TETRAHEDRON LETTERS
·
2020
·
IF 2.275
Haibo Zhu,Yingying Zhang,Yishuai Liu,Liu Yang,Zongbo Xie,Guofang Jiang,Zhang-Gao Le
A practical and efficient approach adopting transition-metal-free cross-coupling of sulfonyl hydrazides with benzyl ammonium salts has been developed to synthesize benzyl sulfones using Cs 2 CO 3 as base under mild conditions. The protocol employs stable and easy to handle coupling partners, and is endowed with good substrate compatibility, leading to functional benzyl sulfones in good yields.
研究领域:
有机化学
·
合成化学
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产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 139
·期 39
·e52943
·
IF 3.057
Congyang Ma,Sheng Wang,Yage Li,Tianjia Yu,Youwei Yao,Hongda Du,Qiang Cai
Generally, foamed epoxy resin prepared by chemical method has relatively large average cell size and low cell density, resulting in low mechanical properties and poor heat resistance. In this work, a new type of composite foaming agent (CFA) was prepared by filling the chemical foaming agent 4,4′-bisoxybenzenesulfonyl hydrazide (OBSH) into microporous silica microspheres (MSMs), and then used for epoxy resin foaming research. The effects of curing agent diethylenetriamine (DETA) and CFA contents on cell density and size were also discussed. The best epoxy resin foaming sample has a cell density of 10 6 cells cm −3 with an average cell diameter of 65 μm, and a high compressive strength of 34 MPa as well as a good heat resistance. These results indicate the potential application of CFA in epoxy resin foaming area.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2015
·Vol. 132
·期 47
·
IF 1.768
Yi-Fan Zhang,Xiao-Jun Wang,Zhi-Gang Pan,Cheng-Ming Hong,Gao-Feng Ji
The activation of foaming agent is critical to its application. In this study, 4,4′-oxibis-(benzenesulfonyl hydrazide) (OBSH) activated by urea was used in the manufacture of low-density unsaturated polyester resin (LDUPR), and the results were compared with that of OBSH activated by zinc oxide and zinc stearate. The experiment results showed that the activation of OBSH by urea was better than by zinc oxide or by zinc stearate. A novel hydrogen bond activation mechanism of urea is presented in this research. Two stages, including the induction stage and the foaming stage, were proposed in the LDUPR manufacture according to the gas evolution curves of activated OBSH. The decomposition temperature and the decomposition time of OBSH activated by urea were determined to match the gelation time of UPR for the manufacture of LDUPR. The disadvantageous chemical behaviors of activated OBSH were eliminated in the induction treatment. The activated OBSH via induction treatment released gas maximally and distributed gas homogeneously in the resin glue, resulting in a better foaming effect than that of the previous foaming agents. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 42824.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
ANALYST
·
2013
·Vol. 138
·期 18
·5344-5356
·
IF 3.969
Chengjian Wang,Jiangbei Yuan,Xiaohua Li,Zhongfu Wang,Linjuan Huang
Qualitative and quantitative studies of glycosylation patterns of various biologically important proteins represent a key field for the understanding of their complex structure–function relationships. However, the analysis of glycoprotein glycans is usually undermined by tedious sample processing steps prior to detection, including deproteination, desalting and removal of some other non-glycan impurities, which results in considerable sample loss and increased difficulty of quantitative analysis. Herein we report a facile and versatile method for the quantitative isolation of reducing glycans from complex samples using sulfonyl hydrazine-functionalized polystyrene (SHPS) beads, namely the SHPS-based glycan capturing procedure. This method allows the chemoselective and efficient condensation of the aldehyde group of reducing glycans with the active sulfonyl hydrazine group of SHPS beads under anhydrous conditions, resulting in the formation of sulfonyl hydrazone conjugates. The non-glycan components in samples, such as proteins, salts and some other impurities, can be completely removed by washing the sulfonyl hydrazone conjugates. Regeneration of the reducing glycans can be performed via mild hydrolysis of the washed sulfonyl hydrazone conjugates. This procedure is compatible with almost all the current techniques for the derivatization or detection of reducing glycans. We have obtained essential data for this method, including optimized reaction conditions, linearity and reproducibility for glycan quantitation, as well as a final glycan recovery ratio. Moreover, mass spectrometric analysis of the glycans from some complex biological samples, including milk, human blood plasma and fetal bovine serum, was achieved, demonstrating good applicability of this novel procedure.
研究领域:
生物化学
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蛋白质组学
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分析化学
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产品关联
DOI
PubMed
高影响因子
SYNTHESIS-STUTTGART
·
2022
·Vol. 54
·期 11
·2707-2723
·
IF 2.969
Jiahui Fu,Xingxing Cai,Yihuo Liu,Jinghua Li,Dongping Cheng,Xiaoliang Xu
An efficient visible-light-mediated tandem reaction of acryloylbenzamides with alkylboronic acids, arylsulfonyl hydrazides and oxime esters has been developed. The reaction proceeds via radical addition and cyclization to give various isoquinoline-1,3(2H,4H)-diones in satisfactory yields under mild conditions, which provides a good opportunity to discover new meaningful bioactive compounds.
研究领域:
有机化学
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光化学
·
合成化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）