SEPARATION AND PURIFICATION TECHNOLOGY
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2018
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IF 3.927
Junlian Wang,Xinyu Liu,Jiashuai Fu,Meiying Xie,Guoyong Huang,Huajun Wang
Scientists have always been seeking more efficient extractants for rare earths extraction and separation, especially for heavy rare earths. In this paper, a novel extractant (2,4-dimethylheptyl)(2,4,4′-trimethylpentyl)phosphinic acid (USTB-2) was synthesized. The structures of the intermediate and USTB-2 were characterized by 31 P NMR, 1 H NMR, FT-IR and ESI-MS. Its p K a was 5.62. Its extraction ability was between Cyanex 272 and P507. Its extraction mechanism was cation exchange. Its extraction capacity was larger than that of Cyanex 272 and lower than that of P507. Its solubility in 3 mol/L HCl and deionized water was 11.2 mg/L and 19.0 mg/L, respectively. The Lu(III) loaded in USTB-2 solution can be easily stripped by HCl, HNO 3 and H 2 SO 4 . It has good separation performance for heavy rare earths. Its average separation factor ( β ¯ ) for adjacent heavy REs from Gd to Lu was 2.18. For some heavy RE couples like Er/Ho, Yb/Tm and Lu/Yb (especially for Lu/Yb), USTB-2 possesses even better separation performance than Cyanex 272. Its extraction efficiency for nonferrous metal ions was in the order Al > Gd > Zn > Nd > La > Co > Cu. The separation factors of Al/Gd, Gd/Zn, Zn/Nd, La/Co by USTB-2 were 2.67, 5.39, 3.35 and 26.67, respectively.
研究领域:
化学
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材料科学
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2017
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IF 3.359
Junlian Wang,Meiying Xie,Xinyu Liu,Huajun Wang
By combining the structures of P227 and Cyanex 272, a nonsymmetric dialkylphosphinic acid USTB-1 was synthesized. Its structure was confirmed by 31 P NMR, 1 H NMR, MS and IR. Its pK a and purity were determined through potentiometric titration method. Its extraction and separation performance for RE(III) were studied. The purity of USTB-1 was 97.6%. Its pK a was 5.73, which was very close to that of P227 and Cyanex 272. Its solubility in deionized water was 34.7 mg/L. Its extraction ability was equal to that of P227 and Cyanex 272. It can reach extraction equilibrium as fast as Cyanex 272. Its complex with Lu(III) has larger solubility in n -octane than that of Cyanex 272, which indicated that USTB-1 has higher extraction capacity than Cyanex 272. The Lu(III) loaded in USTB-1 solution can be stripped by HCl as easily as the Lu(III) loaded in P227 and Cyanex 272 solutions. USTB-1 has good separation performance for RE(III), especially for heavy RE(III). Its average separation factor of adjacent heavy RE(III) from Ho to Lu was 2.21, superior to Cyanex 272 ( β N + 1 / N ‾ from Ho to Lu: 2.08).
研究领域:
化学
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材料科学
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DOI
高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
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2018
·Vol. 87
·期 2
·442-454
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IF 1.745
Xiong Chao,Wang Shixing,Zhang Libo,Li Ying,Srinivasakannan Chandrasekar,Peng Jinhui
Abstract A novel adsorbent was synthesized by functionalizing nanosilica with phosphinic acid groups for the removal of mercury ions from aqueous solutions. The synthesized absorbent was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), transmission electron microscope (TEM) and thermogravimetric analysis (TGA). Meanwhile, the effects of initial pH, contact time and initial mercury ions concentration on the removal of mercury ions from aqueous solutions were investigated by batch adsorption experiments. The results showed that the removal rate reached 99.11% and the maximum adsorption capacity was up to 274.32 mg/g at pH 2 and the equilibrium time of adsorption was about 1 h. The absorbent presented good selectivity for mercury ions among Zn(II), Ni(II), Mn(II) and Ge(IIII). Moreover, the obtained adsorbent has good reusability and the absorbability decreased only from 98.76 to 94.75% after five cycles. Besides, the adsorption isotherms fitted well to the Langmuir isotherm model and adsorption kinetics followed the pseudo-second-order model. The removal mechanism of mercury via phosphinic acid-functionalized silica nanoparticles was chelation interaction. All the experimental data indicated that the phosphinic acid-functionalized silica nanoparticles are very promising in removal of mercury ions from aqueous solutions.
A novel adsorbent was synthesized by functionalizing nanosilica with phosphinic acid groups for the removal of mercury ions from aqueous solutions. The adsorbent presented good selectivity and reusability. The removal mechanism is chelation interaction between mercury ions and PA-SNPs.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
HYDROMETALLURGY
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2013
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IF 2.169
Junlian Wang,Shengming Xu,Linyan Li,Jing Li
Efficient new extractant design relies on systematic structure–property studies. However, systematic structure–property research on extractants of organic phosphinic acids is far from sufficient. To make up for this deficiency, twelve organic phosphinic acid extractants (including nine dialkylphosphinic acids, two dicycloalkylphosphinic acids and one diarylphosphinic acid) were synthesized with free-radical-addition-reaction method and Grignard-reaction method. Reaction rules, advantages and disadvantages of these two methods were discussed respectively. The extraction ability and separation performance of the synthesized organic phosphinic acids for Tm, Yb and Lu from HNO 3 solutions were evaluated and compared. For dialkylphosphinic acids the nearer the branched chain moved to P atom, the more reduction generated on the extraction ability. Dialkylphosphinic acids without branched chain in α-C or β-C (e.g. HYY-3, HYY-5, HYY-7 and HYY-9) exhibited strong extraction ability as P507. On the contrary, dialkylphosphinic acids with branched chain in α-C (e.g. HYY-4, HYY-8) and dicyclohexylphosphinic acids exhibited poor extraction ability as Cyanex 272. New compound Di-(2,3-dimethylbutyl)-phosphinic acid (HYY-2) exhibited good extraction ability and separation performance and its separation factors of Lu/Yb, Yb/Tm and Lu/Tm were 1.42, 3.10 and 4.40 respectively, apparently superior to Cyanex 272 (β Lu/Yb = 1.31, β Yb/Tm = 3.25, β Lu/Tm = 4.26).
研究领域:
化学
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材料科学
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DOI
高影响因子
ACS Omega
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2024
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IF 3.7
Komal Hayat,Gemma Nixon,Qian Zhang,Magdalini Matziari
A highly efficient method to synthesize diverse symmetrical phosphinic acids with the potential to act as pivotal candidates in the design of HIV-1 protease inhibitors has been developed. Such compounds have been designed based on the enzyme–substrate specificity, and their elongated analogues are expected to demonstrate significant inhibition against the HIV-1 protease with IC50 values in the low nanomolar range. Moreover, a highly efficient esterification protocol with carbohydrates and flavonoids has been devised to address the inherent absorption challenges associated with phosphinic-based drugs. These esters not only exhibit low toxicity but also have the potential to generate flavonoid moieties in situ, which are associated with hepatoprotective effects, or naturally occurring carbohydrate metabolites. The methodology utilizes effective peptide coupling reagents, such as aminium-based TBTU and carbodiimide-based DIC, and affords the target products in excellent to quantitative yields. This research represents a promising avenue for the development of novel HIV-1 protease inhibitors with significant therapeutic benefits.
研究领域:
药物化学
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生物化学
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抗病毒研究
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DOI
PubMed
高影响因子
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