MOLECULES
·
2022
·Vol. 27
·期 23
·8437
·
IF 4.927
Rongfei Lu,Jianwei Xu,Zhen Wang,Shaoyong Zhang,Hailong Wang,Hui Xu,Min Lv
Due to the extensive use of agrochemicals resulting in the emergence of pesticide resistance and ecological environment problems, the research and development of new alternatives for crop protection is highly desirable. In order to discover potent natural product-based insecticide candidates, a series of new cholesterol ester derivatives containing cinnamic acid-like fragments at the C-7 position were synthesized. Some derivatives showed potent pesticidal activities. AgainstMythimna separataWalker, compounds2a,Id,Ig, andIIgshowed 2.1–2.4-fold growth-inhibitory activity of the precursor cholesterol. AgainstPlutella xylostellaLinnaeus, compoundsIg,IIf, andIIiexhibited 1.9–2.1-fold insecticidal activity of cholesterol. These results will pave the way for the future synthesis of cholesterol-based derivatives as agrochemicals.Keywords:cholesterol;cinnamic acid;structural modification;agricultural activity
研究领域:
植物保护
·
有机化学
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产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Yifan Li,Weichun Pan,Zhihui Feng,Feina Gu,Jianxin Chen,Fang Wang,Jieqiong Wang,Mingming Zhang,Chunmei Li,David Julian McClements,Junfeng Yin
Keemun tea infusion was selected as a model system under various centrifugation speeds to build a relationship among chemical composition, properties of nanoparticles in tea infusion (Tea-NPs), and tea tastes via chemical analyses, sensory evaluation, and light scattering techniques. The research results showed that the hydrodynamic radius ( R h ) of the Tea-NPs in the black tea infusion ranged from 100 to 250 nm, with a negative charge (-10 to -13 mV). The gyration radius ( R g ) and zeta-potential assessments elucidated that Tea-NPs underwent structural modifications, which altered their size, shape, and compactness. High-speed centrifugation caused the dissolution of components such as polysaccharides in the Tea-NPs, and changes in the particle compactness and aggregation altered the structure of the Tea-NPs, resulting in an increase in R h , while reducing the bitterness and enhancing the overall flavor of the tea infusion. This study highlights the important role of Tea-NPs in tea quality evaluation and their potential to drive innovative methods for improving tea product quality.
研究领域:
食品科学
·
茶学
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2021
·
IF 8.071
Tao Huang,Zhiyu Su,Yuxing Dai,Lulu Zhou
The influence of intercalated anions on the structure and composition of green rusts supplies a theoretical possibility for the investigation of the structural modification of Fe II /Fe III (oxyhydr)oxide materials. β-Cyclodextrin was intercalated into the mixed-valent iron-based hydroxide layers to synthesize new green rust materials (β-CD GRs), pursuing high-capacity uranium VI (U VI ) sorption . The molar ratios of Fe II to Fe III and the molar ratios of β-CD GR to Fe II + Fe III had a significant effect on the synthesis of β-CD GRs. The synthesis process was further optimized by the quadric predictor and desirability function in a central composite design in combination. Both strong acidity and alkalinity were harmful to the adsorption of β-CD GRs towards U VI . The pseudo-first-order kinetic model and Langmuir isotherm model were appropriate in fitting the whole adsorption process. The maximum monolayer adsorption capacity of β-CD GRs was 2548.61 mg/g. The presence of mimic groundwater constituents explicitly deteriorated the interaction between β-CD GR and U VI species. Nanoscale nodules and particles were formed on the β-CD GR after the adsorption experiments. The peaks at 1159 and 609 cm −1 vanished with the band at 1103 cm −1 being left-shifted to 1117 cm −1 in the FTIR spectra of β-CD GR during the heterogeneous process. The intercalation of β-CD brought obvious enhancement of U VI species sorption to the GR material, which was combinedly driven by several reaction pathways and different from the unmodified GRs.
研究领域:
环境科学
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材料化学
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产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Weiwei Hu,Junchao Gu,Kai Yang,Zhiguo Zhang,Daqun Liu,Weicheng Wu
Thermal processing is inevitable during highland barley (HB) production, but few studies pay attention to the component changes and their impact on HB properties. This study explored the different thermal effects of HB on the molecular, structural and physicochemical properties of β-glucan, as well as the related ultrastructural properties of kernels and the nutritional properties of HB flour (HBF). Microstructure images illustrated that thermal treatment dramatically disrupted endosperm cell walls, roughening their surfaces and almost gelatinised the starch granules of the HB kernel. The molecular weight and polydispersity index of β-glucan decreased from 253.10 ± 0.05 × 10 4 g/mol to 9.68 ± 0.03 × 10 4 g/mol and 13.64 ± 0.08 to 1.66 ± 0.04, respectively. X-ray diffraction and infrared spectroscopy demonstrated that thermal processing resulted in the breaking of polymer chains in β-glucan, but its main functional groups remained unchanged. Structural modifications in β-glucan led to reduced thermal stability and lower G′ and G″ values, indicating weaker gel structures. Heat treatment increased the peak viscosity of 100-5-HBF and 150-5-HBF, while reducing it in 150-50-HBF and 200-5-HBF due to the effects of starch gelatinisation and depolymerisation. Meanwhile, higher pasting viscosity and much slower starch digestion were apparent in the HBF than in the HBF-non β-glucan system. The results indicated the structural disruption of endosperm cell walls enhanced component interactions, which was also evidenced by varying β-glucan release rates during initial digestion (20 min). Thus, controlled thermal processing that minimally disrupts cellular structures or forms starch-encapsulating complexes may produce β-glucan-rich products with reduced starch digestibility.
研究领域:
食品科学
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植物化学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2020
·
IF 6.785
Xue Zhao,Gang Wu,Wenpeng Zhang,Mengqiu Dong,Yu Xia
Sphingomyelins (SMs) are an essential class of lipids widely existing in different organisms. The sphingoid base and N-acyl chain are two building blocks which can undergo different types of modifications during lipogenesis, including desaturation, hydroxylation, and methyl branching. Current lipidomic analysis methods cannot provide detailed information on these structural motifs. Herein, we developed a tandem mass spectrometric method by harnessing radical-directed dissociation (RDD) from collision-induced dissociation (CID) of the bicarbonate anion adduct of SM ([M + HCO3]−). A major RDD channel produced a high-abundance fragment carrying the intact N-acyl chain, termed as “N-acyl fragment”, allowing the assignment of the sphingoid base/N-acyl composition and relative quantitation of compositional isomers of SM at high sensitivity. RDD also produced intrachain fragments in lower abundances, which helped localization of methyl branching and hydroxylation in SM. The acetone Paternò–Büchi (PB) reaction was found to be capable of derivatizing the Δ4 carbon–carbon double bond (C═C) in sphingosine (SPH) base and producing C═C diagnostic ions upon CID, albeit at much lower efficiencies than those of the isolated C═C in alkyl chains. A liquid chromatography–mass spectrometry workflow was developed by incorporating MS2 CID of SM via [M + HCO3]− and PB-MS2 CID. The capability of profiling SM with detailed structural information was demonstrated by analyzing complex lipid extracts from porcine brain and Caenorhabditis elegans. These results provided visualization of the sphingoid base/N-acyl compositional isomers of SM lipids and revealed large structural diversity from each sample. These included identification of the sphingadiene base [d18:1(Δ4,14)], C═C location isomers in N-acyls, C-2 hydroxylation of N-acyls, and iso-methyl branched SPH base.
研究领域:
生物化学
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脂质组学
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分析化学
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产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Yongniu Zhang,Shuangfei Wang,Debao Niu,Zhi Huang,Lili Gai,Fangxue Hang
Casein is the primary allergen in the dairy products. This study investigated the effects of moderate dielectric barrier discharge (DBD) plasma treatment on the structure, antigenicity, and digestibility of casein. The results showed that exposure to moderate DBD plasma for 4 min decreased the antigenicity, digestibility, total amino acid content, α-helix content, surface hydrophobicity, and total free sulfhydryl (SH) groups of casein by 18.2%, 9.5%, 42.2%, 4.5%, 51.0%, and 50.9%, respectively. The amino acid side chains of casein were oxidized, but cleavage was not observed on the peptide bone. Moderate DBD plasma treatment induced structural modification and oxidation of the amino acid side chains, which disrupted both the conformational and linear epitopes of casein, resulting in a reduction of its antigenicity. The modification of amino acid may have also disrupted the enzymatic cleavage site of casein, leading to a decrease in its digestibility. This study provides evidence that moderate DBD plasma treatment can decrease the antigenicity of casein, potentially broadening the application of dairy products in the food industry.
研究领域:
食品科学
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生物化学
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产品关联
DOI
高影响因子
RSC Advances
·
2024
·Vol. 14
·期 39
·28320-28331
·
IF 3.9
Linjie Yi,Hongwei Wang,Xianliang Ren,GaoBin Liu,Hongen Nian,Zhiqin Zheng,Fang Wu
Structural modification is expected to be a facile way to enhance the adsorption performance of MXene. In this work, the structural modification of Ti3C2Tx was carried out by a spray freezing method, and two kinds of nano-structure (spherical and flaky) of Ti3C2Tx were prepared by adjusting the solution concentration of Ti3C2Tx. Then the Cr(VI) adsorption capacity and removal efficiency of the spherical and flaky Ti3C2Tx was investigated, respectively. It is found that flaky Ti3C2Tx was produced with a Ti3C2Tx concentration of 3 mg mL−1, while spherical Ti3C2Tx was obtained with a concentration of 6 mg mL−1. The long diameter of flaky Ti3C2Tx is about 8–10 μm, and the specific surface area is 17.81 m2 g−1. While spherical Ti3C2Tx had a diameter of about 1–4 μm and a specific surface area of 17.07 m2 g−1. The optimized structure of flaky and spherical Ti3C2Tx improves the maximum adsorption capacity by 97% and 33%, respectively, compared with the few-layer Ti3C2Tx. The maximum adsorption capacity of flaky Ti3C2Tx was 928 mg g−1, while that of spherical Ti3C2Tx was 626 mg g−1. The adsorption capacity of both Ti3C2Tx structures decreased with the increase of pH, and reached the maximum value at pH = 2; meanwhile, the adsorption capacity of both Ti3C2Tx structures increased with the increase of Cr(VI) concentration. The adsorption of Cr(VI) on flaky Ti3C2Tx was very fast, reaching equilibrium in 3 min, while spherical Ti3C2Tx took 5 min. The adsorption of Cr(VI) on both Ti3C2Tx structures belonged to the monolayers, heat-absorbing chemical adsorption, and the diffusion process of Cr(VI) was regulated by the external diffusion and internal diffusion of particles. Its adsorption mechanism was the combination of reductive adsorption and electrostatic adsorption.
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Water Research X
·
2025
·
IF 8.2
Hong Tu,Bihong Tian,Zhichao Zhao,Renjiang Guo,Ya Wang,Shunhong Chen,Jian Wu
The structural modulation of pristine graphitic carbon nitride poses a considerable challenge in the rational design of catalysts for the efficient degradation of small organic pollutants under visible light. In this study, we combined first-principles calculations and the structure-function relationship to predict a high-performance catalyst. The results reveal that CN-8 demonstrates a remarkable degree of electron-hole separation. Notably, CN-8 shows exceptional degradation efficiency towards rhodamine B, tetracycline, bisphenol A, and fluralaner under visible light irradiation. Specifically, the degradation rate constants are 11, 4, 12, and 32 times higher, respectively, compared to bulk g-C 3 N 4 . Through density functional theory calculations and investigations of the structure-function relationship, it is confirmed that the superior catalytic activity of CN-8 lies in modifying the amino position, which alters the electron cloud distribution and promotes the efficient separation of photo-generated electron-hole pairs. This study provides valuable insights for the development of eco-friendly and efficient photocatalysts for environmental remediation.
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
·
2018
·Vol. 94
·期 3
·785-794
·
IF 2.587
Yuanchun Zhang,Qian Zhang,Zhengyu Dong,Liying Wu,Junming Hong
BACKGROUND Iron (Fe)–copper (Cu) bimetallic catalysts such as CuFe 2 O 4 , CuFeO 2 and CuO/Fe 3 O 4 have been widely applied in persulfate oxidization process. Among these catalysts, CuFe 2 O 4 has shown excellent performance in catalyzing peroxymonosulfate. However, because the catalytic effect of CuFe 2 O 4 on persulfate (PS) is not obvious, the application of CuFe 2 O 4 to activate persulfate has been investigated only rarely. Hence, structural modification has been applied in order to improve the catalytic activity of CuFe 2 O 4 on persulfate. RESULT In this study, Oxygen (O)-deficient CuFe 2 O 4 was synthesized via the hydrogen reduction method and first used to activate PS for degrading acetaminophen (APAP) in aqueous solution with low catalyst concentration of 0.3 g L −1 . Results reveal that high-concentration APAP (100 mg L −1 ) could be efficiently removed by O-deficient CuFe 2 O 4 -activated PS, and 91% removal rate could be reached in 60 min using 0.8 g L −1 PS and 0.3 g L −1 catalyst under unadjusted pH. Dissolved O 2 and Cl − showed inhibitory effects on the degradation process. Radical scavenger experiments, in which methanol, tert -butyl alcohol (TBA) and nitrobenzene (NB) were used as radical trappers, indicated that SO 4 − and OH were the active radicals in the reaction, but the main radical was SO 4 − . Oxygen-deficient CuFe 2 O 4 showed strong reduction ability and could activate PS efficiently, and the electron transfer capability was remarkably enhanced after this structural modification. CONCLUSIONS Results indicated that compared to the pristine crystal, the catalytic activity of CuFe 2 O 4 could be improved through structural modification. Additionally, the structurally modified catalyst showed high potential to treat wastewater with high antibiotic content under mild conditions. © 2018 Society of Chemical Industry
研究领域:
环境科学
·
催化化学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2023
·
IF 8.8
Jie Yang,Luqiang Liu,Yiping Ren,Lunan Guo,Ying Chen,Jian-Ya Qian
The impacts of intensity and treating time of alternating current (AC) electric field (EF) on structure and volatile compounds of peanut protein were investigated for low denaturation. The secondary and tertiary structures, polar and weakly polar volatiles were characterized qualitatively and quantitatively using ultraviolet and fluorescence photospectrometry, free sulfhydryl and disulfide groups determination, and combination of gas chromatography and mass spectrometry. The results showed that the ACEF affected significantly proportions of α-helices, β-sheets, β-turns, and random coils as evidenced by Fourier transform infrared spectrometry. Blue shifts of UV and fluorescence spectra, increased surface hydrophobicity and disulfide bonds could be observed after ACEF treatments. The DB-WAX and DB-5MS columns for the polar and weakly polar volatile compound separation revealed that ACEF caused either disappearance or emerging of volatile compounds. The PCA demonstrated that the two principal components contributed about 70 % or more to the flavor and PLS-DA discriminated 18 key compounds.
研究领域:
食品科学
·
化学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ADVANCED MATERIALS
·
2024
·
IF 27.4
Xiangsi Liu,Chen Yuan,Xingyu Zheng,Gangya Cheng,Hui Qian,Bizhu Zheng,Xingyu Lu,Yao Yang,Yizhou Zhu,Yuxuan Xiang
Layered sodium-ion oxides hold considerable promise in achieving high-performance sodium-ion batteries. However, the notorious phase transformation during charging, attributed to increased O 2− ─O 2− repulsion, results in substantial performance decay. Here, a hierarchical layer modification strategy is proposed to stabilize interlayer repulsion. During desodiation, migrated Li + from the transition metal layer and anchored Ca 2+ in sodium sites maintain the cationic content within the sodium layer. Meanwhile, partial oxygen substitution by fluorine and the involvement of oxygen in redox reactions increase the average valence of the oxygen layer. This sustained cation presence and elevated anion valence collectively mitigate increasing O 2− ─O 2− repulsion during sodium extraction, enabling the Na 0.61 Ca 0.05 [Li 0.1 Ni 0.23 Mn 0.67 ]O 1.95 F 0.05 (NCLNMOF) cathode to retain a pure P2-type structure across a wide voltage range. Unexpected insights reveal the interplay between different doping elements: the robust Li─F bonds and Ca 2+ steric effects suppressing Li + loss. The NCLNMOF electrode exhibits 82.5% capacity retention after 1000 cycles and a high-rate capability of 94 mAh g −1 at 1600 mA g −1 , demonstrating the efficacy of hierarchical layer modification for high-performance layered oxide cathodes.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
CHEMISTRY & BIODIVERSITY
·
2022
·Vol. 19
·期 4
·e202101039
·
IF 2.745
Zhiping Che,Yuanhao Li,Xiaolong Guo,Jiaxuan He,Song Zhang,Lina Zhu,Yibo Liu,Ruxue Wei,Yingjun Yang,Xiaobo Huang,Shengming Liu,Genqiang Chen,Yuee Tian
In order to discover highly active fungicides, sixteen novel sulfonate derivatives of Fenjuntong were synthesized by structural modification of 2′-hydroxybutyrophenone, and their anti-oomycete activity against Phytophthora capsici Leonian was determined in this study. Among all tested compounds, compound 3b displayed more significant anti-oomycete activity than the precursor Fenjuntong against P. capsici , and the EC 50 values of 3b and Fenjuntong were 84.50 and 517.25 mg/L, respectively. By comparing the anti-oomycete activity of compounds 3a – p , I-a – p , and II-a – p , the following conclusions were drawn: (1) Hydroxy group is well tolerated, and sulfonylation of hydroxy group enhances its anti-oomycete activity. (2) The proper length of the ketone carbonyl chain is very important for their anti-oomycete activity. (3) The presence of a site methoxy group in the structural skeleton is closely related to the anti-oomycete activity. These important results will pave the way for further modification of Fenjuntong to develop potential new fungicides. Graphical
研究领域:
农药化学
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植物病理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）