Sustainable Chemistry and Pharmacy
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2021
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IF 4.508
Yimin Wei,Zhe Jiang,Qiang Wang,Ping Wang,Yuanyuan Yu
Aqueous reactive dyeing of cotton is considered to be environmentally unfriendly owing to its high consumption of water and salt as well as large discharge of wastewater. However, the industrial applications of current alternative dyeing technologies are difficult to realize due to different problems such as poor dyeing quality, environmental pollution and high cost. Herein, we developed a dyeing approach using hydrophobic deep eutectic solvent (HDES) composed of thymol from thyme leaves and menthol from Mentho haplocalvx Bing (two natural compounds with pharmacological function) to overcome the problems caused by reactive dyeing of cotton. HDES dyeing approach could achieve excellent dyeing properties of cotton by optimizing water content, pick-up and concentration of alkali solution. Dye fixation kinetics of HDES dyeing system was studied based on Lagergren pseudo-first-order and pseudo-second-order dynamics models, compared with aqueous dyeing system. The cotton fabrics dyed in Thy-Men system exhibited excellent levelness, satisfactory colorfastness and color strength without addition of salt. Furthermore, HDES can be reused for 5 cycles of dyeing and the dyed fabrics displayed consistently high color strength values. This dyeing approach provides substantial reduction in wastewater emission and consumption of freshwater and chemicals, which has considerable potential for promoting sustainable development of the textile industry .
研究领域:
纺织科学
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环境科学
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化学工程
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产品关联
DOI
高影响因子
Agronomy-Basel
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2024
·Vol. 14
·期 11
·2566
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IF 3.3
Ao Li,Peiwen Zhu,Deyan Kong,Lei Wang,Anning Zhang,Yi Liu,Xinqiao Yu,Lijun Luo,Feiming Wang
Rice is a major global staple crop, but rising temperatures and freshwater shortages have made drought one of the most severe abiotic stresses affecting agriculture. Additionally, rice blast disease and brown planthopper infestations significantly impact yields. Therefore, developing water-saving, drought-resistant, high-yielding, and disease-resistant rice varieties is critical for sustainable rice production. The new water-saving and drought-resistant (WDR) rice ‘Huhan 1516’, bred using marker-assisted selection (MAS) and marker-assisted backcrossing (MABC) techniques, addresses these challenges. This variety is highly adaptable to drought-prone and water-scarce regions such as the Yangtze and Huai River basins. With its high yield, drought tolerance, and broad-spectrum resistance to rice blast (conferred by thePi2gene) and brown planthopper (BPH), ‘Huhan 1516’ is suitable for various farming systems and environments. Field trials show that this variety outperforms control varieties by 2.2% in yield and exhibits moderate resistance to both rice blast and brown planthopper. ‘Huhan 1516’ has been recognized as a new water-saving and drought-resistant rice variety by the state, and as a released cultivar, it has great potential for market promotion and application.
研究领域:
植物学
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遗传学
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农学
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DOI
高影响因子
Sustainable Materials and Technologies
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2024
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IF 8.6
Yu Shao,Jiawei Li,Dongming Qi
The conventional reactive dyeing of cotton fabrics creates a large amount of difficult-to-treat wastewater because of a low dye uptake and fixation and uses a large amount of dye-promoting electrolytes. In this research, cationic polyacrylate-encapsulated pigment-colored hybrid latex nanoparticles (PPNs) with three primary colors were synthesized by surfactant-free reversible addition–fragmentation chain transfer (RAFT) emulsion polymerization and then applied for the salt-free, near zero-discharge, and dyebath-recyclable cold pad dyeing of cotton fabrics with less water and energy consumption. The effect of the composition structure of PPNs on their color properties was systemically investigated, and the pad-dyed fabrics were compared with conventional salt-free dyeing samples. The results demonstrated that the PNNs pad-dyed cotton fabrics achieved satisfactory wet rubbing fastness (level 4), color strength , leveling property, hand feel, and air breathability. The color regulation and matching of the pad-dyed fabrics could be designed by adjusting the contents of three primary color PPNs due to their nanosize and intercompatibility, thus making it possible to rapidly manufacture colors. Furthermore, the PPNs dyebath proved to be recyclable for circular pad dyeing of cotton fabrics, remarkably reducing the wastewater discharge. Calculations showed that the comprehensive water, energy, and cost of 1 kg cotton fabrics could be reduced by about 88.9%, 58.5%, and 51.7%, respectively, compared with conventional pad dyeing with reactive dyes. This innovative salt-free and dyebath-recyclable circular cold pad dyeing technology not only significantly reduces pollution generated and wastewater discharged, but also uses less water and energy, providing a valuable reference for environment-friendly near zero-discharge and sustainable pad dyeing methods for textiles.
研究领域:
纺织工程
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环境科学
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材料科学
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产品关联
DOI
高影响因子
Current Nanoscience
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2024
·Vol. 21
·期 4
·757-765
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IF 1.4
Zirui Liu,Dan Li,Baofeng Zhao,Xifan Mei
BackgroundGouty arthritis, characterized by excruciating pain and discomfort, poses a significant burden on patients. While nanomedicines have shown promise in addressing this ailment, their complicated synthesis processes often involve potentially toxic procedures, contributing to adverse side effects in disease management.MethodsIn this study, we introduce a straightforward and elegant solution by utilizing easily prepared gold platinum (AuPt) nanoparticles for the treatment of gouty arthritis. The synthesis of these nanoparticles involves the use of gold and platinum precursors in conjunction with NaBH4, simplifying the manufacturing process. Experimental models of gout were established in both in vivo and in vitro settings through lipopolysaccharide and monosodium urate crystal induction.ResultsOur findings revealed that AuPt nanoparticles exhibited potent anti-inflammatory effects against gout. This effect was attributed to their ability to activate the Nrf2/HO-1 pathway, resulting in pain alleviation and the inhibition of inflammation, ultimately leading to the reduction of joint edema. With their uncomplicated synthesis and promising therapeutic potential, these simply prepared AuPt nanoparticles emerge as a compelling candidate for pharmaceutical intervention in the treatment of gouty arthritis.ConclusionThis approach not only holds the promise of delivering effective relief to patients but also minimizes the risk of unwanted side effects associated with complex nanomedicine synthesis processes.
研究领域:
药理学
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纳米医学
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炎症研究
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2024
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IF 18.5
Xiaoliang Qi,XinXin Ge,Xiaojing Chen,Erya Cai,Yajing Xiang,Hangbin Xu,Ying Li,Yulong Lan,Yizuo Shi,Hui Deng,Jianliang Shen
Diabetic foot ulcers (DFUs), a serious and increasingly common chronic issue among diabetics, often do not respond well to generalized treatment strategies. Hypoxia and the overexpression of reactive oxygen species (ROS), resulting in inflammatory dysregulation and subsequent imbalance in macrophage phenotypes, are critical factors contributing to the prolonged non-healing of DFU wounds. These two issues often interact in a continuous, problematic cycle. Presently, there is a lack of comprehensive strategies aimed at addressing both of these factors simultaneously to interrupt this detrimental cycle. Herein, an immunomodulatory hydrogel (PHG2) is developed for reshaping the hostile DFU microenvironment. The engineered PHG2 not only removes excess internally-produced ROS but also generates O 2 , with its efficiency further boosted by local hyperthermia (42.5 °C) activated by near-infrared light. Through both in vitro and in vivo studies, along with transcriptomic assessment, it is confirmed that PHG2 disrupts the detrimental feedback loop between ROS and inflammation while also lowering the M1/M2 macrophage ratio. Such discoveries contribute to a significant enhancement in the healing process of injuries that undergo a gradual increase in movement, covering wounds from the back, mouth, to the foot. Ultimately, this method provides an easy, safe, and highly effective solution for treating DFUs.
研究领域:
生物医学工程
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组织工程
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伤口愈合
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免疫学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Cleaner Production
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2021
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IF 9.297
Yafei Zhang,Hui Liu,Keyong Tang,Jie Liu,Xiumin Li
Large amounts of water and leather chemicals such as sodium sulfide and calcium hydroxide are used in conventional leather production, resulting in huge amount of wastewater and serious environmental pollution . Enzyme is eco-benign, and an ideal alternative to conventional chemicals attributed to its excellent characteristics and high efficiency. In this work, enzymes with different ions are used in beamhouse to remove the interfibrillar substance and open collagen fiber bundles. Analysis of the opened collagen fibers shows that the enzyme with both hydrogen phosphate and magnesium ions have the best effect in opening collagen fiber bundles. Results of wastewater analysis and the staining of hematoxylin-eosin (H&E) and Verhoeff’s Van Gieson (EVG) indicated the excellent removal of interfibrillar substance by all ion-assisted trials, suggesting an improved removal efficiency. The mechanical properties and shrinkage temperature of the leathers are similar to those of the conventional leathers. Since both deliming and bating are no longer required, a large amount of water can be saved, the leather making time can be shortened, and the cost of wastewater treatment can be reduced. Ion-assisted enzyme method is more efficient and environmentally friendly than the conventional one with sodium sulfide. This work presents a promising path for the cleaner leather making.
研究领域:
化学
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环境科学
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材料科学
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生物技术
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2022
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IF 10.383
Zehua Gao,Yuanman Yu,Kai Dai,Tingting Zhang,Luli Ji,Xuanlin Wang,Jing Wang,Changsheng Liu
Timely restoration of blood supply following ischemia is critical to rescue damaged tissue. However, clinical efficacy is hampered by the inflammatory response after ischemia. Whether inflammation fine tunes the angiogenesis and the function of blood vessels via the heterogeneity of neutrophils remain poorly understood. Herein, the objective of this work is to incorporate the growth factors secreted by neutrophils into a porous gelatin methacrylate (GelMA) hydrogel, which subsequently is used as a novel regenerative scaffold with defined architecture for ischemia. We demonstrate that anti-inflammatory neutrophils (N2-polarized neutrophils) play an important role in promoting the migration of human umbilical vein endothelial cells (HUVECs) and formation of capillary-like networks in vitro. More importantly, vascular anastomosis can be achieved by modulating the neutrophils to N2 phenotype. In addition, N2-polarized composite hydrogel scaffolds can regulate inflammation, maintain the survival of exogenous cells, and promote angiogenesis in vivo. Notably, the composite hydrogel scaffolds promote neovascularization during exogenous introduction of endothelial cells by anastomosis. Taken together, this study highlights N2-polarized neutrophils composite hydrogels can achieve vascularization rapidly by regulating inflammation and promoting vascular anastomosis. This work lays the foundation for research into the treatment of ischemia and may inspire further research into novel treatment options.
研究领域:
生物医学工程
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组织工程
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再生医学
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炎症生物学
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血管生物学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
·
IF 13.2
Xin Rao,Yujing Niu,Qiantao Zhang,Xingcan Chen,Fangmei Zhou,Mingyuan Zhou,Yuchi Chen,Yingzhi Shen,Jie Yu,Bingqi Zhu,Zhishan Ding
Diabetic foot ulcers pose a significant clinical challenge due to dysregulated immune responses, neuropathic complications, and persistent infections that synergistically disrupt physiological tissue regeneration mechanisms. While immune activation is essential for orchestrating wound repair, excessive inflammation often exacerbates tissue damage in chronic diabetic wounds. To address these multifactorial issues, we designed a dual-crosslinked hydrogel platform integrating alginate, Bletilla striata polysaccharides (BSP), and gelatin to encapsulate tannic acid/Fe 3+ (TA/Fe 3+ ) composite nanoparticles with synergistic photothermal antibacterial treatment function. In vitro studies demonstrated that the dual-crosslinked hydrogel modulated immune microenvironment through effective scavenging of pathological reactive oxygen species (ROS) and significant downregulation of pro-inflammatory cytokine expression and promoting fibroblast migration. In addition, TA/Fe 3+ endowed the hydrogel with antibacterial activity under near-infrared (NIR) irradiation. The macrophage phenotype study revealed that the hydrogel promoted anti-inflammatory phenotype reprogramming of bone marrow-derived macrophages (BMDMs) under lipopolysaccharide (LPS) stimulation, which may be achieved by down-regulating the nuclear expression of pyruvate kinase M2 (PKM2). In the in vivo evaluation of the diabetic mouse model, the ability of the hydrogel to accelerate wound closure was verified, and the neovascularization at the lesion site was strongly stimulated. Through the temporal and spatial control of the healing process, the hydrogel has become an integrated treatment platform for chronic infection wound management, showing potential clinical application value.
研究领域:
生物材料
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免疫治疗
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伤口愈合
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纳米医学
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组织工程
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Advanced Healthcare Materials
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2024
·
IF 10
Zihao Wang,Mengyu Li,Jia Chen,Shengmin Zhang,Bin Wang,Jianglin Wang
Diabetic wound exhibits the complex characteristics involving continuous oxidative stress and excessive expression of pro-inflammatory cytokines to cause a long-term inflammatory microenvironment. The repair healing of chronic diabetic wounding is tremendously hindered due to persistent inflammatory reaction. To address the aforementioned issues, here, a dual-functional hydrogel is designed, consisting of N1-(4-boronobenzyl)-N3-(4-boronophenyl)-N1, N1, N3, N3-tetramethylpropane-1, 3-diaminium (TSPBA) modified polyvinyl alcohol (PVA) and methacrylamide carboxymethyl chitosan (CMCSMA) can not only electrostatically adsorb proinflammatory cytokines of IL1-β and TNF-α, but can also chemically scavenge the excessive reactive oxygen species (ROS) in situ. Both in vitro and in vivo evaluations verify that the negatively charged and ROS-responsive hydrogel (NCRH) can effectively modulate the chronic inflammatory microenvironment of diabetic wounds and significantly enhance wound remodeling. More importantly, the well-designed NCRH shows a superior skin recovery in comparison with the commercial competitor product of wound dressing. Consequently, the current work highlights the need for new strategies to expedite the healing process of diabetic wounds and offers a wound dressing material with immunomodulation.
研究领域:
生物材料
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伤口愈合
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糖尿病
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免疫学
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材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）