MOLECULES
·
2022
·Vol. 27
·期 7
·2119
·
IF 4.927
Xue-Li Liu,Yi-Fan Chen,Jing-Jing Yang,Si-Jin Li,Hua-Le Xie,Tian-Lin Ma
A new type of hydroxyalkyl starch, γ-hydroxypropyl starch (γ-HPS), was prepared by etherification of alkali-activated starch with 3-chloropropanol. The reaction efficiency, morphological change, thermodynamic and apparent viscosity properties, and other physicochemical characteristics were described. The molar substitution (MS) of modified whole starch was determined to be 0.008, 0.017, 0.053, 0.106, and 0.178, with a ratio of 5%, 15%, 25%, 35%, and 45% 3-chloropropanol to starch (v/w), respectively. Compared to native starch, the granular size and shape and the X-ray diffraction pattern of γ-HPS are not very different. For low-substituted γ-HPS, the implications may be less evident. Thermal stability measurements by means of thermogravimetric analyses and differential scanning calorimetry (TGA-DSC) proved that thermal stability was reduced and water retaining capacity was increased after hydroxypropylation. Furthermore, the findings also showed that the solubility, light transmittance, and retrogradation of γ-HPS pastes could be improved by etherification. The greater the MS of the γ-HPS, the more its freeze–thaw stability and acid resistivity increased. In this study, we provide relevant information for the application of γ-HPS in food and non-food industries.Keywords:γ-hydroxypropyl starch;molar substitution;physicochemical properties
研究领域:
食品科学
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Yihui Wang,Qing Liu,Yueyue Yang,Chao Qiu,Aiquan Jiao,Zhengyu Jin
Improving the mechanical and 3D printing performance of pea protein (PeaP) hydrogels contributes to the development of innovative plant-based gel products. Herein, we proposed a strategy for constructing PeaP–hydroxypropyl starch (HPS) interpenetrating network hydrogels, in which the structure, strength, and 3D printing properties of the hydrogels were regulated by changing pH. Results showed that pH significantly affected the gelation process of PeaP/HPS hydrogels. The hydrogels formed a lamellar structure at pH 3, a granule aggregation network structure at pH 5, porous structures at pH 7 and 9, and a honeycomb structure at pH 11. The strength of hydrogels formed at different pH values had the following order: pH 3 ＞pH 11 ＞ pH 7 ＞pH 9 ＞pH 5. The storage modulus (G') of the hydrogel at pH 3 was up to 4149 Pa, but only 695 Pa at pH 5. Moreover, hydrogel at pH 3 had the best self-recovery of 55%. 3D printed objects from gel inks at pH 3 exhibited high structural integrity and fidelity at 60 °C. Gelling force analysis indicated hydrogen bonds were the dominant interaction within all hydrogels. Overall, this study suggested that PeaP/HPS hydrogel formed at pH 3 possessed the most excellent mechanical properties and 3D printing capabilities, which may provide insights into the development of novel PeaP-based gel food ingredients and promote the application of PeaP in the food industry.
研究领域:
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Xuedi Ma,Zheng Zhang,Zhao Li,Zhengzong Wu,Lu Lu,Katsuyoshi Nishinari,Meng Zhao,Bo Cui
The impact of phase separation behavior on the performance of hydrogels has always been the research focus. This study explored the relationship of “pH-microstructure-hydrogel properties” of phase-separated hydrogels composed of type-A gelatin (GE, 5 wt%) and hydroxypropyl starch (HPS, 3 wt%). The results revealed that changes in the microstructure of the hydrogel at different pHs significantly impacted the gel properties. At pH 4.00 and 11.00, phase separation occurred in the GE/HPS gel with a microstructure of HPS-in-GE. In particular, at pH 5.00, 6.00, 7.00, and 9.00, severe phase separation resulted in the separation of substantial aggregates of HPS and GE, resulting in a continuous phase structure. At pH 2.00 and 3.00, phase separation was suppressed, resulting in a homogeneous microstructure. Compared to the phase-separated gels at pH 4.00–11.00, the homogeneous systems at pH 2.00 and 3.00 displayed a synergistic effect with higher gel strength. Analysis of intermolecular forces in the GE/HPS gel indicated that hydrogen bonding was the primary interaction force. Furthermore, the addition of GE/HPS into hawthorn jelly at about pH 3.00 effectively preserved the structural appearance and exhibited higher levels of hardness, thus improving the sensory properties of hawthorn jelly. In summary, phase separation decreased the storage modulus of GE/HPS gel, but the compatibility of GE/HPS macromolecules exhibited synergistic effects at 2.00 and 3.00 and improved the hydrogel mechanical properties. This work provides some new insights for GE/HPS-based gel foods.
研究领域:
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Wenxing Zhu,Jianhua Pan,Xinyang Yu,Guichun He,Cheng Liu,Siyuan Yang,Yuhui Zeng,An Zeng,Taotao Liu
The effect of hydroxypropyl starch (HPS) on the flotation separation of fluorite from calcite using sodium oleate (NaOl) as a collector was studied. Micro-flotation results of single minerals showed that both fluorite and calcite presented good floatability in the presence of NaOl. However, by adding HPS before NaOl, the calcite flotation recovery was selectively reduced. The flotation of artificially mixed minerals confirmed that an efficient separation of fluorite from calcite could be achieved using the reagents scheme of HPS/NaOl. Zeta potential measurements demonstrated that HPS prevented the NaOl adsorption onto the calcite surface while it did not inhibit the interaction of NaOl with the fluorite surface. Fourier Transform Infrared (FT-IR) analysis was also revealed that the selective adsorption of HPS onto the calcite surface.
研究领域:
矿物加工工程
·
表面化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
·
2013
·
IF 2.487
Qiang Wu,Dong-Qiang Lin,Shan-Jing Yao
The aqueous two-phase system (ATPS) with polyethylene glycol (PEG) and hydroxypropyl starch (HPS) was evaluated for the extraction of human immunoglobulin G (IgG) from human serum albumin (HSA). The partitions of IgG in PEG/sulphate, PEG/phosphate, PEG/Dextran and PEG/HPS ATPSs were compared, and the results indicated that PEG/HPS system was most suitable for IgG extraction. The effects of the concentrations of PEG, HPS and NaCl addition and pH on the partition of IgG and HSA in PEG/HPS ATPS were investigated. It was found that with 15% NaCl addition at pH 8.0 IgG could be largely recovered in the top PEG-rich phase and most of HSA kept in the bottom phase. In addition, the response surface methodology (RSM) was used to optimize the extraction of IgG from the protein mixture of IgG and HSA. The optimal conditions were obtained as 12% (w/w) PEG 4000, 18% (w/w) HPS and 10% (w/w) NaCl at pH 8.0. The extraction yield of IgG in the top phase was 99.2% and the purification factor could reach 5.28. The back extractions of IgG into a phosphate-rich bottom phase were also studied. The total purification factor was 5.73 with the yield of 84.0%. The results indicated that PEG/HPS ATPS might be a promising alternative for the primary recovery of IgG from the complicated feedstock.
研究领域:
生物化学
·
蛋白质工程
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2017
·
IF 3.671
Siyuan Liu,Xiaoxi Li,Ling Chen,Lin Li,Bing Li,Jie Zhu
From the view of multi-scale structures of hydroxypropyl starch (HPS)/carbon nanotube (CNT) nanocomposite films, the film physicochemical properties were affected by comprehensive factors including molecular interaction , short range molecular conformation, crystalline structure and aggregated structure. The less original HPS hydrogen bonding that was broken, less decreased order of HPS short range molecular conformation, lower film crystallinity and larger size of micro-ordered regions contributed to higher tensile strength and Young’s modulus of the film with CNT content of 0.5% (g/g, CNT in HPS). The higher film overall crystallinity and larger size of micro-ordered regions of the film with CNT content of 0.05%–0.3% compared with those of control contributed to better film barrier property. The addition of CNT with the content of 0.05%–0.5% broke the original HPS hydrogen bonding and decreased the order of starch short range molecular conformation, which counteracted the positive effect of CNT on the thermal stability of the material, thus thermal degradation temperature of these nanocomposite films did not increase. But the sharp increase of film crystallinity increased film thermal degradation temperature. This study provided a better understanding of film physicochemical properties changes which guides to rational design of starch-based nanocomposite films for packaging and coating application.
研究领域:
材料科学
·
食品科学
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Arabian Journal of Chemistry
·
2022
·
IF 6.212
Zhenzhong Zang,Shichun Zhao,Ming Yang,Chengqun Yu,Hui Ouyang,Lihua Chen,Weifeng Zhu,Zheng-gen Liao,Abid Naeem,Yongmei Guan
Honeysuckle is a commonly used Chinese medicine for treating intestinal inflammation and other diseases. Compounds that are absorbed into the blood produce pharmacodynamic effects. However, it is still unclear which compounds in honeysuckle are absorbed into the blood. Thus, the purpose of this study was to investigate the composition and in vivo absorption of active components in honeysuckle in male Sprague-Dawley rats, and develop a controlled release hydrogel system. UPLC-LTQ-Orbitrap-MS was used to determine the active ingredients of honeysuckle in vitro and in vivo . A total of 80, out of which 42 components were found to be absorbed into the blood, which includes flavonoids, iridoids, organic acids and other compounds. FTIR analysis confirmed crosslinking between hydrogel content and drug loading, and TGA and DSC analysis indicated a high thermal stability. XRD analysis showed a decrease in crystallinity following crosslinking, and SEM revealed an irregular and hard surface. The maximum swelling and drug release were observed at pH 7.4 as compared to pH 1.2. The identified blood components can be used to determine Q-markers, while the prepared hydrogels can serve as an effective and promising carrier for the controlled release of honeysuckle extracts.
研究领域:
中药学
·
药剂学
·
分析化学
✓ 已验证
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2016
·
IF 4.219
Siyuan Liu,Panfu Cai,Xiaoxi Li,Ling Chen,Lin Li,Bing Li
To improve the water vapor resistance of starch-based films, Na-MMT (Na-montmorillonite) as nanofillers were fabricated into hydroxypropyl starch and the multi-scale structural changes (including intermolecular interaction, short-range conformation, long-range ordered structure and the aggregated structure of the film) were revealed. The elongation of the water vapor molecule pathway by tortuous path is generally recognized as the main reason for the improvement of water resistance. However this study observed the lowest water vapor permeability (WVP) was at the 3% Na-MMT/hydroxypropyl starch (HPS) ratio instead of 5% even nanofillers were partially exfoliated at both ratio. Except for the “tortuous path” caused by nanofillers, this observation proposed that the short-range conformation of HPS chains, long-range ordered structure and the aggregated structure likely influenced the water barrier property. The relationship between WVP and multi-scale structure of the film was investigated. The results suggested that a good balance of short-range conformationin the amorphous region, long-range ordered structure and the aggregated structure of the film was required for the improvement of water vapor barrier property.
研究领域:
材料科学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Yanfei Wang,Jing Wang,Qingjie Sun,Xingfeng Xu,Man Li,Fengwei Xie
This work investigates the structure, processability, and film performance of hydroxypropyl methylcellulose (HPMC) hydrocolloids affected by hydroxypropy substitution degree and blending with hydroxypropyl starch (HPS). The hydroxypropylation of HPMC could increase inter-chain hydrogen bonding, thereby promoting its gelation, and improve film-forming, but reduce the mechanical properties of the films. HPMC-HPS mixed hydrocolloid system showed a typical “sea-island” morphology with the continuous phase changing with blend ratio. The content of hydroxypropy groups of HPMC affected the compatibility between HPMC and HPS, the morphology of the discrete phase, and the rheological properties of the blends. The fluid-like HPS enhanced the gel strength of HPMC when they had better compatibility. With a higher degree of hydroxypropy substitution, blend films exhibited a much denser structure, better oxygen barrier property, and appropriate mechanical properties. The knowledge obtained from this work could guide the development of edible packaging materials with desired properties and functionality.
研究领域:
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2023
·
IF 8.8
Yihui Wang,Yueyue Yang,Liangyun Xu,Chao Qiu,Aiquan Jiao,Zhengyu Jin
There is an increasing demand for stable, highly viscoelastic, and printable emulsion gels based on pea protein (PeaP) as a substitute for animal fat. In this article, a simple pH modulation strategy was applied to regulate high internal phase (HIPE) gels prepared from PeaP and hydroxypropyl starch (HPS). The results showed that the interfacial tension of PeaP decreased from 11.9 to 7.1 mN/m at 5% PeaP and from 9.9 to 6.3 mN/m at 10% PeaP with increasing pH from 7 to 11. The incorporation of HPS improved the strength and physical stability of the HIPE gel. HIPE gels showed the best three-dimensional printing ability at pH 11. The main mechanism of HIPE gels at pH 3 was hydrophobic interaction, while electrostatic interaction dominated at pH 7, 9, and 11. This study may provide insights into the development of PeaP-based HIPE gels as a printable fat alternative.
研究领域:
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Yinjuan Cao,Zhaoyang Song,Wenjing Ni,Yabin Ma,Keqi Xin,Qunli Yu,Li Zhang
In the present study, the structure of potato oxidized hydroxypropyl starch (OHS) was analyzed. Carrageenan (CA) was used as a reinforcing agent for the development of biodegradable food packaging materials . Broccoli leaf polyphenol/soybean protein isolate/hydroxypropyl methylcellulose composite nanoparticles (SPH NPs) were used to reinforce OHS/CA (OC) films, and their physicochemical, structural, antioxidant, antimicrobial, and biodegradable properties were characterized. The OHS had high transparency, low gelatinization temperature (GT), and easy film formation. Intermolecular hydrogen bonds were formed between the SPH NPs and the OC film matrix, but did not change the crystal structure of the matrix. Furthermore, the incorporation of SPH NPs improved the smoothness, densification, and thermal stability of the OC films. Since SPH NPs occupied the pores of the film matrix, the degree of swelling, light, and moisture-blocking properties were improved, causing the films to gradually turn red, yellow and dark. Notably, the tensile strength of the film was significantly increased from 11.06 MPa to 13.61 MPa at a concentration of 3% SPH NPs. The SPH NP 3 -loaded films showed scavenging activity up to 67.62% and 75.45% against DPPH and ABTS free radicals , with good inhibitory activity against S. aureus and E. coli . More importantly, the composite film was almost completely degraded after 45 d of burial in the soil, and it can regulate the soil microbial community . Consequently, OHS composites can be used as a potentially versatile and environmentally friendly film-forming material for food packaging.
研究领域:
食品科学
·
材料科学
·
生物技术
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2017
·
IF 3.671
Huigao Wen,Jin Hu,Hongyu Ge,Shengqiong Zou,Yao Xiao,Ya Li,Han Feng,Lihong Fan
The preparation of aminoethyl hydroxypropyl starch collagen peptide (AEHPS-COP) was via an enzyme-catalyzed reaction between amino groups in aminoethyl hydroxypropyl starch (AEHPS) and γ-carboxamide groups in collagen peptide (COP) by using microbial transglutaminase (MTGase) as biocatalyst . As an intermediate reactant, AEHPS was synthesized from hydroxypropyl starch (HPS) and 2-chloroethylamine hydrochloride (CEH). The chemical structures of HPS, AEHPS and AEHPS-COP were characterized by Fourier transform infrared spectroscopy (FT-IR) and 13 C nuclear magnetic resonance ( 13 C NMR). The reaction conditions that influenced the degree of substitution (DS) of AEHPS-COP were optimized, which included the reaction temperature, the reaction time, the mass ratio of collagen peptide to aminoethyl hydroxypropyl starch and the pH value. In addition, in vitro antioxidant activities of AEHPS-COP were evaluated through the scavenging activity of hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. Furthermore, the methylthiazol tetrazolium (MTT) assay was applied to investigate the cell viability of AEHPS-COP. The results indicated that the AEHPS-COP exhibited better cell viability to L929 mouse fibroblast cells. Therefore, the AEHPS-COP showed a promising potential application in cosmetic, biomedical and pharmaceutical fields.
研究领域:
生物化学
·
材料科学
·
医药学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）