Catalysts
·
2021
·Vol. 11
·期 3
·370
·
IF 4.146
Yue Yang,Xiaochen Liu,Yuanjie Xu,Xing Gao,Yihu Dai,Yu Tang
Hydrodeoxygenation (HDO) is one of the promising catalytic routes for converting biomass derived molecules to high value products. A key step of HDO is the cleavage of an aromatic C–O bond to accomplish the deoxygenation step, however, which is energetically unfavorable. Herein, we report a series of palladium (Pd)-incorporated α-phase of molybdenum carbide (α-MoC) mesoporous composites for enhanced HDO activity of a biomass model molecule, anisole. The catalysts, x%Pd/α-MoC (x% is the molar ratio of Pd/Mo), were investigated by X-ray diffraction (XRD), temperature programmed reduction (TPR), temperature programmed desorption (TPD), Brunauer–Emmett–Teller (BET), Raman, transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) techniques. Pd is highly dispersed on α-MoC when x% ≤ 1%, but aggregate to form nanoparticles when x% = 5%. The x%Pd/α-MoC catalysts (x% ≤ 1%) show enhanced HDO activity in terms of turnover frequency (TOF) and apparent activation energy barrier (Ea) compared with α-MoC and β-Mo2C catalysts. The TOF of 1%Pd/α-MoC catalyst at 160 °C is 0.115 h−1and the Ea is 48.2 kJ/mol. Moreover, the direct cleavage of aromatic C–O bond is preferred on 1%Pd/α-MoC catalyst. The enhanced HDO activity is attributed to superior H2dissociation ability by the highly dispersed Pd sites on carbide. This work brings new insights for rational design of the catalyst for selective C–O bond activation.Keywords:hydrodeoxygenation;carbide;palladium;anisole;biomass;C–O bond cleavage
研究领域:
催化
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化学工程
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材料科学
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产品关联
DOI
高影响因子
PHYTOTHERAPY RESEARCH
·
2025
·
IF 6.3
Qing Ning,Yingxue Yue,Xinlian Liu,Wenbo Ji,Qin Zhao,Jing Wang,Zhenhai Zhang
S afe and effective treatments for psoriasis are limited. Anisole is an active ingredient in citrus and basil volatile oils; however, its potential for psoriasis treatment remains unexplored. To investigate the effects and mechanism of anisole transdermal administration as a treatment for psoriasis. Imiquimod (IMQ) was used to establish a C57 mouse psoriasis model. The severity of psoriasis lesions in each group was assessed by evaluating the thickness of skin lesions, erythema, and scales. Pathological changes within the epidermis organization were evaluated via hematoxylin and eosin (H&E) staining using light microscopy. Serum inflammatory factor levels were measured by enzyme-linked immunosorbent assays. Real-time quantitative polymerase chain reaction (RT-qPCR) and western blotting (WB) were performed to analyze the mRNA levels of relevant inflammatory factors and the expression of key proteins at the skin lesion sites in psoriatic mice. In model mice, applying anisole hydrogels significantly reduced the serum levels of pro-inflammatory factors interleukin (IL)-17A, (IL)-23, tumor necrosis factor (TNF)-α, and interferon (IFN)-γ. H&E staining revealed significantly attenuated stratum spinosum thickening and lymphocyte infiltration in the treatment group. RT-qPCR results further demonstrated that the skin tissues from the treatment group exhibited significantly reduced Il1b , Il17a , Il22 , and Tnfa mRNA expression. Western blotting revealed inhibition of the JAK1/STAT3 signaling pathway within anisole-treated psoriatic tissues. Anisole potentially reduces psoriatic-associated inflammation through the JAK1/STAT3 signaling pathway, alleviating IMQ-induced psoriasis.
研究领域:
皮肤病学
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免疫学
·
药理学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2013
·Vol. 48
·期 11
·2324-2330
·
IF 1.24
Ming Cai,Xiangyang Guo,Hanhua Liang,Peilong Sun
Summary In this study, microwave-assisted extraction with ethanol (MAEE) of star anise oil from Illicium verum Hook.f . has been optimised by response surface methodology (RSM). A maximum yield of star anise oil was obtained at an optimum condition: the ratio of solvent to sample 17 mL g −1 , extraction time 16 min and microwave power 505 W. Accordingly, the highest yield of star anise oil was about 24.98%, which was much higher than that of steam distillation (SD), 7.17%. Oxygenated organic compounds in representative of trans-anethole are a major component in star anise oil, nearly 94.21% for SD and 86.66% for MAEE, identified and determined by GC-MS. The oils extracted by SD and MAEE both have strong antioxidant activities that were demonstrated by the DPPH and ABTS assays.
研究领域:
植物化学
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食品科学
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分析化学
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产品关联
DOI
高影响因子
MEDIATORS OF INFLAMMATION
·
2023
·
IF 4.6
Xu-Hui Li,Li Liu,Wen-Zhong Wu
Ulcerative colitis (UC) is the most common inflammatory bowel disease (IBD); it is incurable, and the treatment is expensive. Trans-anethole (TA), the main component of fennel, exhibits various biological activities. An increasing number of studies have demonstrated the efficacy of herbal active ingredients in the treatment of UC. This study aimed to investigate the effect and mechanism of TA in UC. In this study, we have experimented on mice with dextran sulfate sodium salt (DSS)-induced UC. The TA group was gavaged with 62.5 mg/kg TA by gavage once daily on days 8–14. To observe the effect of TA on the colon tissue, various investigations were performed, including western blot and immunohistochemistry for intestinal barrier protein expression, TUNEL staining for apoptosis, western blot, and ELISA for inflammation level, flow cytometry for Th17/Treg, LC–MS for blood bile acid content, GC–MS for blood fatty acid content, and 16s RNA for intestinal contents. TA alleviated weight loss in mice with UC; increased colon length; alleviated intestinal mucosal damage; upregulated claudin-1, occludin, and ZO-1 protein expression levels; reduced inflammatory factors in the colon and serum; and alleviated apoptosis. TA reduced fatty acid and bile acid levels by inhibiting colony abundance and reducing Th17/Treg cell differentiation in the colon. We found that TA alleviates DSS-induced UC by remodeling the intestinal flora to regulate immunity and bile acid metabolism.
研究领域:
药理学
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免疫学
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胃肠病学
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微生物学
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DOI
PubMed
高影响因子
Reaction Chemistry & Engineering
·
2023
·Vol. 8
·期 6
·1464-1475
·
IF 3.9
Long Chen,Yixuan Liu,Heng Zhang,Yuncong Li,Songdang Zhang,Yulin Hu,Hu Li,Song Yang
Utilization of renewable biomass resources to transform them into value-added platform molecules has aroused widespread attention. Anethole (AN) is widely considered to be a significant chemical owing to its extensive application in food additives, daily necessities and pharmaceuticals. Therefore, reducing the dependence on natural fennel oil is a rational approach. We report a “green” and effective pattern of stereoselective conversion of biomass-derived 4′-methoxyphenylacetone (4-MOPP) into trans-AN. We employed a “domino” strategy of catalytic transfer hydrogenation and dehydration promoted by an interesting Lewis/Brønsted bifunctional acid catalyst, which was developed by template-free self-assembly of Hf4+ and phenylphosphonic acid (PA) followed by grinding sulfonation. Importantly, by simply adjusting composite components, PA–Hf–SO3H (1.5 : 1) exhibited a favorable amorphous inorganic–organic structure with specific surface area (135.59 m2 g−1), affluent mesopores (4.01 nm), indispensable Lewis/Brønsted acidic sites, as well as strong hydrophobicity and stability. The optimal reaction conditions were investigated by the single-factor method and response surface methodology; a high yield of 98.3% with excellent reusability was demonstrated. The corresponding kinetic and thermodynamic parameters were determined, and a feasible reaction mechanism proposed. Finally, the developed model showed a wide range of substrate versatility, thereby providing a promising catalytic strategy for the effective synthesis of AN or other high-value molecules.
研究领域:
催化化学
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绿色化学
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材料科学
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产品关联
DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
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2021
·
IF 5.645
Zhunjing Wang,Yongjian Xie,Maidinai Sabier,Tao Zhang,Jianyu Deng,Xuming Song,Zhihong Liao,Qingguang Li,Shengxiang Yang,Yang Cao,Xingquan Liu,Guoxin Zhou
The safe storage and protection of grain includes the exploitation of plant-based fumigants as a green control technology. This study first determined the fumigant toxicity of 12 traditional Chinese medicinal plants against adults of the rusty grain beetle, Cryptolestes ferrugineus (Stephens), one of the most ubiquitous and pestilent grain storage pests worldwide. Exposure to volatiles released from Illicium verum Hook. f. powder was found to be by far the most lethal. Illicium verum power and its volatiles eluent were then confirmed to be highly effective in killing both larvae and adults of C. ferrugineus . Star anise volatiles also showed good biological activity against Lasioderma serricorne (Fabricius) and Sitophilus zeamais Motschulsky, but not Tribolium castaneum Herbst. No significant differences were found in mortality of the adults of the rusty grain beetle when exposed at different temperatures ranging from 15−35°C. Gas chromatography-mass spectrometry (GC–MS) analysis showed that the main components of the eluent of star anise powder were trans -anethole (62.60%), estragole (23.70%), linalool (3.66%) and d -limonene (2.15%). In the fumigation test using synthetic standards of these four chemicals, only trans -anethole showed effective biological activity with exposure to 30 mL/L trans -anethole for 24 h resulting in 100% mortality of rusty grain beetle adults. Estragole did significantly enhance fumigant efficiency of trans -anethole. We further found that trans -anethole affects the beetles acetylcholinesterase activity, which was inhibited and decreased by 64.48% within 24 h. The results therefore show that trans -anethole, the major component of star anise volatiles contributes to its fumigant toxicity against C. ferrugineus by, at least partly, affecting its insect nervous system. Hence, star anise or its biologically active substances show very good potential to be used as a botanical insecticide to control C. ferrugineus .
研究领域:
昆虫学
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害虫防治
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植物化学
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产品关联
DOI
高影响因子
Food and Bioprocess Technology
·
2017
·Vol. 10
·期 10
·1844-1853
·
IF 2.576
Ye Youxin,Zhu Mingjin,Miao Keyan,Li Xinying,Li Defu,Mu Changdao
Antimicrobial activity is an attractive property for packaging materials which can extend the shelf life of products and provide microbial safety for consumers. The study aimed to analyze the physicochemical and antimicrobial properties of gelatin-based edible films containing trans -anethole as the active additive. Encapsulation with β-cyclodextrin was used as an effective way to introduce trans -anethole into gelatin matrix. The results showed that the trans -anethole/β-cyclodextrin inclusion complex could be evenly dispersed in the gelatin-based edible films with appropriate addition. The incorporation of trans -anethole conferred the edible films with good antimicrobial activity as expected, which increased with the content of trans -anethole increasing. Moreover, the addition of inclusion complex improved the tensile strength and surface hydrophobicity and reduced the moisture content of the edible films. It was interesting that the edible films presented great UV light barrier property and it was increased by the addition of inclusion complex. Overall, the antimicrobial gelatin-based edible films showed great potential as bioactive packaging materials to extend food shelf life.
研究领域:
食品科学
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包装材料
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生物技术
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产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2015
·
IF 2.818
Wenwen Zhang,Xinying Li,Taocheng Yu,Lun Yuan,Gang Rao,Defu Li,Changdao Mu
Trans -anethole (AT) has a variety of antimicrobial properties and is widely used as food functional ingredient. However, the applications of AT are limited due to its low water solubility, strong odor and low physicochemical stability. Therefore, the aim of this work was to encapsulate AT with β-cyclodextrin (β-CD) for obtaining inclusion complex by co-precipitation method. The measurements effectively confirmed the formation of inclusion complex between AT and β-CD. The results showed that the inclusion complex presented new solid crystalline phases and was more thermally stable than the physical mixture and β-CD. The phase solubility study showed that the aqueous solubility of AT was increased by being included in β-CD. The calculated stability constant of inclusion complex was 1195 M − 1 , indicating the strong interaction between AT and β-CD. Furthermore, the release study suggested that β-CD provided the protection for AT against evaporation. The release behavior of AT from the inclusion complex was controlled.
研究领域:
食品科学
·
药学
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化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Shuwei Wang,Tianyu Dong,Ruijia Liu,Jie Sun,Haitao Chen
Pork is one of the meats widely consumed all over the world, while stewing is preferred because it can retain the nutritional content of the meat. After stewing, pork still retains some odors, such as bloody aroma, which affects the flavor quality. Therefore, people often add spices during the stewing process to reduce the off-flavor, but the mechanism of the effect of spices on the off-flavor has not been clarified. This study examined the pork broth before and after the addition of spices and determined the off-flavor compounds ( (E) -2-nonenal, (E) -2-heptenal, acetic acid, and valeric acid) in pork broth and key spice compounds (linalool, 1,8-cineole, and (E) -anethole) in pork broth with spices. The mechanism of the influence of spices on the off-flavor compounds of pork broth was clarified through the sensory perceptual interaction between off-flavor compounds and key spice compounds. The S-curve method was used to analyze the perceptual interactions between off-flavor compounds and key spice compounds. The results showed that linalool, 1,8-cineole, and (E) -anethole all had a masking effect on the aroma of off-flavor compounds (S-curve ratios = 1.58, 2.21, and 5.84, respectively), and the inhibitory effect was strongest when the three compounds acted together (S-curve ratio = 42.49).
研究领域:
食品化学
·
风味科学
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感官分析
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食品加工
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）