CARBOHYDRATE POLYMERS
·
2014
·
IF 3.916
Dengshan Bao,Mingjie Chen,Haiying Wang,Jufang Wang,Chuanfu Liu,Runcang Sun
A novel crosslinked hydrogel film was prepared from carboxymethylchitosan (CMCS) and carboxymethylcellulose (CMC) by ionical and covalent crosslinking with CaSO 4 and genipin, respectively. The swelling ratio of the crosslinked CMCS/CMC hydrogel films was investigated at different pH solutions (1–9), and the results indicated that the crosslinked hydrogels had the swelling–deswelling properties with two primary peaks of swelling ratio at pH 3 and 7. The surface morphologies of the crosslinked hydrogels at different pH values provided evidences of the swelling–deswelling properties. The mechanical properties of the hydrogel films were also examined. The ionical and covalent crosslinking were found to have the primary impact on the toughness and max load, respectively, of the crosslinked hydrogels. The cells comparatively cultured on the crosslinked hydrogels and the negative and positive controls suggested the biocompatibility of the crosslinked CMCS/CMC films. This kind of hydrogel films have potential application in drug delivery vehicles and skin tissue engineering.
研究领域:
材料科学
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生物医学工程
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DOI
PubMed
高影响因子
Bioresources and Bioprocessing
·
2024
·Vol. 11
·期 1
·1-14
·
IF 4.3
Chen Ming,She Weina,Zhao Xin,Chen Cheng,Zhu Benwei,Sun Yun,Yao Zhong
The Thermomyces lanuginosus lipase (TLLs) was successfully immobilized within a novel hydrogel matrix through a two-step crosslinking method. TLLs were initially crosslinked through the Schiff base reaction by oxidized carboxymethyl cellulose (OCMC). The water-soluble OCMC@TLLs complex was subsequently crosslinked by carboxymethyl chitosan (CMCSH) in a microfluidic apparatus to form the CMCHS/OCMC@TLLs microspheres. The CD (Circular Dichroism, CD) and FT-IR (Fourier Transform infrared spectroscopy, FT-IR) spectra demonstrated that the crosslinking of TLLs with OCMC resulted in a less significant impact on their structure compared to that with glutaraldehyde. CMCHS/OCMC@TLLs showed decreased catalytic performance due to the mass transfer resistance, while its thermal stability was greatly improved. The CMCHS/OCMC@TLLs were used to catalyze the lauroylation of arbutin in tetrahydrofuran. After 12 h of reaction under optimal conditions, the yield of 6′-O-lauryl arbutin reached an impressive 92.12%. The prepared 6′-O-lauryl arbutin has high lipophilicity and exhibits similar tyrosinase inhibitory activity and higher antioxidant activity compared to its parent compound.
研究领域:
生物化学
·
酶工程
·
食品科学
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DOI
PubMed
高影响因子
MOLECULES
·
2019
·Vol. 24
·期 15
·2704
·
IF 3.06
Chao Liu,Youming Li,Yi Hou
Carboxymethyl lignin nanospheres (CLNPs) were synthesized by a two-step method using microwave irradiation and antisolvent. The morphology and structure of CLNPs were characterized by31P-NMR, FTIR, and SEM, and the results showed that they had an average diameter of 73.9 nm, a surface area of 8.63 m2or 3.2 times larger than the original lignin, and abundant carboxyl functional groups of 1.8 mmol/g. The influence of dosage, pH, contact time, and concentration on the adsorption of metal ions onto CLNPs were analyzed, and the maximum adsorption capacity of CLNPs for Pb(II) was found to be 333.26 mg/g, which is significantly higher than other lignin-based adsorbents and conventional adsorbents. Adsorption kinetics and isotherms indicated that the adsorption of lead ions in water onto CLNPs followed the pseudo-second-order model based on monolayer chemisorption mechanism. The main chemical interaction between CLNPs and lead ions was chelation. CLNPs also showed an excellent recycling performance, with only 27.0% adsorption capacity loss after 10 consecutive adsorption–desorption cycles.Keywords:lignin;carboxymethyl;nanosphere;adsorption;lead
研究领域:
环境科学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2013
·
IF 3.777
Chong Sun,Xiaobo Wang,Xujie Yang,Lei Xing,Bo Zhao,Xiaodi Yang,Chun Mao
In this paper, we reported a novel label-free electrochemical aptasensors for thrombin detection in whole blood using self-assembled multilayers with carboxymethyl-PEG-carboxymethyl (CM-PEG-CM) and thrombin-binding aptamer (TBA). In the sensing strategy, CM-PEG-CM and TBA were assembled on the electrode surface via covalent binding. In the presence of target, the TBA on the outermost layer of the self-assembled multilayer would catch the target on the electrode interface, which makes a barrier for electrons and inhibits the electro-transfer, resulting in the decreased DPV signals. Using this strategy, a wide detection range (1 pM–160 nM) for target thrombin was obtained, with a low detection limit of 1.56 × 10 −14 M. The control experiments were also carried out by using bull serum albumin (BSA) and lysozyme in the absence of thrombin. The results showed that the aptasensors had good specificity, stability and reproducibility to thrombin. Moreover, the aptasensors could be used for detection of thrombin in whole blood which could provide a promising platform for fabrication of aptamer based biosensors in clinical application.
研究领域:
生物医学工程
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分析化学
·
分子诊断
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Zechao Huangfu,Wei Sun,Runqing Liu,Chen Chen,Chenyang Zhang,Heng Yu,Siyuan Liu
The effective recovery of talc-bearing molybdenum ores has been a research hotspot in the field of minerals processing, which is mainly attributed to the similarity of the physical and chemical properties of talc and molybdenite, especially floatability, which presents a challenge in the separation of the two during the beneficiation process. Herein, the coordination affinity, differentiated adsorption configurations, adsorption morphology, and bonding mechanisms of a polysaccharide-based depressant, carboxymethyl starch (CMS), on the layered hydrophobic minerals molybdenite and talc have been compared and its special use in flotation was investigated by various advanced techniques, including density functional theory (DFT) simulation, time-of-flight secondary ion mass spectrometry (TOF-SIMS) and X-ray photoelectron spectroscopy (XPS). The CMS adsorption on the talc surface was more affinitive than that of molybdenite and it is possible to achieve the selective separation of laminar hydrophobic minerals molybdenite and talc through the utilization of differential wettability. Flotation kinetics with 400 mg/L CMS as a depressant and 3*10 −3 mol/L sodium diethyldithiocarbamate (DDTC) as a collector has highlighted the importance of the mineral particle sizes that the better depressant activity of CMS on the coarse-grained talc surface in comparison to that of molybdenite is attributed to the greater adsorption energy and more homogeneous adsorption morphology of CMS on the talc basal surface which is the dominant surface affecting the floatability.
研究领域:
矿物加工工程
·
材料科学与工程
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产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2010
·
IF 5.214
Linyan Yang,Li Li,Qin Tu,Li Ren,Yanrong Zhang,Xueqin Wang,Zhiyun Zhang,Wenming Liu,Liangliang Xin,Jinyi Wang
An improved approach for the surface modification of poly(dimethylsiloxane) (PDMS) using carboxymethyl cellulose (CMC), carboxymethyl β-1,3-dextran (CMD), and alginic acid (AA) was investigated. The PDMS substrates were first oxidized in a H2SO4/H2O2 solution to transform the Si−CH3 groups on their surfaces into Si−OH groups. Then methacrylate groups were grafted onto the substrates through a silanization reaction using 3-(trimethoxysilyl)propyl methacrylate. Sequentially, cysteamine was conjugated onto the silanized surfaces by the reaction between the thiol and methacrylate groups under 254 nm UV exposure. Afterward, the amino-terminated PDMS substrates were sequentially reacted with CMC, CMD, and AA in the presence of N-hydroxysuccinimide and 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide, resulting in the grafting of polysaccharides onto PDMS surfaces. The composition and chemical state of the modified surfaces were characterized by X-ray photoelectron spectroscopy (XPS). In addition, the stability and dynamic characteristics of the polysaccharide-grafted PDMS substrates were investigated by XPS and temporal contact angle experiments. A protein adsorption assay using bovine serum albumin (BSA), chicken egg albumin, lysozyme, and RNase-A showed that the introduction of CMD and AA can reduce the adsorption of negatively charged BSA and chicken egg albumin, but increase the adsorption of the positively charged lysozyme and RNase-A. However, CMC-modified PDMS surfaces showed protein-repelling properties, regardless of whether the protein was positively or negatively charged. A cell culture and migration study of glioma C6, MKN-45, MCF-7, and HepG-2 cells revealed that the polysaccharide-modified PDMS greatly improved the cytocompatibility of native PDMS.
研究领域:
材料科学
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生物材料
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Heng Yu,Wei Sun,Chenyang Zhang,Zechao Huangfu,Fuchao Fan
Due to the limitations of existing flotation technologies, the resource development of talc-containing molybdenum ores remains an urgent issue that must be addressed. The development of effective talc depressants has become a significant research focus. Studies indicate that the combination of sodium carboxymethyl starch (CMS) and magnesium ion (Mg 2+ ) can effectively inhibit talc, achieving high selective flotation of molybdenite. However, the interaction mechanism between CMS and Mg 2+ , as well as its depressing mechanism on the anisotropic surface of talc, remains unclear. To address this issue, this study employed multiple testing methods and combined micro-flotation tests to systematically compare the differences in adsorption and bonding mechanisms between the mixed dosing system and the sequential dosing system on various crystal surfaces of talc and molybdenite, while also exploring their impact on flotation behavior. The research results indicate that in the mixed dosing system, CMS and Mg 2+ interact with the surface of talc through complex formation, which enhances its hydrophilicity. When the concentration of CMS is 1 × 10 -3 mol/L, the average recovery rate of talc decreases to 14.82 %, while the recovery rate of molybdenite reaches 84.85 %, thereby facilitating the selective separation of talc and molybdenite.
研究领域:
矿物加工工程
·
表面化学
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产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2018
·
IF 5.158
Jun Ye,Mingming Zhang,Jian Xiong
A novel, rapid, high selective and sensitive probe, carboxymethyl cellulose (CMC)/Tb(III) with green fluorescence, for detecting Mn 2+ in aqueous solution during pH = 4–10 was proposed in this work. The probe’s synthesis had benefits of mild reaction condition, organic solvent-free and facile operation. A linear relationship between the fluorescence intensity of CMC/Tb(III) probe at 544 nm with 0.046 μM detection limitation and the concentration of Mn 2+ in the range of 0.1–100 μM was obtained. The probe was also used to detected Mn 2+ in tap water and the recoveries were between 97.10% and 101.61%, and the relative standard deviations (RSD, n = 5) of all samples were less than 2.04%. The results by UV absorption spectrum and fluorescence quenching suggested that there might be a dynamic quenching occurred to the fluorescence of CMC/Tb(III) probe when Mn 2+ was involved.
研究领域:
分析化学
·
环境科学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2014
·
IF 4.058
Jing Wang,Xiaoyan Lin,Xuegang Luo,Yufeng Long
A novel sorbent for the removal of fluoride is prepared by immobilizing Zr(IV) on carboxymethyl cellulose sodium (CMC-Zr). Batch adsorption experiments are performed on factors of pH, temperature, initial fluoride concentration, adsorbent dosage and contact time to evaluate the adsorption capacity. The results show that the saturation adsorption capacity is 47 mg/g at pH 4.0, 25 °C, concentration 300 mg/L for 24 h. Adsorption process could be well described by Langmuir isotherm model. The adsorption kinetic data is fitted well with pseudo-second-order model. Thermodynamic parameters are also evaluated and the results indicate that adsorption of fluoride on CMC-Zr is a spontaneous and endothermic process. The mechanism of modification and adsorption process on CMC-Zr is analyzed by FT-IR, SEM-EDX and XPS. Results show that Zr(IV) is loaded on CMC through ion exchange of sodium of CMC and surface adsorption, coordination reaction happened during the adsorption process between CMC-Zr and fluoride. CMC-Zr adsorbent is a promising adsorbent for the removal of fluoride from aqueous solutions.
研究领域:
环境科学
·
化学工程
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产品关联
DOI
高影响因子
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
·
2018
·Vol. 99
·期 2
·e21499
·
IF 1.316
Lin Zhu,De-Qing Zou,Zuo-Qing Fan,Na Wang,Ying-Ying Bo,Yu-Qing Zhang,Guang Guo
In this study, a carboxymethyl chitosan derived from silkworm pupa (SP-carboxymethyl chitosan) was prepared. The physical characteristics of the SP chitin, chitosan, and carboxymethyl chitosan were analyzed. The scanning electron microscopy results showed that the surfaces of the samples from SP were more uneven, with more surface fractures compared with those of the reference substance (RS). Thermal analysis, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy analysis showed that the main molecular chain structures of SP samples and RSs had no substantial differences. However, the crystallinity and thermal decomposition temperature of the SP samples were lower compared with those of the RSs. All of these results provide a theoretical basis for the development of applications for the SP-carboxymethyl chitosan.
研究领域:
生物材料学
·
化学工程
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产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Shengkai Liu,Huiling Li,Xi Li,Wei Wang,Chunguang Rong,Mengjie Yang,Yonggui Wang,Jing Wang,Yabei Xu,Daxin Liang,Yanjun Xie
The titanium-based lithium ion sieve (HTO), renowned for its exceptional adsorption performance and cyclic stability, was utilized in addressing the global shortage of lithium resources. However, the recovery and reuse efficiency of HTO in powder form is relatively low, which limits its application in industrial fields. To address this issue, this study utilized carboxymethyl cellulose (CMC) as the principal matrix material, while polyvinyl alcohol (PVA) played a dual function as both matrix and crosslinker, negating the necessity for supplementary crosslinking materials. Employing water as the only solvent, HTO was embedded into the CMC-PVA blended film matrix. It was observed that augmenting the CMC content substantially elevates the adsorptive capability of the film. However, this enhancement comes at the cost of reduced mechanical robustness and diminished stability in solution. Consequently, by balancing the influence of adsorptive capacity and stability through fine-tuning the CMC-to-PVA ratio. Even when HTO powder is encapsulated within the film, the adsorption film retains the excellent adsorption properties of HTO, achieving an adsorption capacity for lithium of 29.21 mg g −1 within 12 h. This study provides an innovative pathway and ideas for the large-scale, low-cost production of sustainable lithium-ion adsorption materials.
研究领域:
材料科学
·
环境科学
·
化学工程
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产品关联
DOI
PubMed
高影响因子
Materials
·
2019
·Vol. 12
·期 6
·942
·
IF 2.972
Huo-Xi Jin,Hong Ping Xu,Nan Wang,Li-Ye Yang,Yang-Guang Wang,Di Yu,Xiao-Kun Ouyang
The ability to remove toxic heavy metals, such as Pb(II), from the environment is an important objective from both human-health and ecological perspectives. Herein, we describe the fabrication of a novel carboxymethylcellulose-coated metal organic material (MOF-5–CMC) adsorbent that removed lead ions from aqueous solutions. The adsorption material was characterized by Fourier-transform infrared spectroscopy, X-ray diffractometry, scanning electron microscopy, and X-ray photoelectron spectroscopy. We studied the functions of the contact time, pH, the original concentration of the Pb(II) solution, and adsorption temperature on adsorption capacity. MOF-5–CMC beads exhibit good adsorption performance; the maximum adsorption capacity obtained from the Langmuir isotherm-model is 322.58 mg/g, and the adsorption equilibrium was reached in 120 min at a concentration of 300 mg/L. The adsorption kinetics is well described by pseudo-second-order kinetics, and the adsorption equilibrium data are well fitted to the Langmuir isotherm model (R2= 0.988). Thermodynamics experiments indicate that the adsorption process is both spontaneous and endothermic. In addition, the adsorbent is reusable. We conclude that MOF-5–CMC is a good adsorbent that can be used to remove Pb(II) from aqueous solutions.Keywords:carboxymethylcellulose;adsorption;Pb(II);MOF-5
研究领域:
环境科学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）