RSC Advances
·
2015
·Vol. 5
·期 86
·70178-70185
·
IF 3.84
Mingfang Ma,Jinge Gu,Minmin Yang,Zhaolou Li,Zhuoqun Lu,Yimeng Zhang,Pengyao Xing,Shangyang Li,Xiaoxiao Chu,Yajie Wang,Qi Li,Minyan Lin,Aiyou Hao
Sodium benzoate is an important and widely used food additive, however, its self-assembly properties in diverse solvents have been rarely studied. Here, we report different self-assembled aggregates, including sodium benzoate vesicles and sodium benzoate gel, in different solvent environments. Sodium benzoate vesicles and gel were identified by Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and Dynamic Light Scattering (DLS). Ultraviolet-visible (UV-vis) spectroscopy, Fourier Transform Infrared (FT-IR) spectroscopy, Thermal Gravity Analysis (TGA), Differential Scanning Calorimetry (DSC) and Small-Angle X-ray Scattering (SAXS) were further employed to study the formation mechanism of the sodium benzoate gel. A possible gel formation mechanism was proposed. Furthermore, sodium benzoate gel has multiple stimulus responsiveness, the addition of hydrochloric acid and metal ions can all cause disaggregation of sodium benzoate gel. Finally, sodium benzoate aggregates were found in calf serum.
研究领域:
材料科学
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食品科学
·
化学
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DOI
高影响因子
Collagen and Leather
·
2024
·Vol. 6
·期 1
·1-12
·
IF 0
Zhang Chi,Zhou Ji-bo,Sun Nan,Liao Xue-pin,Shi Bi
Melamine resin (MR), traditionally synthesized using melamine and formaldehyde, is widely used in the leather industry. However, the emission of free formaldehyde poses a significant challenge for conventional MR. To address the issues of aldehyde in MR, extensive research has been conducted. This paper introduces a novel aldehyde-free MR (LTSL) retanning agent synthesized using cyanuric chloride, l-lysine, and sodium sulfanilate. The chemical structure of LTSL was analyzed via Fourier transform infrared spectroscopy, nuclear magnetic resonance, and X-ray photoelectron spectroscopy. The presence of amino, carboxyl, and sulfonic acid groups in LTSL enhanced its storability and imparted LTSL with an amphoteric character. The isoelectric point of LTSL was optimized to reach 4.37, and LTSL exhibited an appropriate size distribution with an average particle size of 254.17 nm and achieved high absorption rates of 87.77% and 95.84% for retanning and fatliquoring agents, respectively. Consequently, the thickness rate of LTSL reached up to 37%, with no detectable formaldehyde. Notably, LTSL also demonstrated excellent physical and mechanical properties, primarily attributed to the coordination and electrostatic interactions between the chrome-tanned collagen fiber and amino/carboxyl groups in LTSL. This research presents an innovative approach for developing an aldehyde-free MR retanning agent, significantly contributing to the sustainable development of leather manufacturing. Graphical Abstract
研究领域:
材料科学
·
皮革工业
·
化学合成
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DOI
FOOD CHEMISTRY
·
2024
·
IF 8.5
Ze Xu,Li Jin,Bowen Yang,Wenwen Wang,Yukun Yang,Guanjun Wang,Jizhou Wu,Dandan Sun,Jie Ma
A molecularly imprinted polymer (MIP) based microfiber differential demodulation sensing system for sodium benzoate (SB) concentration detection is proposed. The specific binding of MIP on the surface of microfibers with SB can lead to changes in local refractive index (RI). RI change induces a drift in the interference wavelength, which can be monitored by the power difference between two fiber Bragg gratings (FBGs). The sensing system can detect SB in the concentration range of 0.1–50 μg/ml, and interference wavelength and FBG power difference sensitivities are 0.55 nm/(μg/ml) and 2.64 dB/(μg/ml) in the low concentration range of 0.1–1 μg/ml, respectively, with a limit of detection (LOD) of 0.1 μg/ml. This microfiber differential demodulation sensing system is not only simple to fabricate, but also simplifies the demodulation equipment to reduce the cost, which providing a simple, reliable and low-cost technique for the quantitative detection of SB concentration in beverages and flavoured foods.
研究领域:
食品科学
·
光学传感
·
材料科学
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产品关联
DOI
PubMed
高影响因子
Biosensors-Basel
·
2022
·Vol. 12
·期 12
·1084
·
IF 5.743
Tao Tian,Wei-Yi Zhang,Hang-Yu Zhou,Li-Jing Peng,Xi Zhou,Hao Zhang,Feng-Qing Yang
In this study, the personal glucose meter (PGM) was first used as a fast and user-friendly meter for analyzing catechol (CA) based on the reduction of the mediator K3[Fe(CN)6] to K4[Fe(CN)6] in the glucose test strip. Then, an easy, low-cost, and convenient PGM-based method for detecting tyrosinase (TYR) activity and sodium benzoate (SBA) was developed on the basis of the TYR-catalyzed reaction. In this method, CA is oxidized to formo-benzoquinone by TYR, thereby reducing the residual amount of CA and the PGM readout. On the other hand, SBA can inhibit the oxidation of CA catalyzed by TYR and increase the residual amount of CA after the enzymatic reaction. Therefore, the activity of TYR is proportional to the difference in the PGM readout of CA, and the concentration of SBA is positively correlated with the residual amount of CA. After the relevant experimental conditions were systematically optimized, the proposed PGM-based method for the detection of TYR and SBA was successfully validated. The liner ranges are 1.0–103.3 U/mL and 6.25–1000 ppm, and the quantification limits are 1.0 U/mL and 6.25 ppm for TYR and SBA, respectively. Moreover, the spiked recovery tests in normal human serum and carbonate beverages (i.e., Cola, Sprite, and Fanta) were performed, and the recoveries (91.6–106.8%) further confirm the applicability of the PGM-based method in real sample analysis.Keywords:tyrosinase;sodium benzoate;personal glucose meter;enzyme sensor;carbonate beverages sample
研究领域:
分析化学
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生物化学
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食品科学
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产品关联
DOI
PubMed
高影响因子
Frontiers in Microbiology
·
2022
·
IF 6.064
Dong Yuling,Ding Zhongfeng,Song Linxia,Zhang Desheng,Xie Changjian,Zhang Shujing,Feng Ling,Liu Hongliang,Pang Qiuxiang
Sodium benzoate (SB), the sodium salt of benzoic acid, is widely used as a preservative in foods and drinks. The toxicity of SB to the human body attracted people’s attention due to the excessive use of preservatives and the increased consumption of processed and fast foods in modern society. The SB can inhibit the growth of bacteria, fungi, and yeast. However, less is known of the effect of SB on host commensal microbial community compositions and their functions. In this study, we investigated the effect of SB on the growth and development of Drosophila melanogaster larvae and whether SB affects the commensal microbial compositions and functions. We also attempted to clarify the interaction between SB, commensal microbiota and host development by detecting the response of commensal microbiota after the intervention. The results show that SB significantly retarded the development of D. melanogaster larvae, shortened the life span, and changed the commensal microbial community. In addition, SB changed the transcription level of endocrine coding genes such as ERR and DmJHAMT. These results indicate that the slow down in D. melanogaster larvae developmental timing and shortened life span of adult flies caused by SB intake may result from the changes in endocrine hormone levels and commensal microbiota. This study provided experimental data that indicate SB could affect host growth and development of D. melanogaster through altering endocrine hormone levels and commensal microbial composition.
研究领域:
毒理学
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微生物学
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发育生物学
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分子生物学
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DOI
PubMed
高影响因子
TALANTA
·
2019
·
IF 4.916
Linke Xue,Linke Chen,Jing Dong,Lemei Cai,Yiru Wang,Xi Chen
Medicine safety has become a large concern and prompts an urgent need to develop a rapid, simple and sensitive analytical method, which can monitor excessive preservatives in medicine. In this work, dispersive liquid-liquid microextraction (DLLME) was combined with surface enhanced Raman scattering (SERS) for a quick analysis of a kind of preservatives, sodium benzoate , in ibuprofen oral solution. The experimental parameters affecting DLLME were systematically investigated. Under the optimal conditions, the whole procedure, including DLLME and the SERS analysis, could be carried out within 10 min. A good linearity between the concentration of sodium benzoate ranging from 10 to 500 mg L −1 and the SERS signal intensity could be obtained, and the correlation coefficient (R 2 ) 0.9986. The method detection limit was 0.56 mg L −1 . The relative standard deviation was less than 6.33% for ten replicates at the same sample concentrations. The analytical results prove that the method is suitable for rapid determination of sodium benzoate in ibuprofen oral samples.
研究领域:
分析化学
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药物分析
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产品关联
DOI
PubMed
高影响因子
Science China-Earth Sciences
·
2016
·Vol. 60
·期 2
·391-396
·
IF 1.655
Li Jing,Sun Lei,Yu ZhiMing,Song XiuXian
Prevention of annual “green tides” caused by blooms of the green macroalga Ulva prolifera , which have occurred in the Yellow Sea since 2007, has received much attention. Increasing evidence indicates that micro-propagules on the rafts used for Porphyra yezoensis aquaculture along the coastline of Jiangsu Province in China, were the primary source of these green tides. In this study, we investigated the effectiveness of a silicone antifouling coating for preventing the adhesion and germination of U. prolifera micro-propagules on bamboo and nylon ropes, which have been used in rafts for P. yezoensis aquaculture. Our results demonstrated that a coating of silicone (Sylgard 184) containing 1.0 wt.% sodium benzoate (NaB) could reduce the adhesion rate to <5% and completely inhibited the growth of U. prolifera propagules on the coated surfaces. Coating bamboo and nylon ropes with NaB-incorporated silicone thus proved a potentially effective method for controlling the initial biomass accumulation of U. prolifera .
研究领域:
海洋生物学
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环境科学
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水产养殖
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Chao-Jian Hu,Yi-Qing Lv,Wen-Dong Xian,Jian-Yu Jiao,Zheng-Han Lian,Sha Tan,Meng-Meng Li,Zhen-Hao Luo,Ze-Tao Liu,Ai-Ping Lv,Lan Liu,Mukhtiar Ali,Wei-Qiu Liu,Wen-Jun Li
Biodegradation stands as an eco-friendly and effective approach for organic contaminant remediation. However, research on microorganisms degrading sodium benzoate contaminants in extreme environments remains limited. In this study, we report to display the isolation of a novel hot spring enriched cultures with sodium benzoate (400 mg/L) as the sole carbon source. The results revealed that the phylum Pseudomonadota was the potential sodium benzoate degrader and a novel genus within the family Geminicoccaceae of this phylum. The isolated strain was named Benzoatithermus flavus SYSU G07066 T and was isolated from HNT-2 hot spring samples. Genomic analysis revealed that SYSU G07066 T carried benABC genes and physiological experiments indicated the ability to utilize sodium benzoate as a sole carbon source for growth, which was further confirmed by transcriptomic data with expression of benABC . Phylogenetic analysis suggested that Horizontal Gene Transfer (HGT) plays a significant role in acquiring sodium benzoate degradation capability among prokaryotes, and SYSU G07066 T might have acquired benABC genes through HGT from the family Acetobacteraceae . The discovery of the first microorganism with sodium benzoate degradation function from a hot spring enhances our understanding of the diverse functions within the family Geminicoccaceae . This study unearths the first novel genus capable of efficiently degrading sodium benzoate and its evolution history at high temperatures, holding promising industrial applications, and provides a new perspective for further exploring the application potential of hot spring “microbial dark matter”.
研究领域:
微生物学
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环境科学
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基因组学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
TALANTA
·
2021
·
IF 6.057
Haizhi Zhang,Huanyu Yang,Pei Liu,Xinguang Qin,Gang Liu
A rapid colorimetric method for detecting sodium benzoate in food products was established based on the d -amino acid oxidase (DAAO) and 2D metal organic framework (2D MOF) nanosheets mediated cascade enzyme reactions. Firstly, the synthesized 2D MOF nanosheets served as high efficient nanozyme with outstanding peroxidase-like catalytic activity and catalyzed the color reaction between H 2 O 2 and 3, 3’, 5, 5′- tetramethylbenzidine. Secondly, sodium benzoate as a competitive inhibitor of DAAO, could influence the production of H 2 O 2 in DAAO mediated oxidation reaction. After a combination of those two reactions, this colorimetric quantitative method was constructed and validated for sodium benzoate determination with wide linear range (2.0–200.0 μM), low limit of detection (2.0 μM), high accuracy (recovery rate in 95.80–108.00%) and satisfied selectivity . Lastly, this method was utilized to analyze sodium benzoate concentration in juice, wine and vinegar by naked eyes.
研究领域:
食品科学
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分析化学
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纳米技术
·
酶学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Yanjun Wang,Yuancai Lv,Yifan Liu,Minghua Liu
The electrochemical reduction of nitrate for ammonia production is recognized as a viable method to support a sustainable artificial nitrogen cycle. Extensive research has been focused on enhancing the performance and selectivity of electrocatalysts for NO 3 - RR (nitrate reduction reaction). In this study, we show that modifying the surface oxygen species via thermal treatment and dispersant addition is an effective way to improve the NO 3 - RR performance of Cu 2 O/CF. Using advanced spectroscopic methods, we show that thermal treatment and dispersant addition can greatly boost the generation of oxygen vacancies and hydroxyl groups on the surface of Cu 2 O/CF. Electrocatalytic reaction rate experiment, in-situ FT-IR, DEMS analyses and DFT calculations further suggest that oxygen vacancies on the Cu 2 O/CF surface promote the adsorption and conversion of nitrate and its intermediate, nitrite. Meanwhile, hydroxyl groups promoted the selective hydrogenation of NO to NH 3 . Our findings highlight the essential role of surface oxygen species in NO 3 - RR and provide a foundation for designing advanced electrocatalysts through surface engineering approaches.
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产品关联
DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2025
·
IF 3.6
Mengke Bai,Wenya Lai,Fei Zhou,Hangqing Xie,Jing Xu,Jiadi Lian,Shiqing Xu
Triplet excitons serve as a critical pathway for harvesting energy released during X-ray interactions with heavy elements; however, strategies to enhance their activation efficiency remain limited. Herein, we report a novel organic doping approach to optimize the triplet radioluminescence (RL) of Tb 3+ /Ga 3+ metallacrown (Tb-1) scintillators. By introducing 1,2,4,5-benzenetetracarboxylic acid (PMA) as a ligand dopant, a new scintillation crystal, Tb-1-PMA, is synthesized. Compared to the Tb-1 crystal, Tb-1-PMA exhibits a significant reduction in metal content while maintaining structural integrity. When excited by ultraviolet light or X-rays, Tb-1-PMA crystal emit bright green light, and the photoluminescence quantum yield (PLQY) is increased from 36.8 % to 45.3 %. The RL intensity of Tb-1-PMA surpasses that of Tb-1 by 50 %, achieving a relative light yield of 17,000 photons MeV −1 , accompanied by nearly eliminated afterglow. These enhancements stem from improved energy-level alignment between organic triplet excitons and Tb 3+ in Tb-1-PMA, enabling efficient energy transfer. The RL intensity demonstrates a linear response to X-ray dose rates, with a detection limit of 0.044 μGy s −1 , approximately 123-fold lower than conventional diagnostic doses. This work provides a cost-effective and scalable strategy for designing organic-doped high-performance triplet-emitting scintillators.
研究领域:
材料科学
·
辐射探测
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发光材料
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无机化学
·
核仪器
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2025
·
IF 4
Ziang Yan,Jingyang Zhao,Xuan Lin,Zhengjun Li,Weiqing Zhou,Xiangming Na,Zhiguo Su,Songping Zhang
Imidazolium-based ionic liquids (ILs) as ligand have shown great potentials in biomacromolecule separation by chemically coupling the cationic functional group of the ILs to solid supports. Whether and how the counterions affect the adsorption of biomacromolecule, however remains unclear. In this work, GigaMIm chromatographic media was prepared by coupling an ionizable 1-methylimidazole (MIm) to giga-porous microspheres and paired with four different counterions including Cl − , H 2 PO 4 − , benzoate ion (BZA − ), and 4-hydroxybenzenesulfonate (HBS − ). The types of the counterions on GigaMIm was found to significantly influence the adsorption kinetics and isotherms of yeast RNA and BSA, as well as the chromatographic separation of RNA-BSA mixture. Compared to the media paired with inorganic ions (Cl − and H 2 PO 4 − ), those paired with benzene ring-containing counterions (HBS − and BZA − ) exhibited slightly slower pore diffusion kinetics and lower adsorption capacities for both RNA and BSA, but provided better separation resolution for their mixture. Molecular docking suggested that enhanced hydrogen bonding between MIm⁺/HBS⁻ or MIm⁺/BZA⁻ and biomolecules contributed to improved resolution. The counterion-tuning strategy was further validated by separation of eGFP mRNA from in vitro transcription system. Compared to GigaMIm-Cl, purification using GigaMIm-HBS obtained higher mRNA recovery (38.42% vs. 30.94%) with high mRNA purity and lower T7 polymerase residual (0.16% vs. 0.21%). These findings demonstrate that modulating counterions in ILs-based media may offer a promising strategy for optimizing nucleic acid and protein separation.
研究领域:
生物分离工程
·
分子生物学
·
分析化学
·
药物分析
·
生物材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）