SENSORS AND ACTUATORS B-CHEMICAL
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2022
·
IF 9.221
Ke Ning,Huihui Chai,Yanxia Cui,Shiming Wu,Feng Chen,Yuan Li,Ping Qiu,Wei Sun,Ling Yu
Elevating blood ß 2 microglobulins (ß 2 M) level is one of the indicators of diseases such as diabetes, kidney failure, and tumors. A centrifugal microfluidic chip was designed to conduct latex immunoagglutination assays for testing ß 2 M. A handhold centrifuge was assembled to drive solution mixing in the microfluidic chip. An office scanner recorded the binding of ß 2 M to the latex beads induced agglutination, reducing reliance on expensive scientific equipment and avoiding environmental light interference. The results revealed that the degree of beads agglutination was proportional to the grayscale value changes (∆G). The ß 2 M testing can be accomplished using a 1.25 µL blood sample, and the testing time is 10 min. The limit of detection is 0.0335 mg/L. The recovery rate calculated by the measured and spiked ß 2 M concentration ratio is 91.8–111.8%. The centrifugal chip was applied to test 50 patients’ samples. The confusion matrix analyzed the rate of false positives, false negatives , true positives, and true negatives for the ß 2 M chip-based test, showing the sensitivity of the ß 2 M chip is 77.3%, the specificity is 82.1%, and the efficiency is 80%. The Area Under the Curve analysis shows that the cutoff value (∆G = 1.011) of ∆G in predicting ß 2 M elevating has a sensitivity of 100% (95% CI: 92.87% −100%) with the specificity of 92% (95% CI:81.6–96.85%).
研究领域:
医学诊断
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生物医学工程
·
临床检验
✓ 已验证
DOI
高影响因子
CARBOHYDRATE POLYMERS
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2015
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IF 4.074
Xianglong Li,Huanhuan Chen,Bin Yang
Centrifugal spinning and electrospinning have proved to be effective techniques for fabricating micro-to-nanofibers. However, starches of amylopectin content above 65% cannot be fabricated to fiber by electrospinning. This paper is focus on the centrifugal spinnability of amylopectin rich starches. We investigated the amylopectin content of starches by Dual-wavelength colorimetry, studied the rheological properties of starch dopes to determine entanglement concentration ( c e ) by rotary rheometer. Results indicated that amylopectin rich native corn and potato starches, which with amylopectin content higher than 65%, were suitable for centrifugal spinning to micro-to-nanofibers. Additionally, starch-based fibers were successfully fabricated from the amylose rich corn starch as well. Rheological studies showed that the entanglement concentration ( c e ) of starch solution was crucial for successful centrifugal spinning.
研究领域:
材料科学
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食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 135
·期 6
·45810
·
IF 1.86
Xianglong Li,Teng Hou,Yishen Lu,Bin Yang
In the present study, we provide a method for controlling the surface morphology of centrifugally spun starch-based fibers by adjusting the ratio of amylopectin/amylose in starches and combining with a hot blast temperature. The effects of hot blast temperature, amylopectin, and amylose on fiber surface morphologies are investigated. Scanning electron microscopy is used to characterize the morphology of the prepared fibers. The results show that fibers with burr-shaped nanostructures on the surface can be fabricated by adding amylopectin to starches and are promoted by increasing the hot blast temperature. However, amylose in starches plays the role of smoothing the fiber surfaces. X-ray diffraction reveals that the fibers are amorphous. Through Fourier transform infrared spectroscopy analysis, it was found that some physicochemical changes occur during centrifugal spinning. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 45810.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
Lubricants
·
2022
·Vol. 10
·期 9
·226
·
IF 3.584
Cunao Feng,Yujie Zhao,Tao Zhang,Kai Chen,Xiaowei Li,Dekun Zhang
Aseptic loosening caused by the wear and tear of the artificial joint prosthesis after implantation is one of the main causes of artificial joint failure. Therefore, it is important to investigate the wear debris generated due to wear when developing new artificial joint materials. Aseptic loosening is related to the size, number, and morphology of wear debris, and this study proposed the separation and extraction of mixed wear debris with different density ratios of artificial joints by centrifugation to study the characteristics of different artificial joint wear and wear debris extraction rates. The results showed that multiple centrifugations to separate the mixed wear debris were able to reintroduce the wear debris on the wall of the centrifuge tube into the solution and that the wear debris extraction rate was increased. Suspensions with different density ratios of artificially jointed mixed wear debris were effectively separated by this method. The total extraction rate of the three repeated extractions compared to the first extraction rate, the extraction rate of CoCrMo wear debris increased by 6.7%, ultra-high molecular weight polyethylene (UHMWPE) wear debris increased by 15.1–23.44%, ZrO2wear debris increased by 10.91%, and that of polyether ether ketone (PEEK) wear debris increased by 9.95%. This method for separating and extracting wear debris from artificial joints can realize the separation of mixed wear debris from artificial joints and obtain a high extraction rate and high-quality wear debris images, investigate the wear mechanism of artificial joint implants, and provide valuable information on the wear performance of new artificial joint implants under investigation.Keywords:different density ratios;multiple centrifugal separations;wear chips
研究领域:
生物医学工程
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 2
·346
·
IF 5.3
Wenning Zhao,Fan Lin,Xiuxun Han
The replication of nano-patterns is a significant means of nanomanufacturing. However, there is still a dearth of nano-replication methods that meet the requirements of both high precision and low cost. Therefore, a new strategy to achieve the replication of nano-patterns, namely centrifugal-force-driven nano-replication (CFDNR), is proposed here. An easily obtained centrifugal force which is perpendicular to the plane of a nanostructured template is designed as a driving power, to compel the dynamic polymer to fully fill the space of the template; then, the nano-pattern can be replicated on a polymer film. Anodic aluminum oxide (AAO) templates with nanohole periods of ~450 nm and ~100 nm were employed as the original masters to investigate the nano-replication behaviors. The results of morphology measurements demonstrate excellent precision. The size deviations between the nanohole in the template and the nanopillar on the polymer film are less than 4%. Furthermore, a vacuum-assisted CFDNR scheme is proposed to prevent the formation of cavitation on the polymer replica. This work provides new possibilities and choices for facile, inexpensive and high-precision nanomanufacturing.Keywords:nano-replication;centrifugal force;polymer;anodic aluminum oxide
研究领域:
纳米制造
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Yifan Li,Weichun Pan,Zhihui Feng,Feina Gu,Jianxin Chen,Fang Wang,Jieqiong Wang,Mingming Zhang,Chunmei Li,David Julian McClements,Junfeng Yin
Keemun tea infusion was selected as a model system under various centrifugation speeds to build a relationship among chemical composition, properties of nanoparticles in tea infusion (Tea-NPs), and tea tastes via chemical analyses, sensory evaluation, and light scattering techniques. The research results showed that the hydrodynamic radius ( R h ) of the Tea-NPs in the black tea infusion ranged from 100 to 250 nm, with a negative charge (-10 to -13 mV). The gyration radius ( R g ) and zeta-potential assessments elucidated that Tea-NPs underwent structural modifications, which altered their size, shape, and compactness. High-speed centrifugation caused the dissolution of components such as polysaccharides in the Tea-NPs, and changes in the particle compactness and aggregation altered the structure of the Tea-NPs, resulting in an increase in R h , while reducing the bitterness and enhancing the overall flavor of the tea infusion. This study highlights the important role of Tea-NPs in tea quality evaluation and their potential to drive innovative methods for improving tea product quality.
研究领域:
食品科学
·
茶学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Analytical Methods in Chemistry
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2022
·
IF 2.594
Zhen Pan,Xiaozhan Nong,Yajing Xie,Yan Li,Hui Zeng,Ying Liang,Min Zhang
Phosphate concentration in natural water has been used as a water quality indicator, as it is one of the major nutrients for aquatic plants. However, the traditional phosphomolybdenum blue (PMB) method has limited sensitivity for visual or camera-based detection, leading to underestimation of the phosphate concentration. We present an ultralow-cost, rapid field preconcentration and digital image colorimetric sensing of low-concentration phosphate method for water analysis. A novel hand-powered paper centrifuge (paperfuge) is used for sample preparation and preconcentration. This paperfuge is made of two circular paper discs and a string. Six centrifuge tubes (CTs) originally used as glue dispensing tips with a sample capacity of ∼230 μL, are loaded on the paperfuge. After sampling, phosphate in the water sample is reacted to form PMB. Then, the reacted sample is drawn into a CT using an autopipette before the CT bottom is sealed by glue. After Oasis® HLB sorbents are added through the top of the CT, the CT top is also sealed with glue. The HLB sorbents adsorb PMB and are accumulated in the CT tip through centrifugation. The CT tips are cut and analyzed with the ImageJ software. It was found that the blue color intensity of sorbents is in a linear relationship to the phosphate concentration, with a linear range of 0–5 μM (r2 = 0.9921) and limit of detection of 0.19 μM. In addition, this method has been applied to in-field water analysis. The results are in agreement with the standard PMB method.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
WATER RESEARCH
·
2021
·
IF 11.236
Huiwen Cai,Mengdi Chen,Fangni Du,Sara Matthews,Huahong Shi
Nanoplastics are an emerging contaminant in aquatic environments. However, analytical methods for the separation, concentration, and identification of nanoplastics, which are essential to assess nanoplastic presence in the environment, are lacking. Here, we developed a new and easy-to-use method to separate and enrich nanoplastics in field water samples with ultracentrifugation. River water was spiked with polystyrene fragments (< 1000 nm) at an environmentally relevant concentration (10 8 –10 9 particles/L). The polystyrene fragments were successfully separated and enriched by a factor of nearly 50 times with a high recovery rate (87.1%) after undergoing our process. Particles were then characterized using UV-vis spectroscopy, scanning electron microscopy (SEM), and enhanced darkfield microscopy with a hyperspectral imaging (HSI) spectrometer. These techniques are non-destructive and allow the assessment of plastic concentration, morphology, and polymer type. Our method can potentially be applied to other water samples to supply clean, enriched nanoplastic samples that can facilitate their identification in environmental samples.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2020
·
IF 4.551
Xinchao Liu,Jing Wang,Yongde Xia,Xinhuan Lu,Qinghua Xia,Dan Zhou
From the considering of simple synthesis step, low cost, and energy saving, one-step synthesis of hierarchical zeolite without involving additional template has obvious advantages compared with post-synthetic modification or one-step templating methods, by which Ti-containing hollownest structure zeolite (Ti-HSZ) has been successfully synthesized. Herein, the origin of Ti-HSZʼs hollownest structure has been investigated by systematical comparison study between the rotating hydrothermal (RH) and static hydrothermal (SH) synthesis routes. It is found that different synthesis routes not only influence the crystallization but also determine the chemical and physical properties of zeolites. Compared with the catalyst prepared by flower-like precursor with larger size obtained by SH route in 12 days, Ti-HSZ catalyst with smaller size formed by RH route in 3.5 days shows higher catalytic activity for the epoxidation of bulky alkenes with H 2 O 2 . On one hand, the rapid and efficient transports of various reaction species in RH environment has accelerated the crystallization rate greatly; on the other hand, the one-step self-assembly of lamellar MWW crystals has happened to facilitate the formation of hollownest structure with hierarchical pores through intergrowth driven by centrifugal force. The different evolution processes of the Si chemical environments during the early stages of crystallization reflected by the percentage of intrinsic defects origin from the different hydrothermal environments. Highly mixed and dispersed reaction species under RH condition accelerate the uniform of gel concentration, and the condensation of smaller clusters with different orientation direction through frequent contacting under dynamic condition is easy to happen to form bigger clusters, which is the basis for the further crystal intergrowth. In contrast, the relatively inhomogeneous gel environments under SH condition has led to the increase of intrinsic defects in the solid phases, and bigger clusters tend to be formed by the condensation of smaller ones with the same orientation direction. This work will be instructive not only for the understanding of zeolites’ crystallization mechanism, but also for the design and synthesis of zeolite materials with unique morphology characteristics.
研究领域:
材料科学
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2018
·
IF 3.927
Xiaoyong Yang,Fengping Jie,Bingjie Wang,Zhishan Bai
Environmental pollution by industrial effluents polluted with hazardous heavy metals has great concern. A novel microemulsion system (sodium dodecanoate/pentan-1-ol/heptane/NaCl) was prepared for the treatment of cobalt (Co) and manganese (Mn) wastewater. The effects of the batch extraction conditions were systematically studied and the extraction efficiency of Co(II) and Mn(II) were 98.2% and 97.5% respectively at the optimal conditions. Utilizing the centrifugal reinforcement of the annular centrifugal extractor (ACE), the continuous extraction of cobalt and manganese wastewater by microemulsion could be achieved. Under the optimized operation conditions: the motor speed of 1988 rpm, a flow ratio of 1/5, and a total flow rate of 48 L/h, the maximum extraction efficiency reached up to 99.9% for Co(II) and 99.1% for Mn(II), respectively. The stripping of Co(II) and Mn(II) from the microemulsion phase was also conducted using hydrogen chloride solution, indicating a high stripping efficiency. The investigation of synergistic extraction with microemulsion and ACE proposed an efficient treatment for Co and Mn wastewater.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2023
·Vol. 15
·期 6
·1330
·
IF 5
Kun Hou,Yafeng Yang,Hu Zhou,Xiangmeng Chen,Shengbo Ge
Water pollution has spurred the development of membrane separation technology as a potential means of solving the issue. In contrast to the irregular and asymmetric holes that are easily made during the fabrication of organic polymer membranes, forming regular transport channels is essential. This necessitates the use of large-size, two-dimensional materials that can enhance membrane separation performance. However, some limitations regarding yield are associated with preparing large-sized MXene polymer-based nanosheets, which restrict their large-scale application. Here, we propose a combination of wet etching and cyclic ultrasonic-centrifugal separation to meet the needs of the large-scale production of MXene polymers nanosheets. It was found that the yield of large-sized Ti3C2TxMXene polymers nanosheets reached 71.37%, which was 2.14 times and 1.77 times higher than that prepared with continuous ultrasonication for 10 min and 60 min, respectively. The size of the Ti3C2TxMXene polymers nanosheets was maintained at the micron level with the help of the cyclic ultrasonic-centrifugal separation technology. In addition, certain advantages of water purification were evident due to the possibility of attaining the pure water flux of 36.5 kg m−2h−1bar−1for the Ti3C2TxMXene membrane prepared with cyclic ultrasonic-centrifugal separation. This simple method provided a convenient way for the scale-up production of Ti3C2TxMXene polymers nanosheets.Keywords:Ti3C2TxMXene;yield;polymers nanosheets;cyclic ultrasonic-centrifugal separation
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2023
·
IF 7.4
Ruimin Song,Weigen Chen,Ziyi Wang,Zhixian Zhang,Yingzhou Huang,Jianxin Wang
Oil-paper insulated equipment is integral in power conversion and supports low-loss electricity transport. As a characteristic byproduct of the oil-paper insulation system, the realization of efficient detection of furfural in oil is crucial to the safe operation of the power grid. We proposed a novel approach using dual-enhanced Raman spectroscopy for sensing trace liquid components. This method employs a centrifugal extractor to separate and enrich the targeted components, achieving selective enhancement. The optimal phase ratio was determined to be 30:1. A liquid-core fiber was used to optimize the laser transmission efficiency and Raman signal collection efficiency, resulting in a nonselective signal enhancement of 44.86. It also investigated the impact of intermolecular interactions on the shift of Raman spectra, identifying the reasons for the differences in Raman signals between pure furfural, furfural in oil, and furfural in water. A batch of samples with furfural dissolved in insulation oil was measured using this system and achieved a limit of detection of 0.091 mg/L. The stability of the dual-enhanced Raman platform was experimentally verified with a spectral intensity fluctuation of 0.68%. This method is fast, stable, adaptable, and suitable for the detection of a wide range of liquid ingredients.
研究领域:
电力设备检测
·
光谱学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）