JOURNAL OF MEMBRANE SCIENCE
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2022
·
IF 10.53
Ke Bai,Senqing Fan,Yu Chen,Yilin Wang,Jiaojiao Chen,Zenghui Mai,Jingyun Liu,Lei Deng,Zeyi Xiao
A membrane adsorber with hierarchically porous HKUST-1 (HP-HKUST-1) immobilized in membrane pores has been fabricated by flowing synthesis. The X-ray diffraction (XRD) characteristics indicate that the structural integrity of the HP-HKUST-1 immobilized in the membrane pores can be kept after template agents are removed. Other characteristics prove the effective immobilization of HP-HKUST-1 in membrane pores. As a concept-of-proof, the adsorption for Congo red (CR) and Methylene blue (MB) is carried out to evaluate the adsorption performance of the membrane adsorber. The adsorption capacity for CR with 458 mg g -1 and MB with 241 mg g -1 can be obtained by HP-HKUST-1 powder, which is 2–3 times higher than those by HKUST-1 powder, owing to the mesopores with rich active adsorption sites. When the solution flows through the membrane adsorber, the adsorption rate for these adsorbates in the range of 0.049 g mg -1 h -1 and 0.129 g mg -1 h -1 can be obtained, which is 4–5 times higher than that by HP-HKUST-1 powder, owing to the enhanced mass transfer in the confined space of the membrane pores with micro or nano scale. After going through seven adsorption-desorption experiments, the membrane adsorber with HP-HKUST-1 immobilized shows remarkable repeatability.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Qi Zhao,Xiaoyue Liang,Chunju He
Solid phase extraction is an effective method for the separation and purification of nucleic acid molecules, which still suffers from high loss and low efficiency. Herein, a polyether sulfone membrane adsorber for deoxyribonucleic acid (DNA) separation and purification is constructed by combining vapor-induced phase separation (VIPS) technique and in-situ coupling reaction. More specifically, the slow phase separation during VIPS promotes the formation of reaction platform with loose bicontinuous structure, high porosity and surface segregation of poly (acrylic acid), which is subsequently highly aminated by in-situ coupling of polyethyleneimine. Significantly, the reversible binding of amine ligands to DNA is solely based on electrostatic interaction, which is regulated by medium pH, avoiding the requirement for additional binding agents as encountered by commercial silica matrices and dramatically reducing DNA loss. Consequently, the resulting membrane adsorber exhibits excellent DNA binding capacity of 293.3 mg·g −1 and improved dynamic DNA recovery efficiency of 85.2 %, far exceeding that of commercial silica matrices (55.5 %). This work provides a major breakthrough in the field of nucleic acid separation and purification, paving the way to construct next-generation solid phase extraction materials for biomacromolecules.
研究领域:
生物技术
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分子生物学
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2024
·
IF 8.4
Lidong Feng,Yubo Xu,Long-Fei Ren,Jiahui Shao
Nanoparticle doping in membranes is an ideal strategy for improving performance of aqueous-aqueous membrane extraction (AAME). However, its derived adsorption has not been investigated regarding performance enhancement/deterioration of phenol transmembrane mass transfer they might bring, especially in porous membranes. Therefore, supercapacitor-activated carbon (YEC-8)-doped (>30 mg/g) and silica-doped membranes (<0.1 mg/g) only with differentiated adsorption capacity were prepared to identify adsorption impact on phenol extraction from saline-wastewater. Surprisingly, membrane adsorption significantly inhibited phenol transmembrane mass transfer regardless of adsorption saturation rather than enhancement as we hypothesized. Compared to PVDF membrane, extraction performance of silica-doped membrane decreased by 24.0% at 2 g/L phenol. For YEC-8-doped membrane, its extraction performance even decreased by 40%-50% when facing multiple phenol concentrations. These results stated the important role of volatilization-diffusion in phenol transmembrane mass transfer in comparison with solution-diffusion. Membrane characterization and Hagen-Poiseuille model analysis demonstrated that membrane pore complexity would induce partial performance degradation. DFT calculation further confirmed that adsorption of gaseous phenol (−1.7292 eV) within membrane pores was primary limiting step in transmembrane mass transfer. Overall, this study elucidates transmembrane mass transfer pathway, process, and mechanism of phenol in AAME with nanoparticle-doped porous membrane for the first time.
研究领域:
环境科学
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化学工程
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DOI
高影响因子
FOOD CHEMISTRY
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2022
·
IF 9.231
Yanlei Li,Zhiming Gao,Jian Guo,Jinmei Wang,Xiaoquan Yang
Flavour is a crucial sensory element that determines the consumers’ preference for food and beverages. In this study, we determined the effects of complex gum arabic (GA) and tannic acid (TA) on the aroma release of flavour oil emulsions in vitro by simulating oral processing conditions. GA and TA were used to stabilize flavour oil emulsions. Visualization of in vitro retention using ex vivo porcine tongue, detection of aroma release in the model mouth, and sensory evaluation of flavour emulsions were performed to determine the effect of TA and GA. The results indicated that the retention of emulsions and the release of aroma compounds were modulated by TA and GA, which could be because of interactions that occurred between GA and TA in emulsions and mucins on the tongue. GA enhanced aroma release, whereas TA contributed to the retention or slow release of target aroma compounds.
研究领域:
食品科学
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感官科学
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DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2018
·
IF 3.716
Fan Hu,Zhanghui Wang,Baoku Zhu,Liping Zhu,Youyi Xu
Energy-efficient and time-saving process for recovery of hazardous dyes from wastewater is highly desired in dyeing industry. In this work, poly( N -vinyl imidazole) (PVI) gel-filled membrane adsorbers were developed for highly efficient recovery of dyes through adsorption filtration. The membrane adsorbers were fabricated via dip-coating of Nylon macroporous membranes in PVI solutions followed by quaternization crosslinking with p-xylylene dichloride (XDC). Physicochemical characterizations indicated that PVI gel was successfully filled and fixed inside the Nylon matrix. In optimized conditions. The treating capacity of membrane adsorbers to typical dye sunset yellow (25 ppm of the feed concentration) reached up to 197 mg/g with the removal ratio >99%. Both the treating capacity and the removal ratio were kept steady even when the permeation flux was as high as 1000 L/m 2 h. The membrane adsorbers developed in this work were able to not only remove anionic dyes from water, but also separate anionic dyes from cationic ones. The zeta potential and adsorption tests showed that the electrostatic interaction between PVI gel and dye molecules was responsible for the high removal efficiencies to anionic dyes. The membrane adsorbers can be regenerated effectively with NaOH solution and demonstrated good stability in both acidic and alkaline conditions.
研究领域:
环境科学
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材料科学
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化工工程
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Qian Wu,Jinxin Fan,Xiangrong Chen,Zhenzhou Zhu,Jianquan Luo,Yinhua Wan
Aflatoxins as toxic substances produced by microorganisms widely existed in food crops and detoxification of aflatoxins is highly desired to avoid their leaking into the environment. Herein, a novel combination strategy of metal organic frameworks (MOFs) and porous membrane was used to prepare membrane adsorbent for aflatoxin B1 (AFB1) removal. Firstly, the MOFs particles were readily fixed on a porous membrane by reverse filtration. Subsequently, polydopamine (PDA) coating and further charged polymer grafting were employed for sealing the MOFs particles. By systematically studying four kinds of MOFs particles for AFB1 adsorption, the MIL-100 and the resultant MIL-100 loaded membrane outperformed the other MOFs materials. Through comprehensively evaluating five different sealing approaches, it was found that the charge of the grafted polymers on the membrane was critical for AFB1 adsorption. The PDA/alginate dialdehyde (ADA) modified MIL-100 loaded membrane prepared with PDA coating and ADA grafting for 30 min, could achieve the highest AFB1 removal efficiency of 76.4% and the membrane stability was greatly improved, meanwhile the water permeate flux was barely affected by the additional layers. A good reusability could be realized by a facile desorption process and the AFB1 removal efficiency kept at 61.8% after five reuse cycles. When dealing with real corn juice, the AFB1 removal efficiency in flow-through mode was lower than that obtained in dipping incubation mode, because severer membrane fouling occurred during dynamic adsorption which blocked the adsorption sites on the membrane. The present work not only demonstrated a reliable and effective approach to synthesize robust MOFs-loaded membrane for AFB1 removal, but also offered new insights into micropollutant removal with MOFs derived materials.
研究领域:
食品科学
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环境科学
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材料科学
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高影响因子
Journal of Materials Chemistry B
·
2018
·Vol. 6
·期 11
·1640-1649
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IF 4.776
M. Kamran Khan,Jianquan Luo,Zhaoshuai Wang,Rashid Khan,Xiangrong Chen,Yinhua Wan
Alginate dialdehyde (ADA), a biocompatible polymer, was used as an intermediate layer on a nylon membrane to readily fabricate cation exchange (CEX), metal-affinity (Me-affinity), histidine-affinity (His-affinity) and peptide-affinity (Pep-affinity) membrane adsorbers without any organic solvent usage. All the membrane adsorbers exhibited a high selectivity in the fractionation of a IgG (immunoglobulin)/HSA (human serum albumin) mixture. Along with a high purity of 100%, a high IgG binding capacity of 30, 24, 21 and 28 mg mL−1 (membrane volume) was achieved by the CEX, Me-affinity, His-affinity and Pep-affinity membrane adsorbers in flow-through mode respectively, which is superior to those of the reported membrane adsorbers. Furthermore, the CEX and Pep-affinity adsorbers were tested for the separation of IgG from human plasma solution. The carboxylic groups along with the peptides on the Pep-affinity adsorber captured IgG synergistically with a higher recovery and purity (99% and 98.6%). This synergetic adsorber showed a qmax and dynamic binding capacity (DBC) of 138.4 and 38.7 mg mL−1 respectively for IgG binding which was somewhat higher than that of the reported protein A agarose (having qmax and DBC of 84 and 24.4 mg g−1 respectively). The present work indicated that the ADA layer not only activated the membrane surface to attach various adsorptive ligands under mild conditions, but also reduced non-specific adsorption. Due to the versatile linking function and green reaction conditions, the ADA coating on the nylon membrane is promising for the preparation of diverse membrane adsorbers.
研究领域:
生物工程
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材料科学
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分离技术
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DOI
PubMed
高影响因子
MACROMOLECULAR MATERIALS AND ENGINEERING
·
2019
·Vol. 304
·期 6
·1800790
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IF 3.038
Lanfang Liu,Jianquan Luo,Yinhua Wan,Xiangrong Chen,Yuanpeng Wu
Mussel-inspired membrane adsorber with thiol ligand (SH-membrane adsorber) is prepared by polydopamine-assisted poly(ethylene imine) grafting and subsequent thiolation modification for efficient removal of patulin. The effects of temperature, contact time, pH, and initial patulin concentration on the adsorption capacity of the membrane adsorber are investigated. The results show that the SH-membrane adsorber is effective to remove patulin. The adsorption capacity of the membrane can reach 1245.11 µg g −1 for patulin. In static adsorption tests, the adsorption kinetic and equilibrium data are well fitted by the pseudo-second-order kinetic model and Freundlich isotherm model, respectively, meaning that the adsorption process is a multilayer chemical adsorption. The SH-membrane adsorber can be recovered by l -cysteine, and the removal efficiency of patulin is maintained at about 89.23% after eight reuse cycles, compared to the 17.33% of control membrane. These results demonstrate that the SH-membrane adsorber has a potential application for patulin removal.
研究领域:
食品科学
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环境工程
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生物化学
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DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Samah Attia Algharib,Ali Dawood,Kaixiang Zhou,Dongmei Chen,Chao Li,Kuiyu Meng,Muhammad Kashif Maa,Saeed Ahmed,Lingli Huang,Shuyu Xie
Due to the poor solubility and permeability of rifaximin (RFX), it is not effective against intracellular pathogens although it shows strong activity against most bacteria. To develop an effective mucoadhesive drug delivery system with a targeted release in bacterial infection site, RFX-loaded chitosan (CS)/carboxymethyl-chitosan (CMCS) nanogel was designed and systematically evaluated. FTIR, DSC, and XRD demonstrated that the nanogel was formed by interactions between the positively charged NH 3 + on CS and CMCS, and the negatively charged COO on CMCS. RFX was encapsulated into the optimized nanogel in amorphous form. The nanogel was a uniform spherical shape with a mean diameter of 171.07 nm. It had excellent sustained release, strong mucin binding ability, and pH-responsive properties of quicker swelling and release at acidic pH. It showed low hemolytic ratio and high antioxidant activity. The present investigation indicated that the CS-nanogel could be potentially used as a promising bacterial responsiveness drug delivery system.
研究领域:
药剂学
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生物材料
·
感染性疾病
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DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Qi Zhao,Xiaoyue Liang,Xueyu Zhang,Chunju He
Ion exchange membrane adsorbers, an alternative to overcome the bottleneck of present deoxyribonucleic acid (DNA) solid-phase extraction material, still suffer from scarce binding capacity and uncontrollable recovery efficiency. Herein, inspired by mussel adhesion combined with in-situ coupling technique, a silane-modulated biomimetic amination strategy is proposed to construct an anion-exchange membrane adsorber for efficient DNA separation. The coupling of polyethyleneimine to the biomimetic interlayer formed by the co-coating of pyrogallol and 3-glycidoxypropyltrimethoxysilane onto polyethersulfone membranes provides high coverage of DNA-binding ligands for the resulting membrane adsorber. Furthermore, its surface charge properties are tailored by the tunable content of epoxy groups in the biomimetic interlayer, resulting in the pH-responsive reversible DNA binding capacity. Consequently, the resulting membrane adsorber exhibits unprecedented DNA adsorption capacity (396.2 mg g −1 ), which is renewable and requires no external binding agent. More importantly, this membrane adsorber in the form of spin columns achieves outstanding DNA recovery efficiency up to 88 %, which is 32 % improvement over commercial silica matrices. This research provides a new perspective on the design of novel ion exchange membrane adsorbers and holds promise for the low-loss, high-efficiency downstream separation and purification processes of biomacromolecules.
研究领域:
生物化学
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材料科学
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分子生物学
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Linlin Huang,Haoyu Zhang,Yanqiong Tan,Wenqin Guo,Jinping Fan,Xiao He,Bo Li,Hongbo Liu,Zhishu Tang,Yue Zhang,Huaxu Zhu
Essential oils (EO) constitute a class of volatile oily liquids with a wide range of applications in pharmaceuticals, foodstuffs, and household chemicals. However, because of their low contents and complex compositions in plants, especially that of some components containing hydrophilic groups that can exist in the form of dissolved oils, their extraction and separation are often difficult. In this study, the membrane-enrichment process of EOs is systematically analyzed by separating nine representative oil/water emulsions used in traditional Chinese medicine using an alumina ceramic (AC) membrane. Owing to the differences in oil content and main component properties of different herbs, AC membranes exhibit different fluxes and oil-rejection rates for different EO emulsion. The highest oil-interception rate, of up to 79.55 %, is exhibited for Eugenia caryophyllata Thunb. (EcT) EO. The droplet size and charge of the emulsions dominate the membrane-separation process. The AC membrane intercepts aldehydes, ketones, and ethers through strong adsorption, whereas highly hydrophobic olefins are intercepted via repulsion. In addition, a carbon layer is coated on the AC membrane to block the contact between alumina and EO components. The specific selective retention of volatile oil components by the AC membrane is verified. The components of EcT EO, enriched by the AC membrane, show 99.4 % similarity to those obtained by traditional steam distillation, while exhibiting comparable antibacterial activity. This study provides new insights into membrane-material design for EO enrichment and offers guidance for matching EOs with suitable membrane materials.
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高影响因子
AICHE JOURNAL
·
2021
·Vol. 67
·期 8
·e17272
·
IF 3.993
Boya Qiu,Senqing Fan,Yu Chen,Jiaojiao Chen,Yilin Wang,Yinan Wang,Jingyun Liu,Zeyi Xiao
A micromembrane adsorber with deep-permeation nanostructure (DPNS) has been successfully fabricated by flowing synthesis. The nanoparticles are in-situ assembled in membrane pores and immobilized in each membrane pore along the direction of membrane thickness. The nanoparticles with a lower size and thinner size distribution can be achieved owing to the confined space effect of the membrane pores. As a concept-of-proof, the nano ZIF-8 and ZIF-67 are fabricated in porous membrane pores for methyl orange (MO) and rhodamine B (RhB) adsorption. The adsorption rate is increased significantly owing to the enhanced contact and mass transfer in the confined space. The adsorption capacity for the RhB is also increased, since the size of the nanoparticles assembled in membrane pores is smaller with more active sites exposed. This micromembrane adsorber with DPNS has good reusability and can provide a promising prospect for industrial application.
研究领域:
材料科学
·
环境工程
·
化学工程
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高影响因子
危险品化学品经营许可证（带存储）