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TALANTA · 2019 · IF 4.916

Preparation of monodisperse porous polymeric ionic liquid microspheres and their application as stationary phases for HPLC

Qiaohong Peng,Yue Wu,Hailin Cong,Youqing Shen,Khalid Mahmood,Bing Yu

In recent decades, ionic liquid-modified packing materials as stationary phases of high performance liquid chromatography (HPLC) have attracted widespread attention due to their comprehensive properties. In this work, monodisperse porous polymeric ionic liquid microspheres were directly prepared using a seeded emulsion polymerization method and applied as stationary phase of HPLC. The effects of porogen , monomer and crosslinker on the properties of porous P(IL-DVB) microspheres were investigated in detail. Porous P(IL-DVB) microspheres with good stability, monodispersity and relatively high specific surface area were selected as stationary phase to successfully separate benzene and its homologues, and nucleosides and alkaloids under reversed phase chromatography (RPLC) mode and hydrophilic interaction chromatography (HILIC) mode, respectively.

研究领域: 分析化学 · 材料科学 · 色谱学
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