ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Shuting Shen,Chengfei Liu,Wenxin Fan,Kunyan Sui
Ionic skins (I-skins) hold significant potential for mimicking the complex sensory functions of human skin. However, they suffer from unstable sensing performance because the water content and temperature of I-skins are susceptible to the surrounding environment. Here, a self-detection sensing mechanism designed to address this critical issue, ensuring stable perception of multiple stimuli in I-skins, is introduced. It is demonstrated that gradient polyelectrolyte (GP) conductors possess two parameters—resistance and self-induced potential—that are responsive to temperature and water content. Through establishing the functional relations of resistance and potential against temperature and water content based on the Nernst−Planck and Arrhenius equations, respectively, the temperature and water content of resulting GP I-skins can be self-detected/calculated in real-time from the measured resistance and potential signals. Such self-detection capability allows GP I-skins not only to self-calibrate their sensing parameters for accurate detection of mechanical stimuli across varying environmental conditions but also to discern surrounding temperature and humidity in accordance with Flory−Rehner theory. This self-detection sensing mechanism offers a powerful tool for developing I-skins capable of stable perception of multiple stimuli in changing environments without complex and undesired encapsulation.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Wen Yu,Xinke Kong,Chengcheng Gu,Panpan Gai,Feng Li
We proposed an enzymatic biofuel cells (EBFCs)-based biosensing platform with visual self-checking function for the ultrasensitive detection of Vibrio parahaemolyticus (Vp) with low detection limit of 2 CFU mL −1 (S/N = 3). In detail, the as-proposed biosensor was composed of the aptamer/glucose dehydrogenase/poly-thionine/carbon nanotubes/gold nanoparticles bioanode , the mediated prussian blue (PB)/ prussian white (PW) electrode with the visual self-checking function and the bilirubin oxidase/carbon nanotubes (BOD/CNTs) biocathode. Initially, the successful electron transfer from the bioanode to the PB/PW electrode could produce a high open circuit voltage ( E OCV ), accompanying with the reduction of PB to PW. Once in the presence of the target Vp , it was recognized and captured by the aptamer at the bioanode, and the E OCV obviously decreased while the color of the mediated electrode would return back to blue. Thus, the signal E OCV difference could be checked by color change, which could to a great extent avoid possible false-positive readout. In addition, the self-checking function could be recovered when connected with BOD/CNTs electrode. Overall, this work presented a prototype of an on-site tool with visual self-checking function.
研究领域:
生物传感技术
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微生物学
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电化学
✓ 已验证
产品关联
DOI
高影响因子
Biosensors-Basel
·
2023
·Vol. 13
·期 2
·180
·
IF 5.4
Sheng Li,Wenlong Guo,Minmin Xiao,Yulin Chen,Xinyi Luo,Wenfei Xu,Jianhua Zhou,Jiasi Wang
Rapid and sensitive detection of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for early diagnosis and effective treatment. Nucleic acid testing has been considered the gold standard method for the diagnosis of COVID-19 for its high sensitivity and specificity. However, the polymerase chain reaction (PCR)-based method in the central lab requires expensive equipment and well-trained personnel, which makes it difficult to be used in resource-limited settings. It highlights the need for a sensitive and simple assay that allows potential patients to detect SARS-CoV-2 by themselves. Here, we developed an electricity-free self-testing system based on reverse transcription loop-mediated isothermal amplification (RT-LAMP) that allows for rapid and accurate detection of SARS-CoV-2. Our system employs a heating bag as the heat source, and a 3D-printed box filled with phase change material (PCM) that successfully regulates the temperature for the RT-LAMP. The colorimetric method could be completed in 40 min and the results could be read out by the naked eye. A ratiometric measurement for exact readout was also incorporated to improve the detection accuracy of the system. This self-testing system is a promising tool for point-of-care testing (POCT) that enables rapid and sensitive diagnosis of SARS-CoV-2 in the real world and will improve the current COVID-19 screening efforts for control and mitigation of the pandemic.Keywords:SARS-CoV-2;self-testing;reverse transcription loop-mediated isothermal amplification
研究领域:
病毒学
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医学诊断
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2025
·
IF 7.3
Xianliang Li,Yawei Shao,Zhihao Chen,Yanqiu Wang,Junyi Wang
In this study, a fluorescence and Fe 3+ ions-responsive cerium-based metal organic framework is decorated on phytic acid-glucose hydrothermal copolymer-coated montmorillonite (MMT@CP@Ce-MOF) nanocontainer, which was developed for Q235 carbon steel's corrosion protection and detection in solution, waterborne epoxy coatings (WEP), and solvent epoxy coatings (EP). In the solution phase, the corrosion detection ability of Q235 carbon steel was introduced, relying on the Fe 3+ ions-responsive characteristic of MMT@CP@Ce-MOF. In the coating phase, WEP and EP with good barrier effect, active anti-corrosion, self-detection, and good mechanical performance were fabricated by integrating MMT@CP@Ce-MOF nanocontainers. The EIS results indicated that 2D MMT@CP@Ce-MOF based composite coating showed better anti-corrosion performance (the |Z| f= 0.01Hz value of EP-MMT@CP@Ce-MOF and WEP-MMT@CP@Ce-MOF remained 1.33 × 10 9 Ω·cm 2 and 2.71 × 10 8 Ω·cm 2 , respectively, far higher than the bare coating) after 40 d immersion. At the same time, the Ce-MOF nanosensor could accurately reflect the occurrence of corrosion at the coating damage sites. Furthermore, high adhesion force (2–3 times higher than bare coating) and results of coating fracture surface showed that homogenously incorporated MMT@CP@Ce-MOF could improve the composite coating mechanical properties by chemical interaction with the epoxy polymer.
研究领域:
材料科学
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腐蚀工程
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纳米技术
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表面工程
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涂层技术
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传感器
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）