MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 2
·1-11
·
IF 5.3
Huang Suiyuan,Sun Xuehua,Xin Jianwei,Ma Panpan,Zhang Yuqi,Cai Zhongyu,Wang Ji-Jiang
Dexamethasone sodium phosphate (DSP) and betamethasone sodium phosphate (BSP) imprinted hydrogels embedded with two-dimensional photonic crystals (2DPC) were developed as hormones-sensitive photonic hydrogel sensors with highly sensitive, selective, anti-interference and reproducible recognition capability. The DSP/BSP molecularly imprinted photonic hydrogels (denoted as DSP-MIPH and BSP-MIPH) can specifically recognize DSP/BSP by rebinding the DSP/BET molecules to nanocavities in the hydrogel network. This recognition is enabled by the similar shape, size, and binding sites of the nanocavities to the target molecules. The rebinding of hormones molecules causes the hydrogel to swell, resulting in a particle spacing increase of the embedded 2DPC of the hydrogel. The particle spacing increase can be used as sensing signal and can be acquired by simply measuring the Debye diffraction diameters of the photonic hydrogel sensor before and after exposure with a laser pointer and a ruler. The particle spacing increments of the DSP-MIPH and BSP-MIPH sensors linearly change when DSP and BSP concentrations changes within the ranges 0.025–1 μM, 10–100 μM, and 100–500 μM, and the limits of detection (LoD) are 21.8 nM for DSP and 12.6 nM for BSP, respectively. These photonic hydrogel sensors were successfully applied to the determination of DSP/BSP contents in the real pharmaceutical injections, providing an ideal strategy for the development of portable hormones sensors. Graphical
研究领域:
材料科学
·
分析化学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
Journal of Central South University
·
2024
·Vol. 31
·期 3
·796-812
·
IF 3.7
Guan Zhi-wen,Jiao Fen,Wang Xu,Qin Wen-qing,Fu Li-wen,Zhang Zheng-quan,Li Wei
In this paper, the inhibition ability of tetrasodium pyrophosphate (TSPP), sodium tripolyphosphate (STPP) and sodium hexametaphosphate (SHMP) to scheelite, fluorite and calcite was predicted by performance calculation and further verified by micro-flotation test. The results of hydrophile lipophilic balance (HLB) calculation, group electronegative calculation and micro-flotation test indicated that the inhibition ability of phosphate to the three minerals increases with the increase of the number of phosphate groups and the order of inhibition ability of the three inorganic phosphates was SHMP > STPP > TSPP. STPP had great potential for flotation separation of scheelite from fluorite and calcite. The order of inhibition ability of STPP against the three calcium-bearing minerals is calcite>fluorite>scheelite. The results of contact angle measurement, adsorption amount measurement, X-ray photoelectron spectroscopy (XPS) analysis and atomic force microscope (AFM) imaging presented that the adsorption of STPP on the fluorite and calcite surface was much larger than that on the scheelite surface. The weak adsorption of STPP on the scheelite hardly influenced the collection of sodium oleate (NaOL). STPP could complex with Ca 2+ on the surface of fluorite and calcite, and hinder the subsequent adsorption of NaOL. The results can provide guiding significance for the flotation of scheelite and the screening of inhibitors for calcium-bearing gangue minerals.
研究领域:
矿物加工工程
·
化学工程与技术
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DOI
高影响因子
Minerals
·
2018
·Vol. 8
·期 7
·278
·
IF 1.835
Yanfei Chen,Qiming Feng,Guofan Zhang,Dezhi Liu,Runzhe Liu
In this study, the effect of sodium pyrophosphate (NaPP) on the separation of apatite from dolomite by flotation was systematically investigated. Flotation results revealed that NaPP could selectively depress the flotation of apatite, thus realizing the separation of apatite from dolomite. Further, the selective depression mechanism of NaPP was studied through zeta potential measurements, contact angle measurements, and X-ray photoelectron spectroscopy (XPS) analysis. The results demonstrated that the adsorption of sodium oleate (NaOL) onto apatite surface was depressed by the preferential interaction of NaPP with active Ca sites. For dolomite, while the presence of NaPP hindered the interaction of NaOL with active Ca sites, it appeared to enhance the reactivity with active Mg sites. Thus, the adsorption of NaOL onto dolomite surface was hardly influenced. In this way, the separation of apatite from dolomite was achieved.Keywords:sodium pyrophosphate;flotation;depression;apatite;dolomite
研究领域:
矿物加工工程
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化学工程
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产品关联
DOI
高影响因子
Minerals
·
2023
·Vol. 13
·期 4
·457
·
IF 2.5
Chenyu Fan,Liuyi Ren,Yimin Zhang,Shenxu Bao,Zhilu Yang
In this paper, different doses of sodium hexametaphosphate (SHMP) were added as grinding aids in the process of muscovite grinding, and the effect of SHMP on the grinding efficiency of muscovite was studied. The grinding experiment results show that the grinding efficiency increases significantly with the increase in SHMP dosage. The mechanism of SHMP improving the grinding efficiency of muscovite was analyzed by various test methods. Experimental results showed that when SHMP was used as a grinding aid, the ordered structure of muscovite crystals was destroyed, the surface of muscovite was roughened, and obvious cracks appeared. SHMP was physically adsorbed on the muscovite powder, which effectively improved the pulp environment of muscovite powder during grinding, resulting in more dispersed muscovite powder, and improved the grinding efficiency. This study provides theoretical guidance for the efficient preparation of fine-grained muscovite powder and the action mechanism of grinding aids.Keywords:grinding aids;muscovite;sodium hexametaphosphate;pulp dispersibility
研究领域:
矿物加工工程
·
材料科学与工程
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DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Li Wang,Lingfeng Shen,Wei Sun,Xiangfeng Zhang,Ye Zhang,Yanhong Wang
In this study, a depressant sodium hexametaphosphate (SHMP) was introduced for the flotation separation of smithsonite from dolomite using mixed benzohydroxamic acid (BHA) and sodium oleate (NaOL) as the collectors. Micro-flotation experiments were conducted to investigate the flotation behavior of smithsonite and dolomite in the absence and presence of SHMP. Furthermore, the depression mechanism of the SHMP was unraveled by Fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS) analysis, and flotation solution chemistry . The flotation results showed that the recovery of dolomite decreased from 26.63% to 2.25% when the addition of SHMP in the flotation system increased from 0 to 50 g/t, while the smithsonite recovery exhibited a slight increase from 91.05% to 93.10%, which improved the separation effect greatly. FTIR measurements and XPS analysis revealed that the SHMP was chemically adsorbed on the dolomite surface in the form of hydrophilic complexes with Ca 2+ and Mg 2+ , thus depressing adsorption of the mixed BHA/NaOL. Flotation solution chemistry analysis suggested that Zn 2+ could form ZnCO 3 on the surface of the dolomite leading to the transformation of the dolomite surface to the smithsonite surface. And SHMP could form hydrophilic complexes with Ca and Mg sites on the dolomite surface, thus depressing the adsorption of BHA/NaOL on the transformed dolomite surface.
研究领域:
矿物加工工程
·
表面化学
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产品关联
DOI
高影响因子
Journal of Magnesium and Alloys
·
2022
·
IF 11.813
Shupei Liu,Xinfang Zhang,Chijia Wang,Changqing Yin,Jinsong Rao,Yuxin Zhang,Dusan Losic
Integrating different active substances through carriers and fully exerting their synergistic corrosion inhibition ability is an efficient anticorrosion strategy. Biotemplate (diatomite) was used to integrate polyaniline and sodium phosphate, an active antiseptic filler (PANI/DM/SP) was prepared in this work. Moreover, active fillers were combined with epoxy resins to prepare high-efficiency anti-corrosion coatings for magnesium alloy protection. The stability of the corrosion inhibitor (sodium phosphate) released by the active filler was analyzed by establishing a mathematical model. Simultaneously, electrochemical impedance spectroscopy tests demonstrate excellent corrosion inhibition properties of active fillers and the impedance modulus of composite coatings was three orders of magnitude higher than that of the EP coating, due to the synergistic effect of each component of the active filler. In addition, the mechanical properties of the composite coating were significantly improved, with tests showing a 51.31% increase in rub resistance and two grades of adhesion improvement (ASTM standard). The key of this work was to give full play to the slow-release characteristics of diatomite through scientific methods and promote the synergistic anticorrosion effect of sodium phosphate and polyaniline.
研究领域:
材料科学
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腐蚀与防护
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纳米技术
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产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Cunli Pan,Junqing Qian,Changyan Zhao,Haiyang Yang,Xiaohua Zhao,Hui Guo
In order to reveal the relationship between the degree of crosslinking and the properties of chitosan nanoparticles, a potassium polyvinyl sulfate (PVSK) titration method was established for the determination of free amino group in chitosan, which showed that there was a window effect in the crosslinking degree and particle size of three kinds of molecular weight chitosan cross-linked by different content of tripolyphosphate (TPP), and the nanoparticles with moderate crosslinking degree were smaller. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) showed the moderate degree of cross-linking nanoparticles had strong antibacterial properties. IR analysis showed that the interaction between chitosan nanoparticles with different crosslinking degree and TPP were different. X-ray diffraction analysis showed that the cross-linked chitosan nanoparticles were amorphous. Above all, the crosslinking degree of TPP cross-linked chitosan nanoparticles was related to the particle size and antibacterial properties.
研究领域:
生物材料学
·
药剂学
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产品关联
DOI
PubMed
高影响因子
MINERALS ENGINEERING
·
2019
·
IF 3.315
Cheng Liu,Shaoxian Song,Hongqiang Li
In this paper, trisodium phosphate (TSP) was utilized for the flotation separation of fluorite from barite. Micro-flotation results showed that good floatability of both fluorite and barite was obtained at around pH 8.5 using sodium oleate (NaOL) as a collector. TSP showed a selective depression for barite, and flotation separation of fluorite from barite was achieved using TSP as a depressant and NaOL as a collector. Zeta potential measurements indicated that the addition of TSP prior to NaOL did not prevent the adsorption of NaOL on fluorite surface while it prevented NaOL to adsorb on barite surface.
研究领域:
矿物加工工程
·
化学工程
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2012
·
IF 2.098
Lun Wang,Fei Yuan,Hong-Qi Chen,Bo Ling,Juan Xu
A novel flow injection nanocrystals (NCs) chemiluminescence (CL) analysis method has been established for the determination of estradiol, estriol and estrone based on the enhancement of CdTe NCs–KMnO 4 CL reaction catalyzed by sodium hexametaphosphate. Glutathione (GSH)-capped CdTe nanocrystals were synthesized in aqueous medium, and the CdTe NCs emitted at around 555 nm was selected as the light emitter in CdTe NCs–KMnO 4 chemiluminescence (CL) system. It has been found that sodium hexametaphosphate (SHMP) enhanced the CL of the CdTe NCs–KMnO 4 system and estrogens increased these CL signals again in near neutral solution. UV–visible spectra, photoluminescence (PL) spectra, transmission electron microscopy (TEM) and CL spectra were used to characterize CdTe nanoparticles and investigate the mechanism of the CL reaction. On the basis of the enhancement, a novel flow-injection CL method has been established for the determination of estrogens. Under the optimum experimental conditions, three linear relationships were obtained. The method described is simple, sensitive, and has been successfully utilized for the determination of estrogens in tap water samples.
研究领域:
分析化学
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环境科学
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生物医学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Xin Gao,Siyi Huang,Guozhi Zhao,Qian Cui,Xingyu Wen,Zimeng Zhu,Mengyao Liu,Huajiang Zhang,Yujie Chi
This study investigated the changes in the gel properties and physicochemical indexes of whole egg liquid produced by the combined addition of sodium pyrophosphate (TSPP) and gellan gum (GG) at different concentrations and analyzed the underlying mechanisms. Results showed that the addition of TSPP and GG synergistically increased the hardness, springiness, chewiness, and water holding capacity (WHC) of the whole egg liquid gel. When the concentrations of both TSPP and GG were 0.2 %, the whole egg liquid gel exhibited superior properties, with hardness, chewiness, and WHC increasing by 59.92 %, 59.68 %, and 8.15 %, respectively, compared with those of the untreated whole egg liquid gel. Scanning electron microscopy results showed that the addition of GG resulted in a clear filamentous and reticulated structure within the whole egg liquid gel. In terms of physicochemical properties, the addition of TSPP increased the absolute value of zeta potential of the whole egg liquid, and the co-addition of GG had little effect on the zeta potential. However, compared to adding only TSPP, the addition of GG increased the average particle size, apparent viscosity, G′ and G" of whole egg liquid.The changes in surface hydrophobicity of the whole egg liquid displayed a similar trend to that of the gel hardness.
研究领域:
食品科学
·
生物化学
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产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2017
·
IF 4.811
Jie Wu,Yaping Wang,Hao Yang,Xiangyu Liu,Zhong Lu
Nanoparticles with size range of 10–500 nm can be efficiently delivered into cancer cells by the Enhanced Permeability and Retention (EPR) effect. Here, we prepared resveratrol (Res) loaded chitosan (CS) nanoparticles with the size of 172–217 nm by an ionic cross-linking method, with sodium tripolyphosphate (TPP) as the cross-linking agent, to improve the stability, solubility and tumors targeting of the natural anti-cancer drug Res. The prepared Res loaded CS-TPP nanoparticles presented long-term storage stability and UV light stability. The cumulative drug release from nanoparticles in mimetic tumor tissue condition (pH 6.5) was higher than that in physiological condition (pH 7.4). Further, Res-loaded CS-TPP nanoparticles maintained the antioxidant activity of Res even after UV light irradiation. Cell viability study shows that the as prepared drug loaded nanoparticles had similar antiproliferative activity on hepatocellular carcinoma cells SMMC 7721 and lower cytotoxicity on normal hepatocyte cells L02 compared with free Res. Fluorescence microscopy observation revealed that the nanoparticles were efficiently taken in by SMMC 7721 cells. This work indicates the potential use of drug loaded CS-TPP nanoparticles for the efficient delivery of bioactive Res for chemotherapy.
研究领域:
药剂学
·
肿瘤学
·
生物材料学
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2015
·Vol. 4
·期 6
·1116-1121
·
IF 4.726
Jun Zhang,Zhijun Sun,Haomiao Zhu,Qiaochu Guo,Chengai He,Ao Xia,Hong Mo,Xiaohua Huang,Jian Shen
Improving hemocompatibility of biomaterials and devices contacting the human blood has been the subject of intensive research. In this study, we synthesized a novel excellent blood compatible polyurethane/sodium triphosphate nanoparticle (PU/STPP). Characterization of polyurethane/sodium triphosphate (PU/STPP) nanoparticles was carried out by transmission electron microscopy (TEM), scanning electron microscopy (SEM), dynamic light scattering (DLS), nuclear magnetic resonance (NMR), and energy dispersive spectroscopy (EDS). Blood compatibility assessment of PU/STPP nanoparticles was performed by in vitro coagulation time, plasma clotting time, hemolysis rate, and red blood cell morphology tests. Cell compatibility evaluations of PU/STPP nanoparticles were obtained by MTT cell viability tests. The PU/STPP nanoparticles also were used to modify vascular prostheses with cosedimentation. Platelet adhesion tests showed that blood compatibility of vascular prostheses coated with PU/STPP nanoparticles is better than that of pure vascular prostheses.
研究领域:
生物材料
·
医学工程
·
血液学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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