LANGMUIR
·
2021
·
IF 3.882
Chijia Wang,Shupei Liu,Meiling Li,Zihua Wang,Hongxin Luo,Weihao Fan,Zhanjian Liu,Fatang Liu,Huaiyuan Wang
Metal pipes in industrial production are exposed to various corrosive ions. The combined action of these ions with oxygen in water causes corrosion and contamination of the metal pipes and equipment. In addition, metallic ions in water react with anions to form scale on the surface of the metal, which significantly reduces the service life of the metal and equipment, resulting in safety hazards. Waterborne coatings have attracted tremendous attention due to the less negative impact on the environment, but their practical applications are severely restricted by poor barrier properties and poor mechanical durability. Herein, the barrier properties of water-based coatings are successfully improved by adding functional slow-release nanofillers, and the fillers also endow the coating with excellent antiscaling properties. A functional slow-release nanofiller (lecithin/SiO2/HEDP) was prepared using HEDP (etidronic acid) as the scale inhibitor active material and SiO2 as the carrier, combined with a phospholipid membrane with slow-release permeability. With the addition of slow-release fillers, compared with the EP coating, the impedance modulus of composite coatings increases about 1 order of magnitude, the scale inhibition rate is as high as 80.7%, and the antiscaling life is double that of the coating without the phospholipid-coated filler. Thus, this study is expected to provide a new perspective for the preparation of new slow-release fillers and high-efficiency scale inhibitor coatings.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2023
·
IF 6.1
Lichun Chen,Songwen Xue,Binhao Dai,Yifei Wang,Huimin Zhao
Molecular permeation through phospholipid membranes is a fundamental biological process for small molecules. Sucrose is one of the most widely used sweeteners and a key factor in the pathogenesis of obesity and diabetes, yet a detailed understanding of its mechanism involved in permeability into phospholipid membranes is still lacking. Here, using giant unimolecular vesicles (GUVs) reconstituting membrane properties, we compared the osmotic behavior of sucrose in GUVs and HepG2 cells to explore the effect of sucrose on membrane stability in the absence of protein enhancers. The results suggested that the particle size and potential of GUVs and the cellular membrane potential changed significantly with increasing the sucrose concentration (p < 0.05). In microscopic images of cells containing GUVs and sucrose, the fluorescence intensity of vesicles was 537 ± 17.69 after 15 min, and the value was significantly higher than that of microscopic images of cells without sucrose addition (p < 0.05). These changes suggested that the permeability of the phospholipid membrane became larger under a sucrose environment. This study provides a theoretical basis for better insight on the role of sucrose in the physiological environment.
研究领域:
生物物理学
·
细胞生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Zongqi Yang,Xinyu Yu,Bo Huang,Jiahui Li,Xiaohai Yan,Kewei Feng,Rui Cai,Yahong Yuan,Tianli Yue,Qinglin Sheng
Breath ammonia detection is a promising non-invasive method for diagnosing Helicobacter pylori infections. However, existing breath ammonia vapor detection techniques face challenges, including high costs, prolonged processing times, complex procedures, and limited selectivity. This study presents a novel sensor based on phospholipid membrane-encapsulated perovskite quantum dots, integrated onto a glass cellulose membrane using electrospinning. The developed sensor undergoes a substitution reaction with ammonia, causing a significant decrease in fluorescence intensity and a visible color change from yellow to colorless. Consequently, a high-sensitivity and high-selectivity sensor for fluorescent quenching and visual detection of breath ammonia vapor was established. The sensor shows a limit of detection of 0.22 ppm, with linear correlations between fluorescence intensity, RGB color changes and ammonia concentration. Compared to traditional perovskite quantum dots, the sensor exhibits enhanced water stability and extended fluorescence lifetime. Additionally, it features rapid response, high stability, and excellent selectivity for ammonia. This sensor demonstrates promising potential for non-invasive detection of Helicobacter pylori infections, offering a new approach for fluorescence-based and visual detection of breath ammonia.
研究领域:
生物医学工程
·
医学诊断
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2021
·Vol. 26
·期 11
·3265
·
IF 4.412
Yuhao Sun,Xiaolin Chen,Hong Liu,Song Liu,Huahua Yu,Xueqin Wang,Yukun Qin,Pengcheng Li
Avian leukosis virus subgroup J (ALV-J) is an immunosuppressive virus which has caused heavy losses to the poultry breeding industry. Currently, there is no effective medicine to treat this virus. In our previous experiments, the low-molecular-weightSargassum fusiformepolysaccharide (SFP) was proven to possess antiviral activity against ALV-J, but its function was limited to the virus adsorption stage. In order to improve the antiviral activity of the SFP, in this study, three new SFP long-chain alkyl group nanomicelles (SFP-C12M, SFP-C14M and SFP-C16M) were prepared. The nanomicelles were characterized according to their physical and chemical properties. The nanomicelles were characterized by particle size, zeta potential, polydispersity index, critical micelle concentration and morphology. The results showed the particle sizes of the three nanomicelles were all approximately 200 nm and SFP-C14M and SFP-C16M were more stable than SFP-C12M. The newly prepared nanomicelles exhibited a better anti-ALV-J activity than the SFP, with SFP-C16M exhibiting the best antiviral effects in both the virus adsorption stage and the replication stage. The results of the giant unilamellar vesicle exposure experiment demonstrated that the new virucidal effect of the nanomicelles might be caused by damage to the phospholipid membrane of ALV-J. This study provides a potential idea for ALV-J prevention and development of other antiviral drugs.Keywords:Sargassum fusiforme;polysaccharide;long-chain alkyl group;antiviral activity;ALV-J
研究领域:
兽医学
·
药理学
·
分子生物学
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
Small
·
2021
·Vol. 17
·期 46
·2103255
·
IF 13.281
Menglu Li,Yujing Zeng,Xinyu Qu,Mohammed Jalalah,Saeed A. Alsareii,Chao Li,Farid A. Harraz,Genxi Li
CsPbX 3 perovskite nanocrystals (NCs), with excellent optical properties, have drawn considerable attention in recent years. However, they also suffer from inherent vulnerability and hydrolysis, causing the new understanding or new applications to be difficultly explored. Herein, for the first time, it is discovered that the phospholipid membrane (PM)-coated CsPbX 3 NCs have intrinsic biocatalytic activity. Different from other peroxidase-like nanozymes relying on extra chromogenic reagents, the PM-CsPbX 3 NCs can be used as a self-reporting nanoprobe, allowing an “add-to-answer” detection model. Notably, the fluorescence of PM-CsPbX 3 NCs can be rapidly quenched by adding H 2 O 2 and then be restored by removing excess H 2 O 2 . Initiated from this unexpected observation, the PM-CsPbX 3 NCs can be explored to prepare multi-color bioinks and metabolite-responsive paper analytical devices, demonstrating the great potential of CsPbX 3 NCs in bioanalysis. This is the first report on the discovery of nanozyme-like property of all-inorganic CsPbX 3 perovskite NCs, which adds another piece to the nanozyme puzzle and opens new avenues for in vitro disease diagnostics.
研究领域:
纳米技术
·
生物化学
·
分析化学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）