrosion inhibition efficiency of PASP-BBA was 54.28 %, which was 33.53 % higher than that of PASP. The study on the corrosion inhibition mechanism of PASP-BBA through quantum chemical calculations showed that PASP-BBA achieved this effect through physical and chemical adsorption, adhering to the surface of carbon steel and reducing the contact with corrosive media. The antibacterial performance was evaluated using filter paper method and dilution plating method. The research results indicated that PASP-BBA has selective antibacterial effects and can effectively inhibit Escherichia coli . When the concentration of PASP-BBA was 100 mg/mL, the survival rate of Escherichia coli dropped to 21 %. Meanwhile, Bacillus cereus could survive, thereby enhancing the dual functions of polyaspartic acid derivatives in corrosion inhibition and antibacterial applications. This study provides certain theoretical references for the design of green multifunctional water treatment agents.
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ANALYTICA CHIMICA ACTA
·
2025
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IF 6
Yanping Xing,Xixiang Xie,Jiangtao Liu,Tao Zhao,Xiyu Liu,Pan Wu,Faquan Lin,Yong Huang
The tumor-associated autoantibody against senescence marker protein-30 (SMP30) serves as a critical serum biomarker for the early detection of hepatocellular carcinoma (HCC), enabling rapid and non-invasive cancer diagnosis and monitoring. However, the accurate detection of the SMP30 antibody remains challenging due to the complex composition of blood and the heterogeneity of circulating antibodies. This study introduces a highly sensitive and straightforward method for SMP30 antibody detection, utilizing a graphene oxide-Hemin (GO-Hemin) composite nano-mimetic enzyme in combination with ferrocenyl-tyramine (Fc-Tyr)-mediated tyramine signal amplification (TSA) within microtiter wells. A solid-phase protein with high affinity selectively captures the SMP30 antibody, while the target is identified via nano-mimetic enzyme labeling of a secondary antibody. The subsequent nano-enzymatic reaction facilitates the deposition of Fc-Tyr, generating a strong electrochemical signal. The biosensor achieves high sensitivity through enhanced electrochemical transduction and minimal spatial resistance at the electrode interface. By integrating immunocapture specificity with electrochemical amplification, this approach enables high-throughput analysis in clinical applications. Experimental results demonstrate that this biosensor can detect smp30 antibodies at concentrations as low as 0.1086 ng/mL, with a detection range spanning 0.1 ng/mL to 1 μg/mL. Analysis of authentic serum samples confirmed that when combined with ELISA, the sensor accurately measured SMP30 antibody levels in serum samples from clinical hepatocellular carcinoma patients. The results demonstrated consistent detection outcomes with recovery rates ranging from 93 % to 104 % and relative standard deviations (RSD) between 1.2 % and 3.7 %. This platform provides a practical and efficient tool for detecting SMP30 antibodies and holds broader application potential in tumor marker monitoring and cancer diagnosis.
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Journal of Future Foods
·
2025
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IF 7.2
Zhen Liu,Yu-mei Zhai,Wen-zhu Guo,Lu Chang,Chong Yu,Sheng-Ming Lei,Yun-Guo Liu
Ultra-high-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF-MS/MS) was used to detect the metabolites during the withering process of rose white tea to find out the differential metabolites, and headspace solid-phase microextraction–gas chromatography–mass spectroscopy (HS–SPME–GC–MS) was used to detect flavor compounds during the withering process of rose white tea and identify characteristic aroma compounds. By studying the flavor characteristics during the withering process, the reasons for the formation of the aroma of rose white tea can be revealed, providing a theoretical basis for the development of new tea products. There was a significant positive correlation (p<0.05) between total flavonoids and benzoids, organoheterocyclic compounds. The contents of compounds such as linalool, trans-cinnamic acid, L-phenylalanine, tyramine, indole-3-acrylic acid, and valine gradually rose during withering, yet declined subsequent to drying. The moisture content, total phenol content, and hydroxyl radical scavenging activity showed a negative correlation with the withering time. GC-MS results showed that 148 flavor compounds were identified in rose white tea, with linalool, citronellol, geraniol, phenylethanol, citral, phenylacetate, and methyl eugenol identified as the main contributors to the aroma characteristics of rose white tea. Citronellyl acetate and 2-undecanone were characteristic aroma compounds during the rose withering stages (WT0-WT48). The concentrations of citronellyl acetate exhibited an initial increase followed by a subsequent decline (WT0: 2.347mg/kg; WT12: 2.455mg/kg; WT24: 3.646mg/kg; WT36: 3.176mg/kg; WT48: 1.217mg/kg;). Phenylacetaldehyde and cyclotridecanone were unique aroma compounds found in dried rose white tea (HAD).
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Foods
·
2025
·Vol. 14
·期 19
·3423
·
IF 5.1
Chi Zhang,Xin Liu,Tailong Cai,Jianfeng Ping,Yibin Ying
Accurate and rapid extraction of pesticide residues in fruits is crucial for timely food safety monitoring. However, conventional extraction methods remain labor-intensive and time-consuming, often requiring hours for sample preparation. Here, we present a porous hydrogel microneedle (HMN) patch integrated with an automated insertion applicator as a highly efficient platform for the rapid extraction of peach juice for imidacloprid residue detection. The HMN patch, composed of polymethyl vinyl ether/maleic anhydride (PMVE/MA) polymer, was fabricated with high porosity by adjusting the porogen content. Under optimized porogen content of 3% NaHCO 3 , the developed HMN patch exhibited ultrahigh extraction efficiency, achieving a 40-fold water absorption capacity and extracting 0.6% ( w / w ) peach solids of its weight within 5 min. The extracted juice could be readily recovered through a simple elution process and was directly compatible with both high-performance liquid chromatography (HPLC) analysis and lateral flow assays. Compared with conventional destructive methods, the HMN platform offers a scalable, high-efficiency, and user-friendly solution for high-throughput pesticide extraction. The integration of the automated applicator further enhances consistency, minimizes user variability, and facilitates on-site monitoring of pesticide residues, providing a practical pathway for field-deployable food safety monitoring.
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CHEMISTRY & BIODIVERSITY
·
2025
·
IF 2.5
Linlin Cui,Zheng Xu,Yu Zhu,Xuan Liu,Shihao Li,Li Zhao,Zhihua Xing,Guanghuan Shen
This study aimed to design and synthesize a series of novel cordycepin derivatives featuring urea groups to explore the antitumor efficacy of natural product derivatives with enhanced potency. The structures of the target compounds were characterized using infrared spectroscopy (IR), proton/carbon nuclear magnetic resonance spectroscopy ( 1 H and 13 C NMR), high-performance liquid chromatography (HPLC), and high-resolution mass spectrometry (HRMS). In vitro activity against MCF-7, HepG-2, SGC-7901, and HK-2 cells was evaluated using the standard methyl thiazolyltetrazolium assay (MTT), revealing that compound 4l exhibited significant inhibitory effects on HepG-2 cells (IC 50 = 14.86 ± 2.37 µM), outperforming cordycepin. Mechanistic studies indicated that 4l induced dose-dependent apoptosis, arrested the cell cycle at the G 0 /G 1 phase, and activated the intrinsic mitochondrial pathway. Molecular docking simulations further elucidated its binding mode with target proteins. Collectively, compound 4l shows promise as a candidate drug for liver cancer therapy. Graphical Synthesis of a Series of Cordycepin Derivatives and Their Antitumor Activity Study.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Hongjiang Peng,Yanyu Song,Gongjie Hua,Jinhong Wu,Fuwen Liu,Kuangfei Lin,Cong Lu
Peroxymonosulfate (PMS) activation through non-radical pathways exhibits high efficiency and selectivity for pollutant degradation. However, the complex regulation of catalytic active centers makes the generation of 1 O 2 challenging. In this work, Beta zeolite with uniformly dispersed Al-Ov-Co active sites (Co-Beta zeolite) was synthesized via a simple impregnation method, which exhibits excellent 1 O 2 steady-state generation concentration (2.46 × 10 −11 M) at extremely low doses (0.05 g/L). Compared with the original Co 3 O 4 , Co-Beta zeolite displays significantly enhanced PMS activation efficiency, and the apparent reaction rate constant for degrading tetracycline hydrochloride (CTC) increases by 4.7 times. Pyridine infrared characterization confirms that cobalt ions occupy the Brønsted acid sites of the Beta zeolite and undergo proton exchange with them. Accompanied by the redistribution of electrons during the calcination process, some lattice oxygen in the material is removed to form Al-Ov-Co sites. The proportion of Co 2+ in the Al-Ov-Co sites dramatically increases, thereby ensuring efficient activation of PMS. As PMS is adsorbed onto the Al-Ov-Co sites, the H atom of PMS directly bonds with the O atom in Co-Beta zeolite, while the O atom in PMS forms a bond with Co 2+ . After the H O and S O bonds of PMS are broken, abundant 1 O 2 is produced. In practical application evaluation, Co-Beta zeolite shows satisfactory anti-interference ability, reliable cycling stability and acceptable metal leaching. This work inspires the design of highly-dispersed Co 2+ to promote non-radical pathways for PMS-activated water purification.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Xiaofeng Liu,Ruiji Wang,Fayou Tian,Hao Ren,Jinglin Wang,Yan Lin,Zhongtao Li,Mingbo Wu
Development of electrocatalytic reduction of carbonyl compounds for carbon‑carbon (C C) coupling represents an effective pathway to achieve sustainable synthesis of multi‑carbon chemicals. The hydrogen evolution reaction (HER) is considered the most significant competitive process, which could be suppressed by weakening the adsorption of protons on interface or by making protons in the electrolyte inactive through the use of certain additives. However, increasing the coverage of protons and carbonyl molecules are necessary to facilitate the generation of hydrogenation intermediates during C C coupling. To reconcile this contradiction, a Ni-based catalyst for electrocatalytic coupling of formaldehyde has been developed, decorated with phosphate groups around Ni sits. The following enhancement could be achieved: 1) Ni sites enhance the adsorption of formaldehyde on catalyst surface and promote their electroreduction; 2) Phosphate groups near the Ni sites can act as protons affinity sites to prevent their self-coupling. As the result, the adsorbed HCHO and hydrogen can be balanced to facile the formation of intermediate *CH 2 OH during C C coupling. Consequently, the PD-Ni/C@CP catalyst exhibits outstanding performance in the continuous preparation of ethylene glycol, with a production rate of 22 mmol/(L·min) and a Faradaic efficiency exceeding 90%, highlighting its potential for the efficient and sustainable synthesis of other high-value chemicals.
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Analytical Methods
·
2026
·
IF 3
Xixuan Chen,Lei Zheng,Rongzhen Ma,Phong H. N. Vo,Jiaxin Ni,Songjun Guo
This study presents an improved ethanol-mediated solvothermal method for synthesizing malic acid/urea-derived carbon dots (MUCDs) for the highly selective and sensitive detection of mercury ions (Hg2+). The detection limit was enhanced by over an order of magnitude compared to previous methods employing similar precursors, achieving a limit of detection of 88.46 nmol L−1, which meets the European Union standard for mercury discharge in industrial wastewater (250 nmol L−1). Pyrophosphate (P2O74−) has been used as a highly effective masking agent for Fe3+, substantially boosting the probe's performance in complex matrices. With practical application in mind, the environmental safety of these carbon dots was proactively evaluated using a zebrafish model. The assessment demonstrated no significant toxicity at concentrations up to 100 mg L−1, establishing a 10-fold safety margin relative to the operational dosage. Fluorescence imaging revealed accumulation specifically in the intestinal tract, with no distribution to vital organs, confirming their environmental safety. Under optimized conditions, the MUCDs achieved a quenching efficiency of 0.82 in the presence of 25 µmol per L Hg2+ at a concentration of 10 mg L−1, while also demonstrating thermal stability and pH tolerance. Spike-recovery tests in tap water, river water, and metallurgical wastewater samples yielded satisfactory recoveries ranging from 93.85% to 101.86%. Based on the characterization of MUCDs and the MUCDs–Hg2+ complex, the observed quenching mechanism was explained by chelation between Hg2+ and surface functional groups, leading to aggregation, static quenching, and enhanced Rayleigh scattering. This study highlights the critical importance of incorporating comprehensive environmental safety assessments into the development of functional nanomaterials.
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Xinyu Luo,Dejin Lin,Jingqi Wang,Yihao Zhang,Xinru Liu,Sineng Gao,Da Chen
High-performance and on-site detection of pesticide glyphosate (GLY) residue is particularly urgent and challenging. Herein, dual-emission nitrogen-doped carbon dots (N-CDs) synthesized from tris-hydroxymethyl-aminomethane and resorcinol are successfully developed as a ratiometric fluorescence sensor. Upon adding GLY, the fluorescence intensity of N-CDs at 425 nm is quickly quenched via aggregation-caused quenching and photoinduced electron transfer, leading to the complexation process of N-CDs with GLY. While the fluorescence intensity of N-CDs at 525 nm with little change can be served as the reference signal. This distinct ratiometric fluorescence sensor achieves the detection limit and quantification limit as low as 24 nM and 80 nM with a wide linear range of 0.024–30 μM, respectively. Moreover, a smartphone-integrated lateral flow visual sensing platform is established for GLY detection by capturing and identifying the parameters of color variations. This platform represents a potential for the quantitative monitoring of GLY residue in food and the environment.
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