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BIOMACROMOLECULES · 2021 · IF 6.988

Controllable Synthesis of Polyphenol Spheres via Amine-Catalyzed Polymerization-Induced Self-Assembly

Zhiqing Liu,Wei Yu,Wenbo Sheng,Rui Li,Helin Guo,Xiantao Feng,Qian Li,Rongjie Wang,Wei Li,Xin Jia

A facile and general strategy for preparing uniform and multifunctional polyphenol-based colloidal particles through amine-catalyzed polymerization-induced self-assembly is described. The size and interfacial adhesion of polyphenol spheres can be easily controlled over a wide range via adjusting the concentration of the cosolvent and monomer. Moreover, the polyphenol spheres showed excellent thermal and chemical stability and highly active properties and could efficiently deplete the reactive oxygen species (ROS), which are helpful for in vivo ROS regulation for inflammatory therapeutic. The accessible and versatile method provides a feasible way for the rational engineering of multifunctional polyphenol spheres, which have great potential in many fields.

研究领域: 材料科学 · 生物医学 · 化学工程
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