MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yuteng Hang,Rusha Gopali,Xiaorong Mao,Ling Zhu,Mengyang Tao,Guangjie Gu,Feng Li,Zhangxuan Liu,Xinnan Li,Ruyu Jiang,Xinxin Xu,Ning Bao,Yang Liu
Elevated cholesterol is a major cardiovascular risk factor, but current detection methods are resource-intensive. Non-invasive point-of-care testing is promising yet limited by sensitivity, and the blood-saliva cholesterol correlation requires further investigation. We developed an electrochemical biosensor featuring cholesterol oxidase immobilized on screen-printed carbon electrodes (SPCE) modified with conductive Au-Ag@Au core-shell nanoparticles and Prussian blue/poly-3,4-ethylenedioxythiophene (PB-PEDOT) nanocomposites. Morphological, spectroscopic, and electrochemical analyses (including impedance spectroscopy, heterogeneous electron transfer kinetics, and active surface area quantification) confirmed the biosensor superior conductivity. The biosensor achieved exceptional performance: a broad linear range (0.01–1.0 mM), low detection limit (3.3 μM amperometric LOD; 2.8 μM via EIS), and high sensitivity (57.3 μA/mM·cm 2 amperometric; 781 Ω/mM·cm 2 impedimetric). Clinical validation demonstrated excellent agreement with standard colorimetric methods in human serum and saliva for cholesterol tested in biological compounds and robust stability. A strong serum-saliva correlation (Pearson's correlation coefficient as 0.928) supports noninvasive monitoring feasibility. The anti-interference capability of the proposed biosensor was evaluated against common interferents, including glucose, lactic acid, uric acid, ascorbic acid, bovine serum albumin, cysteine, and their mixture. The results confirmed its high specificity against these typical biological matrix components. Particularly significant is its non-invasive detection capability, which eliminates the need for painful blood draws or invasive sample collection procedures. A key innovation lies in the synergistic integration of conductive Au-Ag@Au core-shell nanoparticles with PB-PEDOT nanocomposites on SPCEs, which significantly enhances electron transfer and catalytic activity, yielding an exceptionally sensitive and stable sensing platform. The biosensor sets itself apart by achieving superior analytical performance concurrently with robust clinical validation in both serum and saliva, firmly establishing its potential for reliable non-invasive cholesterol monitoring.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2025
·Vol. 36
·期 30
·1-13
·
IF 2.8
Huang Yi-Rui,Li Wei,Wang Ze-Hong,Jian Xiao-Jian,Zhou Zi-Zhe,Jia Xiang-Xiang,Liu Hong-Yu,Lu Yi-Fan,Wang Jun-Chuan,Wu Xiang-Feng,Wang Hui,Zhou Er-Peng
Chiral optoelectronic sensors detect chirality by selectively binding with chiral substrates, causing changes in electrical signals, which have attracted wide attention for their chiral recognition ability. In this study, the Ti 3 C 2 /ZIF-67/D-His electrochemical sensors were successfully synthesized. Firstly, ZIF-67/D-His was obtained using hexahydrated cobalt nitrate, dimethylimidazole, and D-histidine (D-His). Then, the ZIF-67/D-His film was grown on the surface of the Ti 3 C 2 film using a spin-coating method. By changing the spin-coating cycles, the influence of the ZIF-67/D-His film thickness on the detection performance was studied. The results showed that when the spin-coating cycle was three, the electrochemical sensor (Ti 3 C 2 /ZIF-67/D-His-3) exhibited good detection performance for D-Ala with a detection limit of 1.1 μM, and additionally demonstrated an excellent selective detection ability for D-Ala, with a significant difference in the differential pulse voltammetry (DPV) current intensity between D-Ala and L-Ala solutions. Besides, the detection curve for D-Ala showed a linear relationship with the concentration of the D-Ala solution. Furthermore, the Ti 3 C 2 /ZIF-67/D-His-3 electrochemical sensor demonstrated good stability and could be reused multiple times after simple cleaning. The Ti 3 C 2 /ZIF-67/D-His prepared in this work shows promising application potential in the area of electrochemical sensors.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Qi Liang,Tao Liao,Liqin Zhu,Changxiang Liu,Qian Liu,Jianhua Xiong,Ruiping Deng,Xiaoning Liao
A novel nanocomposite consisting of core (Cu)-shell (Ag) nanoparticles encapsulated in carbon nanotubes (CTs) grown on a MOF-derived carbon framework was synthesized by in-situ pyrolyzing method. After further modification with multi-walled carbon nanotubes (MWCNTs), a hierarchical porous carbon network confined core (Cu)-shell (Ag) bimetal (Cu@Ag@CTs/MWCNTs) with excellent catalytic properties to isoproturon (ISO) and norfloxacin (NOR) was obtained. The electrochemical sensor based on the Cu@Ag@CTs/MWCNTs can simultaneously detect the ISO and NOR with excellent sensitivity, good selectivity and perfect stability as well as a separation of peak potential of 270 mV. The calibration curves for ISO and NOR achieved by the proposed sensor range from 80 nM to 18 μM and 7.0 nM to 1.7 μM with detection limits of 26 nM and 2.0 nM, respectively. Moreover, the sensor shows good recoveries in simultaneous detection of ISO and NOR in real sample analysis, highlighting its high feasibility in practical application.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Qi Li,Xiao Xiao,Yue Wang,Rui Wang,Qinzhi Wang,Wei Wu
In this work, a versatile conductive bimetallic metal–organic framework combined with aptamer enhanced electrochemical biosensor based on glassy carbon electrode (CMOF/Apt/GCE) was successfully developed for highly sensitive and selective detection of E. coli O157:H7 in animal derived food. The CMOF with large surface area provided an abundance of binding sites for aptamers, which greatly enhancing the selectivity of sensor for E. coli O157:H7. Furthermore, the excellent conductivity of CMOF dramatically improves the electron transfer rate on the modified surface of GCE, contributing to sensitively sensing of E. coli O157:H7. Based on CMOF/Apt/GCE, the E. coli O157:H7 was detected with a low limit of 2.5 CFU·mL −1 and a wide detection range from 10 to 10 7 CFU·mL −1 , superior than those of most previous works. Moreover, it can be applied to pork, chicken, and shrimp samples with good recovery, which indicated its great potential in practical food safety monitoring.
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INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
·
2026
·
IF 5.7
Hui Jiang,Hui Du,Donglei Jiang,Xinmei Liu,Haijing Wu,Mengjing Huang,Rui Sun,Xiaojie Sun,Siqi Zeng,Yanmin Ju,Jun Yang
Staphylococcus aureus enterotoxin B (SEB) is a leading cause of foodborne illness. In this study, we developed a time-resolved fluorescent immunochromatography test strip (TRFITS) combined with a hydrogel microneedle patch (HMNP) and machine learning (ML) for the rapid detection of SEB in salmon. The developed HMNP, fabricated from methacrylated gelatin, can automatically extract 37 mg of interstitial fluid within 6 min. We then conducted TRFITS analysis on salmon samples to detect SEB and ML algorithms so as to predict its concentration. This method enabled efficient sampling and accurate quantification of SEB within 32 min, with a limit of detection (LOD) of 4.63 ng/mL. In addition, ML-assisted TRFITS applied to salmon demonstrated that the YOLOv11 model achieved a prediction accuracy of 91.3% and a lower LOD of 2 ng/mL. These findings highlight a novel approach toward on-site SEB detection with significant implications for food safety monitoring and point-of-care diagnostic applications.
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RSC Advances
·
2026
·Vol. 16
·期 13
·11972-11987
·
IF 6.1
Min Zheng,Yangyi Wang,Yiheng Liu,Xiaoyan Jiang,Yannan Zhang,Jinghao Huo
Microplastic pollution is widespread, infiltrating water bodies and soil, entering the food chain, and thereby posing threats to ecosystems and human health. In this study, anatase titanium dioxide (TiO2) was prepared via a hydrothermal method and subsequently modified with bio-based carbon quantum dots (CQDs). The composite exhibited optimal performance when the concentration of the carbon source (citric acid) was 0.17 M, yielding carbon dots with an observable size of approximately 4.18 nm. The formation of Ti–O–C chemical bonds between the carbon dots and TiO2 was observed. Compared to pristine TiO2, the CQDs@TiO2 composite displayed a reduced bandgap, significantly enhanced light absorption in the visible region, improved photogenerated charge carrier transport, and suppressed non-radiative recombination, leading to a substantial enhancement in photocatalytic performance. The CQDs@TiO2 photocatalyst was employed for the photodegradation of polyethylene terephthalate (PET) and polylactic acid (PLA) microplastics under visible light irradiation. The results indicated that under illumination at 100 mW cm−2 in a pH 8 buffer solution, CQDs@TiO2 effectively catalyzed the degradation of alkali-pretreated PET and PLA microplastic samples, with 48 h degradation rates of 28.9% and 59.8%, respectively. The degradation of both types of plastics primarily relied on the synergistic action of 1O2, h+, ˙O2− and ˙OH generated by the photocatalyst, both undergoing a degradation process centered on the cleavage of ester bonds. This study not only demonstrates the superior photocatalytic efficacy of the CQDs@TiO2 composite but also establishes it as a viable strategy for mitigating the urgent challenge of microplastic pollution under near-natural conditions.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 2
·122009
·
IF 7.5
Xingyu Guo,Haiyan Song
Photocatalytic H 2 O 2 production from O 2 using covalent organic frameworks (COFs) is a promising solar-to-chemical energy conversion route. However, existing design strategies for COF-based photocatalysts are constrained by various issues, making it difficult to achieve synergistic optimization of both photogenerated charge separation efficiency and catalytic activity. In addition, compared with pure water medium, achieving efficient H 2 O 2 production in alcohols is of great significance for alcohol-mediated organic synthesis and direct alcohol fuel cells. Herein, two amide-linked COFs were fabricated via site-specific benzene ring functionalization, focusing on precise amino group incorporation. Aligned with recent advances in photocatalytic structure property relationships, amino group introduction induces significant charge density differentials in COFs, modulating donor acceptor interactions and efficiently promoting photogenerated charge separation/transport. Consequently, the 2-aminoterephthalic acid-based COF (PPTD-COF) exhibits superior photocatalytic H 2 O 2 production performance. PPTD-COF achieves a H 2 O 2 productivity of 16.23 mmol h −1 g −1 in ethanol within 0.5 h, 16-fold higher than the unmodified terephthalic acid-based COF (PTA-COF). Ethanol acts as an efficient electron-proton donor, supplying abundant H + for the oxygen reduction reaction (ORR) and facilitating proton-coupled electron transfer (PCET) for efficient H 2 O 2 generation. This work develops a site-specific functionalization strategy to tune COF electronic structures, optimize donor-acceptor interactions, and enhanced charge dynamics, highlighting potential applications in sustainable energy and environmental remediation.
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ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Longying Zhao,Jiayu Chen,Donglin Xiang,Mierban Dawuti,Laping He,Yuangen Wu,Han Tao
Residual organophosphorus pesticides (OPs) in food pose a severe threat to public health, necessitating simple and sensitive on-site analytical methods. In this study, a signal-off electrochemical sensing platform for OPs was constructed based on the OP-induced inhibition of silver deposition triggered by red kidney bean esterase (RKBE), coupled with the signal amplification of a CuNi dual-atom catalyst (CuNi-DAC). RKBE catalyzes the hydrolysis of α-naphthyl acetate to produce α-naphthol, which reduces Ag⁺ to Ag 0 deposited on the electrode. The electroactive Ag 0 undergoes oxidation to generate a prominent oxidation current, providing a sensitive sensing signal for detection. CuNi-DAC modification of the electrode accelerates charge transfer, provides more active sites, and effectively amplifies the sensing signal. Upon exposure to OPs, the activity of RKBE is inhibited, thereby suppressing the production of α-naphthol. This leads to a diminished Ag 0 generation and subsequent a weakened oxidation current. The decrease degree of current signal shows a positive correlation with pesticide concentration. Under optimized conditions, the fabricated sensing platform exhibits a good linear response range of 10 pmol/L-1000 pmol/L for fenthion with a low detection limit of 5.4 pmol/L. Spiked recoveries in cabbage and apple samples ranged from 93.3% to 108.5%, validating the sensing platform's practicality and reliability. This work offers a facile and cost-effective electrochemical sensing approach for on-site screening of OPs.
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NEW JOURNAL OF CHEMISTRY
·
2026
·
IF 2.6
Tahseen Ahmed,Ling Zhang,Runzhi Wang,Yiling Bai,Xuehua Zhang,Yu Sun,Lili Fu,Bin Li,Menglei Yuan,Guangjin Zhang
Electrocatalytic nitrate reduction to ammonia (NO3⁻RR) provides a promising approach for converting nitrate pollutants to ammonia under mild conditions. Metal phthalocyanine-based conjugated polymers, with their well-defined structures and tunable functionality, are emerging as efficient two-dimensional (2D) catalysts for this reaction. Herein, we report a 2D-conjugated nickel phthalocyanine polymer (NiPcP) that demonstrates high efficiency and selectivity towards NO3⁻RR. The material features high-density, well-defined Ni–N4 sites and the nitrogen-bridged tetra-isoindole structures create a hydrophobic microenvironment and electron-rich Ni centers, which facilitate nitrate adsorption and electron transfer, and suppress the hydrogen evolution reaction (HER). As a result, NiPcP achieves a maximum Faradaic efficiency of 99.7% and an NH3 yield rate of 14.2 g h⁻1 gcat⁻1, maintaining over 80% efficiency across a broad potential window (from −0.5 to −0.9 V vs. RHE) and wide nitrate concentration range (from 10.0 mmol L⁻1 to 2.0 mol L⁻1). It is the first noble metal-free Ni-based catalyst that exhibits such high FE in such a broad potential window and wide nitrate concentration range simultaneously. This work offers an effective molecular design strategy for developing metal–organic electrocatalysts toward sustainable ammonia synthesis and nitrate pollution remediation.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Xinyu Fan,Jialin Guan,Yao Liu,Fengniu Lu,Jingxin Yu,Zhiqin Yuan,Hong Yan,Chao Lu
Cadmium pollution has become a globally concerning environmental issue due to its bioaccumulative propensity and potential health threats, and thus many cadmium remediation materials have been developed. However, with low cadmium concentration, partial existing remediation materials including layered double hydroxides (LDHs) show the prolonged reaction time (> 30 min) and low removal efficiency. Therefore, it is appealing to further develop ultrafast, easy-to-operate, and efficient cadmium remediation materials. In this study, we have developed an ultrafast and efficient cadmium remediation material using carbon quantum dots (CQDs) decorated calcium‑aluminum layered double hydroxides (CaAl-LDHs) via non-covalently functionalization. It is disclosed that the CQDs modification could induce the increment of calcium vacancy in LDHs layers, which reduces the cadmium adsorption energy barrier and promotes the isomorphous substitution. With such a calcium vacancy regulation strategy, the cadmium adsorption capacity showed 25.2% enhancement and the mineralization time reduced from 30 min to 30 s. This work has proposed an effective and ultrafast cadmium adsorbent by regulating the calcium vacancy and provided a promising approach to develop heavy metal remediation materials with non-covalently functionalization strategy.
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ENVIRONMENTAL RESEARCH
·
2026
·
IF 7.7
Teng Bao,Cheng long Li,Wei Wei,Mekdimu Mezemir Damtie,Zhijie Chen,Haijiao Xie,Bing-Jie Ni
Antibiotics (e.g., ofloxacin) pollution is an emerging environmental concern due to its persistence and potential health risks. Advanced oxidation processes (AOPs) offer promising solutions, yet their practical application is often limited by catalyst cost and stability. Here, we report the use of natural vivianite—a low-cost iron phosphate mineral—as an efficient peroxymonosulphate (PMS) activator for ofloxacin degradation. Under the optimised conditions, 97 % of ofloxacin was effectively degraded within 60 min. The ofloxacin degradation ratio could still reach 76 % after three consecutive cycles. Mechanistic investigations revealed Mn 2+ and Co 2+ isomorphic substitutions within the vivianite lattice, which induced electron cloud redistribution and promoted the formation of metal–oxygen–metal and metal–oxygen bonds. These structural changes enhanced charge transfer and facilitated PMS adsorption and activation via both surface-bound sites and leached phosphate species. Electron paramagnetic resonance spectroscopy confirmed that degradation proceeded through synergistic radical (·OH, SO 4 · - , O 2 · - ) and non-radical ( 1 O 2 ) pathways. Importantly, the degradation products exhibited significantly lower toxicity than ofloxacin itself, underscoring the environmental relevance of this process. These findings highlight the potential of natural vivianite as a cost-effective and sustainable PMS activator for antibiotic removal in water treatment applications.
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JOURNAL OF HAZARDOUS MATERIALS
·
2026
·
IF 10.6
Yudong Xie,Xiaowei Wang,Jinfeng Men,Min Zhu,Chengqiang Liang,Ping Bao,Biao Wang,Zeyu Guo
Efficient removal of Sr 2 + from radioactive wastewater is essential for the safe and sustainable development of nuclear power. Herein, three ferrous oxalatophosphates—(NH 4 ) 2 Fe 3 (HPO 4 ) 2 (C 2 O 4 ) 2 (NFPO), Na 2 [Fe(HPO 4 )C 2 O 4 ] (SFPO), and K 3 [Fe 4 (HPO 4 ) 2 (PO 4 )(C 2 O 4 ) 2 ]∙H 2 O (KFPO)—were synthesized via a one-step hydrothermal route and systematically evaluated for Sr 2+ capture. NFPO exhibited the best overall performance, featuring broad pH tolerance, thermal stability, and reusability. Notably, in the presence of Ca 2+ (optimal background concentration: 50 mg·L –1 ), Sr 2+ uptake was markedly enhanced, reaching equilibrium within 50 min and achieving an experimentally saturated capacity of 308.95 mg·g –1 (313 K). To improve handling and applicability, NFPO was immobilized into polyacrylonitrile microspheres (NFPO/PAN), which maintained effective dynamic adsorption in fixed-bed tests. Characterization results demonstrate that the crystalline framework remains largely preserved during adsorption, with Fe remaining in the divalent state and an ion-exchange trend involving NH 4 + . Density functional theory (DFT) calculations are further used to provide a plausible atomic-scale interpretation: Sr 2+ binding is energetically favored at oxygen-rich interfacial sites, while Ca 2+ can promote Sr 2+ capture by modulating local structure and electrostatic environment. This work highlights ferrous oxalatophosphates as promising adsorbents and provides an experimentally grounded and theoretically supported understanding for Sr 2+ remediation.
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