SCIENCE OF THE TOTAL ENVIRONMENT
·
2022
·
IF 10.753
Xuqian Zhang,Ying He,Zitong Yuan,Guangmao Shen,Zan Zhang,Jinzhi Niu,Lin He,Jinjun Wang,Kun Qian
Thiacloprid is a new chlorinated nicotinoid insecticide against stinging-oral pests, such as aphids. It is less toxic to bees but more toxic to earthworms. In this study, a pH- and amylase-responsive MOF (ZIF-8) was constructed for site-specific delivery of thiacloprid to control pea aphids and more safety for earthworms. Thiacloprid from α-cyclodextrin@Thiacloprid@ZIF-8 (α-CD@T@ZIF-8) could be released quickly in pea aphids, which was ascribed to disintegration of ZIF-8 at low pH values in pea aphid intestines and degradation of α-CD under the action of α-amylase. The release results showed a significant pH dependence of α-CD@T@ZIF-8, with an approximately 65 % release amount at pH = 7 and a 95 % release amount at pH = 5 for 7 d. The results of the pot experiment and biosafety showed that for α-CD@T@ZIF-8, 88 % pea aphids could be killed compared with 32 % aphids for commercially available formulation on the 7th day after application. Meanwhile the LC 50 of thiacloprid OD was 0.034 μg/cm 2 and the LC 50 of α-CD@T@ZIF-8 was 0.564 μg/cm 2 on earthworms, and it was more safety for pea and lower acute toxicity and enrichment for the earthworms. α-CD@T@ZIF-8 could be used for intelligently controlled release of other insecticides against aphids.
研究领域:
农业科学
·
环境科学
·
昆虫学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 24
·2022
·
IF 4.4
Qiongmei Mai,Yu Lu,Qianyu Cai,Jianglong Hu,Yunyou Lv,Yonglan Yang,Liqiang Wang,Yuezhao Zhou,Jie Liu
Sclerotinia sclerotiorumis one of the fungi that cause plant diseases. It damages plants by secreting large amounts of oxalic acid and cell wall-degrading enzymes. To meet this challenge, we designed a new pH/enzyme dual-responsive nanopesticide Pro@ZnO@Pectin (PZP). This nanopesticide uses zinc oxide (ZnO) as a carrier of prochloraz (Pro) and is encapsulated with pectin. When encountering oxalic acid released bySclerotinia sclerotiorum, the acidic environment promotes the decomposition of ZnO; at the same time, the pectinase produced bySclerotinia sclerotiorumcan also decompose the outer pectin layer of PZP, thereby promoting the effective release of the active ingredient. Experimental data showed that PZP was able to achieve an efficient release rate of 57.25% and 68.46% when pectinase was added or under acidic conditions, respectively. In addition, in vitro tests showed that the antifungal effect of PZP was comparable to that of the commercial Pro (Pro SC) on the market, and its efficacy was 1.40 times and 1.32 times that of the Pro original drug (Pro TC), respectively. Crucially, the application of PZP significantly alleviated the detrimental impacts of Pro on wheat development. Soil wetting experiments have proved that PZP primarily remained in the soil, thereby decreasing its likelihood of contaminating water sources and reducing potential risks to non-target organisms. Moreover, PZP improved the foliar wettability of Pro, lowering the contact angle to 75.06°. Residue analyses indicated that PZP did not elevate prochloraz residue levels in tomato fruits compared to conventional applications, indicating that the nanopesticide formulation does not lead to excessive pesticide buildup. In summary, the nanopesticide PZP shows great promise for effectively managingSclerotinia sclerotiorumwhile minimizing environmental impact.
研究领域:
植物病理学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Jincan Liu,Dejin Xu,Guangchun Xu,Xiaona Li,Jiangtao Dong,Xingkun Luan,Xuezhong Du
Nanopestcides based on metal–organic frameworks (MOFs) have attracted great attention. Highly stable mesoporous metal–organic framework PCN-777 with large pores can accommodate the biologically active insecticide avermectin (AVM) of relatively large molecular dimensions. In this work, PCN-777 nanoparticles were synthesized for the creation of double-gated nanopesticides with sodium lignosulfonate (SL) and chitosan. The double gatekeepers could realize excellent sealing performance to prevent premature leakage of AVM. The double-gated PCN-777 based nanopesticides could achieve the controlled release of AVM in response to pH, laccase, phosphate, and phytic acid (PA), which are related to the physiological environments of pests and crops. The PA-triggered controlled release of loaded cargos in MOF-based delivery systems was reported for the first time. This is the first example of PCN-777 drug/pesticide delivery system and also the first case of controlled-release MOF-based AVM nanopesticides, and the mechanisms of the stimuli-responsive controlled pesticide release were clearly elucidated. The nanopesticides prevented the ultraviolet photolysis of AVM owing to the PCN-777 organic ligands and SL coating. The nanopesticides had high insecticidal efficacy and field control efficacy against the pests Spodoptera litura Fabricius on cabbage, in comparison with traditional pesticide formulations, and the nanopesticides had no influence on plant growth and showed high biosafety toward non-target organisms and human cells. The smart controlled-release nanopesticides show high potential and application prospect in ecological agriculture.
研究领域:
农业科学
·
生物技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 21
·3844
·
IF 5.719
Zhenlan Xu,Qing Tang,Aimei Hong,Lingxiangyu Li
Along with the development of nanotechnology, nanomaterials have been gradually applied to agriculture in recent years, such as Cu(OH)2-nanorods-based nanopesticide, an antibacterial agrochemical with a high efficacy. Nevertheless, knowledge about physical stability of Cu(OH)2nanopesticide in soil solutions is currently scarce, restricting comprehensive understanding of the fate and risk of Cu(OH)2nanopesticide in the soil environment. Herein we investigated aggregation, sedimentation and dissolution of Cu(OH)2nanopesticide in soil solutions extracted from three different soil samples, wherein commercial Cu(OH)2nanopesticide formulation (NPF), as well as its active ingredient (AI) and laboratory-prepared Cu(OH)2nanorods (NR) with similar morphology as AI, were used as model Cu(OH)2nanopesticides. We found that NPF compared to AI showed less extents of aggregation in ultrapure water due to the presence of dispersing agent in NPF. Yet, moderated aggregation and sedimentation were observed for Cu(OH)2nanopesticide irrespective of NPF, AI or NR when soil solutions were used instead of ultrapure water. The sedimentation rate constants of AI and NPF were 0.023 min−1and 0.010 min−1in the ultrapure water, whereas the rate constants of 0.003–0.021 min−1and 0.002–0.007 min−1were observed for AI and NPF in soil solutions, respectively. Besides aggregation and sedimentation, dissolution of Cu(OH)2nanopesticide in soil solutions was highly dependent on soil type, wherein pH and organic matter played important roles in dissolution. Although the final concentrations of dissolved copper (1.08–1.37 mg/L) were comparable among different soil solutions incubating 48 mg/L of AI, NPF or NR for 96 h, a gradual increase followed by an equilibrium was only observed in the soil solution from acidic soil (pH 5.16) with the low content of organic matter (1.20 g/kg). This work would shed light on the fate of Cu(OH)2nanopesticide in the soil environment, which is necessary for risk assessment of the nanomaterials-based agrochemical.Keywords:soil solutions;aggregation;sedimentation;Cu(OH)2nanopesticide;dissolution
研究领域:
环境科学
·
农业科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
·
2020
·
IF 1.101
Yunhao Gao,Donglin Li,Dongyang Li,Pengfei Xu,Kaikai Mao,Yunhua Zhang,Xueying Qin,Tao Tang,Hu Wan,Jianhong Li,Mingcheng Guo,Shun He
Nanopesticides with antiwashing capacity on leaves are the most promising new approaches for sustainable pest management and have been fully evaluated in the laboratory. However, few studies have tested these nanopesticides on pests, and their efficacy under field conditions has not been investigated. In this study, an adhesive hollow mesoporous silica hybrid with well-defined spherical shape and good monodispersity was used as a nanocarrier of cyantraniliprole (CNAP) to fabricate an adhesive nanopesticide (CNAP-HMS-PDAAM). The control efficacy of CNAP-HMS-PDAAM was tested under field conditions. The results indicated that the efficacy of four doses of CNAP-HMS-PDAAM (30.0–69.0 g a.i./ha) against Cnaphalocrocis medinalis (Guénee) 3, 7, and 14 days after spraying did not significantly differ from that of Benevia (34.5 g a.i./ha). Twenty-eight days after spraying, the efficacy of all four doses of CNAP-HMS-PDAAM was significantly better than that of Benevia. Additionally, the efficacy of CNAP-HMS-PDAAM at doses of 34.5, 39.0 and 69.0 g a.i./ha against Chilo suppressalis (Walker) were significantly higher than that of Benevia (34.5 g a.i./ha). Thus, CNAP-HMS-PDAAM showed long-term control efficacies against C. medinalis (Guénee) and C. suppressalis (Walker), mainly due to its strong adhesive property on rice leaves and its sustained release properties. In addition, the nanocarriers showed good biocompatibility and had no obvious influence on the growth of rice.
研究领域:
农业科学
·
植物保护
·
材料科学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Qinhong Jiang,Min Dong,Lin Che,Che Li,Xian Zhang,Meizhen Yin,Jie Shen,Shuo Yan
The continuous screening of high-efficiency RNAi targets is labor-consuming and time-costing, which constrains the fast commercialization of RNA pesticides. Thus, incorporating synergistic active ingredients via co-delivery nano-platform offers a promising solution without the need for high-efficiency RNAi targets. The current study aimed to propose a standard strategy for developing multicomponent nanopesticides. The function analysis revealed that the decapentaplegic-like ( Dpp ) participated in fatty acid biosynthesis and cuticle formation, and its RNAi resulted in molting failure and death in destructive green peach aphids. However, the morality caused by Dpp RNAi could not meet the actual demand, and thus a potential synergistic pesticide spirotetramat (SPI) was introduced to assemble with star ploycation (SPc) and ds Dpp to construct a co-delivery nano-platform. The SPc could assemble with SPI into SPI/SPc complex, and the ds Dpp could be further adhered on the surface of complex through electrostatic interaction, which formed stable spherical particles with nanoscale size (322.95 nm) and positive charge (28.22 mV). Notably, the SPI/SPc/ds Dpp complex displayed better adhesion performance on plant leaves, and thus the plant uptake of SPI/SPc/ds Dpp complex was remarkably improved in vivo and in vitro. Meanwhile, the SPI/SPc/ds Dpp complex exhibited amplified contact area on aphid cuticle, and its translocation was improved across the aphid cuticle/cell membrane. Importantly, the stomach and contact toxicity of SPI/SPc/ds Dpp complex was the strongest with the highest aphid mortalities of 94.5 %–96.6 %. The co-delivery nano-platform improved both initial action time and overall bioactivity, addressing the short life disadvantage of ds Dpp and slow-acting property of SPI. Our work proposed a standard strategy for designing multicomponent nanopesticides, which could facilitate the fast commercialization of RNA pesticides.
研究领域:
分子生物学
·
农业昆虫学
·
纳米技术
·
农药科学
✓ 已验证
DOI
高影响因子
PEST MANAGEMENT SCIENCE
·
2023
·Vol. 80
·期 4
·2120-2130
·
IF 4.1
Ximing Zhong,Guofeng Su,Li Hao,Huayao Chen,Chao Li,Hua Xu,Hongjun Zhou,Xinhua Zhou
BACKGROUND Root-knot nematodes (RKNs) are the highly damaging pests for various crops, and the prevalence of RKNs has posed serious threats to worldwide agricultural harvest, severely affecting global food security and ecosystem health. Traditional pesticide systems on controlling RKNs generally cause environmental hazards and phytotoxicity due to the excessive use of pesticides resulted from low utilization efficiency. And effective approaches with biosafe and efficient features are highly demanded to break away from the dilemma caused by RKNs. RESULTS In this research, a nanopesticide system with root-targeted delivery function was developed to achieve effective prevention and control of RKNs. The nanocarriers (MSN-KH560-Gly) and the obtained nanopesticides (EB@MSN-KH560-Gly) were proved to be biosafe. Also, this nanopesticide system demonstrated sustained release behavior. The grafting of glycine (Gly) significantly improved the pesticide contents translocating to cucumber roots (about 304.7%). Besides, such root-targeted delivery function resulted in no root nodule in cucumber plants after the foliar application of these nanopesticides (prevention rate of 100%). In addition, the root nodule numbers of the infected cucumber plants decreased by 71.67%. CONCLUSION Foliar application of these Gly-functionalized nanopesticides achieved effective prevention and control of RKNs due to the root-targeted delivery property inherent in this nanopesticide system, and such root-targeted delivery strategy opens a novel and efficient method to protect crops from RKN invasion and thus facilitates the development of sustainable agriculture. © 2023 Society of Chemical Industry.
研究领域:
农业科学
·
植物保护学
·
生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Wen Sun,Qi Yuan,Mingyue Tan
Nanotechnology integration into agricultural science and technology has led to the development of nano-pesticides, which are pivotal in enhancing the efficacy of pest control and reducing the environmental footprint of traditional pesticides. However, there is a significant knowledge gap regarding the absorption, transportation, and distribution of nanoparticle carriers within crops, which is essential for the safe and effective application of these nano-pesticides. Taking advantage of high sensitivity and minimal interference from biological backgrounds, herein, surface-enhanced Raman scattering (SERS) labeling technology was applied to track the in vivo distribution of nano-pesticide carriers in plant. AuNS@Cy7@TiO 2 model NPs with distinct near-infrared SERS signals were synthesized applied to ginseng leaves to monitor their behavior. SERS imaging results demonstrate that these NPs can migrate from treated leaflets to adjacent leaflets and petioles, penetrating the mesophyll tissue and distributing uniformly. Importantly, the absence of SERS signals in the aerial stem indicates that the NPs do not translocate to the roots, thus posing minimal risk to the medicinal parts of ginseng. The presence of the surfactant Silwet L-77 increases the migration distance of nanoparticles within the leaves. This study highlights the potential of SERS labeling for tracking NP movement in plants, providing insights into the absorption and transport mechanisms of nanocarriers, and guiding the development of safer and more effective nano-pesticides.
研究领域:
植物学
·
农业科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Environmental Science-Nano
·
2023
·Vol. 11
·期 1
·363-372
·
IF 7.3
Long Chen,Jiamin Hu,Haiwei Pang,Shuyan Yin,Huixiang Liu,Yehan Tian,Shangkun Gao,Chenggang Zhou,Puxia Wu,Shuo Miao,Yingchao Ji,Chaoqiong Liang,Yanxue Liu
Pine wilt disease (PWD) is an infestation caused by pine wood nematodes (PWN, Bursaphelenchus xylophilus), and has caused significant disruption to forest ecosystems worldwide. Trunk injection is effective in controlling PWD, but the long-term use of abamectin (AVM) and other drugs in large quantities has caused resistance problems, and the annual trunk injections have caused some damage to the trunks themselves. In order to reduce drug resistance and damage to the tree trunks, in this study, dendritic mesoporous silica nanoparticles (DMSNs) were prepared by using a “one-pot” method, which is the easiest to industrialise, and AVM@DMSNs nano-pesticides with a uniform particle size, high loading efficiency (80.2%) and sustained release were prepared by physical adsorption. And cellular uptake and toxicity experiments were carried out on sf9 cells, and the results showed that the nano DMSNs could be enriched on sf9 cells and had good inhibition of cellular activity. The lethality of the nano-pesticides AVM@DMSNs and AVM on PWN was investigated using the insect dip method. The results showed that the corrected mortality rate of AVM@DMSNs was significantly higher than that of free AVM within 72 h. In addition, AVM@DMSNs compounded with a plant essential oil bark penetrant could be applied locally outside the bark and penetrate the drug into the tree to achieve the purpose of injury-free drug delivery, which could effectively reduce the damage of perforation injection on the tree and provide a new way for the control of forest pests.
研究领域:
植物保护
·
森林生态学
·
纳米生物学
✓ 已验证
DOI
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Fei Teng,Zhaogui Wang,Mingyu Xue,Hui Li,Quanmin Wen,Peng Xu,Dejun Hao
Pine wilt disease is caused by Bursaphelenchus xylophilus invasion and has a great impact on global pine resources. Injection of emamectin benzoate (EB) into pine trunks is an effective way to control B. xylophilus. However, EB has limited aqueous solubility, easily photodissociates, and its long-term use causes resistance problems. In this study, the metal–organic framework material ZIF-8 was prepared, and EB was loaded onto ZIF-8 through physical adsorption, resulting in a pH-responsive EB@ZIF-8 nanopesticide with a high drug loading rate (36.04%). Simulated release experiments of EB@ZIF-8 under different pH conditions showed a cumulative release of 64.43% within 10 h at pH 5.0, which increased as the pH decreased, compared to conditions at pH 7.0 and 9.0. EB@ZIF-8 showed positive insecticidal activity in a laboratory biological test (LC50 = 52.503 mg/L). In addition, 7 days after trunk injection in Pinus massoniana, EB residuals were detected in all parts of the branches, with the lowest residue level being 73.39 mg/kg. The proportion of the EB residue in the lower, middle, and upper branches of P. massoniana gradually increased, reaching 43.92% at 28 days after trunk injection, indicating that EB was distributed evenly in the tree. Therefore, EB@ZIF-8 had good morphology, structure, and pH-responsive release performance. EB@ZIF-8 also exhibited a high nematocidal ability due to its smaller particle size and rapid transport in P. massoniana. This study provides a new approach for the development of highly effective EB preparations, improvement of pesticide utilization, and B. xylophilus control.
研究领域:
植物保护
·
材料科学
·
农业科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Agricultural Science & Technology
·
2025
·
IF 2.9
Bin Sheng,Ying Zhang,Kexin Yang,Xiaobin Wen,Zhihao Lin,Zhijian Wu,Yaowei Zhang,Jie Zhou,Xueling Ye,Miao Wang,Ge Chen,Guangyang Liu,Xiaomin Xu,Xin Yang,Bining Jiao,Donghui Xu
Neonicotinoid insecticides face a number of challenges in improving the efficacy and mitigating resistance in Bemisia tabaci. The zeolitic imidazolate framework (ZIF) in metal–organic frameworks (MOFs) has attracted much attention in the field of nanopesticide preparation and controlled release due to its simple preparation. However, monometallic ZIFs have a simple structure and low loading capacity. To solve this problem, we doped Fe into ZIF-L and successfully synthesized a cross-stacked bimetallic ZIF nanocarrier, which can effectively load and release dinotefuran (DNF). Subsequent preparation of Zn-Fe-ZIF@DNF@MPN after encapsulation using metal–phenolic networks (MPNs) increased the DNF loading to 23.74% and achieved >99% release within 24 h. Zn-Fe-ZIF@DNF@MPN has greater resistance to UV light, retention on vegetable leaves, and resistance to rainwater washout. Dynamic residue analysis confirmed its effectiveness and persistence. In addition, it achieved 86.95% mortality against Bemisia tabaci without inhibiting cabbage seed germination. This work is of strategic importance for the development of a functional and environmentally friendly smart nanopesticide.
研究领域:
农药学
·
材料科学
·
昆虫毒理学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
PEST MANAGEMENT SCIENCE
·
2021
·Vol. 78
·期 2
·506-520
·
IF 4.845
Ming Zhao,Hongjun Zhou,Li Hao,Huayao Chen,Xinhua Zhou
BACKGROUND As the global population grows, large quantities of agrochemicals are used to secure food demand and there is an urgent need to develop efficient and environmentally friendly pesticides and fertilizers. Compared with traditional pesticides, nanopesticide formulations can achieve better foliar wettability, chemical stability, and water dispersibility without or with the minimal use of organic solvents, in line with the development of sustainable agriculture. RESULTS In this research, glycidyl methacrylate (GMA) was used as an intermediate and glycine methyl ester (GLY) was used as an organic nitrogen source to modify carboxymethyl cellulose (CMC) to synthesize a pesticide nanocarrier CMC-PGMA-GLY. A nanopesticide EB@CMC-PGMA-GLY (EB@CPG) was formed by the hydrophobic and electrostatic interactions of emamectin benzoate (EB), which had good water dispersion. The good affinity of the composite towards leaves led to the effective moistening of the leaf surface by the pesticide and through the pH control pesticide release. Biological experiments show that nanopesticides can maintain high insecticidal activity and have no toxicity to seed germination. The results of pot experiment showed that the nanocarriers could be used as an organic nitrogen fertilizer to increase the fresh weight of plants by 39.77%. CONCLUSIONS This environmentally friendly pesticide carrier can be used as a fertilizer to provide sufficient nutrients for crops, opening a new method for the development of sustainable agriculture. © 2021 Society of Chemical Industry.
研究领域:
农业科学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）