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ADVANCED FUNCTIONAL MATERIALS · 2023 ·Vol. 34 ·期 3 ·2307503 · IF 19

Fully-Printed Bionic Tactile E-Skin with Coupling Enhancement Effect to Recognize Object Assisted by Machine Learning

Zhe Yu,Yanghuan Mao,Zhixin Wu,Fenglong Li,Jinwei Cao,Ya-Nan Zheng,Xiaolong Zhong,Lebin Wang,Jin Zhu,Pingqi Gao,Wu Bin Ying,Gang Liu

In the pursuit of tactile sensation resembling human skin, the electronic skin (E-skin) has long been a subject of interest and inspires the exploration of various biomimetic structures. Nevertheless, the exceptional functionality of living organisms arises from the synergistic interplay of multiple internal factors, i.e. the coupling enhancement effect, which has received limited attention in existing studies. Here, a tactile E-skin featuring a multicoupled biomimetic structure that mimics three coupling elements found in the skin: Stratum spinosum, Meissner corpuscle, and Piezo2 protein, is proposed. By amalgamating their distinguishing characteristics, this bionic E-skin surpasses the performance of conventional counterparts such as sensitivity as high as 388.5 kPa −1 , hysteresis as low as 0.76%, and response times as short as 10 ms. Furthermore, its fabrication methodology of efficient 3D printing shows great advantages in terms of production cost and customization. Finally, the sensor is expanded to a 9 × 9 pixels array for a machine learning-assisted intellisense system to recognize the fruits as a human does, achieving an accuracy of 91.4%. All of these prove the promising potential of this multicoupled biomimetic structure in wearable electronics, human–machine interface, soft robotics, and artificial sensing.

研究领域: 生物医学工程 · 材料科学 · 人工智能
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IEEE SENSORS JOURNAL · 2024 · IF 4.3

A new Acetylcholine optical fiber biosensor based on gold film-GNRs Resonance Coupling Enhancement

Yumei Zhang,Liyun Ding,Shiyuan Wang,Xingdong Jiang,Fei Ma,Jue Zhao,Wenbo Meng,Long Gao

An enhanced resonance coupling of gold film-gold nanorods (GNRs) based optical fiber acetylcholine (Ach) biosensor was fabricated with increased sensitivity for refractive index (RI) sensing. Gold film with a thickness of about 50 nm is sputtered on the surface of the optical fiber by the magnetron sputtering, and then the GNRs synthesized by seed-mediated were immobilized on the surface of the gold film by using 1,6-hexodithiol as a crosslinker via cross-link method. The RI sensitivities (SRI) improvement rate of the sensors was 24.09% higher than that of the sensor without GNRs functionalization. Acetylcholinesterase (AchE), as the specific recognition substance of the biosensor, was immobilized on the surface of GNRs by the chemical crosslinking method to prepare optical fiber sensing probes. Under the optimum preparation conditions of the optical fiber sensing probe, the wavelength shift of the surface Plasmon resonance (SPR) peak has a good linear relationship with the concentration of Ach (CAch) in the range of 0.5– $5 \mu \text{g}$ /mL with the sensitivity of 0.4912 nm/( $\mu \text{g}$ /mL) and limit of detection (LOD) was $0.45 \mu \text{g}$ /mL. In addition, the optical fiber biosensor has good stability and selectivity, which makes it have broad application prospects in the early diagnosis of degenerative disease.

CAS / MDL: 25952-53-8 6066-82-6
研究领域: 生物医学工程 · 传感技术 · 分子诊断
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Nano-Micro Letters · 2022 ·Vol. 14 ·期 1 ·1-14 · IF 23.655

Coupling Enhancement of a Flexible BiFeO3 Film-Based Nanogenerator for Simultaneously Scavenging Light and Vibration Energies

Han Xiao,Ji Yun,Wu Li,Xia Yanlong,Bowen Chris R.,Yang Ya

Coupled nanogenerators have been a research hotspot due to their ability to harvest a variety of forms of energy such as light, mechanical and thermal energy and achieve a stable direct current output. Ferroelectric films are frequently investigated for photovoltaic applications due to their unique photovoltaic properties and bandgap-independent photovoltage, while the flexoelectric effect is an electromechanical property commonly found in solid dielectrics. Here, we effectively construct a new form of coupled nanogenerator based on a flexible BiFeO 3 ferroelectric film that combines both flexoelectric and photovoltaic effects to successfully harvest both light and vibration energies. This device converts an alternating current into a direct current and achieves a 6.2% charge enhancement and a 19.3% energy enhancement to achieve a multi-dimensional "1 + 1 > 2" coupling enhancement in terms of current, charge and energy. This work proposes a new approach to the coupling of multiple energy harvesting mechanisms in ferroelectric nanogenerators and provides a new strategy to enhance the transduction efficiency of flexible functional devices.

CAS / MDL: 10035-06-0 10277-43-7
研究领域: 纳米技术 · 材料科学 · 能量收集 · 机电系统
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BIOCHEMICAL ENGINEERING JOURNAL · 2022 · IF 4.446

A membrane-type mechanical biosensor based on magnetic, surface stress and electric coupling enhancement for HSA detection

Pengli Xiao,Shengbo Sang,Qiang Zhang,Yang Ge,Yongqiang Cheng,Dong Zhao

Currently, mechanical biosensors were greatly applied in detecting various biomarkers. However, the sensitivity of the mechanical biosensor needs to be further improved to be expected to achieve higher performance for the single molecule detection. Herein, we proposed a membrane-type biosensor based on magnetic, surface stress and electric coupling enhancement (MSEC-MBios) to detect the human serum albumin (HSA). By introducing the magnetic probes, the membrane deformation was amplified under the magnetic field, realizing the coupling of the magnetic and the traditional electromechanical mechanical biosensor system. By magnetic sensitization, the detection limit of the MSEC-MBios was reduced to 10.2 ng/mL in the linear range of 0–50 μg/mL, which was an order of magnitude lower than that of the biosensor without magnetic field. In addition, the MSEC-MBios was also proved excellent stability, selectivity, and specificity, showing potential in developing new biomolecules detection methods.

CAS / MDL: 25952-53-8 6066-82-6
研究领域: 生物医学工程 · 生物传感器 · 纳米技术 · 分析化学
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Advanced Optical Materials · 2024 · IF 8

Strong-Coupling-Enhanced Raman Spectroscopy (SCERS) in a Cascade Microsphere-Cavity

Yanlin Mi,Zhiyang Xu,Chen Zhao,Tianrui Zhai,Yan Zhao,Yijian Jiang,Yinzhou Yan

Surface-enhanced Raman spectroscopy (SERS) is a powerful optical technique with high sensitivity to identify analytes down to a single molecule by fingerprinting vibrational information. The strong coupling in microcavities for supermodes with promoted quality factors demonstrates the capability to boost the interaction between photons and molecules for nonlinear effects. Here a strong-coupling cascade microsphere-cavity (MC) achieving spontaneous Raman enhancement is reported, for the first time. The cascade MC is composed of two size-mismatched microspheres, both of which support optical whispering-gallery modes (WGMs) with significantly different free-space ranges. The strong coupling between the supported WGMs in the microspheres can be achieved when the quasi-vernier effect of resonant modes occurs, by which the energy splitting is up to 4 meV. The fast energy transfer between the size-mismatched MCs therefore increases the quality factor up to 2.1 × 10 3 for the upper supermode branch. The strong-coupling cascade MC structure provides an extra enhancement channel for the Au-based SERS substrate, demonstrating an enhancement factor of Raman intensity ( EFRI ) up to 2.6 × 10 10 for the limit of detection ( LoD ) down to 10 −12 M of 4-aminothiophenol (4-ATP). The strong-coupling cascade MC substrates also exhibit the versatility for identification of multiple analytes for high-performance Raman trace-detection applications.

研究领域: 光学 · 分析化学 · 光子学 · 纳米技术
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Optical Materials Express · 2021 ·Vol. 11 ·期 7 ·2076-2088 · IF 3.442

Raman enhancement properties of Ag nano-islands with SiO2 microsphere arrays prepared by self-assembly technology and the thin-film annealing method

Chen Junfan,Chen Hongxian,Zhang Jie,Zhu Yong

Combining self-assembly technology and the thin-film annealing method, annealed Ag nano-islands (Ag NIs) with SiO2 microsphere (MS) arrays were prepared as surface-enhanced Raman scattering (SERS) substrate in this paper. A “top-binding” model was established to analyze the effect of SiO2 MS at different annealing temperatures and different Ag film thickness. The corresponding comparative analysis with and without MS templates have been carried on. We simulated the electric field enhancement, coupling enhancement spectrum and the optical focus function of SiO2 MS. Characterization and experiments showed that the use of a SiO2 MS array as a dewetting template can well regulate the size and morphology of Ag NIs. Among them, SiO2 MS-Ag-20 can achieve the most uniform particle size at an annealing temperature of 873.15 K. According to the UV-Vis absorption spectrum, it had an active SERS analytical enhancement factor (AEF) of ∼3.91×105 and good SERS reproducibility (relative standard deviation, RSD = 0.113) for R6G when the wavelength was 532 nm.

CAS / MDL: 989-38-8
研究领域: 材料科学 · 纳米技术 · 光学 · 分析化学
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