JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2024
·
IF 4
Jia-Rui Xu,Yi Zheng,Tian-Zhen Liu,Bao-Xiang Zhao,Kai-Ming Wang
Hydrogen sulfide (H 2 S) and thiophenol (PhSH) are toxic pollutants that can affect the quality and safety of food and water. It is of importance to detect these analytes. However, developing fluorescent probes that can selectively discriminate H 2 S and PhSH is challenging due to their similar reactivity. In this work, we reported a dual-functional probe N -(4-(benzo[ d ]thiazol-2-yl)phenyl)− 2,4-dinitrobenzenesulfonamide ( NBT ) that could synchronously and selectively respond to H 2 S and PhSH in different solvents. NBT exhibited high selectivity, a low detection limit (82.66 nM for H 2 S, 21.44 nM for PhSH), and a wide linear range (5–70 μM for H 2 S, 5–35 μM for PhSH). Therefore, NBT was successfully applied to detect H 2 S and PhSH in water and beer samples with excellent recovery and precision. This probe provides a simple and effective method for the simultaneous and quantitative detection of H 2 S and PhSH in water and beer samples without the need for sophisticated instruments.
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2012
·
IF 5.856
Zheng Wang,De-Man Han,Wen-Ping Jia,Qi-Zhong Zhou,Wei-Ping Deng
The development of highly sensitive and selective detection techniques for the discrimination of relevant toxic benzenethiols and biologically active aliphatic thiols is of considerable importance in the fields of chemical, biological, and environmental sciences. In this article, we describe a new design of reaction-based fluorescent probe for discrimination of thiophenols over aliphaticthiols through intramolecular charge transfer pathways using N-butyl-4-amino-1,8-naphthalimide as a fluorophore, the strongly electron-withdrawing 2,4-dinitrobenzenesulfonamide group as a recognition unit, and 2,3-dihydroimidazo-[1,2-a] pyridine moiety as a linker. This rational design not only affords finely tunable spectroscopic properties by adding 2,3-dihydroimidazo-[1,2-a] pyridine moiety but also provides the chance to regulate the selectivity and sensitivity of the probe due to the formation of a new type of potentially reversible sulfonamide bond through 4-dimethylaminopyridine-like resonance. The developed probe displayed high off/on signal ratios, good selectivity, and sensitivity with a detection limit of 20 nM and a relative standard deviation of 1.7% for 11 replicate detections of 0.33 μM thiophenol and was successfully applied to the determination of thiophenols in water samples with quantitative recovery (from 94% to 97%) demonstrating its application prospect for thiophenols sensing in environmental and biological sciences.
研究领域:
化学科学
·
环境科学
·
生物科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Guoxing Hu,Xianteng Meng,Chao Zang,Zhi Wang,Wenge Yang,Yonghong Hu
In this study, a NIR fluorescent probe based on ICT principles was developed for the detection of phenylthiophenol. An excellent fluorescent mother nucleus is constructed with tricyano groups, and benzenesulfonate was introduced as a specific recognition site for thiophene, which can be used for rapid detection of thiophenol. The probe has a significant Stokes shift (220 nm). Meanwhile, it had rapid response to thiophene and high specificity. The fluorescence intensity of the probe at 700 nm showed a good linear relationship with thiophene concentration in the range of 0 to 100 μM, and the detection limit was as low as 45 nM. The probe had also been successfully applied to the detection of thiophene in real water samples. MTT assay showed low cytotoxicity and excellent fluorescence imaging in live cells.
研究领域:
分析化学
·
生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF RAMAN SPECTROSCOPY
·
2017
·Vol. 49
·期 3
·520-525
·
IF 2.969
Yun Ling,Wen-Chang Xie,Wei-Li Wang,Meng-Kai Li,Jing Tang,Guo-Kun Liu,Run-Wen Yan,De-Yin Wu
Taking the fingerprint characteristics of Raman spectroscopy, the dimerization of p-nitrothiophenol (PNTP) to 4-nitrophenyl disulfide in air was investigated, which could be accelerated by the external laser illumination. The dimerization was qualitatively confirmed by both mass spectroscopy experimentally and by Raman spectrum simulated calculations theoretically and quantitatively analyzed by Raman spectroscopy in a simple and quick manner. On the basis of the inductively coupled plasma optical mass spectrometry analysis, the dimerization was possibly ignited by the trace metal residues as catalyst in the PNTP. This study clearly shows that it is very important to strictly and preciously control the experimental conditions of Raman measurement and other laser-based spectroscopies to avoid any wrong conclusion during the characterization or identification. Different to the plasmon-induced photochemical reactions, we reported the photochemical reaction of PNTP to 4-nitrophenyl disulfide, which is free of the plasmoic effect from the metal nanostrucutres. On the other hand, the photochemical dimerization reaction may provide a new and important guideline for the formation of thiols to disulfides.
研究领域:
分析化学
·
物理化学
·
光谱学
✓ 已验证
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Yufei Wang,Cui Zhang,Ruiying Yu,Zhe Wu,Yingjie Wang,Wei Wang,Yongchao Lai
Nitrites are ubiquitous in food and pose a serious threat to human health. Therefore, the rapid and accurate determination of nitrite ion concentration in food is a prerequisite for eliminating the damage of nitrites. In this study, a robust, rapid, and sensitive method is proposed for nitrite detection in pickled food, in which Au@Ag nanoparticles are used as a reliable surface-enhanced Raman spectroscopy (SERS) substrate taking advantage of the high enhancement effect of silver and the good stability of gold. Nitrites were anchored to the surface of the SERS substrate by bridging with 4-aminophenylthiophenol (PATP). With Raman scattering cross-section amplification and internal calibration by PATP, a satisfactory linear relationship (R 2 = 0.987) was established for nitrite detection in the concentration range of 5.00–100.00 μM, and the limit of detection (LOD) was 0.17 μM. This SERS-based method demonstrated high selectivity, good precision (RSD < 7.00 %), and satisfying recovery rates (101.42–107.35 %) in real samples, thus improving the determination method for nitrites. Therefore, this method has application potential in food safety and supervision.
研究领域:
食品安全
·
分析化学
·
光谱学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Zhe Wu,Yingjie Wang,Yufei Wang,Kaining Zhang,Yongchao Lai
Malondialdehyde (MDA) is an endogenous genotoxic product of lipid peroxidation and its accumulation in the human body is associated with various diseases. To accurately understand the role of MDA in physiological and pathological processes, it is of great significance to develop a robust and reliable method for rapid detection of MDA. Hence, we proposed a surface-enhanced Raman spectroscopy (SERS) based method for MDA analysis, which employed 4-aminophenylthiophenol (PATP) as a SERS microprobe to recognize and quantify MDA. Qualitative analysis of MDA was performed using the fingerprint Raman spectrum of MDA adducts, and quantitative analysis of MDA was conducted using the characteristic peak of PATP at 1083 cm −1 as the internal standard. MDA detection can be performed in a mild reaction environment and the detection limit was below 0.50 μM. The proposed method successfully detected MDA in fresh blood samples and found satisfactory recovery rates in spiked samples. The proposed method allows reliable detection of endogenous toxic compounds in blood plasma, which is of great significance for monitoring oxidative stress indicators, such as lipid peroxidation rate and intensity, potential antioxidant capacity, and the degree of tissue peroxidation damage.
研究领域:
分析化学
·
生物化学
·
医学诊断
✓ 已验证
产品关联
DOI
高影响因子
DYES AND PIGMENTS
·
2025
·
IF 4.2
Ling Chen,Xu Guo,Wenjing Du,Jifang Shang,Duo Yang,Dongdong Li,Shaohui Liu,Zhiwei Ma
Solution-processed zinc oxide nanoparticles (NPs) films are recognized as efficient electron transport layers (ETLs) for quantum dot light-emitting diodes (QLEDs), offering both good stability and high efficiency. However, due to the inherently high work function of such films, exciton quenching occurs at the QDs/ZnO interface in these QLEDs, thereby compromising performance. In this study, we propose a simple surface modification method for solution-processed magnesium-doped ZnO (ZnMgO) ETLs treated with 4-methylthiophenol (MTP). The effects of MTP treatment on the chemical, morphological, and electrical properties of thin films based on colloidal ZnMgO NPs were meticulously analyzed. For the first time, the proposed MTP-modified ZnMgO films were applied in QLEDs to investigate the impact of surface modification of the ETLs on device performance. The optimization of charge balance and the prevention of QD emission quenching were successfully decoupled. Full-color QLEDs utilizing the MTP-modified ZnMgO ETLs demonstrated impressive peak external quantum efficiencies: 10.27 % for blue-QLEDs, 21.03 % for green-QLEDs, and 17.41 % for red-QLEDs. Moreover, by modifying the surface of ZnMgO with MTP, the sensitivity of ZnMgO to water molecules was significantly reduced, thereby enhancing the stability of ZnMgO NPs. Consequently, these QLEDs featuring more stable ZnMgO exhibit extended lifetimes with T 50 values of 105,422 h (red), 48,071 h (green), and 187 h (blue). This discovery offers a novel strategy for improving the efficiency and lifetime of QLEDs by employing MTP-treated ZnMgO NPs as the ETLs.
研究领域:
材料科学
·
纳米技术
·
光电子学
·
半导体器件
·
薄膜技术
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Yafang Pan,Xiaolong Song,Shi Wang,Shuguang Li,Mingli Wang
Combining the advantages of semiconductors and precious metals to produce highly sensitive Surface-enhanced Raman scattering (SERS) substrates. In this paper, Cu 2 O@Ag core-shell particles were prepared, optical fibers were selected as substrates to strengthen the portability of SERS substrates, optical fiber SERS probes were prepared by electrostatic adsorption method and chemical bonding method, and the performance of SERS probes prepared by the two methods under the same deposition time was discussed, which it was found that the optical fiber probes prepared by chemical bonding method had better Raman enhancement effect. Rhodamine 6G(R6G) was used as the detection molecule to investigate the detection limit, uniformity, reproducibility of fiber SERS probe. 4-nitrophenyl thiophenol (4-NTP) is an organic molecule used in the synthesis of pesticides and dyes, excessive use can be harmful, it was found that the detection concentration of 4-NTP is as low as 10 −6 M, and the detection limit of the optical fiber SERS probe is used to detect thiram in pears, which its detection limit is 0.5 mg/L, which is far lower than the national standard of the United States and China (5 mg/L). The above experimental results show that an excellent fiber optic SERS probe has been successfully developed.
研究领域:
分析化学
·
生物传感器
·
纳米材料学
·
光子学
·
食品安全检测
·
分子诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 44
·19270-19275
·
IF 3.288
Bingyan Han,Ze Xin,Qifang Yan,Qin Yan,Jingmei Jiang
Highly ordered metal nanoclusters (NCs) have attracted much attention due to their controllability and regularity. Herein, self-assembled CuNCs with orange-red emission were prepared using m-aminothiophenol (m-AT) within 10 s. The hydrogen bonding interactions of CuNCs@m-AT were controlled precisely by adjusting the pH, and this induced the continuous self-assembly process of monodisperse, nano-spheres, nano-meshes and nano-sheets, and established the relationship between the macrostates and the microstructures of CuNCs@m-AT. For the first time, an organic anion was used to induce the emission of CuNCs@m-AT and to carry out the phase transfer of CuNCs@m-AT from the aqueous phase to the n-butanol phase. In addition, we found that m-AT was more beneficial for the synthesis of CuNCs, compared to o-AT and p-AT. This work provides an example of the structure-dependent CuNCs@m-AT on luminescent properties and showed the potential of –NH2 in the design of superstructures of nanoscale materials with unique functions and properties.
研究领域:
纳米技术
·
材料科学
·
化学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2021
·
IF 5.097
Yi Chen,Haojing Yin,Debabrata Sikdar,Linglin Yan,Zheng Zhou,Jiacen Sun,Chuan Wang
The self-assembly of plasmonic building blocks into superlattices has emerged as a promising route to fabricate metamaterials with customizable nanoscale architecture and collective properties. However, self-assembly of such plasmonic superlattice has proven challenging, owing to the low packing fraction, complex interparticle forces, and local heterogeneity. Besides, the conventional assembly of small nanoparticles usually exhibits localized defects and uncontrollable electromagnetic field distribution, limiting its functionality for real-world application. Here, we report on the self-assembly of multifacet gold nanopolyhedron (AuNPH) into high-quality giant plasmonic superlattice sheets. This bottom-up method involves soft ligand-balanced crystallization of AuNPHs in conjunction with drying-mediated self-assembly. Such AuNPHs superlattice sheets exhibit macroscopic surface area while maintaining a highly ordered nanoscopic structure. We also demonstrate by both experiment and theoretical simulation that the surface-plasmon-induced hotspots are uniformly distributed across the sheet surface, facilitating its application as flexible surface-enhanced Raman scattering (SERS) sensors for detection of 4-aminothiophenol. The Raman enhancement factor (EF) of this flexible SERS sensor can reach 1.7 × 106 with a detection limit reaching the nanomolar scale. Moreover, the Raman signals exhibited high homogeneity across the superlattice sheets with a low relative standard deviation of 4.3%. Such flexible AuNPHs superlattice sheets can be applied as nonconventional SERS platforms with well-defined customizability, suggesting a robust and efficient avenue for real-world applications in high-sensitive inspection of drugs, explosives, and environmental pollutants.
研究领域:
材料科学
·
纳米技术
·
分析化学
·
传感技术
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Yuan Chen,Xiao-Mi Liu,Xi Wu,Xue-Chen Liu,Wen-Hao Dong,Bing-Kai Han,Xin Du,Cong Zhang,Yan-Yan Zhang,Hong-Tao Wang,Qiang Chen
Novel approachs to functionalize carboxylated multi-walled carbon nanotubes (CMWCNTs) array with poly- l -histidine (PLH) on a self-assembled monolayer (SAM) of 4-aminothiophenol (4ATP) were developed for the first time. With help of π–π interaction and chelation of the side imidazole groups in poly- l -histidine, the array showed efficient electron transfer and mild biocompatibility. By immobilizing glucose oxidase (GOx) to AuNPs electrodeposited on the array, a high-powered glucose biosensor with excellent electrocatalytic performance was fabricated and applied for glucose determination in human serum samples. The prepared biosensor exhibited highly sensitive response to glucose under the operating voltage of 600 mV with sensitivity of 96.04 μA mM −1 cm −2 , linear range of 0.005–6.5 mM, lowest detection limit (LOD) of 0.7 μΜ (S/N = 3) and Michaelis constant ( K M ) of 3.92 mM. Compared with other glucose sensors previously reported, this work showed higher sensitivity, lower detection limit and wider linear range. Furthermore, the developed array may provide a promising platform for various biosensors fabrication.
研究领域:
纳米技术
·
生物传感器
·
电化学
·
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2017
·
IF 2.536
Qiaoqiao Shi,Jie Huang,Yaning Sun,Mengqi Yin,Mei Hu,Xiaofei Hu,Zhijun Zhang,Gaiping Zhang
An ultrasensitive method for the detection of antibiotics in milk is developed based on inexpensive, simple, rapid and portable lateral flow immunoassay (LFI) strip, in combination with high sensitivity surface-enhanced Raman spectroscopy (SERS). In our strategy, an immunoprobe was prepared from colloidal gold (AuNPs) conjugated with both a monoclonal antibody against neomycin (NEO-mAb) and a Raman probe molecule 4-aminothiophenol (PATP). The competitive interaction with immunoprobe between free NEO and the coated antigen (NEO-OVA) resulted in the change of the amount of the immobilized immunoprobe on the paper substrate. The LFI procedure was completed within 15 min. The Raman intensity of PATP on the test line of the LFI strip was measured for the quantitative determination of NEO. The IC 50 and the limit of detection (LOD) of this assay are 0.04 ng/mL and 0.216 pg/mL of NEO, respectively. There is no cross-reactivity (CR) of the assay with other compounds, showing high specificity of the assay. The recoveries for milk samples with added NEO are in the range of 89.7%–105.6% with the relative standard deviations (RSD) of 2.4%–5.3% ( n = 3). The result reveals that this method possesses high specificity, sensitivity, reproducibility and stability, and can be used to detect a variety of antibiotic residues in milk samples.
研究领域:
分析化学
·
食品安全
·
生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）