Antimicrobial Activity of Nano-GeO2/CTAB Complex Against Fungi and Bacteria Isolated from Paper
Microbial attack, particularly fungal degradation of cellulose, is a leading cause of paper damage. To address fungal spores and the rising concern of microbial drug resistance, a nano-Germanium dioxide (GeO2)/cetyltrimethylammonium bromide (CTAB) complex (nano-GeO2/CTAB complex) with potent antibacterial properties was synthesized. Its inhibitory effects were evaluated against bacteria, including Gram-positiveStaphylococcus aureusand Gram-negativeEscherichia coli, as well as fungi isolated from paper (Fusariumspp.,Aspergillusspp., andPenicillium citrinum). The nano-GeO2/CTAB complex exhibited significant (p< 0.05) inhibitory effects againstS. aureusandE. coli. Moreover, a 60 min treatment with 1 mg/mL of the complex significantly inhibited the growth of all tested fungi and reduced their biomass after five days of culture, while 4 mg/mL completely deactivated spores. Filter paper pre-treated with the nano-GeO2/CTAB complex showed complete resistance to microbial attack, exhibiting no fungal growth and a clear inhibition zone devoid of bacterial growth. In contrast, untreated controls displayed fungal coverage exceeding 95% within five days. These findings highlight the nano-GeO2/CTAB complex as a promising antimicrobial agent for protecting paper materials from microbial degradation.
危险品化学品经营许可证（带存储）