Nature Communications
·
2024
·Vol. 15
·期 1
·1-12
·
IF 14.7
Gao Peng,Hu Yezi,Shen Zewen,Zhao Guixia,Cai Ruiqing,Chu Feng,Ji Zhuoyu,Wang Xiangke,Huang Xiubing
Consecutive uranium extraction from seawater is a promising approach to secure the long-term supply of uranium and the sustainability of nuclear energy. Here, we report an ultra-highly efficient strategy via studtite nanodots growth with impressive uranyl uptake capacity of ~ 154.50 mg/g from natural seawater in 12 consecutive days (i.e., average for ~ 12.875 mg/g/day). Uranyl can be extracted as studtite under visible light via the reaction between the adsorbed uranyl and the photogenerated H 2 O 2 with imine-based Covalent-Organic Framework photocatalysts. In detail, over Tp-Bpy, Tp-Bpy-2 and Tp-Py with multiple uranyl chelating sites, uranyl is found extracted as studtite nanodots which can be eluted readily, while over Tp-Bd and Tb-Bpy, uranyl is transformed into studtite nanorods that is more inert for elution. Abundant chelating sites of uranyl via structural regulation of COF photocatalysts are proved to facilitate the formation and efficient elution of studtite nanodots.
研究领域:
核能科学
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材料科学
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环境科学
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DOI
高影响因子
Nature Nanotechnology
·
2025
·
IF 34.9
Huang Wei-Qiang,You Wei,Zhu Ya-Qi,Gao Fan,Wu Zhi-Zhi,Chen Guang,Xiao Jun,Shao Qi,Wang Long-Hai,Nie Xuan,Zhang Ze,Hong Chun-Yan,You Ye-Zi
Autophagosome cancer vaccines can promote cross-presentation of multiple tumour antigens and induce cross-reactive T cell responses. However, so far, there is no effective method for obtaining a highly immunogenic autophagosomal cancer vaccine because autophagosomes, once formed, quickly fuse with lysosomes and cannot easily escape from cells. Here we report a functional Ti 2 NX nanodot that caps the autophagosome membrane lipid phosphatidylinositol-4-phosphate, blocking the fusion of autophagosomes with lysosomes and producing stable nanodot-coated autophagosomes in tumours. The formed nanodot-coated autophagosomes can escape from cancer cells to lymph nodes, where they activate tumour-specific T cells. We show that our approach reduces tumour burden and provide long-term immune surveillance protection for cured mice. This work provides a method for the direct formation of personalized autophagosome-based cancer vaccines in vivo, offering a promising strategy for tumour treatment.
研究领域:
肿瘤学
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免疫学
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2020
·Vol. 11
·期 1
·1-8
·
IF 12.121
Li Siqi,Lei Dangyuan,Ren Wei,Guo Xuyun,Wu Shengfan,Zhu Ye,Rogach Andrey L.,Chhowalla Manish,Jen Alex K.-Y.
Owing to their large absorption cross-sections and high photoluminescence quantum yields, lead halide perovskite quantum dots (PQDs) are regarded as a promising candidate for various optoelectronics applications. However, easy degradation of PQDs in water and in a humid environment is a critical hindrance for applications. Here we develop a Pb-S bonding approach to synthesize water-resistant perovskite@silica nanodots keeping their emission in water for over six weeks. A two-photon whispering-gallery mode laser device made of these ultra-stable nanodots retain 80% of its initial emission quantum yield when immersed in water for 13 h, and a two-photon random laser based on the perovskite@silica nanodots powder could still operate after the nanodots were dispersed in water for up to 15 days. Our synthetic approach opens up an entirely new avenue for utilizing PQDs in aqueous environment, which will significantly broaden their applications not only in optoelectronics but also in bioimaging and biosensing.
研究领域:
光电子学
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材料科学
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光子学
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纳米技术
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生物成像
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生物传感
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产品关联
DOI
PubMed
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2023
·Vol. 25
·期 24
·16438-16445
·
IF 3.3
Zhiwei Yang,Lijuan Dong,Qian Chen,Zeyi Wang,Jiacheng Cao,Mengwei Dong,Jian Wang,Jian Zhang,Xiao Huang
Although titanium-based MXenes have been widely reported for gas sensing, the effect of crystal stoichiometric variations on the sensing properties has been rarely reported. Herein, stoichiometric polymorphs of titanium carbide MXenes (i.e., Ti3C2Tx and Ti2CTx) loaded with Pd nanodots (NDs) prepared by photochemical reduction were investigated for room-temperature H2 sensing. Interestingly, we found that Pd/Ti2CTx exhibited greatly enhanced sensitivity to H2, along with faster response and recovery rates compared to Pd/Ti3C2Tx. The H2 adsorption induced resistance change in Pd/Ti2CTx was higher than that of Pd/Ti3C2Tx due to the more effective charge transfer at the heterointerface of Pd/Ti2CTx, which was confirmed by shifts of binding energies and theoretical calculation results. We hope this work could be helpful to design more high-performance MXene-based gas sensors.
研究领域:
材料科学
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传感器技术
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表面化学
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产品关联
DOI
PubMed
高影响因子
ACS Catalysis
·
2023
·
IF 12.9
Qian Zhang,Mingzi Sun,Chen-Yue Yuan,Qi-Wen Sun,Bolong Huang,Hao Dong,Ya-Wen Zhang
Constructing abundant surface/interface structures has significant impacts on improving the performance of electrochemical CO2 reduction reaction (CO2RR) catalysts. For developing high-performance CO2RR catalysts, herein we report a 0D/2D heterojunction structure of SnO2 nanodots (∼2 nm) confined on graphitic carbon nitride (g-C3N4) nanosheets for promoting the conversion of CO2 to formate. Experimental and theoretical studies demonstrate that the abundant N-coordinating sites of g-C3N4 and highly distributed SnO2 nanodots synergistically lead to strong metal oxide–support interactions, and the substantial heterojunction interface in SnO2/g-C3N4 has induced efficient electron transfer from electron-rich g-C3N4 to SnO2 mainly through p–p orbital couplings. As a result, the SnO2/g-C3N4 heterojunction provides superior activity and stability for the conversion of CO2RR to formate, with a Faradic efficiency of 91.7% at −0.88 V vs RHE. Moreover, the proposed 0D/2D heterojunction strategy was extended to In2O3/g-C3N4, supplying a universal strategy to achieve efficient hybrid catalysts for CO2RR in the production of high-value chemicals.
研究领域:
材料科学
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电化学
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催化反应
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产品关联
DOI
高影响因子
ACS Nano
·
2024
·
IF 15.8
Yanzhi Dong,Gang Shu,Yibo Wei,Jinbin Pan,Dong Li,Shao-Kai Sun
Tantalum (Ta) emerges as a promising element for advanced computed tomography (CT) imaging probes owing to its high X-ray attenuation coefficient and excellent biocompatibility. Nevertheless, the synthesis of renally clear Ta-based imaging probes through simple methods remains a significant challenge. Herein, we introduce a simple and gram-scale approach for the synthesis of renal-clearable Ta nanodots with high water solubility for CT imaging in vivo. The Ta nanodots, coordination polymers, are fabricated via coordination reactions involving Ta(OH)5, citric acid (CA), and hydrogen peroxide. The Ta nanodots exhibit an ultrasmall hydrodynamic diameter (2.8 nm), high water solubility (1.88 g/mL, 688 mg Ta/mL), superior X-ray absorption capacity, gram-scale production capability (>10 g in lab synthesis), renal-clearable ability, and good biocompatibility. The Ta nanodots possess superior CT imaging efficacy across diverse tube voltages, enabling highly sensitive gastrointestinal CT imaging, renal CT imaging, and CT angiography (CTA). Moreover, Ta nanodots maintain robust CT imaging capabilities even at high X-ray energies, and Ta nanodots-based spectral CT achieves metallic artifacts-minimized CTA. The proposed Ta nanodots present substantial potential as a potent CT imaging probe for diagnosing various diseases.
研究领域:
医学影像学
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材料科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2020
·
IF 3.232
Yanan Zhang,Dajun Hou,Xueli Yu
A ratiometric fluorescent pH sensor was facilely constructed by covalent modification of amino-terminated silicon nanodots (SiND) with pH-sensitive fluorescein isothiocyanate (FITC). After optimization, the SiND-FITC(40:1) material with a SiND:FITC initial mass ratio of 40:1 was selected for the sensing of hydrogen ions. It was observed that the material inherits the unique features of SiND and FITC, and there is significant improvement of SiND acid−base stability, which is a favorable factor in terms of providing fluorescence reference signal. The SiND-FITC(40:1) material displays not only high pH sensitivity, but also good stability and anti-interference ability, and the response process is highly reversible. Deploying the SiND-FITC(40:1) material, we have made available a simple, sensitive, and precise approach for pH sensing. In aqueous solutions, the I 517 /I 466 fluorescence intensity ratio of SiND-FITC(40:1) increases linearly in the pH range of 5.40–7.76. This dual emission nanosensor was successfully applied for pH sensing and cellular fluorescence imaging.
研究领域:
纳米技术
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材料科学
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生物医学工程
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分析化学
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产品关联
DOI
PubMed
高影响因子
BIOELECTROCHEMISTRY
·
2019
·
IF 4.474
Xueyan Li,Xianwen Kan
In this work, a novel electrochemical sensing platform was designed and fabricated by the modification of boronic acid functionalized carbon nanodots (B-CNDs) and poly(thionine) (pTHI) on an electrode surface. B-CNDs can not only accelerate electron transfer but also covalently interact with cis-diol groups of dihydronicotinamide adenine dinucleotide (NADH) through functionalized boronic acid groups. Meanwhile, pTHI served as an inner reference element to provide a built-in correction, which enabled the sensor to detect NADH with high accuracy and reliability based on a ratiometric signal (∆I NADH /∆I THI ). The electrochemical experimental results demonstrated that the ratiometric strategy-based sensor possessed good selectivity and high sensitivity. A linear range of 5.0 × 10 −7 - 2.0 × 10 −4 mol/L for NADH detection was obtained with a limit of detection of 1.5 × 10 −7 mol/L. The sensor has been applied to analyze NADH in human serum samples with satisfactory results. The simple and effective ratiometric strategy reported here can be further used to prepare electrochemical sensors for selective, sensitive, and reliable detection of other cis-diol compounds.
研究领域:
生物化学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF FLUORESCENCE
·
2023
·Vol. 33
·期 4
·1505-1513
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IF 2.7
Wu Sifei,Fang Linxia,Li Yihan,Wang Hai-Bo,Zhang Hongding
Changes in Sn 2+ and glycine levels are relevant to many important physiological procedures in human health. However, investigation of their physiological functions is limited because few versatile methods towards Sn 2+ and glycine detection have been developed. In this work, a fluorescence turn on–off-on strategy was firstly constructed for rapid and sensitive detection of Sn 2+ and glycine through the specific binding between Sn 2+ and glycine. Carbon nanodots (CDs) with a quantum yield of 19.5% were synthesized by utilizing inner film of waste eggshell as carbon source and employed as fluorescent probe. In the presence of Sn 2+ , the fluorescence of CDs was quenched by Sn 2+ via the primary inner filter effect (IFE). However, the binding between Sn 2+ and glycine prevented the IFE between Sn 2+ and CDs, resulting in fluorescence recovery of CDs. Under optimized conditions, the fluorescent response of CDs displayed good linear relationships with the concentrations of Sn 2+ in the range of 10–200 µM and 200–5000 µM, and the limit of detection (LOD) was 2.4 µM. For glycine detection, a good linear relationship was obtained in the concentration range of 5–1000 µM with a low LOD down to 0.76 µM. Moreover, the practicability of the assay was also demonstrated by measuring glycine content in human serum samples. This work provides an economical, green and fast method for biological analysis of Sn 2+ and glycine.
研究领域:
分析化学
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生物医学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Junchao Qin,Yingying Jiao,Mingquan Liu,Yike Li,Jianshe Wang
Heat treatment strategy has been initially used to prepare boron doped graphite carbon nitride nanodots (BCNDs)/carbon-rich g-C 3 N 4 nanosheets (CNS) heterojunction catalysts. The overall procedure involved three stages. First, BCNDs were prepared by the molten salt method. Next, BCNDs were dispersed onto CNS via heat treatment. Finally, the prepared heterojunction catalysts were test for photocatalytic water splitting hydrogen evolution . The experiment results show that the highest photocatalytic hydrogen evolution activity reached 6260.5 µmol·g −1 ·h −1 , which was approximately 15.7, 7.2 and 3.1 folds higher than that of bulk carbon nitride (bulk C 3 N 4 ), CNS and BCNDs/CNS-H prepared by hydrothermal method , respectively. The enhanced photocatalytic performance may be attributed to the synergistic effect of the formation of heterojunction and the increase of C content in carbon nitride. This work provides reliable guideline for the design of a novel and simple method for composite photocatalyst .
研究领域:
材料科学
·
能源科学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Kun Zheng,Xu Li,Mingjun Chen,Yi Gong,Aiwei Tang,Zhenguang Wang,Zhiren Wei,Li Guan,Feng Teng
According to mastery of solvent and reaction temperature, red, yellow, and blue emissive carbon nanodots (CNDs) with high quantum yield are successfully achieved using neutral red carbon source by solvothermal methods. The differences on the emission color of CNDs are evidently ascribed to conjugated absorption bands from n-π* transition confirmed by structural and optical characterizations. The results of quantum yield, transmission electron microscopy images, high magnification fluorescent micrographs of CNDs ethanol solution and solid-state CNDs & polyvinylpyrrolidone (CNDs&PVP) powders reveal that the obtained CNDs possess ultrahigh luminescence, favorable solubility, uniform dispersibility and well material compatibility. The bright fluorescent films were fabricated by mixing the CNDs &PVP composite powders with the epoxy. By taking advantage of these remarkable properties, the red, yellow, blue light-emitting diode was realized by combining CNDs&PVP film with a UV-LED chip. This work provides a new perspective for the explanation of the PL mechanism and the exploration of stable, high-performance, and environment-friendly multicolored CNDs-based LEDs.
研究领域:
材料科学
·
光学工程
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 47
·20806-20811
·
IF 3.288
Dongxiu Wang,Lin Zhang,Pengxia Li,Junfen Li,Chuan Dong
The plant Sophora flavescens Ait was used to prepare carbon nanodots (CDs) which exhibited high fluorescence quantum yield (35.2%). The CDs were remarkably quenched by chromium(VI) (Cr(VI)) and acted as an “on–off” fluorescent probe to realize the real sample detection of Cr(VI) at pH 6.0. The linear range was 0.06–40 μM and the detection limit was 20 nM. In addition, it was found that the fluorescence recovered again when Cr(VI) was redoxed by ascorbic acid (AA), and the recovery degree was linear with the amount of AA from 0.1 to 4.0 mM. With a low detection limit of 80 μM, the system was satisfactorily used to detect AA in several fruits. In conclusion, the proposed “on–off–on” fluorescent probes based on the synthesized CDs were simple, of low-cost and concise for the sequential detection of two targets.
研究领域:
化学
·
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
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