COLLOIDS AND SURFACES B-BIOINTERFACES
·
2016
·
IF 3.902
Yi Zhang,Zhongbing Huang,Zhi Wu,Guangfu Yin,Lei Wang,Fabao Gao
Absence of efficient targeting limits the application of magnetic nanochains (NCs) in the diagnosis of early brain cancer. Herein, dextran-coated NCs (more than 100 nm length and ∼10 nm cores diameter), which were modified by cyclic pentapeptide c(RGDyC) or chlorotoxin (CTX) as the targeting molecules, were fabricated via carbodiimide chemistry and thiol technique. The analysis results revealed that the obtained slender NCs exhibited good biocompatibility, superparamagnetic property, high transverse relaxivity ( R 2 ) and longer blood circulation time. The test results of human umbilical vein endothelial cells and U251 human glioma cells indicated that the conjugation of c(RGDyC) could obviously increase the cyto-internalization of c(RGDyC)-NCs, however, CTX modification could significantly enhance accumulation of CTX-NCs in U251 cells, leading to cellular apoptosis. The results of in vivo biodistribution tests and in vivo magnetic resonance (MR) imaging indicated that, although the c(RGDyC)-NCs could target early glioma to some extent and obviously enhance the contrast of MR imaging, CTX-NCs possessed higher tumor-targeting ability and good inhibition effect than the c(RGDyC)-NCs, suggesting that CTX-NCs are promising candidates for the diagnosis and therapy of early glioma.
研究领域:
生物医学工程
·
肿瘤学
·
分子影像学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
·
2025
·
IF 3.1
Zhifan Li,Huiwei Wei,Gentao Gao,Zhiyong Deng,Shaohua Sun,Zuoye Liu,Baowei Ding,Bitao Hu,Jie Shen
This study represents a highly sensitive approach of determination of lanthanides by nanochain enhanced laser induced breakdown spectroscopy (LIBS). Owing to geometrical characteristics of the nanochains, the hotspot in the gap between Ag NPs in nanochains offered an intense plasmonic field for the LIBS signal enhancement. Remarkably, the nanochain enhanced LIBS for determining Ce and La element yielded outstanding limit of detection (LOD): 27.47 and 85.71 ng/mL, respectively, indicating that the nanochain configuration exhibited enhanced LIBS signal response. The preponderant performances of the well-aligned nanoparticle sensor in elemental analysis open up its possibilities for nanochain enhanced LIBS in sensitive elemental detection.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Electrochemical Science
·
2024
·
IF 1.3
Yuning Qu,Ying Sun,Ming Song,Hao Wang,Ningru Xiao
An efficacious strategy to enhance the activity and stability of electrocatalysts for alcohol oxidation reactions is the formation of alloys of palladium with oxygenophilic metals. In this study, Palladium nano chains with an average diameter of approximately 4.4 nm were synthesized via a one-step hydrothermal approach, employing creatine as the structural guide. The one-dimensional structure yielded a huge electrochemically active area (84.5 m 2 g −1 ) and good electrical conductivity. the mass activity of Pd 87 Au 13 NCs for alkaline ethanol oxidation reaction was 4050 mA mg Pd+Au −1 , which is 7.32 times higher thancommercial Pd/C, and also maintains a high residual current density after 20000 s stability test. In addition, the excellent performance of the material was demonstrated during the oxidation of ethylene glycol and glycerol. The improved catalytic performance is owed to the interconnected chain shape providing fast electron transport channels, and the Au doping not only optimizes the electronic structure of Pd but also has a bifunctional effect, which effectively removes the carbon-containing intermediates generated by Pd during alcohol oxidation, thus improving its resistance to poisoning and stability.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 14
·19284-19296
·
IF 2.478
Li Sirui,Zhao Hongwei,Wang He,Zhu Hang,Zhang Hehan,Yu Haitao,Yang Tianye
At present, functional materials such as metal sulfides, metal oxides and so on synthesized with metal–organic frameworks (MOFs) as the general templates or precursors in the field of gas sensing have been a new strategy to improve gas-sensing performance. In this work, a unique MOF-5-derived ZnO nanochains (NCs) sample is synthesized through a conventional solvothermal method with subsequent annealing process. The ZnO NCs-based sensor exhibits outstanding sensing performance such as fast response time (< 1 s) and high response value 34.7 toward 20 ppm triethylamine (TEA). The ZnO NCs sample was characterized by a series of methods (XRD, SEM, XPS and so on). The excellent TEA-sensing properties can be ascribed to the unique nanochain morphology and a plenty of oxygen vacancies of the ZnO crystal through the analysis of the morphology and composition of the sample. In addition, a possible growth mechanism comes up and the sensing mechanism is discussed. The superior TEA sensing performance makes the as-synthesized MOF-5 derived ZnO NCs sample a potential candidate for TEA fast detection.
研究领域:
材料科学
·
化学传感器
·
纳米材料合成
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Luyang Liang,Gaojie Han,Yang Li,Biao Zhao,Bing Zhou,Yuezhan Feng,Jianmin Ma,Yaming Wang,Rui Zhang,Chuntai Liu
Electromagnetic (EM) pollution affecting people’s normal lives and health has attracted considerable attention in the current society. In this work, a promising EM wave absorption and shielding material, MXene/Ni hybrid, composed of one-dimensional Ni nanochains and two-dimensional Ti3C2Tx nanosheets (MXene), is successfully designed and developed. As expected, excellent EM wave absorption and shielding properties are obtained and controlled by only adjusting the MXene content in the hybrid. A minimum reflection loss of −49.9 dB is obtained only with a thickness of 1.75 mm at 11.9 GHz when the MXene content is 10 wt %. Upon further increasing the MXene content to 50 wt %, the optimal EM shielding effectiveness (SE) reaches 66.4 dB with an absorption effectiveness (SEA) of 59.9 dB. Mechanism analysis reveals that the excellent EM wave absorption and shielding performances of the hybrid are contributed to the synergistic effect of conductive MXene and magnetic Ni chains, by which, the dielectric properties and electromagnetic loss can be easily controlled to obtain appropriate impedance matching conditions and good EM wave dissipation ability. This work provides a simple but effective route to develop MXene-based EM wave absorption and shielding materials. A universal guideline for designing the absorbing and shielding materials for the future is also proposed.
研究领域:
材料科学
·
电磁学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Bo Dai,Yong Ma,Shixuan Feng,Haowen Wang,Mingliang Ma,Jianxu Ding,Xunqian Yin,Tingxi Li
The development of microwave absorbing materials with strong absorption capacity, wide bandwidth and light weight has always been a topic of concern. Herein, one-dimensional (1D) M (Co, Ni)@polyaniline (PANI) nanochains (NCs) with adjustable thickness have been successfully synthesized by reducing the mental ions under a parallel magnetic field, pretreating metal nanochains with KH550 and pre-oxidization of aniline monomer. It is found that Co has a more favorable absorption width for electromagnetic waves (EMW) and Ni aims at the absorption intensity. Furthermore, the effect of metal elements on adjusting impedance matching is more significant than their magnetic loss for composites. The minimum reflection loss (RLmin) of CoP2 can be up to −73.16 dB at 4.63 mm and the effective absorption bandwidth (EAB) is 4.98 GHz at 2.17 mm, while those of NiP2 are −65.06 dB at 3.88 mm and 5.02 GHz at 2.05 mm. The increase of PANI content can significantly reduce the matching thickness. And the RLmin of CoP3 and NiP3 can reach −58.72 dB at 2.32 mm and −65.96 dB at 1.59 mm, respectively. The absorption mechanism reveals that the matching thickness of the quarter-wavelength determines frequency location. And high absorption intensity is attributed to the synergistic effects of impedance matching, conduction loss, polarization loss, and magnetic loss. This work provides a theoretical basis for designing PANI or other conducting polymers coating magnetic nanochains for electromagnetic absorbing materials with strong absorption capacity, wide bandwidth and light weight.
研究领域:
材料科学
·
电磁学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2023
·
IF 6.8
Fengxia Chang,Kai Ren,Sijing Li,Qianqian Su,Jiangping Peng,Jiong Tan
Gold nanochains (AuNCs) were prepared, and this novel material was combined with carboxylated multi-walled carbon nanotubes (cMWCNTs) to be a nanocomposite for the first time. The transmission electron microscopy (TEM), scanning electron microscope (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD) and UV-Vis spectra were used to characterize the successful preparation of AuNCs and AuNC-cMWCNT composite. Based on this hybrid material, a voltammetric sensor of bisphenol A (BPA) was established. The proposed sensor displayed excellent performance for the measurement of BPA by obvious decreased anodic peak potential and enlarged peak current. Using the optimized conditions, BPA was detected using linear sweep voltammetry, and the linear range showed as wide as 0.5 μM to 2000 μM with the detection limit estimated to be 12 nM (S/N = 3). The as-proposed sensor also exhibited satisfactory performance in determining BPA of actual plastic samples.
研究领域:
分析化学
·
环境科学
·
纳米材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CELL PROLIFERATION
·
2018
·Vol. 51
·期 6
·e12486
·
IF 4.936
Yuedi Yang,Zhongbing Huang,Ximing Pu,Guangfu Yin,Lei Wang,Fabao Gao
Objective Five-year survival rate at early lung tumour was about 70%; however, its early diagnosis rate was still at a low level, so the enhancement of diagnosis level for early lung tumour is the key factor to increase the survival rate. Diagnosis and therapy of early lung tumour are still challenged. Methods The magnetic nanochains (NCs) with biocompatibility and transverse relaxivity (r 2 = 231 Fe mmol l −1 s −1 ) were fabricated through a co-precipitation method in the assistance of dextran, and then, linked with chlorotoxin (CTX) and curcumin (Cur) via the PEGylation and carbodiimide technique (named as CTX-NCs-Cur). Results The results of cell test indicated that CTX-conjugated NCs could obviously target non–small-cell lung cancer cells and limit their growth. The in vivo results of magnetic resonance imaging and fluorescence imaging indicated that the CTX-NCs-Cur significantly targeted the tumour site and enhanced images contrast of the small-size tumour. Moreover, the results of everyday tail-vein injection confirmed that CTX-NCs-Cur could significantly limit the growth of early tumour, due to blocking Cl ion channels from CTX-NCs-Cur-MMP-2 composite and intracellular ROS increase from Cur treatment. Conclusions We provided a mechanism about the effect of CTX-NCs-Cur on the targeting and limiting early tumour, and these results indicated the application foreground of CTX-NCs-Cur in tumour diagnosis and therapy.
研究领域:
生物医学工程
·
纳米医学
·
肿瘤学
✓ 已验证
DOI
PubMed
高影响因子
Biomaterials Research
·
2022
·Vol. 26
·期 1
·1-13
·
IF 15.863
Shuai Cijun,Chen Xuan,He Chongxian,Qian Guowen,Shuai Yang,Peng Shuping,Deng Youwen,Yang Wenjing
Background Fe 3 O 4 nanoparticles are highly desired for constructing endogenous magnetic microenvironment in scaffold to accelerate bone regeneration due to their superior magnetism. However, their random arrangement easily leads to mutual consumption of magnetic poles, thereby weakening the magnetic stimulation effect. Methods In this study, magnetic nanochains are synthesized by magnetic-field-guided interface co-assembly of Fe 3 O 4 nanoparticles. In detail, multiple Fe 3 O 4 nanoparticles are aligned along the direction of magnetic force lines and are connected in series to form nanochain structures under an external magnetic field. Subsequently, the nanochain structures are covered and fixed by depositing a thin layer of silica (SiO 2 ), and consequently forming linear magnetic nanochains (Fe 3 O 4 @SiO 2 ). The Fe 3 O 4 @SiO 2 nanochains are then incorporated into poly l-lactic acid (PLLA) scaffold prepared by selective laser sintering technology. Results The results show that the Fe 3 O 4 @SiO 2 nanochains with unique core–shell structure are successfully constructed. Meanwhile, the orderly assembly of nanoparticles in the Fe 3 O 4 @SiO 2 nanochains enable to form magnetic energy coupling and obtain a highly magnetic micro-field. The in vitro tests indicate that the PLLA/Fe 3 O 4 @SiO 2 scaffolds exhibit superior capacity in enhancing cell activity, improving osteogenesis-related gene expressions, and inducing cell mineralization compared with PLLA and PLLA/Fe 3 O 4 scaffolds. Conclusion In short, the Fe 3 O 4 @SiO 2 nanochains endow scaffolds with good magnetism and cytocompatibility, which have great potential in accelerating bone repair.
研究领域:
材料科学
·
生物材料
·
组织工程
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Jianing Li,Xuegang Lu,Yin Zhang,Fei Cheng,Yanlin Li,Xiaoxiang Wen,Sen Yang
Smart optical materials are drawing more and more attention because of their wide application in energy conservation, wearable sensors, optical tuning, and medical devices. However, current smart optical materials, including electroresponsive, thermoresponsive, and mechanoresponsive materials, are greatly restricted in practical applications because of their long response time, complicated preparation, and high cost. This study develops a novel, magnetically tunable, smart optical material with swift and high-contrast optical switching based on one-dimensional (1D) Fe3O4@SiO2 nanochains (NCs), which have the large shape anisotropy of the 1D structure and the superparamagnetic properties of Fe3O4 particles. The material exhibited a clear transparent state when NCs were arranged parallel to the viewing direction under an applied magnetic field, whereas it showed good shielding effect when the NCs were randomly oriented upon removal of the field. The light transmittance could be dynamically adjusted over the wide range of 20–80% through a small applied magnetic field of 50–100 Oe, which is superior to most of the currently reported systems. This swift, sensitive, and reversible response is attributed to the good responsivity of magnetic NCs. Also, an effective model was proposed to explain the transmittance modulation scheme and forecast its optical potential. The large tunable range and the low triggered field make Fe3O4@SiO2 NCs an advantageous candidate for application in smart windows, optical switchers, and other fields.
研究领域:
材料科学
·
光学工程
✓ 已验证
DOI
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 11
·964
·
IF 4.4
Gongpu Shi,Luying Si,Jinyang Cai,Hao Jiang,Yun Liu,Wei Luo,Huiru Ma,Jianguo Guan
Diabetes is a common disease that seriously endangers human health. Continuous glucose monitoring (CGM) is important for the prevention and treatment of diabetes. Glucose-sensing photonic nanochains (PNCs) have the advantages of naked-eye colorimetric readouts, short response time and noninvasive detection of diabetes, showing immense potential in CGM systems. However, the developed PNCs cannot disperse in physiological environment at the pH of 7.4 because of their poor hydrophilicity. In this study, we report a new kind of PNCs that can continuously and reversibly detect the concentration of glucose (Cg) in physiological environment at the pH of 7.4. Polyacrylic acid (PAA) added to the preparation of PNCs forms hydrogen bonds with polyvinylpyrrolidone (PVP) in Fe3O4@PVP colloidal nanoparticles and the hydrophilic monomerN-2-hydroxyethyl acrylamide (HEAAm), which increases the content of PHEAAm in the polymer shell of prepared PNCs. Moreover, 4-(2-acrylamidoethylcarbamoyl)-3-fluorophenylboronic acid (AFPBA), with a relatively low pKa value, is used as the glucose-sensing monomer to further improve the hydrophilicity and glucose-sensing performances of PNCs. The obtained Fe3O4@(PVP-PAA)@poly(AFPBA-co-HEAAm) PNCs disperse in artificial serum and change color from yellow-green to red when Cgincreases from 3.9 mM to 11.4 mM, showing application potential for straightforward CGM.
研究领域:
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CRYSTAL RESEARCH AND TECHNOLOGY
·
2018
·Vol. 53
·期 9
·1800095
·
IF 1.122
Jingru Zhao,Ming Yang
Self-assembly represents an energy-efficient way toward the configurable design of functional nanomaterials. In this paper, triangular silver nanoplates are shown to spontaneously form anisotropic assemblies in the solution. Nanochains consisting of face-to-face aligned nanoplates can reach hundreds of nanometers long after the dispersion of triangular silver nanoplates is allowed to age at room temperature for 1 week. The preferred face-to-face attachment is attributed to the maximized van der Waals attraction for a thermodynamically stable configuration as opposed to side-by-side attachment. Time-dependent UV–vis spectra show a gradual blue-shift along with the increase of aging time, indicating a likely stepwise growth of nanochains. The peak shift is however found to be much smaller than the results of finite-difference time-domain simulations based on the same sized nanoplates with ideally concentric face-to-face placement. Such discrepancy may be attributed to the possible misalignment and size variations of stacking nanoplates.
研究领域:
纳米材料
·
物理化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）