Boshi Feng,Juanli Shen,Jinlong Zhang,Junli Ren,Xiaohong Liu,Shiyu Fu
Hydrogels have gained prominence as a distinctive material for smart healthcare devices and wearable electronics, owing to their inherent biocompatibility, tissue-like mechanical properties and superior water and oxygen permeability. In most application scenarios, hydrogels are required to have certain adhesion properties. However, current hydrogel adhesive systems are fundamentally constrained by two intrinsic material restrictions: low mechanical strength, and compromised adhesion in humid environments (under conditions such as sweating and bleeding), which severely restrict their practical applications. Inspired by the covalent and physical synergistic adhesion strategy of mussels and the interfacial water-capturing mechanism of spiderwebs, we designed and fabricated an ultrathin poly (acrylic acid) (PAA)/N-hydroxysuccinimide (NHS)/cellulose nanocrystal (CNC) composite hydrogel (PNCGels) tape. This PNCGels tape adopts a dry crosslinking mode, which enables the carboxyl groups in the hydrogel rapidly form physical interactions such as hydrogen bonds with tissue surface within less than 5 s. Subsequently, the NHS ester groups grafted onto PAA couple covalently with primary amine groups in the tissue. Additionally, the CNC nanofillers enhance cohesive strength by reconstructing a dynamic hydrogen-bonding network to balance adhesion, which ensures stable adhesion even in the presence of sweat. The resultant PNCGels tape displayed remarkable wearability (thickness of only 250 μm), excellent adhesive properties (adhesion strength: 128 kPa), good mechanical performance (tensile strength: 1400 kPa). The integrated features of ultra-slimness, high toughness, and humidity-resistant adhesion provide a transformative platform for advanced applications, including smart wound dressings (hemostasis, on-demand removal) and motion sensing technologies.
Tao Liu,Zhenzhen Nong,Yong Li,Zhuohang Liu,Zhuoyue Fan,Huansheng Liu,Qi Liu,Jianyu Qiu,Qingwen Wang,Zhenzhen Liu
Acquiring high-quality and long-term electrophysiological signals remains a critical challenge in human health monitoring. However, traditional commercial gel or paste skin electrodes are extremely susceptible to sweat, body motion, or environmental interference, seriously limiting the high-fidelity of outputted signals. Herein, a completely physical crosslinked eutectogel is prepared at room temperature, which displays low modulus yet high toughness because of the multiple hydrogen bonding interactions of konjac glucomannan (KGM) with other components of the gel network. This eutectogel not only exhibits superior adhesion to normal skin but also shows enhanced adhesion under sweating conditions, enabling seamless and ultraconformal skin contact. Furthermore, the eutectogel possesses excellent environmental stability, biocompatibility, and low interfacial contact impedance. Based on these merits, this eutectogel is used as a skin electrode for real-time monitoring of electrophysiological signals with extraordinary immunity to motion artifacts, sweat disturbance, and environmental interference, thereby providing a robust solution for the acquisition of electrophysiological signals. Graphical A physically crosslinked ALK eutectogel with superior adhesion to normal/sweaty skin, excellent low impedance persistence, remarkable environmental stability, and ultra-conformability with skin is developed for use as skin electrodes for real-time monitoring of electrophysiological signals, which exhibits extraordinary immunity to motion artifacts, sweat disturbance, and environmental interference, thus providing a robust solution for the acquisition of electrophysiological signals.
危险品化学品经营许可证（带存储）