JOURNAL OF POLYMERS AND THE ENVIRONMENT
·
2023
·
IF 5.3
Li Jing,Liu Wan,Jiang Ping
First, biocompatible temperature-responsive polymer chitosan- graft - N -isopropylacrylamide (CS- g -PNIPAm) synthesized via ATRP. Second, mugwort oil (MO) was encapsultated with CS- g -PNIPAm as shell materials to form long-term anti-bacterial agents and temperature responsive microcapsules. The CS- g -PNIPAm@MO (CSPN@MO) microcapsules were prepared via single coacervation method and solvent evaporation method. The chemical structures of CS 0.1 - g -PNIPAm 22 was confirmed by 1 H NMR and FTIR. And the copolymer micelles were characterized by UV, laser particle-size analysis, and TEM. The results indicated that the copolymer had temperature-responsive behaviors. The microcapsules were characterized by laser particle-size analyzers (LPSA), scanning electron microscopy (SEM), TG and anti-bacterial agents performance testing. The results showed that the average particle size of microcapsules was 0.28 μm, and the encapsulation efficiency and drug loading efficiency of MO reached 60.2 and 44.5%. After 48 h of release in media at different temperature (20, 40 and 60 °C) still sequestered 79.2, 92.2 and 96.1% of MO which approved the shell of microcapsules responded to different temperature. The morphology of CSPN@MO microcapsules revealed that the microcapsules presented smooth and firm structure. Antibacterial test for Artemisia argyi of CSPN@MO implied that the bacteriostatic rate reached 99.2 and 96.2% after 1 day and 10 days respectively. Bio-based macromolecular modification strategies can provide inspiration for the development of green microcapsules. Graphical Abstract
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
Polymers
·
2023
·Vol. 15
·期 17
·3585
·
IF 5
Xiaoyan Tang,Xun Guo,Yongchao Duo,Xiaoming Qian
With the continuous improvement of the standard of living, people are increasingly inclined towards natural, green, and environmentally friendly products. Plant-based products that are safe, natural, non-toxic, and beneficial to human health are often more favored. Poly(lactic acid) (PLA) is a polymer obtained through lactate polymerization using renewable plant resources such as corn and has excellent biocompatibility and biodegradability. It is widely used in the field of food packaging. Wormwood oil (WO) is an oil extracted from the stems and leaves of Artemisia plants, and it has broad-spectrum antibacterial properties. In this article, through electrospinning technology, wormwood oil was directly incorporated into PLA, giving the PLA nanofiber membrane antioxidant and antibacterial functions. Various parameters such as voltage (11 KV, 13 KV, 15 KV), spinning solution concentration (8%, 10%, 12%), distance (15 cm, 17 cm, 19 cm), and feeding rate (0.4 mL/h, 0.5 mL/h, 0.6 mL/h) were explored, and the resulting spun fibers were characterized. Through SEM characterization, it was found that when the spinning voltage was 13 KV, the spinning solution concentration was 10%, the distance was 17 cm, and the feeding rate was 0.5 mL/h, the nanofiber membrane had a smooth morphology without bead formation, with an average diameter of 260 nm. The nanofiber membrane was characterized using FTIR, TG, and SEM, confirming the successful incorporation of artemisia essential oil into PLA. The prepared antimicrobial nanofilm was subjected to antimicrobial testing, and the results showed that as the concentration of the essential oil increased, the inhibition zones also increased. When wormwood oil concentration was 4%, the diameter of the inhibition zone forStaphylococcus aureusincreased from 1.0 mm to 3.5 mm, while the diameter of the inhibition zone forEscherichia coliincreased from 2.0 mm to 4.5 mm.Keywords:electrospinning;nanofiber;poly(lactic acid);wormwood oil;natural antimicrobial
研究领域:
材料科学
·
生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2023
·Vol. 28
·期 15
·5889
·
IF 4.6
Yue Zhu,Teng Chen,Tingting Feng,Jiaojiao Zhang,Zejing Meng,Ning Zhang,Gang Luo,Zuhua Wang,Yuxin Pang,Ying Zhou
Nanoemulsion is a new multi-component drug delivery system; the selection of different oil phases can give it special physiological activity, and play the role of “medicine and pharmaceutical excipients all-in-one”. In this paper, we used glycyrrhizic acid as the natural surfactant, andBlumea balsamiferaoil (BB) and tea tree oil (TTO) as the mixed oil phase, to obtain a new green functional composite nanoemulsion. Using the average particle size and polydispersion index (PDI) as the evaluation criteria, the effects of the oil ratio, oil content, glycyrrhizic acid concentration, and ultrasonic time on the nanoemulsion were systematically investigated. The stability and physicochemical properties and biological activities of BB-TTO NEs prepared via the optimum formulation were characterized. The optimal prescription was BB: TTO = 1:1, 5% oil phase, 0.7% glycyrrhizic acid, and 5 min ultrasonication time. The mean particle size, PDI, and zeta potential were 160.01 nm, 0.125, and −50.94 mV, respectively. The nanoemulsion showed non-significant changes in stability after centrifugation, dilution, and 120 days storage. These nanoemulsions were found to exhibit potential antibacterial and anti-inflammatory activities. The minimal inhibitory concentration (MIC) of BB-TTO NEs againstEscherichia coli,Staphylococcus aureus, andPseudomonas aeruginosais 2975 μg/mL, 2975 μg/mL, and 5950 μg/mL, respectively. A lower level of inflammatory cell infiltration and proportion of fibrosis were found in the synovial tissue of AIA rats treated with BB-TTO NEs. These findings demonstrate that the BB-TTO NEs produced in this study have significant potential for usage in antibacterial and anti-inflammatory areas.Keywords:nanoemulsion;Blumea balsamiferaoil;tea tree oil;glycyrrhizic acid;anti-inflammatory;antibacterial
研究领域:
药剂学
·
纳米技术
·
生物科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF MICROENCAPSULATION
·
2020
·
IF 2.287
Lei Wang,Tingxiao Li,Binjie Xin,Yan Liu,Fuli Zhang
In recent years, wormwood has been successfully applied in various fields, such as flavouring agent, plant dye, insect repellent and medical product. Wormwood oil encapsulated microcapsules with continuous release behaviours would be further applied in the health care textiles. Here, wormwood oil encapsulated microcapsules with different core-wall materials ratios (gelatine: gum arabic: wormwood oil = 1:1:1, 1:1:2, 1:1:3, 1:1:4) were fabricated. The morphology and physicochemical properties of microcapsules were explored by scanning electron microscopy, ultrasonic wave particle size analysis, thermo gravimetric analysis and so on. The size analysis results indicated that the microcapsule diameter could be controlled less than 1 um. In vitro testing showed that the microcapsules were capable of extending the releasing period to over 6 days. The thermo gravimetric analysis proved that microcapsules had superior thermal stability compared with pure wormwood oil, showing broad application prospects in functional health care textile.
研究领域:
材料科学
·
纺织工程
·
药用植物学
✓ 已验证
DOI
高影响因子
Foods
·
2023
·Vol. 12
·期 15
·2969
·
IF 5.2
Xiaohan Meng,Ze Lv,Tianzhen Jiang,Yifei Tan,Shaoyang Sun,Jianguo Feng
In this work, a new food packaging film was synthesized via blending Artemisia oil (AO) into soybean protein isolate (SPI) and gelatin (Gel) for the postharvest storage of mango. The morphological architecture and mechanical properties of the films were characterized using scanning electron microscopy (SEM), atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FTIR), X-ray diffractometer (XRD), and other technologies. The results show that the prepared films had relatively flat surfaces with good mechanical properties. AO enhanced the light-blocking ability of the film, increased the hydrophobicity, and affected the moisture content and water solubility of the film to a certain extent. Furthermore, the antioxidant performance and antifungal (Colletotrichum gloeosporioides) capacity of the films increased with higher AO concentration due to the presence of the active components contained in AO. During mango storage applications, the films showed good freshness retention properties. The above results indicate that SPI–Gel films containing AO have excellent physicochemical and application properties and have great potential in the field of food packaging.Keywords:soybean protein isolate;gelatin;Artemisia oil;mango preservation;active packaging film
研究领域:
食品科学
·
植物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）