CARBOHYDRATE POLYMERS
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2025
·
IF 12.5
Chunan Lu,Qili Sun,Zimo Li,Yushan Wei,Jialin Yu,Shiman Li,Yansong Wang,Kai Li,Chuqing Tang,Huicheng Cao,Jingle Chen,Qianqian Liu,Xiajun Liang,Shujiang Zhang,Chao Xie,Bin Tang
Wound healing remains a significant clinical challenge, particularly for chronic and non-healing wounds, which impose substantial burdens on patients and healthcare systems. Despite advances in wound care, traditional dressings lack therapeutic properties and can impede the healing process due to their inability to conform to irregular wound geometries and lack of self-healing capabilities. This study addresses these limitations by introducing an innovative, injectable Glycyrrhizic acid ammonium salt/Pectin@Strontium (GAAS/Pec@Sr) hydrogel dressing. The hydrogel is derived from natural ingredients and possesses multifunctional therapeutic properties, including bioabsorbability, self-healing, and the ability to promote blood vessel and collagen regeneration while exhibiting anti-inflammatory and immunomodulatory functions. We developed the GAAS/Pec@Sr hydrogel through a combination of rheological experiments, gene and protein expression studies, and in vivo testing in a rat skin injury model. The GAAS/Pec@Sr hydrogel represents a promising biomaterial for wound healing, offering a novel solution derived entirely from natural products that can significantly contribute to the field of regenerative medicine.
研究领域:
生物材料学
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再生医学
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药理学
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DOI
PubMed
高影响因子
Scientific Reports
·
2021
·Vol. 11
·期 1
·1-13
·
IF 4.38
Ma Xuemei,Yu Jiayi,Jing Jing,Zhao Qian,Ren Liyong,Hu Zhiyong
Pectin is a kind of natural and complex carbohydrates which is extensively used in food, chemical, cosmetic, and pharmaceutical industries. Fresh sunflower ( Helianthus annuus L.) heads were utilized as a novel source of pectin extracted by ammonium oxalate. The conditions of the extraction process were optimized implementing the response surface methodology. Under optimal extraction parameters (extraction time 1.34 h, liquid–solid ratio 15:1 mL/g, ammonium oxalate concentration 0.76% (w/v)), the maximum experimental yield was 7.36%. The effect of spray-drying and freeze-drying on the physiochemical properties, structural characteristics, and antioxidant activities was investigated by FT-IR spectroscopy, high performance size exclusion chromatography, and X-ray diffraction. The results showed freeze-drying lead to decrease in galacturonic acid (GalA) content (76.2%), molecular weight ( M w 316 kDa), and crystallinity. The antioxidant activities of pectin were investigated utilizing the in-vitro DPPH and ABTS radical-scavenging systems. This study provided a novel and efficient extraction method of sunflower pectin, and confirmed that different drying processes had an effect on the structure and properties of pectin.
研究领域:
食品科学
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化学工程
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药学
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生物技术
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Yu Bai,Lu Zhou,Keke Ma,Hongjie Zhou,Yiying Xin
This study was conducted to access the catalytic performances and reaction mechanisms of Graphene Electroactive Membrane (GEM). The GEM was prepared by vacuum-pressing method, and characterized by FESEM and FTIR. Catalytic performances were measured in the index of decolorization ratio and mineralization rate. Active species were recognized by scavengers for investigating reaction mechanisms. The impacts of current intensity and water flux on catalytic performances were presented to illustrate the mechanisms of GEM electro-catalysis deeply. According to the results, the method of GEM preparation was reliable and Graphene was an appropriate material for Electroactive Membrane (EM). Compared with EM electro-catalysis and GEM with no electro-catalysis (GEM-NEC), the mineralization rate increased by 56.1% and 28.8% respectively, and the decolorization rate increased by 45.5% and 29.8% respectively. The decolorization rate of GEM electro-catalysis with 0.2 M Ammonium Oxalate (Scavenger of electron hole) decreased 32.7% more than GEM electro-catalysis with no scavenger. Thus, direct oxidation was the main mechanism of GEM electro-catalysis, which was very different from traditional electro-catalysis. When current intensity was less than 20 mA and water flux was higher than 3 mL/min, decolorization ratio increased dramatically. Thus, electro-catalytic process and adsorption-diffusion process played important roles in GEM electro-catalysis process. The GEM electro-catalysis was an effective and stable advanced wastewater treatment for removal of organic pollutants.
研究领域:
环境工程
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化学工程
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材料科学
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DOI
高影响因子
ChemCatChem
·
2016
·Vol. 8
·期 12
·2128-2135
·
IF 4.724
Kui Li,Xin Xie,Wei-De Zhang
A facile strategy to synthesize porous graphitic carbon nitride with stacking nanotubes by thermal condensation of melamine–ammonium oxalate stacking sheets is reported. The photocatalytic generation rate of hydrogen over the porous graphitic carbon nitride (99.7 μmol h −1 ) is nearly 9.5 times as that of pristine g-C 3 N 4 (10.5 μmol h −1 ). Such enhancement is attributed to the large specific surface area (91.1 m 2 g −1 ), improved visible-light absorption and efficient separation of photogenerated electrons and holes. The strategy of preparing the porous graphitic carbon nitride with modified melamine as a precursor opens a new gate for the regulation of the morphologies of g-C 3 N 4 to get higher photocatalytic activity. Graphical Curled up : Porous graphitic carbon nitride nanotubes were prepared by thermal condensation of melamine–ammonium oxalate (MAO) stacking sheets, which display high and stable activity for photocatalytic generation of hydrogen through water splitting.
研究领域:
材料科学
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光催化
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纳米材料
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能源化学
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半导体催化
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水裂解制氢
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功能材料
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Xinghui Wu,Lina Yang,Mingjie Xia,Kejin Yu,Wenqi Cai,Taiyuan Shi,Mengxi Xie,He Liu
The stable energy barrier of mucin and soy hull polysaccharide (SHP) is established at the air/water interface in the intestinal fluid and is conducive to the absorption and transportation of nutrients. This study aimed to investigate the effect of different concentrations (0.5 % and 1.5 %) of Na + and K + on the energy barrier through the digestive system model in vitro . The interaction between ions and microwave-assisted ammonium oxalate-extracted SP (MASP)/mucus was characterized by particle size, zeta potential, interfacial tension, surface hydrophobicity, Fourier transform infrared spectroscopy, endogenous fluorescence spectroscopy, microstructure, and shear rheology. The results showed that the interactions between ions and MASP/mucus included electrostatic interaction, hydrophobic interaction, and hydrogen bond. The MASP/mucus miscible system was destabilized after 12 h, and the ions could improve the system stability to some extent. MASP aggregated continuously with the increase in the ion concentration, and large MASP aggregates were trapped above the mucus layer. Furthermore, the adsorption of MASP/mucus at the interface increased and then decreased. These findings provided a theoretical basis for an in-depth understanding of the mechanism of action of MASP in the intestine.
研究领域:
食品科学
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营养学
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生物物理学
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Wenhao Ding,Guolang Zhou,Xiangjie Guo,Cheng Liu,Tianshi Wang,Yongsheng Fu,Jingzhou Yin,Lili Zhang,Edison Huixiang Ang
The natural reactivity of Zn metal in aqueous environments leads to surface deterioration and uncontrolled dendrite growth, posing challenges in the advancement of Zn-ion batteries. In this research, we introduce an environmentally friendly and cost-effective electrolyte additive, ammonium oxalate (AO), to significantly extend the cycle life of Zn-ion batteries with minimal usage. Oxalate ions within AO actively participate in the solvation of hydrated Zn ions and attach to the Zn anode surface prior to H 2 O molecules, creating a robust solid-electrolyte interface (SEI) layer. This SEI layer serves a dual purpose: it inhibits further reactions with H 2 O and restricts the two-dimensional movement of Zn ions, promoting the preferential growth of the (0 0 2) crystal plane. Consequently, Zn||Zn cells exhibit an impressive lifespan surpassing 1800 h (at 1 mA cm −2 , 1 mAh cm −2 ), and Zn||Cu cells experience a tenfold increase in cycling life. Moreover, Zn||MnO 2 full cells, incorporating this low-cost and highly efficient inorganic additive, maintain an outstanding 80.84 % capacity retention after 1200 cycles at 1 A g −1 . This breakthrough with AO offers a promising avenue for the practical implementation of Zn-ion batteries, emphasizing their cost-effectiveness and environmental sustainability.
研究领域:
材料科学
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电化学
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能源存储
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DOI
高影响因子
Science China-Materials
·
2023
·Vol. 66
·期 6
·2274-2282
·
IF 8.1
Zhang Yang,Cao Ning,Liu Xiaoming,He Fengting,Zheng Bin,Zhao Chaocheng,Wang Yongqiang
Graphite carbon nitride (g-C 3 N 4 ) has become an emerging metal-free photocatalyst and attracted the attention of researchers. However, pure g-C 3 N 4 (PCN) prepared by traditional thermal condensation polymerization has a low polymerization of heptazine ring chains and a large number of charge recombination centers, which hinder in-plane charge transport, leading to undesirable photocatalytic performance. Herein, PCN fabrication by thermal treatment with ammonium oxalate monohydrate was performed to produce highly dispersed porous g-C 3 N 4 nanosheets, and the integrity of their in-plane heptazine ring chains was successfully improved without introducing heteroatoms. Electron paramagnetic resonance and 13 C nuclear magnetic resonance analyses revealed significantly increased electron density and delocalization of the π-conjugated structure. The obtained samples exhibited acceptable stability and photocatalytic activity, and the hydrogen reduction rates without and with the Pt co-catalyst were 11.2 and 5.3 times that of PCN.
研究领域:
材料科学
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化学
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光催化
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纳米技术
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DOI
高影响因子
LETTERS IN APPLIED MICROBIOLOGY
·
2021
·Vol. 73
·期 6
·779-792
·
IF 2.858
Yang R.,Yin D.,Yang D.,Liu X.,Zhou Q.,Pan Y.,Li J.,Li S.
This study aims to explore the potential mechanisms of Xinnaokang in atherosclerosis treatment. Firstly, the active components of Xinnaokang were analysed by HPLC, which contains ginsenoside Rg1, puerarin, tanshinone, notoginsenoside R1, ammonium glycyrrhizate and glycyrrhizin. Network pharmacology analysis showed there were 145 common targets of Xinnaokang, including the chemical stress, lipid metabolite, lipopolysaccharide, molecules of bacterial origin, nuclear receptor and fluid shear stress pathways. Then, the animal experiment showed that Xinnaokang reduced the body weight and blood lipid levels of atherosclerotic mice. Vascular plaque formation was increased in atherosclerotic mice, which was markedly reversed by Xinnaokang. In addition, Xinnaokang reduced CAV‐1 expression and increased ABCA1, SREBP‐1 and LXR expressions in the vasculature. Xinnaokang promoted SREBP‐2 and LDLR expressions in the liver but decreased IDOL and PCSK9 expressions, indicating that Xinnaokang regulated lipid transport‐related protein expression. Cecal microbiota diversity was reduced in atherosclerotic mice but increased after Xinnaokang treatment. Xinnaokang treatment also improved gut microbiota communities by enriching Actinobacteria, Bifidobacteriales and Bifidobacteriaceae abundances. Metabolic profile showed that Xinnaokang significantly reduced homogentisate, phenylacetylglycine, alanine and methionine expressions in the liver of atherosclerotic mice. Xinnaokang effectively alleviated atherosclerosis, and this effect might be linked with the altered features of the liver metabolite profiles and cecal microbiota.
研究领域:
药理学
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心血管疾病
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微生物学
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代谢组学
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Haidong Luo,Shengjiang Zhang,Fozia Batool,Suhang Chen,Fengqi Zhao,Kangzhen Xu
The construction of an S-scheme heterostructure is considered as a promising strategy for enhancing photocatalytic performance. Herein, a three-dimensional Bi 5 O 7 I (BOI) microsphere decorated with Bi 2 Sn 2 O 7 (BSO) nanoparticles was prepared for the first time via a simple ultrasonic-assisted electrostatic self-assembly strategy and used for the degradation of 2,4-dinitrophenylhydrazine. 3 wt% Bi 2 Sn 2 O 7 /Bi 5 O 7 I has the highest degradation activity (93.7 %), with an apparent rate constant of 0.0848 min −1 , which is 2.55 times that of the original Bi 5 O 7 I (0.0333 min −1 ). Moreover, the optimal binary heterojunction photocatalyst has good reusability and universal applicability. The results of cyclic voltammetry tests clarify that the optimal photocatalyst can provide more surface reactive sites. The results of radical trapping experiments and electron spin resonance indicate that holes (h + ) and superoxide radicals are the main active radicals in the degradation process of 2,4-dinitrophenylhydrazine. Photoelectrochemical and photoluminescence confirm that 3 wt% Bi 2 Sn 2 O 7 /Bi 5 O 7 I composites exhibit the highest separation rate of photogenerated carriers. Finally, based on the results of experimental studies and theoretical calculations, the S-scheme charge transfer path on Bi 2 Sn 2 O 7 /Bi 5 O 7 I composite is determined. This work provides a new perspective on how to design high-performance S-scheme bismuth oxyhalide-based heterojunction photocatalysts for solar energy conversion.
研究领域:
环境科学
·
材料科学
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DOI
PubMed
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Yu-Ting Huang,Zheng Li,Cheng Yuan,Yuan-Cheng Zhu,Wei-Wei Zhao,Jing-Juan Xu
Neuromorphic perception capable of multisensory integration (MSI) in electrolytes is important but remains challenging. Here, the aqueous implementation of artificial MSI is reported based on the newly emerged organic photoelectrochemical transistor (OPECT) by representative visual (light)-gustatory (sour) perception. Under the co-modulation of light and H + /OH − , multisensory synaptic plasticity and several typical MSI characteristics are mimicked, including “super-additive response,” “inverse effectiveness effect” and “temporal congruency.” To demonstrate its potential usage, different types of multisensory associative learning and corresponding reflex activities are further emulated. The chemical MSI system is also utilized to control artificial salivation by a closed loop of real-time perception, processing, integration, and actuation to emulate the biological responses toward external stimuli. In contrast to previous solid-state operations, this work offers a new strategy for developing neuromorphic MSI in aqueous environments that are analogous to those in biology.
研究领域:
生物医学工程
·
神经科学
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材料科学
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DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Xuewen Luo,Lei Xu,Leba Yang,Jiawen Zhao,Tewodros Asefa,Rongliang Qiu,Zhujian Huang
Non-free radical photocatalysis with metal oxide catalysts is an important advanced oxidation process that enables the removal of various emerging environmental pollutants, such as tetracycline. Here, four hexagonal La2O3 photocatalysts with different densities of oxygen vacancy and crystalline features are synthesized and then further treated by ball milling. Ball milling of these La2O3 photocatalysts is found to increase the amount of oxygen vacancies on their surfaces and thereby the amount of 1O2 species produced by them. The photocatalytic degradation of TC by these La2O3 photocatalysts depends on the oxygen vacancies present on them. Furthermore, the ones with a strong (101) diffraction peak remove tetracycline from water systems largely with 1O2 and •OH species, whereas those with a weak (101) diffraction peak do so mainly via 1O2 and direct electron transfer (DET) process. Their overall catalytic properties are also studied by density functional theory calculations. Moreover, the organic products produced from tetracycline by La2O3 photocatalysts containing a strong (101) diffraction peak are found to be less toxic than those produced by La2O3 photocatalysts containing a weak (101) diffraction peak. This study also provides convincing evidence that the structures of La2O3 determine the species that is produced by it and that end up mediating photocatalytic reaction pathways (i.e., free radical versus non-free radical) to degrade an emerging environment pollutant.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Hui Yang,Minghao Zhang,Junting Wang,Shengnan Wang,Shumin Wang,Lina Yang,Peng Wang,Hong Song,He Liu,Yutang He
The applications of polysaccharides as emulsifiers are limited due to the lack of hydrophobicity . However, traditional hydrophobic modification methods used for polysaccharides are complicated and involve significant mechanical and thermal losses. In this study, soy hull polysaccharide (SHP) and terminally aminopropylated polydimethylsiloxane (NPN) were selected to investigate the feasibility of a simple and green interfacial membrane strengthening strategy based on the interfacial polymerization of anionic polysaccharides and fat-soluble alkaline ligands. Our results show that deprotonated SHP and protonated NPN can be complexed at the water/oil (W/O) interface, reduce interfacial tension, and form a strong membrane structure. Moreover, they can quickly form a membrane at the W/O interface upon the moment of contact to produce stable all-liquid printing products with complex patterns. However, the molecular weight of NPN affects the complexation reaction. Consequently, this study has long-term implications to expanding the areas of application for anionic polysaccharides.
研究领域:
食品科学
·
材料科学
·
生物化学
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）