ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Yibing Luo,Hao Wang,Yuning Liang,Ruijie Xie,Zixuan Wu,Yubin Zhou,Kai Tao,Shaowu Pan,Bo-Ru Yang,Yongqing Fu,Fei Liu,Fengwei Huo,Jin Wu
Stretchable multimodal electronic skin (e-skin) has attracted intensive research interest but faces great challenges related to strain interference, crosstalk issues, and integration of multiple sensitive materials. Herein, a stretchable and strain-isolated multimodal (SSIM) e-skin capable of concurrently and sensitively monitoring temperature, humidity, UV light, and oxygen, while also possessing self-compensation capability is developed. The SSIM sensing platform is created by chemically anchoring polyethylene terephthalate onto polydimethylsiloxane through silane treatment to form island-bridge structures. This method effectively isolates strain and improves interfacial adhesion, achieving a state-of-the-art low strain interference of 0.2% and an adhesion energy exceeding 300 J m − 2 (13.4 times that of the untreated material), ensuring the e-skin's stable operation even under dynamic stretching. To mitigate crosstalk and fabrication complexity, a single hydrogel film is employed to facilitate self-compensating multimodal sensing through various sensing mechanisms and physical isolations. The SSIM e-skin can simultaneously monitor several environmental and physiological signals with minimized crosstalk without interference from body movements. It enables remote respiration monitoring with wireless circuitry, highlighting its substantial potential in health monitoring, medical diagnostics, and neurorehabilitation.
研究领域:
生物医学工程
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材料科学
·
传感器技术
✓ 已验证
产品关联
DOI
高影响因子
BIOMACROMOLECULES
·
2015
·
IF 5.75
Shasha Wang,Fang Yuan,Kui Chen,Gaojian Chen,Kehua Tu,Hongjun Wang,Li-Qun Wang
Photodynamic therapy (PDT) is a promising singlet oxygen (1O2) mediated clinical treatment for many tumors. As the source of 1O2, oxygen plays an important role in the curative effect of PDT. However, the facts of photochemical depletion of oxygen and the intrinsic hypoxic microenvironment of tumors remain the major challenges. In this work, a novel photosensitizer carrier with oxygen self-compensating ability was designed for PDT. It was synthesized via chemical conjugation of hemoglobin (Hb) to polymeric micelles formed by triblock copolymers of poly(ethylene glycol)-block-poly(acrylic acid)-block-polystyrene (PEG-b-PAA-b-PS). The PEG-b-PAA-b-PS and resultant micelles in aqueous solution were comprehensively characterized by means of FTIR, 1H NMR, GPC, DLS, TEM, and fluorescence spectroscopy. The oxygen-binding capacity and antioxidative activity of the Hb conjugated micelles were evaluated via UV–vis spectroscopy. In addition, compared with the control micelles without Hb, the Hb conjugated photosensitizer carrier was able to generate more 1O2 and exert greater photocytotoxicity on Hela cells in vitro.
研究领域:
生物医学工程
·
肿瘤学
·
药剂学
✓ 已验证
DOI
PubMed
高影响因子
ACS Sensors
·
2025
·
IF 9.1
Zekai Huang,Guirong Wu,Yunyi Hu,Fei Lv,Ran Wang,Ruisi Shang,Yihang Wang,Xin Wang,Yunlong Zhao,Mengju Zhu,Chenyang Xue,Xiang Guo,Libo Gao
Accurate strain monitoring in environments with coexisting mechanical deformation and temperature fluctuations─such as solid rocket propellants, battery enclosures, and human ligaments─remains a longstanding challenge for flexible electronics. Conventional strain sensors suffer from significant thermal drift due to the intrinsic temperature dependence of their sensing materials, limiting their reliability in wireless and implantable applications. Here, we report an intrinsically temperature-insensitive, highly sensitive, wireless flexible strain sensor based on near-field communication technology. We innovatively design and demonstrate a flexible strain sensor that simultaneously achieves low temperature drift, high sensitivity, and passive wireless functionality. By combining two engineered materials with opposing temperature coefficients of resistance, the device achieves self-compensated thermal stability with a minimal temperature drift of 160 × 10–6 °C–1, eliminating the need for external calibration. It exhibits an exceptionally high gauge factor of 2415.76 across a wide strain range (0–80%), and enables wireless, battery-free strain readout over a distance of 3 cm. We demonstrate the sensor’s robust performance across three thermo-mechanically coupled scenarios: (1) strain monitoring within solid rocket motor propellant grains, (2) detection of volumetric deformation in lithium-ion batteries, and (3) ligament strain sensing in the human knee joint. This work provides a generalizable strategy for achieving thermal invariance in high-performance flexible strain sensors and expands the utility of passive wireless sensing in harsh and dynamic environments.
研究领域:
柔性电子学
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传感器
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无线通信
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材料科学
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生物医学工程
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机械工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS
·
2024
·Vol. 24
·期 10
·3232
·
IF 3.4
Zhenhao Sun,Yunjiang Yin,Baoguo Liu,Tao Xue,Qiang Zou
In recent years, hydrogel-based wearable flexible electronic devices have attracted much attention. However, hydrogel-based sensors are affected by structural fatigue, material aging, and water absorption and swelling, making stability and accuracy a major challenge. In this study, we present a DN-SPEZ dual-network hydrogel prepared using polyvinyl alcohol (PVA), sodium alginate (SA), ethylene glycol (EG), and ZnSO4and propose a self-calibration compensation strategy. The strategy utilizes a metal salt solution to adjust the carrier concentration of the hydrogel to mitigate the resistance drift phenomenon to improve the stability and accuracy of hydrogel sensors in amphibious scenarios, such as land and water. The ExpGrow model was used to characterize the trend of the ∆R/R0dynamic response curves of the hydrogels in the stress tests, and the average deviation of the fitted curvesϵ¯was calculated to quantify the stability differences of different groups. The results showed that the stability of the uncompensated group was much lower than that of the compensated group utilizing LiCl, NaCl, KCl, MgCl2, and AlCl3solutions (ϵ¯in the uncompensated group in air was 276.158, 1.888, 2.971, 30.586, and 13.561 times higher than that of the compensated group in LiCl, NaCl, KCl, MgCl2, and AlCl3, respectively;ϵ¯in the uncompensated group in seawater was 10.287 times, 1.008 times, 1.161 times, 4.986 times, 1.281 times, respectively, higher than that of the compensated group in LiCl, NaCl, KCl, MgCl2and AlCl3). In addition, for the ranking of the compensation effect of different compensation solutions, the concentration of the compensation solution and the ionic radius and charge of the cation were found to be important factors in determining the compensation effect. Detection of events in amphibious environments such as swallowing, robotic arm grasping, Morse code, and finger–wrist bending was also performed in this study. This work provides a viable method for stability and accuracy enhancement of dual-network hydrogel sensors with strain and pressure sensing capabilities and offers solutions for sensor applications in both airborne and underwater amphibious environments.
研究领域:
材料科学
·
传感器
·
可穿戴技术
·
生物医学工程
·
机器人技术
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）