Research
·
2021
·
IF 0
Lijun Cai,Guopu Chen,Yuetong Wang,Cheng Zhao,Luoran Shang,Yuanjin Zhao
Microparticles with strong adherence are expected as efficient drug delivery vehicles. Herein, we presented an ingenious hydrogel microparticle recapitulating the adhesion mechanism of Boston ivy tendrils adhesive discs (AD) for durable drug delivery. The particles were achieved by replicating a silica colloidal crystal aggregates assembled in a droplet template after rapid solvent extraction. Due to their unique shape, the nanostructure, and the sticky hydrogel component, such novel microparticles exhibited prominent adhesive property to the wet tissue environment. It was demonstrated that the bioinspired microcarriers loading with dexamethasone had a good therapeutic effect for ulcerative colitis due to the strong adhesion ability for prolonging the maintenance of drug availability. These virtues make the biomimetic microparticles potentially ideal for many practical clinical applications, such as drug delivery, bioimaging, and biodiagnostics.
研究领域:
生物材料学
·
药剂学
·
生物医学工程
✓ 已验证
DOI
NATURE
·
2023
·Vol. 621
·期 7979
·511-515
·
IF 64.8
Yang Guangxu,Gong Zhenggang,Luo Xiaolin,Chen Lihui,Shuai Li
Plywood is widely used in construction, such as for flooring and interior walls, as well as in the manufacture of household items such as furniture and cabinets. Such items are made of wood veneers that are bonded together with adhesives such as urea–formaldehyde and phenol–formaldehyde resins 1 , 2 . Researchers in academia and industry have long aimed to synthesize lignin–phenol–formaldehyde resin adhesives using biomass-derived lignin, a phenolic polymer that can be used to substitute the petroleum-derived phenol 3 , 4 , 5 , 6 . However, lignin–phenol–formaldehyde resin adhesives are less attractive to plywood manufacturers than urea–formaldehyde and phenol–formaldehyde resins owing to their appearance and cost. Here we report a simple and practical strategy for preparing lignin-based wood adhesives from lignocellulosic biomass. Our strategy involves separation of uncondensed or slightly condensed lignins from biomass followed by direct application of a suspension of the lignin and water as an adhesive on wood veneers. Plywood products with superior performances could be prepared with such lignin adhesives at a wide range of hot-pressing temperatures, enabling the use of these adhesives as promising alternatives to traditional wood adhesives in different market segments. Mechanistic studies indicate that the adhesion mechanism of such lignin adhesives may involve softening of lignin by water, filling of vessels with softened lignin and crosslinking of lignins in adhesives with those in the cell wall.
研究领域:
材料科学
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林业工程
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Xiangming Hu,Jingran Mao,Qian Zhang,Xuechao Dong,Haigang Du,Mingyue Wu,Weimin Cheng,Zhenyu Yang
Understanding the adhesion mechanism between polydopamine (PDA) and coal surface is crucial for implementing the mussel strategy in self-adhesive gel for fire suppression. In this study, a combination of experiments and molecular simulations was utilized to explore the interfacial adhesion mechanism between PDA and coal. Initially, the adhesion potential of varying concentrations of PDA solutions was evaluated using a UV–Vis spectrophotometer, and in conjunction with contact angle/surface tension measurements, it was observed that adhesion strength did not show a direct correlation with PDA concentration. Subsequently, the adhesion sites of PDA on the coal surface were identified through spectroscopic analysis and confirmed using Dmol3 simulations. The study revealed that the amino and phenolic hydroxyl groups in the PDA structure could establish hydrogen bonds with oxygen-containing functional groups on the coal surface (e.g., COOH, OH, R-O-R'), while the aromatic rings in the molecules engaged in π-π stacking interactions. These non-covalent forces collectively facilitated the adhesion process. Molecular dynamics (MD) simulations were then employed to validate the relationship between PDA solution concentration and adhesion strength, which aligned with the experimental findings. Furthermore, the MD simulations elucidated how the concentration of PDA solution influenced its interfacial adhesion strength with coal by considering water molecule diffusion. Overall, this research offers a theoretical foundation for designing self-adhesive gel for fire suppression.
研究领域:
材料科学
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化学工程
·
分子生物学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Yuan Xu,Zhicheng Deng,Yun Chen,Fang Fang Wu,Chao Huang,Yong Hu
A novel mussel-inspired adhesive hydrogel with enhanced adhesion based on methacrylated catechol-chitosan (MCCS) and dopamine methacrylate (DMA) was prepared via photopolymerization. The structure and morphology of the MCCS/DMA adhesive hydrogel were investigated by using FTIR , NMR, XRD, TG, and SEM. The rheological and texture properties, swelling and degradation characteristics, as well as the adhesion mechanism of the hydrogels were also examined. These results revealed that the MCCS/DMA hydrogels have a dense double cross-linking network structure with porous internal microstructures, and exhibited controllable swelling and degradation properties, good thermostability , and stable rheological characteristics. Furthermore, the adhesive mechanism of MCCS/DMA hydrogel has been confirmed by the FTIR and 2D correlation FTIR spectroscopy . Additionally, the results of in vitro cytotoxicity assessment indicated that the resulting hydrogels have good cytocompatibility. Overall, the MCCS/DMA adhesive hydrogel may have potential applications in medical bioadhesives.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2016
·Vol. 4
·期 16
·3467-3476
·
IF 5.066
Juanjuan Wang,Jixun Xie,Chuanyong Zong,Xue Han,Haipeng Ji,Jingxin Zhao,Conghua Lu
Here, we report simple novel surface treatment-assisted switchable transfer printing (sTP) to pattern polydimethylsiloxane (PDMS) films of diverse thicknesses with prescribed microstructures. In the sTP, the PDMS decal inks are transferred from the “soft” side to the “hard” side, irrespective of the “soft” side coming from the PDMS stamp or the target PDMS substrate. Their “soft/hard” contrast with the corresponding cohesion difference can be finely induced and switched by a simple surface oxidation treatment, yielding the customized transfer patterns. In particular, multiple sTP with smart combinations of the additive/subtractive transfer mode can be easily realized for the controlled fabrication of unprecedented hierarchical patterns. We demonstrate the application of this methodology for forming microfluidic systems and as masks for surface patterning, and it is a powerful candidate for photolithography. Systematic studies further provide insights into the involved cohesion–fracture mechanism, which is highly expected to apply to other functional systems for advanced micro–nanofabrication.
研究领域:
材料科学
·
微纳米制造
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2017
·
IF 3.833
Meng Qi,Xiangjun Gong,Bo Wu,Guangzhao Zhang
Landing of bacteria for adhesion on a surface is a common phenomenon in our life. However, how surface properties are involved in this process remains largely unclear. Using digital holographic microscopy, we investigated the three-dimensional motions of flagellate Escherichia coli swimming near polymeric surfaces with different properties in aqueous solution before adhesion. We monitored the bacteria landing dynamics, which shows that the density distribution, the probability, and the orientation for collisions of the bacteria are determined by their motility but are slightly affected by the surface properties. However, surface hydrophobicity reduces the near-wall velocity of the bacteria through collisions and slightly increases the collision duration. This promotes the landing and adhesion of bacteria. By contrast, most bacteria collide with the surface using their flagella, which resist adhesion.
研究领域:
生物医学工程
·
微生物学
·
软物质物理
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生物界面科学
·
生物膜形成
✓ 已验证
DOI
高影响因子
SURFACE AND INTERFACE ANALYSIS
·
2021
·Vol. 53
·期 12
·1048-1058
·
IF 1.607
Xinjie Chen,Shiai Xu
In this study, an environmentally friendly molybdate (Mo) conversion coating was deposited on the surface of aluminum (Al) foil for use as the packaging film of lithium-ion battery, and the surface morphology and chemical composition were characterized by field emission scanning electron microscopy (FE-SEM), atomic force microscopy (AFM), energy dispersive spectroscopy (EDS), and X-ray photoelectron spectroscopy (XPS). The XPS results show that the conversion coating is composed of MoO 3 , MoO x , Al 2 O 3 , and (MoO 3 ) x (P 2 O 5 ) y . Then, the effects of treatment time on the corrosion resistance of Al foil and the adhesive strength between Mo-treated Al foil and maleic anhydride (MAH)-grafted polypropylene (MPP) were investigated. It is revealed that both the peeling strength and the corrosion resistance of Mo-treated Al foil increase with the treatment time.
研究领域:
材料科学
·
表面工程
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Physical Chemistry C
·
2015
·
IF 4.772
Dong Yang,Yuanyuan Sun,Zhenwei Tong,Yao Tian,Yuanbing Li,Zhongyi Jiang
Inspired by the bioadhesion mechanism found in mussel, a catechol derivative, 3-(3,4-dihydroxyphenyl)propionic acid (diHPP), is employed as both linker and reducer of Ag+ to synthesize the Ag/TiO2 nanotube (Ag/TNT) heterojunction under ambient conditions in this study. In the prepared Ag/TNT composite, Ag nanocrystals about 3.8 nm in diameter distribute over the TNT surface uniformly and form the heterojunction structure with TNT. The diHPP first links to the TNT surface through the bidentate chelation of catechol group with Ti4+ and then acts as both an anchor and a reducer to in situ nucleate and grow Ag nanocrystals on the TNT surface. By adjusting the AgNO3 concentration, the loading amount of Ag nanocrystals on the TNT surface can be controlled easily, and the visible-light absorption ability of Ag/TNT heterojunctions enhances with increasing the Ag loading amount. Moreover, their photocatalytic activity was evaluated by the degradation capability of Rhodamine B (RhB) under visible light. The Ag/TNT heterojunctions exhibit the high visible-light photocatalytic activity, which can almost degrade 100% RhB within 2 h. This excellent performance can be attributed to the local electric field caused by the surface plasmon resonance (SPR) of Ag nanocrystals and the high adsorption capability of TNTs with large specific surface area.
研究领域:
材料科学
·
环境科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Gansheng Liu,Zhiyou Pu,Christine Matindi,Zhenyu Cui,Hong Wang,Jianhua Yang,Jianxin Li
Three nanofiltration (NF) membranes (positive charge, negative charge and near charge neutrality) were fabricated to investigate the anti-adhesion mechanism. Among them, the NF membrane with positive charge was synthesized through an electrophilic substitution reaction between the amino group of polyethyleneimine (PEI) and the chloromethyl groups of chloromethyl polysulfone (CMPSf) on a supporting polysulfone (PSf)/CMPSf blend membrane. The NF membrane with negative charge was fabricated through polycondensation using 1, 3, 5-benzenetricarbonyl trichloride (TMC) as a reactive monomer on the positive charge NF membrane. Subsequently, the near charge neutral zwitterion NF membrane (ZNF) was prepared by grafting 3-((2-aminoethyl) dimethylammonio) propane-1-sulfonate (sulfobetaine) (ADSS) onto the negative charge NF membrane. The anti-adhesion behaviors of the NF membranes during the dye selective separation were analyzed by Atomic force microscopy (AFM) and quartz crystal microbalance with dissipation (QCM-D). The results demonstrated that the near charge neutral ZNF membrane displayed a higher dyes rejection (>94.4 %) and higher flux recovery rates (>88.1 %) than charged NF membranes. Meanwhile, the near charge neutral ZNF membrane demonstrated the lowest amounts of dye deposition compared with charged NF membranes, such as reactive blue 4 (R4) for 509.9 ng/cm 2 , basic blue 24 (BB 24) for 269.0 ng/cm 2 , rhodamine B (RB) for 197.4 ng/cm 2 ). Additionally, the near charge neutral ZNF membrane with the thicker hydration layer (121.7 nm) displayed weaker interaction forces (−4.8 nN to −7.4 nN) with the dyes than the charged membranes (−10.4 nN to −28.6 nN). Finally, an anti-adhesion mechanism involved charged shielding effect and hydration layer formation was proposed. These observations provide comprehensive insights into the anti-adhesion mechanism of ZNF membrane.
研究领域:
材料科学
·
膜技术
·
表面化学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2024
·
IF 5.3
Qixiang Zhan,Shuhua Deng,Jiayi He,Jinhua Xu,Anfu Chen,Jiajun Luo,Wenjie Zhang,Caihong Lei
The elasticity mismatch between Ti and tissue limits the performance of Ti medical devices. How to create a coating with mimicking natural soft tissue stiffness and possessing strong mechanical bond is a challenge in implant manufacturing. Here, we developed a combined coating, that is, an anodized Ti surface (ATS) with nanostructures coated with a layer of PAAm hydrogel with tunable elasticity. Due to the nano-mechanical interlocking and hydrogen bonding synergy, the PAAm hydrogel layer was tightly anchored in nanostructures on the ATS. By regulating the oxidation voltage, nanostructures including nanopores, nanotubes, and punch-through nanotubes were fabricated on the ATS, and these three kinds of anodized nanostructures increase the porosity of the ATS sequentially. The lap shear test has shown that the shear strength increases linearly with increasing the porosity, and the shear strength of the punch-through nanotube structures with the PAAm hydrogel coating reaches 59.28 kPa. The adhesion mechanism between the anodized Ti nanostructures and the PAAm hydrogel coating is mainly due to the nano-mechanical interlocking and hydrogen bonding synergy, which was proven by morphology analysis, XRD, and ATR-FTIR characterization of the samples subjected to lap shear load. The hydrogel-nanostructures coating has demonstrated the potential to be applied in Ti medical devices.
研究领域:
生物材料
·
材料科学
·
组织工程
·
机械工程
✓ 已验证
DOI
高影响因子
POLYMER
·
2022
·
IF 4.432
Bo Zhang,Songyue Liu,Lijie Yin,Ming Tian,Nanying Ning,Liqun Zhang,Wencai Wang
The reaction mechanism and the interfacial modulus gradient of the interfacial transition layer between the environmentally friendly dipping system (PAL) and the rubber have not been fully studied. In order to better understand the chemical structures and nano-mechanical properties of the interface between the dip layer and the rubber, we used advanced atomic force microscope (AFM) and nanoscale Fourier transform infrared spectroscopy (nano-FTIR) to perform detailed analysis in this article. The characterization of interfacial nano-mechanical properties and chemical structures is very significant for the illustration of interfacial adhesion mechanism. AFM can effectively characterize the detailed interfacial modulus gradient and the thickness of interface, while nano-FTIR can comprehensively measure the interfacial chemical structures and the distribution of chemical bonds. The results suggest that the thickness of the interface between the PAL dip layer and the rubber matrix is 175 nm, and the crosslinking density of the interfacial layer is high, which explains that the failure location of fiber/rubber composites after pull-out tests occurs on the side of the rubber matrix. Similarly, the microstructure of resorcinol-formaldehyde-latex (RFL) system was also characterized, and the preparation of RFL usually requires carcinogenic and toxic substances such as formaldehyde and resorcinol .
研究领域:
材料科学
·
复合材料
·
纳米技术
·
高分子科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）