JOURNAL OF MEMBRANE SCIENCE
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2022
·
IF 10.53
Ke Bai,Senqing Fan,Yu Chen,Yilin Wang,Jiaojiao Chen,Zenghui Mai,Jingyun Liu,Lei Deng,Zeyi Xiao
A membrane adsorber with hierarchically porous HKUST-1 (HP-HKUST-1) immobilized in membrane pores has been fabricated by flowing synthesis. The X-ray diffraction (XRD) characteristics indicate that the structural integrity of the HP-HKUST-1 immobilized in the membrane pores can be kept after template agents are removed. Other characteristics prove the effective immobilization of HP-HKUST-1 in membrane pores. As a concept-of-proof, the adsorption for Congo red (CR) and Methylene blue (MB) is carried out to evaluate the adsorption performance of the membrane adsorber. The adsorption capacity for CR with 458 mg g -1 and MB with 241 mg g -1 can be obtained by HP-HKUST-1 powder, which is 2–3 times higher than those by HKUST-1 powder, owing to the mesopores with rich active adsorption sites. When the solution flows through the membrane adsorber, the adsorption rate for these adsorbates in the range of 0.049 g mg -1 h -1 and 0.129 g mg -1 h -1 can be obtained, which is 4–5 times higher than that by HP-HKUST-1 powder, owing to the enhanced mass transfer in the confined space of the membrane pores with micro or nano scale. After going through seven adsorption-desorption experiments, the membrane adsorber with HP-HKUST-1 immobilized shows remarkable repeatability.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Qi Zhao,Xiaoyue Liang,Chunju He
Solid phase extraction is an effective method for the separation and purification of nucleic acid molecules, which still suffers from high loss and low efficiency. Herein, a polyether sulfone membrane adsorber for deoxyribonucleic acid (DNA) separation and purification is constructed by combining vapor-induced phase separation (VIPS) technique and in-situ coupling reaction. More specifically, the slow phase separation during VIPS promotes the formation of reaction platform with loose bicontinuous structure, high porosity and surface segregation of poly (acrylic acid), which is subsequently highly aminated by in-situ coupling of polyethyleneimine. Significantly, the reversible binding of amine ligands to DNA is solely based on electrostatic interaction, which is regulated by medium pH, avoiding the requirement for additional binding agents as encountered by commercial silica matrices and dramatically reducing DNA loss. Consequently, the resulting membrane adsorber exhibits excellent DNA binding capacity of 293.3 mg·g −1 and improved dynamic DNA recovery efficiency of 85.2 %, far exceeding that of commercial silica matrices (55.5 %). This work provides a major breakthrough in the field of nucleic acid separation and purification, paving the way to construct next-generation solid phase extraction materials for biomacromolecules.
研究领域:
生物技术
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分子生物学
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2018
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IF 3.716
Fan Hu,Zhanghui Wang,Baoku Zhu,Liping Zhu,Youyi Xu
Energy-efficient and time-saving process for recovery of hazardous dyes from wastewater is highly desired in dyeing industry. In this work, poly( N -vinyl imidazole) (PVI) gel-filled membrane adsorbers were developed for highly efficient recovery of dyes through adsorption filtration. The membrane adsorbers were fabricated via dip-coating of Nylon macroporous membranes in PVI solutions followed by quaternization crosslinking with p-xylylene dichloride (XDC). Physicochemical characterizations indicated that PVI gel was successfully filled and fixed inside the Nylon matrix. In optimized conditions. The treating capacity of membrane adsorbers to typical dye sunset yellow (25 ppm of the feed concentration) reached up to 197 mg/g with the removal ratio >99%. Both the treating capacity and the removal ratio were kept steady even when the permeation flux was as high as 1000 L/m 2 h. The membrane adsorbers developed in this work were able to not only remove anionic dyes from water, but also separate anionic dyes from cationic ones. The zeta potential and adsorption tests showed that the electrostatic interaction between PVI gel and dye molecules was responsible for the high removal efficiencies to anionic dyes. The membrane adsorbers can be regenerated effectively with NaOH solution and demonstrated good stability in both acidic and alkaline conditions.
研究领域:
环境科学
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材料科学
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化工工程
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Qian Wu,Jinxin Fan,Xiangrong Chen,Zhenzhou Zhu,Jianquan Luo,Yinhua Wan
Aflatoxins as toxic substances produced by microorganisms widely existed in food crops and detoxification of aflatoxins is highly desired to avoid their leaking into the environment. Herein, a novel combination strategy of metal organic frameworks (MOFs) and porous membrane was used to prepare membrane adsorbent for aflatoxin B1 (AFB1) removal. Firstly, the MOFs particles were readily fixed on a porous membrane by reverse filtration. Subsequently, polydopamine (PDA) coating and further charged polymer grafting were employed for sealing the MOFs particles. By systematically studying four kinds of MOFs particles for AFB1 adsorption, the MIL-100 and the resultant MIL-100 loaded membrane outperformed the other MOFs materials. Through comprehensively evaluating five different sealing approaches, it was found that the charge of the grafted polymers on the membrane was critical for AFB1 adsorption. The PDA/alginate dialdehyde (ADA) modified MIL-100 loaded membrane prepared with PDA coating and ADA grafting for 30 min, could achieve the highest AFB1 removal efficiency of 76.4% and the membrane stability was greatly improved, meanwhile the water permeate flux was barely affected by the additional layers. A good reusability could be realized by a facile desorption process and the AFB1 removal efficiency kept at 61.8% after five reuse cycles. When dealing with real corn juice, the AFB1 removal efficiency in flow-through mode was lower than that obtained in dipping incubation mode, because severer membrane fouling occurred during dynamic adsorption which blocked the adsorption sites on the membrane. The present work not only demonstrated a reliable and effective approach to synthesize robust MOFs-loaded membrane for AFB1 removal, but also offered new insights into micropollutant removal with MOFs derived materials.
研究领域:
食品科学
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环境科学
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材料科学
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DOI
高影响因子
MACROMOLECULAR MATERIALS AND ENGINEERING
·
2019
·Vol. 304
·期 6
·1800790
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IF 3.038
Lanfang Liu,Jianquan Luo,Yinhua Wan,Xiangrong Chen,Yuanpeng Wu
Mussel-inspired membrane adsorber with thiol ligand (SH-membrane adsorber) is prepared by polydopamine-assisted poly(ethylene imine) grafting and subsequent thiolation modification for efficient removal of patulin. The effects of temperature, contact time, pH, and initial patulin concentration on the adsorption capacity of the membrane adsorber are investigated. The results show that the SH-membrane adsorber is effective to remove patulin. The adsorption capacity of the membrane can reach 1245.11 µg g −1 for patulin. In static adsorption tests, the adsorption kinetic and equilibrium data are well fitted by the pseudo-second-order kinetic model and Freundlich isotherm model, respectively, meaning that the adsorption process is a multilayer chemical adsorption. The SH-membrane adsorber can be recovered by l -cysteine, and the removal efficiency of patulin is maintained at about 89.23% after eight reuse cycles, compared to the 17.33% of control membrane. These results demonstrate that the SH-membrane adsorber has a potential application for patulin removal.
研究领域:
食品科学
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环境工程
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生物化学
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DOI
高影响因子
Journal of Materials Chemistry B
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2018
·Vol. 6
·期 11
·1640-1649
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IF 4.776
M. Kamran Khan,Jianquan Luo,Zhaoshuai Wang,Rashid Khan,Xiangrong Chen,Yinhua Wan
Alginate dialdehyde (ADA), a biocompatible polymer, was used as an intermediate layer on a nylon membrane to readily fabricate cation exchange (CEX), metal-affinity (Me-affinity), histidine-affinity (His-affinity) and peptide-affinity (Pep-affinity) membrane adsorbers without any organic solvent usage. All the membrane adsorbers exhibited a high selectivity in the fractionation of a IgG (immunoglobulin)/HSA (human serum albumin) mixture. Along with a high purity of 100%, a high IgG binding capacity of 30, 24, 21 and 28 mg mL−1 (membrane volume) was achieved by the CEX, Me-affinity, His-affinity and Pep-affinity membrane adsorbers in flow-through mode respectively, which is superior to those of the reported membrane adsorbers. Furthermore, the CEX and Pep-affinity adsorbers were tested for the separation of IgG from human plasma solution. The carboxylic groups along with the peptides on the Pep-affinity adsorber captured IgG synergistically with a higher recovery and purity (99% and 98.6%). This synergetic adsorber showed a qmax and dynamic binding capacity (DBC) of 138.4 and 38.7 mg mL−1 respectively for IgG binding which was somewhat higher than that of the reported protein A agarose (having qmax and DBC of 84 and 24.4 mg g−1 respectively). The present work indicated that the ADA layer not only activated the membrane surface to attach various adsorptive ligands under mild conditions, but also reduced non-specific adsorption. Due to the versatile linking function and green reaction conditions, the ADA coating on the nylon membrane is promising for the preparation of diverse membrane adsorbers.
研究领域:
生物工程
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材料科学
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分离技术
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DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2024
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IF 8.4
Qi Zhao,Xiaoyue Liang,Xueyu Zhang,Chunju He
Ion exchange membrane adsorbers, an alternative to overcome the bottleneck of present deoxyribonucleic acid (DNA) solid-phase extraction material, still suffer from scarce binding capacity and uncontrollable recovery efficiency. Herein, inspired by mussel adhesion combined with in-situ coupling technique, a silane-modulated biomimetic amination strategy is proposed to construct an anion-exchange membrane adsorber for efficient DNA separation. The coupling of polyethyleneimine to the biomimetic interlayer formed by the co-coating of pyrogallol and 3-glycidoxypropyltrimethoxysilane onto polyethersulfone membranes provides high coverage of DNA-binding ligands for the resulting membrane adsorber. Furthermore, its surface charge properties are tailored by the tunable content of epoxy groups in the biomimetic interlayer, resulting in the pH-responsive reversible DNA binding capacity. Consequently, the resulting membrane adsorber exhibits unprecedented DNA adsorption capacity (396.2 mg g −1 ), which is renewable and requires no external binding agent. More importantly, this membrane adsorber in the form of spin columns achieves outstanding DNA recovery efficiency up to 88 %, which is 32 % improvement over commercial silica matrices. This research provides a new perspective on the design of novel ion exchange membrane adsorbers and holds promise for the low-loss, high-efficiency downstream separation and purification processes of biomacromolecules.
研究领域:
生物化学
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材料科学
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分子生物学
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DOI
高影响因子
RSC Advances
·
2018
·Vol. 8
·期 71
·41003-41011
·
IF 2.936
Wen Bing Wu,Sun Xue,Jian Hua Chen,Xiao Li
Membrane separation technologies have great promising potential for applications in several industries. Metal–organic frameworks (MOFs), for their large surface areas, low framework densities, transition-metal ions in the skeleton and high pore volumes relative to other porous matrices, have great potential for the removal of sulfur from gasoline with high efficiency. In the present study, a novel porous membrane adsorbent MIL-101(Cr)/SA was prepared by immobilizing MIL-101(Cr) onto sodium alginate (SA) matrix, which can combine the size/shape selectivity of MIL-101(Cr) with the processability and mechanical stability of SA polymer. The physico-chemical properties of MIL-101(Cr)/SA were investigated by FT-IR, SEM, BET, XRD and EDX methods. To investigate the effects of some important factors on the adsorption behavior for thiophene, a batch of experiments were performed by changing the concentration of porogen polyethylene glycol in the MIL-101(Cr)/SA, solution temperature, initial thiophene concentration and contact time. Meanwhile, benzothiophene, thiophene and 3-methyl thiophene were used to test the selectivity of MIL-101(Cr)/SA. The MIL-101(Cr)/SA showed an excellent uptake capacity of 671 mg g−1 under the optimal adsorption conditions. Selectivity testing indicated that the uptake capacity of MIL-101(Cr)/SA follows the order of benzothiophene > thiophene > 3-methyl thiophene. Kinetics experiments indicated the pseudo-second-order model displayed good correlation with adsorption kinetics data. The Crank model showed that the intraparticle solute diffusion is the rate-controlling adsorption step. Regeneration experiment result shows that the prepared MIL-101(Cr)/SA has excellent adsorption and desorption efficiencies.
研究领域:
化学工程
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材料科学
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环境科学
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2018
·
IF 3.927
Sushuang Li,Jianquan Luo,Jinxin Fan,Xiangrong Chen,Yinhua Wan
A green and mild method for aflatoxin B1 (AFB1) removal from food and drinking is highly required due to its high toxicity to human. In this study, membrane technology was attempted firstly to remove AFB1 via two protocols, membrane adsorber and biocatalytic membrane. Four polyvinylidene fluoride microfiltration membranes with different pore size were used to prepare membrane adsorber through successively coating polydopamine (PDA) and polyethyleneimine (PEI) on the membrane surface, and laccase was then loaded on the PDA/PEI-coated membrane to prepare biocatalytic membrane. Although biocatalytic membrane could remove AFB1 by both adsorption and enzymatic degradation, membrane adsorber outperformed thanks to its greater AFB1 removal efficiency (71%) and permeate flux (60 L·m −2 ·h −1 ) under gravity-driven flow-through mode. Hydrogen bonding together with electrostatic attraction was its main adsorption mechanism, and thus alkaline cleaning could fully desorb AFB1 from the membrane and further degrade detached AFB1. The contaminative apple juice was treated by such membrane adsorber, which could achieve a constant AFB1 removal for 7 reuse cycles.
研究领域:
环境科学
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食品科学
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化学工程
·
生物技术
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产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Miaoyuan Guo,Jianlong Ye,Chunyang Zheng,Jianqiang Meng
The combination of mixed-mode chromatography (MMC) and molecular imprinting technology (MIT) has been proven to be successful for protein separation, but suffered from cumbersome material preparation and limited performance. In this work, a new modification method marrying atom transfer radical polymerization (ATRP) and multicomponent reaction was proposed to simplify the preparation process. Using regenerated cellulose (RC) membrane as the substrate, immunoglobulin G (IgG) as the template protein and tryptamine as the ligand, a dual-recognition membrane adsorbers (MIM) was prepared by mild Ugi four-component reaction (Ugi-4CR) and surface initiated ATRP. Control the ATRP time is the key for surface imprinting. The static IgG uptake and selectivity of UGI membrane were 45 mg/mL and 1.8, respectively, while those of MIM-0.5 were 42.5 mg/mL and 14, indicating that the introduction of molecular imprinting technology significantly improved the selectivity of the membrane to IgG. The MIM-0.5 membrane retains the pH-dependent and salt-tolerant of HCIC. The dynamic flow-through results showed that the MIM-0.5 membrane could effectively separate IgG from IgG/BSA mixed solution with the purity of 88% and retained its bioactivity. This work demonstrated the feasibility of bonding HCIC and MIT to the membrane surface by Ugi-4CR and ATRP.
研究领域:
生物技术
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化学工程
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材料科学
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生物化学
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蛋白质分离
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DOI
PubMed
高影响因子
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