JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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2023
·Vol. 332
·期 4
·1047-1054
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IF 1.6
Hu Yichen,Ma Jiaju,Liu Tonghuan,Zhang Yongjie,Yu Yuhong,Sun Zhiyu,Fang Fang,Dong Tianhao,Zhao Yanhong,Zhou Gen
In this paper, three polymeric bases (styrene, vinyl toluene, methyl methacrylate (MMA)) plastic scintillators were synthesized by thermal and UV irradiation polymerization. The influences of the concentrations of the primary fluorescent agent 2.5-diphenyloxazole (PPO) and wave-shift agent 1,4-bis-2(5-phenyloxazoyl)benzene (POPOP) on plastic scintillators characterization were investigated. The results suggest that the maximum emission wavelength of synthesized plastic scintillators with different polymeric base are all around 423 nm matching with maximum response wavelength of general photoelectric devices, and its decay time with several nanoseconds has reached the same level as the EJ-200. The maximum light yield of the plastic scintillator was achieved when the mass ratio of PPO/POPOP is 1.0%/0.02% for the styrene plastic scintillators.
研究领域:
材料科学
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核技术
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产品关联
DOI
高影响因子
PROGRESS IN ORGANIC COATINGS
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2015
·
IF 2.358
Meng Li,Xihuai Qiang,Wei Xu,Hui Zhang
A novel anionic AFC-based waterborne polyurethane was synthesized by importing the fluorescent agent 7-amino-4-(trifluoromethyl)coumarin (AFC) into the polyurethane chains. Structure of the WPU-AFC was confirmed by Fourier transform infrared spectroscopy (FTIR) and UV–visible absorption spectroscopy. Number average molecular weight and average emulsion particle size for WPU-AFC were also determined. It was found that the fluorescence intensity of WPU-AFC decreased with the increasing temperature and was enhanced compared with that of AFC. The improved thermal stability of WPU-AFC could be attributed to the incorporation of benzopyrone units in the preformed urethane groups. Furthermore, the fluorescence of WPU-AFC emulsion was very stable for long-term storage and it was a promising agent utilized in the specific collagen fiber materials.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
ACS Applied Polymer Materials
·
2024
·
IF 4.4
Wanqin Gong,Jun Cheng,Dandan Pi,Chao Gao,Hantao Zou,Xueting Liu,Jincai Rao,Fushan Nie
The self-warning and thermal-induced self-healing microcapsules were fabricated by the interfacial in situ polymerization process, which consists of SiO2 as the shell material and epoxy resin, a thermal initiator, and a fluorescent agent as the core materials. The squeegee coating method was used to prepare the self-healing self-warning PVC-coated fabric. The microcapsules have a core–shell structure with an average particle size of 1.5 μm and a high sphericity with a coverage rate of 77% and excellent thermal stability below 320 °C. The PVC coating agent has good wettability with the microcapsules with a contact angle of 34.6 ± 0.9°. When cracks appear on the surface of the coated fabric containing microcapsules, the fluorescent agent and repair agent (epoxy resin and thermal initiator) will then flow out from the broken microcapsules and fill the cracks owing to the great wettability of the PVC coating agent with a contact angle of 44.2 ± 1.1°. Under UV light, the cut displays a yellow fluorescence line, indicating the location of the damage. After filling the cracks, the epoxy resin polymerizes with the thermal initiator at 120 °C. When the heating time reaches 6 h, the cuts in the fabric are healed, and the strength of the coated fabric reaches 699 N, thereby matching the original strength of 713 N before cutting.
研究领域:
材料科学
·
纺织工程
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DOI
高影响因子
ADVANCES IN POLYMER TECHNOLOGY
·
2015
·Vol. 36
·期 2
·137-144
·
IF 1.045
Saiqi Tian,Peikun Zhang,Haojun Fan,Yi Chen,Jun Yan,Bi Shi
A fluorescent fluorescent waterborne polyurethane (FWPU) was synthesized by conjugating fluorescer, isodium 4,4 ′ -bis[4-anilino-6-hydroxyethylamino-6-(2-choloronilino-1,3,5-triazin-2-yl)amino]stilbene-2,2 ′ -disulphonate (RSW), into polyurethane backbone as a chain extender. The expected structure of FWPU was confirmed by Fourier transform infrared, 1 H nuclear magnetic resonance, and UV−vis spectrophotometer, and the effect of fluorescer content, temperature, as well as quencher on the fluorescence performances of FWPU was investigated in detail. Results reveal that covalently conjugation has unconspicuous effect on optical performance, and FWPU shows similar fluorescence intensity to fluorescer RSW except for a red shift of about 10 nm in maximum absorption wavelengths. Further study finds that there is a positive correlation between the concentration of fluorescer and the fluorescence intensity of FWPU; however, the opposite effect is obtained when the concentration exceeds 1 × 10 −5 mol/L, which is attributed to the concentration self-quenching. Although high temperature will decrease the intensity of fluorescence, the fluorescence components in FWPU shows high resistance to fluorescence quencher and thermal decomposition as a consequence of chemical combination with the polymer chain.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
Frontiers in Oncology
·
2021
·
IF 6.244
Liang Dongxin,Tuo Xiaoqian,Wang Qing,Zhao Lanbo,Zhang Kailu,Wang Yiran,Feng Xue,Yin Panyue,Guo Lin,Liu Yu,Wang Lei,Han Lu,An Ruifang,Li Qiling
The lack of cytopathologists delays the advancement of screening for endometrial cancer. It was urgent to develop a new dye for rapid diagnosis. Our study aimed to synthesize a targeted folate receptor-α near-infrared (NIR) fluorescent agent, folic acid-zwitterionic NIR fluorophore (ZW-FA), and explore the feasibility for screening of endometrial cancer and precancerous change. Folic acid was conjugated with zwitterionic NIR fluorophore. The preparation of ZW-FA was validated by 1H NMR, mass spectrometric, ultraviolet spectra and fluorescence spectra. ZW-FA was incubated with endometrial cytology samples obtained from patients who underwent dilation and curettage or total hysterectomy. Diagnostic utility was calculated by applying laser confocal microscope, Image-J and statistical models, such as enumeration, receiver operating characteristic curve, logistic regression, support vector machine and decision tree were used. The purity of ZW-FA was > 95% determined by 1H NMR. ZW-FA had the strongest absorption peak at 633 nm in ultraviolet spectra. Photostability of ZW-FA was over 8 hours. In clinical validation, a total of 92 patients were enrolled. The cut-off value of ZW-FA was 49 in enumeration, which was used to distinguish the type of samples. Indicators about diagnostic utility are as follows: sensitivity 90.77%, specificity 62.96%, false-positive rate 37.04%, false-negative rate 9.23%, positive predictive value 85.51% and negative predictive value 73.91%. The samples processed by ZW-FA did not affect further Hematoxylin-Eosin staining and pathological diagnosis. It was an effective cytologic strategy for in vitro diagnosis of endometrial cancer and precancerous change by using ZW-FA.Clinical Trial Registration: http://www.chictr.org.cn/index.aspx, identifier ChiCTR1800020123.
研究领域:
肿瘤学
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医学影像学
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分子生物学
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DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2025
·
IF 9.5
Shuang Qiu,Yangming Zou,xiaoyu gu,Jiang Jing,Jun Sun,Haiqiao Wang,Bin Fei,Sheng Zhang
Solar power, as a clean and renewable energy source, holds tremendous potential for future energy systems. This study presented lightweight, flame-retardant, and durable polycarbonate (PC) encapsulation panels incorporated with a fluorescent agent to substitute the glass covers in photovoltaic (PV) modules. A novel fluorescent derivative (TPA-BPOD), synthesized from triphenylamine and phenyl phosphonic dichloride, was doped into PC at a concentration of 0.5 wt%. The resulting PC panel (0.7 mm thickness) exhibited visible-light transmittance comparable to pure PC while effectively converting ultraviolet (UV) light to visible wavelengths. When applied to silicon solar cells as a front encapsulant, the PC+0.5% TPA-BPOD panel increased the power conversion efficiency (PCE) by 3.5%. Furthermore, the PC panel (1.6 mm thickness) demonstrated superior flame retardancy, achieving a UL-94 V-0 rating and a limiting oxygen index (LOI) of 28.8%, along with significantly suppressed release of toxic gases during combustion. After 360 h of accelerated UV aging (500 W, 60 °C), the PC+0.5% TPA-BPOD panel retained better mechanical properties than the undoped control, highlighting its improved durability. By enabling lightweight, safe, and efficiency-boosting PV encapsulation, this strategy supports the development of next-generation solar technologies, particularly in building-integrated or vehicle-integrated photovoltaics and flexible solar applications.
研究领域:
材料科学
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高分子化学
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能源材料
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光伏技术
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功能材料
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产品关联
DOI
高影响因子
Soft Matter
·
2019
·Vol. 15
·期 17
·3588-3594
·
IF 3.399
Hua-Xiu Xu,Yun Tan,Di Wang,Xiong-Lei Wang,Wen-Li An,Ping-Ping Xu,Shimei Xu,Yu-Zhong Wang
Fluorescent hydrogels have recently attracted great attention for medical diagnostics, bioimaging and environmental monitoring. However, additional phosphors or fluorophores are always required to label the hydrogels, and they suffer from marker bleaching, signal drifts, or information misrepresentation. Here we report autofluorescence that universally exists in carbonyl-containing hydrogels without any traditional fluorophore. The fluorescence is successfully employed to self-monitor the gelation process since the fluorescence signal is closely related to the internal structural change of the gels. The crosslinked structure is beneficial to the fluorescence efficiency. Specifically, the fluorescence intensity is amplified with decreasing water content of the gels. The system realizes aggregation-induced emission in a water-deficient environment. The fluorescence is quenched by the addition of some specific metal ions, which can realize the successfully erasure and rewriting of information under visible light and ultraviolet light respectively. We believe that the spontaneous fluorescence of a gel provides the most reliable basis for the detection of a gel structure and opens new prospects in the application of hydrogels.
研究领域:
材料科学
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生物医学工程
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化学
·
环境监测
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产品关联
DOI
PubMed
高影响因子
MOLECULAR PHARMACEUTICS
·
2023
·
IF 4.9
Fulong Man,Yinqian Yang,Haisheng He,Jianping Qi,Wei Wu,Yi Lu
In vitro dissolution that predicts the in vivo performance of solid preparations is extremely important in formulation optimization. Fraction absorbed (Fa) has been used to screen in vitro dissolution protocols based on the idea of in vitro–in vivo correlation (IVIVC) but failed to increase the success rate due to the inaccuracy of the Fa. The essence of IVIVC is the correlation between in vitro dissolution and in vivo dissolution. We tried to establish in vitro dissolution protocol via similarity with in vivo dissolution using aripiprazole (APZ) as a model drug. Hybrid APZ crystals (APZ-HCs) were prepared by physically embedding aggregation-caused quenching (ACQ) fluorophores inside the lattice to measure the in vivo dissolution. The process did not change the physicochemical properties and crystallinity of APZ. The fluorophore illuminated APZ crystals but was quenched upon dissolution of APZ-HCs in aqueous media, enabling monitoring intact APZ-HCs in real-time. The good correlation between fluorescent quenching and dissolution of APZ-HCs justified reliable quantification of intact APZ crystals. The residual percentage of fluorescence intensity in rats treated by APZ-HCs was recorded with time, which was converted to in vivo dissolution by the difference from 100%. The in vivo dissolution was validated with the Fa. The in vitro dissolution profile of APZ was set up via a similarity factor larger than 50 in comparison with the in vivo dissolution. The study provides a novel idea and method to establish in vitro dissolution protocol.
研究领域:
药剂学
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药物递送系统
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药学
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DOI
PubMed
高影响因子
Frontiers in Chemistry
·
2021
·
IF 5.221
Chen Lujia,Chen Meijuan,Zhou Yuping,Ye Changsheng,Liu Ruiyuan
Preparation of near-infrared (NIR) emissive fluorophore for imaging-guided PDT (photodynamic therapy) has attracted enormous attention. Hence, NIR photosensitizers of two-photon (TP) fluorescent imaging and photodynamic therapy are highly desirable. In this contribution, a novel D-π-A structured NIR photosensitizer (TTRE) is synthesized. TTRE demonstrates near-infrared (NIR) emission, good biocompatibility, and superior photostability, which can act as TP fluorescent agent for clear visualization of cells and vascular in tissue with deep-tissue penetration. The PDT efficacy of TTRE as photosensitizer is exploited in vitro and in vivo. All these results confirm that TTRE would serve as potential platform for TP fluorescence imaging and imaging-guided photodynamic therapy.
研究领域:
生物医学工程
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分子影像
·
诊疗学
·
癌症研究
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Yizhong Shen,Yunlong Wei,Huanhuan Chen,Zeyu Wu,Yingwang Ye,De-Man Han
Reliable on-site monitoring of antibiotic residue is critical to establish the efficient pollution early-warning mechanism for ensuring food safety and environmental health . Herein, we reported the engineering of liposome-encapsulated aggregation-induced emission fluorogen into the portable smartphone for achieving the visual on-site detection of residual tetracycline (TC). Through nanoprecipitation, the aggregation-induced emission fluorogen (AIEgen) tetraphenylethene (TPE) was encapsulated into an amphiphilic phospholipid polymer, affording a scaffold to assemble Eu 3+ for forming Eu 3+ -functionalized liposome-based AIEgen (Eu 3+ @AIEgen) with bright blue fluorescence at ~456 nm. Upon assistance of citrate, TC was capable of triggering the remarkable fluorescence color change from bright blue (~456 nm) to pink owing to the new red fluorescence emission appeared at ~611 nm, thereby emerging a significant dual-emission for ratiometric response. As expected, an ingenious citrate-assisted Eu 3+ @AIEgen liposome-based smartphone was proposed to precisely on-site report the residual levels of TC in real sample among the linear range of 0.0961–10.0 μM. Furthermore, this portable sensor exhibited a high sensitivity attributable to the low detection limit of 28.83 nM together with a fast response kinetics of 2.0 min for TC, agreeing well with the demands of on-site assay. This study showed the promising potential for utilizing AIEgen liposome to develop a new category of portable sensors for the point-of-care detection of antibiotic residue in complicated food and environment-related matrixes, which might open a novel way to establish efficient pollution early-warning mechanism for safeguarding public health.
研究领域:
分析化学
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环境科学
·
食品安全
·
生物技术
·
公共卫生
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）