JOURNAL OF SURFACTANTS AND DETERGENTS
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2012
·Vol. 16
·期 2
·265-269
·
IF 1.545
Yinghong Liu,Huijuan Wu,Weixing Ma
A direct, extraction-free spectrophotometric method was developed for the determination of benzalkonium bromide (BAK). The method is based on the formation of mixed dye–surfactant aggregates between alizarin green (AG) and BAK in alkaline medium by measuring the decrease in absorbance of AG at 460 and 700 nm. Beer's law was obeyed in the concentration range 3–40 μg mL −1 with good precision and accuracy. The limits of detection were 0.4 μg mL −1 at 460 nm and 0.3 μg mL −1 at 700 nm, which reduced to 0.2 μg mL −1 by combining the absorbance at the two wavelengths. The proposed method was successfully applied to the determination of BAK in disinfectant solution and eye drops. The analytical results of the real samples were in good agreement with those of an HPLC method.
研究领域:
分析化学
·
药学
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DOI
高影响因子
Foodborne Pathogens and Disease
·
2024
·
IF 1.9
Ji Zeng,Rong Fu,Jiahao Ji,Tong Xing,Dongping Hou,Zefeng Li,Zepeng Zhao,Shaoting Li,Hongmei Zhang
Salmonella enterica is a common foodborne pathogen that poses significant safety risks across the world. And benzalkonium bromide (BK) is widely used as a disinfectant to sterilize the food processing equipment. It has been reported that sub-lethal concentration of disinfectants induced not only the homologous resistance but also cross-resistances. This work analyzed the induced resistances of Salmonella Enteritidis by short-term adaptation (STA) and long-term adaptation (LTA) to BK. We have demonstrated that inefficient sterilization exposes Salmonella Enteritidis to sub-lethal concentrations of BK, and adapts bacteria to a higher minimum inhibitory concentration and minimum bactericidal concentration. In addition, STA, but not LTA, to BK induced heterogeneous resistance to sodium hypochlorite, and cross-resistance to freezing, desiccation, and heating, which may be caused by the membrane composition change of Salmonella Enteritidis. This work could be useful to the optimization of cleaning protocol.
研究领域:
食品安全
·
微生物学
·
消毒剂研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Shuang Lin,Changsheng Qu,Dongyao Xu
The reutilization of industrial steel slag (SS) as an adsorbent for petroleum wastewater treatment was achieved through acid activation and subsequent surface modification with quaternary ammonium surfactants to yield organo-functionalized silica-rich materials (organo-SRSs). Acid activation exposed a highly hydroxylated SiO₂ matrix, enabling effective organic grafting and imparting enhanced hydrophobicity. Among the prepared materials, benzalkonium chloride functionalized silica-rich material (BC-SRS) exhibited superior performance, achieving a maximum naphthalene (NA) adsorption capacity of 462.9 mg/g due to synergistic π–π stacking, hydrophobic interactions, and weak electrostatic forces. Adsorption followed pseudo-second-order kinetics and Freundlich isotherms, with thermodynamic analysis indicating spontaneous and endothermic behavior for BC-SRS. The material demonstrated excellent reusability and selectivity under complex water chemistries. This work presents a sustainable strategy for converting industrial waste into high-efficiency adsorbents, advancing green remediation and circular resource utilization.
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2023
·
IF 5.8
Chuanhui Teng,Wei Lv,Yuqin Chen,Linfeng Liu,Jiaqing Yin,Shengnan Li,Zhiyi Min,Qi Zhang,Weichong He,Kunfang Ma,Xinrui Li,Xiang Cao,Hongliang Xin
Since ischemic stroke occurs by a combination of multiple mechanisms, therapies that modulate multiple mechanisms are required for its treatment. The combination of edaravone (EDA) and borneol can significantly ameliorate the symptoms of neurological deficits in cerebral ischemia–reperfusion model in rats. In this study, the solubility of borneol and edaravone was improved by hydroxypropyl-β-cyclodextrin and PEG 400 . Furthermore, a nasal temperature-sensitive hydrogel containing both edaravone and borneol inclusion complex (EDA-BP TSG S ) was developed to overcome the obstacles of ischemic stroke treatment including the obstruction of the blood–brain barrier (BBB) and the unavailability and untimely of intravenous injection. The effectiveness of the thermosensitive hydrogel was investigated in transient middle cerebral artery occlusion/reperfusion model rats (MCAO/R). The results showed that EDA-BP TSG S could significantly alleviate the symptoms of neurological deficits and decrease the cerebral infarct area and the degree of brain damage. In summary, nasal EDA-BP TSG S is a secure and effective brain-targeting formulation that may provide a viable option for the clinical prophylaxis and treatment of ischemic stroke.
研究领域:
药剂学
·
神经科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2023
·
IF 5.4
Zhiqiang Han,Busheng Zhang,Jieyao Li,Haoqi Guo,Liying Song,Woon-Ming Lau
The surface of a glass plate was molecularly engineered to become antimicrobial by coating it with a self-assembled layer of (3-aminopropyl) trimethoxysilane (APTMS) and then with an overlayer of antimicrobial benzyldodecyldimethylammonium bromide (BAB). Hyperthermal H 2 molecules with a kinetic energy of about 15 eV were used as “bullets” to collide with BAB and APTMS to selectively cleave the C H bonds in them. Subsequent recombination of the carbon radicals thus formed lead to the crosslinking and fixation of BAB to APTMS which is itself strongly bonded to the glass surface via silanization. Molecular dynamics simulations were conducted to validate this peculiar hyperthermal hydrogen induced cross-linking (HHIC) mechanism, and hyperthermal hydrogen molecules with a high flux density over 1 × 10 15 H 2 /cm 2 s for completing the HHIC process in 10 s in reaction-time were experimentally generated with a specifically designed instrument. The glass silanization with APTMS and the fixation of BAB molecules were assessed and confirmed by water contact angle (WCA) measurements, X-ray photoelectron spectroscopy (XPS), as well as atomic force microscopy (AFM). The antimicrobial activity against staphylococcus aureus was confirmed with the standard ISO/DIS 22196 test-method.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）