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CHEMICAL ENGINEERING SCIENCE · 2024 · IF 4.1

Self-assembled copper herbal carbon dots nanosheets with powerful antibacterial properties: A robust cascade antioxidant nanozyme for scavenging reactive oxygen species

Junjie Deng,Bowen Zhang,Yuye Zhong,Donglei Fu,Aoping Zhu,Xinghai Liu

Oxidative stress is a growing concern, necessitating more effective antioxidants for complex environments. Herein, we developed a composite nanozyme, DVI-CDs-Cu, with exceptional antioxidant and antibacterial properties by utilizing DVI-CDs derived from Chinese herbs: Dandelion, Violet, and Isatis root, complexed with Cu 2+ ions. The DVI-CDs with abundant surface functional groups exhibited excellent superoxide dismutase-like (SOD-like) activity while forming stable complexes with copper ions. The attached copper ions performed the peroxidase-like (POD-like) function and formed a cascade effect, greatly enhancing the antioxidant capacity of the DVI-CDs-Cu nanozyme and strengthening its antibacterial property. The nanozyme was able to comprehensively clear 90 % of reactive oxygen species (ROS) while killing approximately 98 % of bacteria. The potential application of the nanozyme as a ROS scavenger was demonstrated by exploring its application to cigarette filters, capable of eliminating approximately 80 % of ROS. This provides a new case for the design and development of CDs-metal ions synergistic bionano-enzymes.

CAS / MDL: 7558-80-7 54827-17-7
研究领域: 材料科学 · 纳米技术 · 生物医学工程 · 药学 · 抗菌研究 · 抗氧化研究
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