SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2020
·
IF 3.232
Angxin Tong,Xiaojun Tang,Feng Zhang,Bin Wang
In this study, we mainly focused on predictable regularities of the red shift of ultraviolet spectra for β-phenylethylamine (PEA), NaCl and NaOH in aqueous solution. The absorption peaks of the UV spectra near 191 nm of NaCl, NaOH and PEA in aqueous solution moved in the direction of a red shift while the molar absorption coefficient at the peak increased regularly with the increasing solution concentration. These shifts were obtained for solutions with concentrations ranging from 3.68 to 1000 mmol/L for NaCl, from 0.762 to 2000 mmol/L for NaOH, and from 0.0515 to 8.91 mmol/L for PEA. The plots of the logarithm of the solution concentration for NaCl and PEA versus the absorbance at 191 nm and at the peak were linear, and the plots of the logarithm of the solution concentration for NaCl and PEA versus the wavelength at the peak (shifted from 191 nm) were also linear. In addition, the plots of the logarithm of the solution concentration for NaOH that ranged from 0.762 to 1.96 mmol/L versus the absorbance at 191 nm and at the peak were linear as well as the plots of the logarithm of the solution concentration for NaOH that ranged from 1.96 to 2000 mmol/L versus the wavelength at the peak. The slopes of the absorbance at 191 nm of PEA, NaCl and NaOH were somewhat similar to the absorbance at the peak separately, whereas the slopes of the wavelengths at the peak were different from them. Finally, in order to obtain the predictable regularity of the red shift of the UV spectrum for the mixture, 22 ternary mixtures were prepared. The results indicate that the inhibiting effect of hydroxide ions (OH-) caused the wavelength near 206 nm to remain unchanged when the solution concentration of NaOH in the mixture was more than 0.762 mmol/L.
研究领域:
化学
·
光谱学
·
分析化学
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
·
IF 5.7
Qilin Yang,Yitao Bai,Shuangping Liu,Xiao Han,Tiantian Liu,Dongna Ma,Jian Mao
Elevated levels of biogenic amines (BAs) in fermented food can have negative effects on both the flavor and health. Mining enzymes that degrade BAs is an effective strategy for controlling their content. The study screened a strain of Lactobacillus hilgardii 1614 from fermented food system that can degrade BAs. The multiple copper oxidase genes LHMCO1614 were successfully mined after the whole genome protein sequences of homologous strains were clustered and followed by homology modeling. The enzyme molecules can interact with BAs to stabilize composite structures for catalytic degradation, as shown by molecular docking results. Ingeniously, the kinetic data showed that purified LHMCO1614 was less sensitive to the substrate inhibition of tyramine and phenylethylamine. The degradation rates of tyramine and phenylethylamine in huangjiu (18% vol) after adding LHMCO1614 were 41.35 and 40.21%, respectively. Furthermore, LHMCO1614 demonstrated universality in degrading tyramine and phenylethylamine present in other fermented foods as well. HS-SPME-GC-MS analysis revealed that, except for aldehydes, the addition of enzyme treatment did not significantly alter the levels of major flavor compounds in enzymatically treated fermented foods (p > 0.05). This study presents an enzymatic approach for regulating tyramine and phenylethylamine levels in fermented foods with potential applications both targeted and universal.
研究领域:
微生物学
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食品安全
·
酶学
✓ 已验证
DOI
PubMed
高影响因子
ACS Omega
·
2025
·
IF 4.3
Brian Zhao,Chenghao Wang,Jia Huang,Junyao Zhang
Developing covert, convenient, rapid, and cost-effective detection methods for trace amounts of addictive drugs poses a challenging task. Herein, wood-derived ionic conductive cellulose (WICC) is presented as a sensitive material, where active metal cations serve as charge carriers and effective adsorption/binding sites for a typical analog of the addictive drug N-methylphenethylamine (MPEA). The addition of Cu2+ ions improves the sensing performance of WICC, and the simple drop-coating process will facilitate the fabrication of the device array and the integration with flexible substrates. Taking advantage of WICC with excellent ion conductivity, high transparency, and mechanical flexibility, transparent and flexible sensors based on WICC are demonstrated, enabling real-time detection of MPEA. Notably, the high transparency makes WICC particularly suitable for covert detection. More significantly, the WICC sensors exhibit outstanding selectivity, facilitating an ultralow theoretical detection limit (∼12 nL). This work provides a promising pathway toward the next-stage construction of invisible chemical sensors for addictive drug detection.
研究领域:
材料科学
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分析化学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
Advanced Materials Interfaces
·
2020
·Vol. 7
·期 14
·2000197
·
IF 4.948
Nuo Lei,Lu Pan,Tao Ye,Shuang Chen,Xi Wang
The recent studies widely believe that the stability of (PEA) 2 PbI 4 /MAPbI 3 perovskite solar cells (PSCs) can be progressively increased with the addition of phenethylammonium ion (PEA + ). Herein, it is reported on the stability variations after the addition of PEA + into the MAPbI 3 film and it is demonstrated that excess PEA + has negative effect on the stability of (PEA) 2 PbI 4 /MAPbI 3 perovskite film. X-ray photoelectron spectroscopy, nuclear magnetic resonance, and X-ray absorption fine structure spectroscopy are utilized to testify that the excess PEA + damages the MAPbI 3 crystal structure and generates defects due to the strong coordination between NH 3 + from PEA + and I − from [PbI 6 ] 4− . This work reveals that the stability of (PEA) 2 PbI 4 /MAPbI 3 perovskite films is not proportional to the addition of PEA + , which is of interest for the developing of stable 2D/3D PSCs.
研究领域:
材料科学
·
化学
✓ 已验证
DOI
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 20
·3691
·
IF 5.719
Lin Wang,Hang Liu,Xinsong Li,Chen Yao
In this research, we constructed a novel engineered tripeptide modified with lipoic acid (LA-RWR), followed by crosslinking of lipoic acid to form nanoparticles (c-LA-RWR). LA-RWR was also modified with phenethylamine (PEA) on the C-terminus to achieve better antibacterial activities. The as-prepared c-LA-RWR and LA-RWR-PEA were effective againstE.coli,S.aureus,C.albicans, and methicillin-resistantStaphylococcus aureus, with minimum inhibitory concentration values ranging from 2 to 16 µg/mL, which greatly improved the performance of LA-RWR. Similar antibacterial activities were demonstrated in anti-biofilm activity; there was no matter on the biofilm that was already established or forming. Moreover, c-LA-RWR/LA-RWR-PEA remarkably induced cytoplasmic membrane depolarization and outer membrane permeabilization, resulting in varying degrees of damage to the bacterial morphology, which were consistent with the results obtained via electron microscopy. Thus, our results show that c-LA-RWR/LA-RWR-PEA exhibited excellent efficacy against a variety of microorganisms with good biosafety, providing new strategies by which to improve the performance of antimicrobial peptides.Keywords:antimicrobial peptides;lipoic acid;biofilm;crosslink;nanoparticles;phenethylamine
研究领域:
药学
·
微生物学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Keke Li,Linxin Wang,Jinming Chen,Mingzhu Yan,Yanyan Fu,Qingguo He,Jiangong Cheng
Organic thin-film fluorescent sensors for vapor with high sensitivity, rapid response, and no pollution to analytes have received widespread attention. However, the development of vapor sensors is very slow. The difficulty lies in most fluorescent materials cannot luminesce in solid state because of ACQ (aggregate concentration quenching) effect. Previous works have usually focused on the design and synthesis of new materials to avoid ACQ effect. Whereas, if existing ACQ materials can be utilized, it will greatly expand the selection range of fluorescent materials used in vapor sensors. In this study, a high-performance vapor sensor utilizing ACQ fluorescent material was successfully prepared based on doping/breath figure method. Firstly, the fluorescence emission of ACQ molecule in solid state was realized by doping with polymer. Then porous sensing film was fabricated via breath figure method (BFs) with large surface-to-volume ratio. Finally, the vapor sensing of ACQ molecule was realized. Herein, the molecule BOR−CHO was selected as ACQ probe doping with polystyrene to get good solid-state luminescence. Then high-quality porous sensing film was obtained by optimizing the BFs parameters. Such a film showed a quick fluorescence quenching response to MPEA (simulant of methamphetamine) gas within 20 s with a detection limit of 1.58 ppm. Our results identify a simple strategy to get enhanced optical intensity of BOR−CHO and achieve superior sensing performance towards MPEA. Most importantly, these findings provide a low-cost method for the facile realization of high surface-to-volume ratio fluorescent sensors for vapor analytes via using ACQ materials, with great flexibility and expandability.
研究领域:
化学传感器
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材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2023
·Vol. 28
·期 3
·922
·
IF 4.6
Pengcheng Li,Jingjing Zhu,Hongyu Zhang,Lan Wang,Shulin Wang,Mengting Zhang,Jianping Wu,Lirong Yang,Gang Xu
Chiral amines are essential components for many pharmaceuticals and agrochemicals. However, the difficulty in obtaining enantiomerically pure amines limits their application. In this study, hollow amorphous ZIF-90 (HamZIF-90) materials were prepared by template engraving, and chemical–enzyme coupling catalysts (HamZIF-90@Pd@CALB) were constructed for the chiral resolution of 1-phenylethylamine. Different from conventional materials, HamZIF-90 had tunable hollow structures by altering its central node zinc ion concentrations, and the embedded hydrogel template gave it more pore structures, which facilitated the loading of enzyme molecules and Pd nanoparticles (NPs). The establishment of the coupling catalysts shortened the mass transfer distance of the reactant molecules between the metal nanoparticles and the enzyme catalyst in the dynamic kinetic resolution (DKR) reaction, resulting in 98% conversion of 1-phenylethylamine and 93% selectivity of Sel.R-amide. The proposal of this idea provided a good idea for future tailor-made MOFs loaded with chemical and enzyme coupled catalyst.Keywords:hollow amorphous;HamZIF-90@Pd@CALB;DKR;1-phenylethylamine
研究领域:
化学
·
生物催化
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small
·
2020
·Vol. 16
·期 50
·2005246
·
IF 11.459
Qiufeng Ye,Fei Ma,Yang Zhao,Shiqi Yu,Zema Chu,Pingqi Gao,Xingwang Zhang,Jingbi You
Cesium lead iodide (CsPbI 3 ) perovskite has gained great attention due to its potential thermal stability and appropriate bandgap ( ≈ 1.73 eV) for tandem cells. However, the moisture-induced thermodynamically unstable phase and large open-circuit voltage ( V OC ) deficit and also the low efficiency seriously limit its further development. Herein, long chain phenylethylammonium (PEA) is utilized into CsPbI 3 perovskite to stabilize the orthorhombic black perovskite phase (γ-CsPbI 3 ) under ambient condition. Furthermore, the moderate lead acetate (Pb(OAc) 2 ) is controlled to combine with phenylethylammonium iodide to form the 2D perovskite, which can dramatically suppress the charge recombination in CsPbI 3 . Unprecedentedly, the resulted CsPbI 3 solar cells achieve a 17% power conversion efficiency with a record V OC of 1.33 V, the V OC deficit is only 0.38 V, which is close to those in organic-inorganic perovskite solar cells (PSCs). Meanwhile, the PEA modified device maintains 94% of its initial efficiency after exceeding 2000 h of storage in the low-humidity controlled environment without encapsulation.
研究领域:
材料科学
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光伏技术
·
能源研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Silei Wang,Mengyao Li,Chunyu Song,Chenglong Zheng,Jitao Li,Zhongyang Li,Yating Zhang,Jianquan Yao
A tailored interface located at the buried perovskite heterojunction is often employed to ameliorate the performance and reliability of n - i - p plane structure perovskite photovoltaic devices. Refinements of interfacial properties such as energy band alignment, surface defects passivation and lattice matching ensure efficient extraction and transport of photogenerated charge carriers. Here, we demonstrated that the phenethylammonium iodide (PEAI) is employed to regulate the tin oxide (SnO 2 )/perovskite interface. Incorporating PEAI into SnO 2 can passivate crystallographic defects and realign the energy band, thereby contributing to high electronic mobility of electron selective layers (ESLs) and electron extraction rate optimization at the buried perovskite heterojunction interface. Additionally, the charge carrier non-radiative recombination of perovskites based on PEAI- modified SnO 2 is also suppressed due to the augmentation of perovskite crystallinity induced by the hydrophobicity of the ESL film. Meanwhile, theoretical calculations verified the intrinsic mechanism that the formed N-O bond interaction facilitates charge transfer at the SnO 2 /perovskite interface. Consequently, metal halide perovskite photodetector (PPD) based on PEAI-modified SnO 2 achieved a decent specific detectivity of 2.57 × 10 12 Jones (1 Jones = 1 cm Hz 1/2 W −1 ), a responsivity of 0.40 A/W and an extensive linear dynamic range of 161 dB with self-powered mode. The unencapsulated PPD with PEAI-modified SnO 2 ESL maintains over 75% of the initial photoresponse after 30 days in the atmospheric environment.
研究领域:
材料科学
·
光电子学
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2023
·
IF 4.1
Angxin Tong,Xiaojun Tang,Haibin Liu,Honghu Gao,Xiaofei Kou,Qiang Zhang
The aim of this study is to enhance the classification performance of the back-propagation-artificial neural network (BP-ANN) algorithm for NaCl, NaOH, β-phenylethylamine (PEA), and their mixture, as well as to avoid the defects of the artificial bee colony (ABC) algorithm such as prematurity and local optimization. In this paper, a method that combined an improved adaptive artificial bee colony (IAABC) algorithm and BP-ANN algorithm was proposed. This method improved the ABC algorithm by adding an adaptive local search factor and mutation factor; meanwhile, it can enhance the abilities of the global optimization and local search of the ABC algorithm and avoid prematurity. The extracted score vectors of the principal component of the ultraviolet (UV) spectrum were used as the input variable of the BP-ANN algorithm. The IAABC algorithm was used to optimize the weight and threshold of the BP-ANN algorithm, and the iterative algorithm was repeated until the output accuracy was reached. The output variable was the classification results of NaCl, NaOH, PEA, and the mixture. Meanwhile, the proposed IAABC-BP-ANN algorithm was compared with discriminant analysis (DA), sigmaid-support vector machine (SVM), radial basis function-SVM (RBF-SVM), BP-ANN, and ABC-BP-ANN. Then, the above algorithms were used to classify NaCl, NaOH, PEA, and the mixture, respectively. In the experiment, four indicators, accuracy, recall, precision, and F-score, were used as the evaluation criteria. In addition, the regression equation parameters of the mixture for the testing set were obtained by BP-ANN, ABC-BP-ANN, and IAABC-BP-ANN models. All of the results showed that IAABC-BP-ANN exhibits better performance than other algorithms. Therefore, IAABC-BP-ANN combined with UV spectroscopy is a potential identification tool for the detection of NaCl, NaOH, PEA, and the mixture.
研究领域:
化学信息学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Zhijia Liao,Ninghao Chu,Zhenyu Yuan,Renze Zhang,Hongmin Zhu,Yanbai Shen,Fanli Meng
The novel copper hydroxyfluoride-copper oxide (CHFCO)/zinc hydroxyfluoride-zinc oxide (ZHFZO) nanomaterials were prepared by hydrothermal method and exhibited superior sensing performance for methamphetamine analogue-phenethylamine. The sensing characteristics of calcined ZHFZO rods, CHFCO flakes, and four composite nanomaterial ratios were examined. The experimental results demonstrated that the CHFCO/ZHFZO-2 sensor exhibited improved sensing performance for phenethylamine, with the optimum working temperature reduced to 200 ℃. The responses of the ZHFZO and CHFCO sensors to 10 ppm phenylethylamine were 1.9 and 3.5, respectively, while the response of the CHFCO/ZHFZO-2 sensor was enhanced to 5. With a response time (T res ) and recovery time (T rec ) of 30 s for 10 ppm phenylethylamine, the sensor enables rapid detection. It has great selectivity and reproducibility for phenylethylamine and can detect concentrations as low as 125 ppb, demonstrating its potential for quantitative detection at the parts per billion (ppb) level. The prepared composites possessed unique nanostructures and large specific surface areas . The substitution of fluoride ions produces a large electronegativity and the physical adsorption of polar hydroxyl bonds combine to enhance the sensitization of phenylethylamine gas. The findings presented in this study underscore the promising potential of the synthesized nanomaterials for highly sensitive and selective detection of phenylethylamine.
研究领域:
材料科学
·
化学传感器
·
药物检测
✓ 已验证
产品关联
DOI
高影响因子
Catalysts
·
2022
·Vol. 12
·期 10
·1265
·
IF 4.501
Lihua Du,Lingyan Zheng,Yue Pan,Zhikai Sheng,Shiyi Zhang,Hang Lin,Aoying Zhang,Hanjia Xie,Xiping Luo
While a few derivatives of cinnamamides exhibited anti-inflammatory and/ or analgesic activity, in this study, we developed a highly efficient method for the synthesis of cinnamamides from methyl cinnamates and phenylethylamines catalyzed by Lipozyme®TL IM in continuous-flow microreactors. The reaction parameters and broad substrate range of the new method was studied. Maximum conversion (91.3%) was obtained under the optimal condition of substrate molar ratio of 1:2 (methyl 4-chlorocinnamate: phenylethylamine) at 45°Cfor about 40 min. The remarkable features of this work include short residence time, mild reaction conditions, easy control of the reaction process, and that the catalyst can be recycled or reused, which provide a rapid and economical strategy for the synthesis and design of cinnamamide derivatives for further research on drug activity.
研究领域:
有机化学
·
药物化学
·
生物催化
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）