ACS Applied Polymer Materials
·
2024
·
IF 4.4
Yarui Hou,Xiaohui Wang,Changli Ma,Zeqi Liu,Ran Li,Yiyuan Fan,He Cheng,Bin Yang,Kai Li,Qingye Liu
Crystalline aggregates are widely present in various organisms. Regulation of nanostructures is of vital importance to the revelation of life secrets as well as material fabrication. As a representative, chitosan displays polymorphic structures. In tendon chitosan, four polymer chains are packed into an orthorhombic cell, where the antiparallel neighboring chains are linked by two sets of N2···O6 hydrogen bonds, and water molecules are connected with N2, O3, and O5 as well as O6 atoms via hydrogen bonds to stabilize the hydrated structure. The transition from hydrated to anhydrous allomorphs, however, usually involved high-temperature annealing or multistep concentrated acid hydrolysis, which weakened the sustainability of chitosan. To address these issues, we proposed a more convenient strategy to achieve the polymorphic transitions under mild conditions. By subjecting chitosan microgels (CSM) to normal freezing treatment, the hydrated aggregates could be transferred into the anhydrous form. The X-ray diffraction (XRD) results clearly demonstrated that both the (020) and (200) diffraction peaks centered at 2θ = 10 and 19.8° gradually disappeared, while the (110) peak at 2θ = 14.8° indicated the occurrence of anhydrous crystals. Upon freezing, the water molecules that were inserted into the hydrated crystals were removed. Meanwhile, under the effects of N2···O6 intermolecular hydrogen bonding and hydrophobic association, the adjacent polymer chains reorganized into new microcrystalline domains. Moreover, the CSM particles exhibited a strong tendency for self-association during this process. By introducing CSM into the oil/water mixture system to form a Pickering emulsion, the resultant macroporous materials could be used as the oil absorbent through subsequent lyophilization. This work provides a different way to facilely regulate the microcrystalline structure of chitosan in a controllable manner, facilitating the construction of more functional materials.
研究领域:
材料科学
·
生物学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SURFACTANTS AND DETERGENTS
·
2015
·Vol. 18
·期 3
·421-428
·
IF 1.685
Xu Wenwen,Zhang Qian,Wei Hongtu,Qin Jieqiong,Yu Li
The self-aggregation behavior of catanionic surface active ionic liquids (SAIL), 1-alkyl-3-methylimidazolium alkyl sulfates, [C 4 mim][C 16 SO 4 ] and [C 6 mim][C 14 SO 4 ], in aqueous solutions was explored by several techniques. These results were analyzed together with the concerning data of [C 8 mim][C 12 SO 4 ] reported previously. The feature of these SAIL is that the total carbon number of the hydrophobic chains is kept constant, while only the length of the two hydrocarbon chains varies. Because of the different intermolecular and intramolecular interactions, the hydrophobic interaction of asymmetrical SAIL is enhanced, which explains the minimal CMC value of [C 4 mim][C 16 SO 4 ]. Thermal motion of hydrocarbon chains at the air–water interface leads to higher A
min and lower Γ max values with the increasing asymmetry of two hydrophobic chains. The conductivity measurements reveal that the micellization process is spontaneous and entropy-driven in the studied temperature range. This work indicates that the symmetry of alkyl chains can influence the aggregation behavior of [C
n
mim][C
m
SO 4 ] in aqueous solutions.
研究领域:
化学
·
物理化学
·
胶体与界面化学
✓ 已验证
DOI
高影响因子
Bioactive Carbohydrates and Dietary Fibre
·
2015
·
IF 0
Wei Xu,Weiping Jin,Chunlan Zhang,Hongshan Liang,Bakht Ramin Shah,Bin Li
Self-aggregation behaviors of κ-carrageenan/lysozyme (CRG/Ly) complex inducing by intrinsic and extrinsic factors were investigated form macro and micro aspects, including the ratio, pH, temperature and salt. High Ly content promote aggregation behavior of CRG/Ly complex, while CRG played a suppressive role. Except for CRY5, the complex displayed nano-size distribution. Both CRG addition and the self-aggregation behavior could enhance the thermal stability of Ly. Low ζ-potential induced by pH made the CRG/Ly complex easy to self-aggregate into structure with large size due to the gradual association of complex to form lager interpolymeric complexes. The tunable process means to control the dissociation and association behavior between interpolymeric complexes and soluble complex by pH. All systems shared high NaCl tolerance and presented stable transmittance. Heat-induced self-aggregation exhibited a temperature and polymers ratios dependant manner. The mechanisms of environment induced self-aggregation into interpolymeric complexes reflected the re-balanced physical interaction when they suffered from any treatment. Controlling and regulating self-aggregation behavior of protein/polysaccharide system could enrich the soft structures from food respective and also provide practical theory for food process.
研究领域:
食品科学
·
生物大分子相互作用
·
软物质结构
✓ 已验证
DOI
CARBOHYDRATE POLYMERS
·
2015
·
IF 4.074
Huiqiong Yan,Xiuqiong Chen,Jiacheng Li,Yuhong Feng,Zaifeng Shi,Xianghui Wang,Qiang Lin
In this research, the systematic evaluation of fundamental properties of the alginate derivative (Ugi-Alg) synthesized by the Ugi reaction is presented. The structure of Ugi-Alg with the degree of substitution of 23.24% was confirmed by FT-IR and 1 H NMR spectrometers. The X-ray diffraction (XRD) results indicate the amorphous structure and the crystal structure change of Ugi-Alg, which is possibly ascribed to the destruction of inter- and intra-molecular hydrogen bonding interactions during the Ugi reaction. From thermal gravimetric analysis (TGA) and fluorescence spectrophotometer, Ugi-Alg shows high thermal stability and good amphiphilic functionality with the critical aggregation concentration of 0.07 g/L in 0.15 mol/L aqueous NaCl solution. Transmission electron microscope (TEM) image and dynamic light scattering (DLS) reveal that stable Ugi-Alg self-aggregated micelle with the average size of 162.3 nm and ζ potential at about −31.7 mV could form in the aqueous media, which presents tremendous potential in pharmacology and tissue engineering.
研究领域:
材料科学
·
药学
✓ 已验证
DOI
高影响因子
FUEL
·
2024
·
IF 6.7
Shuoshuo Song,Changjun Li,Wenlong Jia,Fan Yang,Yuanrui Zhang,Xuehua Zhang,Nobuo Maeda,Huan Xiao
The formation of emulsions is undesirable yet unavoidable in petroleum production. Researchers suggest that asphaltenes adsorb at the oil/water interface, forming a protective film that stabilizes emulsions. This study investigates how asphaltene aggregates, formed through intermolecular interactions, affect emulsion stability and the properties of the oil/water interface. First, the effects of asphaltene concentrations, components, and temperatures on emulsion stability and the association state of asphaltenes were explored using the bottle test method and dynamic light scattering, respectively. The promotion of asphaltene aggregation by higher asphaltene concentrations and liquid paraffin content was confirmed by comparing the average size of aggregates, while higher temperatures were found to inhibit aggregation. Higher temperatures destabilize emulsions containing asphaltenes by increasing water droplet collisions, whereas higher asphaltene concentrations and liquid paraffin content stabilize emulsions. Subsequently, the effects of these conditions on expansion modulus were thoroughly investigated using the pendant drop technology. Pendant drop experiments demonstrate that increasing asphaltene concentration, along with the introduction of liquid paraffin, enhances asphaltene aggregation, thereby reinforcing the structural stability of the interfacial film. Spinning drop experiments were conducted to obtain dynamic interfacial tension (IFT) and analyze the adsorption behavior of aggregates at the oil/water interface. The adsorption process of asphaltenes driven by intermolecular interactions, occurs in three regimes: a short-term diffusion-controlled process, a transition process, and a long-term low-speed descent process, referred to as Regimes I, II, and III. The diffusion coefficient in Regime I increases with temperature, while the equilibrium IFT in Regime III decreases with temperature. In Regime II, adsorbed asphaltene aggregates from Regime I tend to prevent further adsorption, reducing the rate of dynamic IFT decrease. In Regime III, dynamic IFT decreases slowly, primarily due to the continued adsorption of asphaltene aggregates into the sublayer and their subsequent reconfiguration. These findings have significant implications for improving the understanding of oil/water interface properties and emulsion behavior in oil production, transportation, and refining systems.
研究领域:
石油工程
·
界面化学
·
胶体科学
✓ 已验证
产品关联
DOI
高影响因子
NANOTECHNOLOGY
·
2021
·Vol. 32
·期 37
·375603
·
IF 3.874
Chundong Liu,Jia Li,Fengcai Lei,Yisheng Wei,Zhen Li,Chao Zhang,Qianqian Peng,Jing Yu,Baoyuan Man
The surface-enhanced Raman spectroscopy (SERS) has attracted much attention due to the powerful capability of quantificational analysis. Nowadays, most of the enhancement effect by SERS substrate is provided by the 'hot spots' occupying relatively small space. When the amount of analyte is too low, it is difficult to ensure that all the probe molecules can be placed into the 'hot spots', which is a headache in SERS quatification. In order to solve this problem, we have developed a structure of CuO nanowires/Ag nanoparticles with wettability capacity difference, which can aggregate molecules in water and oil simultaneously under two different mechanisms. The limit of detection and enhancement factor of this structure are estimated as 10−15 M and 1.55 × 1011 respectively (for rhodamine 6G, R6G). In a proof-in-principle experiment of sewage detection, it successfully achieved the aggregation and additional enhancement of both the R6G molecules in aqueous solution and thiuram molecules in toluene, realizing efficient and accurate Raman detection.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Zixian Yu,Yiren Cao,Lei Wang,Youli Tian,Rui Zou,Keer Chen,Weiwen Liu,Qiang Zhang,Qingjiang Wang,Baohong Zhang,Chengxi Cao
Monoclonal antibodies (mAbs) are widely used in tumor and autoimmune disease therapy and clinical diagnosis, but they suffer from self-aggregation, particularly dimer formation, impacting their stability, efficacy, and potentially causing severe allergies. Traditional methods for detecting mAb dimers, such as TEM, AUC, DLS, SEC, and CE, are limited by low throughput, high costs, and qualitative data, making them unsuitable for large-scale sample assays in biopharmaceuticals industry as well as antibody research. To address these issues, we developed a facile method of protein cross-linking gel electrophoresis with online intrinsic fluorescence imaging (PC-GE-IFI) for self-aggregation and stability assays of mAbs. This method enables the real-time quantification of monoclonal antibody (mAb) monomers and dimers with exceptional sensitivity, characterized by low detection limits (monomer: 0.9 nM; dimer: 0.45 nM) and a broad dynamic range (monomer: 2.50–2500 nM; dimer: 1.25–1250 nM). Furthermore, the sample wells can be used as windows for the assay of precipitates formed by mAb aggregation. The method supports accurate assessment of mAb dimerization and monomer purity under various stress conditions, including thermal stress, mechanical agitation, and freeze–thaw cycles. Moreover, the method allows concurrent analysis of dimers and precipitates across multiple samples at different concentrations, while nonlinear fitting provides the dissociation constant (Kd) for monomer–dimer interactions, a critical parameter that aids in assessing aggregation propensity, and informs the design and development of mAb products The PC-GE-IFI method has great potential for development, quality control, and safety assessment of mAbs, bispecific antibodies, ADCs, and protein drugs.
研究领域:
生物技术
·
药物开发
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2021
·
IF 6.165
Jingyang Pu,Xiaoyu Gu,Mingliang Luo,Yun Bai
Stimuli-responsive poly(acrylamide-co-vinyl acetate)/alginate-based hydrogel particle (AIPNG particle) are obtained by free-radical polymerization of acrylamide monomer and vinyl acetate monomer which interpenetrates with branched polyethyleneimine (B-PEI)/alginate-based polyelectrolyte complex (PEC). The AIPNG particle is developed for reservoir conformance control in Ca-rich reservoirs. The AIPNG particle can swell 13 to 25 times its initial volume, and the equilibrium swelling ratio is dependent on brine type and concentration. The swelling and elastic modulus of the AIPNG particles are strongly influenced by salt in the aqueous solution. The release rate of B-PEI from B-PEI/alginate PEC structure, combining with the swelling ratio, the environmental temperature, and Ca 2+ concentration, determines the self-association time and rheological strength of the AIPNG gel. Preparation pH influences the protonation degree of B-PEI and subsequently affects the self-association behavior by delaying the intermolecular transamidation reaction between poly(AM-co-VA) acrylamide pendant groups and PEI nitrogens. With the component adjustments, the self-association starting time can be controlled between 2 and 16 h depending on temperature and swelling ratio. Ca 2+ , supported from environmental brine, can influence the self-association time and help reinforce the re-formed bulk gel by forming Ca-alginate bonds and creating a hard Ca-shell on the gel surface. Field trial results in Zhidan oilfield demonstrated the potential of AIPNG particle products in high-salinity/middle-temperature reservoirs which provided a new way for maintaining the oil production and reducing water-cut in the mature oilfields.
研究领域:
材料科学
·
石油工程
·
高分子化学
✓ 已验证
DOI
高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2020
·Vol. 32
·期 1
·190-201
·
IF 2.578
Jie He,Minglu Shao,Xiangan Yue,Tianqi Yue
In order to alleviate the contradiction between injectability of the profile control agent and its profile control performance, a novel core-shell heterogeneous structure colloidal particles (CSA) were synthesized, and the mechanism of self-aggregation plugging was proposed. Cross-linking inside the nanoparticles and chain-growth polymerization via capturing acrylamide in the aqueous phase result in the formation of core-shell heterogeneous structures as proved by TEM observation and XPS analysis. Moreover, CSA nanoparticles exhibit good hydrophilic properties, outstanding thermal stability and limited expansion capacity. Effects of different metal cations and surface group on the self-aggregation time of CSA nanoparticles were systematically studied. Results showed that divalent cations contributed to more significant aggregation of CSA nanoparticles in comparison to monovalent cations. The increasing cations concentration and valency decreased the thickness of electric double layer, which lead to a decrease in the zeta potential. Core flooding test shows that the injection of nanoparticles which diameter is much smaller that of pore-throats into the target reservoir can not only successfully enter the depth of porous media, but also effectively block the high permeability areas by the formation of self-aggregation particle clusters. This study provides a new method for the equilibrium between nanoparticles injectivity and in-depth profile control of nanoparticles.
研究领域:
石油工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Nano Energy
·
2025
·
IF 17.1
Jing Wang,Zhaoyue Xia,Heng Yao,Hui Yang,Qilong Zhang
In this study, a high-performance and swell-resistant triboelectric nanogenerator (TENG) has been proposed, specifically designed for high-humidity environments to meet the challenges of swelling problem and performance degradation. The composite film was fabricated by combining self-aggregation crosslinking reactions for polyvinyl alcohol (PVA) through ammonium persulfate (APS) initiations and interface physicochemical structure regulations for polyacrylonitrile (PAN) support layer. The treatment of PAN films with sodium hydroxide (NaOH) and tannic acid (TA) significantly enhances their electron affinity and electrical properties. Furthermore, the film exhibits superior swelling resistance, mechanical strength, and triboelectric characteristics. Owing to higher positive surface potential and optimized interface modulation, the constructed TENG using 8 wt% PVA initiated by 1.25 wt% APS spined on modified PAN support layer (PA 8–1.25 NTP-TENG) presents excellent stability and performance, with the I SC density reaching 180.9 mA·m −2 , voltage of 1396 V, and power density of 89.66 W·m −2 . Practically, the TENG successfully powered electronic devices and generated signals through human movements, harvesting biomechanical energy. Additionally, a self-powered ethanol pervaporation dehydration detector was developed, showcasing excellent permeability selectivity and stable performance in high humidity and elevated ethanol concentrations. Notably, in the dehydration process, the concentration of ethanol after membrane treatment achieves exceeding 99.99 %. This work introduces a novel strategy for enhancing the electrical properties of TENGs, providing valuable insights into material interface regulation mechanisms during energy conversion.
研究领域:
材料科学
·
能源转换技术
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
·
2018
·Vol. 135
·期 5
·2903-2913
·
IF 2.209
Wang Yujie,Wu Hui,Wang Jiuxia,Lou Pengxiao,Zhao Yang,Bai Guangyue
Thermodynamics of interaction between cationic gemini surfactants [C 12 H 25 (CH 3 ) 2 N(CH 2 ) s N(CH 3 ) 2 C 12 H 25 ]Br 2 , ( s = 2, 6 or 10, assigned as C 12 C s C 12 Br 2 ) and sodium deoxycholate (NaDC) in aqueous solution has been investigated by isothermal titration calorimetry (ITC), fluorescence and turbidity measurements. The critical micelle concentrations for NaDC-rich mixture (cmc mix,12-s-12 ) were determined by fluorescence method. The cmc mix,12-s-12 values are much smaller than those for pure C 12 C s C 12 Br 2 surfactants, and decrease as the spacer length ‘s’ increases. There is a strong synergistic effect between two surfactants in the NaDC-rich region. In the higher C 12 C s C 12 Br 2 concentration range above cmc mix,12-s-12 , we did obtain from ITC and turbidity measurements the critical parameters for different events that occur as the C 12 C s C 12 Br 2 concentration increases, including the critical concentrations ( C P , C R , C M ) of formation and redissolution for LC of the mixed C 12 C s C 12 Br 2 /NaDC systems and transition to gemini-rich micelles. In comparison with the mixed C 12 C s C 12 Br 2 /NaC systems reported with sodium cholate (NaC), the mixed systems with NaDC have lower cmc mix,12-s-12 , C P , C R and C M , and thus different self-aggregation processes are well controlled by surfactant concentration and molar fraction. Importantly, ITC allowed us to directly measure the enthalpy changes corresponding to different self-aggregation processes—redissolution enthalpy (∆ H R ) of LC of mixed surfactants and transition enthalpy (∆ H M ) from LC to gemini-rich micelles. Eventually, we discussed the cross-linking effect on NaDC-rich micelles of the gemini surfactant (C 12 C s C 12 Br 2 ) with double hydrophobic chains and cationic head groups linked through a methylene spacer.
研究领域:
物理化学
·
表面活性剂科学
✓ 已验证
产品关联
DOI
高影响因子
ENERGY & FUELS
·
2021
·
IF 3.605
Xuechun Ding,Shengchao Wei,He Bian,Lijun Zhu,Daohong Xia
Despite the studies on asphaltene aggregation throughout few decades, the formation of asphaltene aggregates and subsequent deposition are still the biggest challenges in the oil industry. Especially, the role of porphyrins existing in oil naturally on asphaltene aggregation is not completely understood due to asphaltene’s and porphyrin’s special structures. Herein, we investigated the influence of tetraphenylporphyrin (TPP), nickel tetraphenylporphyrin (NiTPP), and vanadium tetraphenylporphyrin (VOTPP) on asphaltene aggregation by a multiscale approach, which provides an in-depth understanding of the role of porphyrins on asphaltene aggregation. UV–vis spectroscopy and fluorescence spectroscopy were performed to examine the self-aggregation of TPP, NiTPP, and VOTPP and the influence of porphyrins on the aggregation of asphaltene. The changes of stacking structures, microscopic structures, and particle size distributions of co-aggregates of asphaltenes with porphyrins were analyzed in detail via X-ray diffraction, inverted fluorescence microscopy, and granulometric distribution, respectively. The characterization results indicated that the aggregation ability of the porphyrins (TPP, NiTPP, and VOTPP) was stronger than that of asphaltene and porphyrins can promote the aggregation of asphaltene, which leads to the increase of the average aromatic sheet number, aggregation morphology, and particle size of asphaltene aggregates. Based on experimental analysis, the possible mechanism by which porphyrins promoted asphaltene aggregation was elucidated. This research provided new insights into the aggregation and disaggregation of asphaltenes.
研究领域:
石油化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）