Carbon Letters
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2025
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IF 5.8
Hu Chaoshuai,Liu Yuanxin,Zhang Jian,Zhu Yaming,Yin Xitao,Zhao Xuefei
Using durian shell as a carbon source and triethanolamine as a nitrogen dopant, nitrogen-doped carbon dots (N-CDs) were prepared via the hydrothermal method. First, by exploring different reaction times, reaction temperatures, and carbon source/dopant ratios to synthesize nitrogen-doped carbon dots, it is concluded that the best process conditions are 200 ℃, reaction time being 15h, and the dopant addition amount being 2mL. Structure and characteristics of the synthesized CDs were analyzed using X-ray photoelectron spectroscopy, Fourier-transform infrared, fluorescence (FL), ultraviolet–visible absorption, and Raman spectra. The N-CDs showed blue FL with a quantum efficiency of 4.28%. The FL characteristics of the N-CDs were utilized for ion detection, which demonstrated that \({\text{MnO}}_{4}^{ - }\) and \({\text{Cr}}_{{2}} {\text{O}}_{7}^{2 - }\) ions caused distinct FL quenching through static quenching, while other ions had no significant quenching effect. The detection limits for \({\text{MnO}}_{4}^{ - }\) and \({\text{Cr}}_{{2}} {\text{O}}_{7}^{2 - }\) were 37.5 and 46.2 nM, respectively. The N-CDs were subsequently employed to detect these ions in actual water samples, producing satisfactory results. Therefore, the preparation of N-CDs using durian shell as raw material and its application in practical detection work have good application feedback, which not only provides a new way for the reuse of fruit and vegetable wastes but also provides a new detection means for environmental monitoring pollutants.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
MOLECULES
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2021
·Vol. 26
·期 19
·5965
·
IF 4.412
Xiaoxiao Chen,Yang Liu,Pu Li,Yichen Xing,Chaobiao Huang
A dual recognition system with a fluorescence quenching of quantum dots (QDs) and specific recognition of molecularly imprinted polymer (MIP) for the detection of chloramphenicol (CAP) was constructed. MIP@SiO2@QDs was prepared by reverse microemulsion method with 3-aminopropyltriethoxysilane (APTS), tetraethyl orthosilicate (TEOS) and QDs being used as the functional monomer, cross-linker and signal sources, respectively. MIP can specifically recognize CAP, and the fluorescence of QDs can be quenched by CAP due to the photo-induced electron transfer reaction between CAP and QDs. Thus, a method for the trace detection of CAP based on MIP@SiO2@QDs fluorescence quenching was established. The fluorescence quenching efficiency of MIP@SiO2@QDs displayed a desirable linear response to the concentration of CAP in the range of 1.00~4.00 × 102μmol × L−1, and the limit of detection was 0.35 μmol × L−1(3σ,n= 9). Importantly, MIP@SiO2@QDs presented good detection selectivity owing to specific recognition for CAP, and was successfully applied to quantify CAP in lake water with the recovery ranging 102.0~104.0%, suggesting this method has the promising potential for the on-site detection of CAP in environmental waters.Keywords:molecular imprinting;chloramphenicol;quantum dots;fluorescence quenching
研究领域:
分析化学
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环境科学
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DOI
PubMed
高影响因子
RSC Advances
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2017
·Vol. 7
·期 5
·2810-2816
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IF 3.108
Zhaogan Wang,Peng Long,Yiyu Feng,Chengqun Qin,Wei Feng
Hydroxyl functionalized carbon dots (H-CDs) were prepared by monoesterification of ethylene glycol. The H-CDs exhibit a narrow size distribution of 1–4 nm and enhanced photoluminescent (PL) intensity due to an increased amount of electron donor hydroxyl groups. According to fluorescence spectra, the H-CDs exhibit a high sensitivity to Fe3+ with a detection limit of 2.56 nM, which is superior to the detection limit of CDs (7.4 μM). The quenching fluorescence is primarily controlled by the formation of a chelate compound based on the complexation between Fe3+ and the hydroxyl on the surface of the H-CDs. Furthermore, we demonstrate that paper impregnated with H-CDs exhibits a high sensitivity to Fe3+ by fluorescence quenching. In the future, the modified CDs can be developed for high sensitivity fluorescent probes by optimizing the chemical structures and microstructures.
研究领域:
材料科学
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分析化学
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
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2020
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IF 6.182
Saijiao Yang,Meiying Liu,Fengjie Deng,Liucheng Mao,Yiyang Yuan,Hongye Huang,Junyu Chen,Liangji Liu,Xiaoyong Zhang,Yen Wei
Highly sensitive and selective detection of specific DNA or metal ions based on sensor platform of dye-labeled single-stranded DNA (named as ssDNA) and functional materials has attracted great research interest over the past few decades. Herein, we reported for the first time that polydopamine (PDA) modified SiO 2 nanoparticles (PDA- co -SiO 2 NPs) could be severed as effective fluorescent quenchers for fabrication of fluorescent DNA sensor systems for detection of functional nuclear acids and Ag + . To prepare PDA- co -SiO 2 NPs, we just need mix SiO 2 nanoparticles with dopamine in aqueous solution under rather mild experimental conditions. These PDA- co -SiO 2 NPs-based sensor systems possess excellent sensitivity and selectivity, fast response for detection of target ssDNA and Ag + based on different fluorescence quenching effect of PDA- co -SiO 2 NPs towards ssDNA and dsDNA. Furthermore, the high fluorescence quenching ability of PDA- co -SiO 2 NPs allows quantitative detection of target ssDNA with a low detection limit of 1 nM. More importantly, this method would also be easily extended for preparation of many other PDA-based materials for fabrication of fluorescent DNA sensors owing to the universal attachment of PDA with various materials and surfaces. Therefore, this work will open up a new direction for analytical detection of PDA-based functional materials.
研究领域:
纳米技术
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分析化学
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材料科学
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生物技术
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产品关联
DOI
高影响因子
KEY ENGINEERING MATERIALS
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2014
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IF 0
Xin Feng Zhu,Jue Feng,Jun Wu Zhu,Bin Li,Qin Xu
Simultaneous determination of Pb2+ and Co2+ without separation has been successfully achieved by a bicolor quantumn dots mixture. This method takes advantage of the different degrees of the fluorescence quenching effects of Pb2+ and Co2+ to the bio-color quantum dots. Chemometrical approaches were applied to assist the discrimination and detection process. The construction of the multivariate calibration models, based on partial least squares (PLS), orthogonal projections to latent structures least squares (O-PLS) and kenel based orthogonal projections to latent structures (K-OPLS), allowed the simultaneous determination of Pb2+ (in the concentration range of 0-120 mM) and Co2+ (0-300 mM). The optimal number of factors in PLS and the optimal number of orthogonal components in O-PLS and K-OPLS were carefully selected. A comparison of prediction performances between these results was performed by relative prediction errors, square of the correlation coefficient and root mean squares error of prediction.
研究领域:
分析化学
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生物医学工程
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DOI
Analytical Methods
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2025
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IF 2.6
Qian Sun,Lu Ren,Jing Liu,Zhaoyun Yang,Dawei Zhang,Shuangbao Li
A Schiff base fluorescent probe, HTT, based on a sulfonylhydrazone structure was designed and synthesized for the sensitive and selective detection of Cu2+. The probe HTT exhibits good anti-interference performance toward Cu2+ in the presence of a variety of metal ions. After the addition of Cu2+, it can quickly respond within 40 seconds, and the fluorescence detection limit is 1.10 nM. The coordination ratio of probe HTT and Cu2+ is 2 : 1, and the coordination reaction between CN, SO and Cu2+ limits the formation of hydrogen bonds between the hydroxyl group and CN, disrupting the spatial coplanar effect of the probe molecule and thereby inducing fluorescence quenching. The probes can be recovered and reused using EDTA for the detection of Cu2+. The probe was also applied to the successful monitoring of Cu2+ in living cells and real water samples.
研究领域:
分析化学
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生物化学
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细胞生物学
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产品关联
DOI
PubMed
高影响因子
Processes
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2021
·Vol. 9
·期 1
·170
·
IF 2.847
Xiupei Yang,Fangming Tian,Shaohua Wen,Hua Xu,Lin Zhang,Jie Zeng
A cost-effective and environmentally friendly method was formulated for rapid dopamine (DA) detection that was based on the fluorescence (FL) quenching of carbon quantum dots (C-dots). Upon adding DA to the C-dots’ solution, we noticed a regular reduction in their fluorescence intensity. The effects of pH, amount of C-dots, reaction temperature and time on the determination of DA were investigated. Under the optimized experimental conditions, trace amounts of DA could be analyzed. Furthermore, dopamine hydrochloride injection and human urine samples with and without spiked DA were analyzed using the developed sensing system. The procedure was validated following the guidelines of the European Medicines Agency (EMA) in terms of the following: calibration range (0.3–100 μM), linearity (R2= 0.9991), limit of detection (LOD) (93 nM). Recoveries of dopamine with spiked samples at three different levels were between 95.0 and 105.9%, and the relative standard deviations (RSDs) were within 2.68% (n = 6). This method is simple and suitable for the determination of dopamine in pharmaceuticals and human urine for clinical application. Compared with previous reports, the proposed method offers great advantages including ease of C-dot sensor preparation (one-pot synthesis), environmentally friendly sample preparation by using either water or phosphate buffer solution only, a short response time and selectivity.Keywords:carbon quantum dots;dopamine;fluorescence quenching;yet photochemical probe
研究领域:
分析化学
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医学检测
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DOI
高影响因子
TALANTA
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2019
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IF 4.916
Shaomei Xu,Songtian Che,Pinyi Ma,Fangmei Zhang,Longbin Xu,Xin Liu,Xinghua Wang,Daqian Song,Ying Sun
Typically, sialic acids (SA) with a nine-carbon backbone are found at the glycan chain termini on the cell membranes, which play crucial roles in various physiological and pathological processes. The expression level of SA in the blood serum has been reported to correlate with various disease states among cancer. In this study, a novel approach for preparing fluorescent boronic-acid-modified carbon dots (C-dots) for the detection of SA was developed. The functionalized C-dots were synthesized by a facile, one-step hydrothermal method using 3-pyridineboronic acid as the sole carbon source. The added SA selectively recognized the C-dots, leading to the fluorescence quenching of the C-dots in a linear range of 80–4000 μM with a detection limit of 54 μM. The as-developed boronic-acid nanoprobe was successfully applied for the detection of SA in human serum samples with satisfactory results. In addition, this method afforded results within 4 min. Compared to other methods, this new proposed approach was simpler and exhibited excellent sensitivity and selectivity, demonstrating immense potential as an alternative for SA detection.
研究领域:
生物化学
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医学诊断
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纳米材料科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
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2021
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IF 6.064
Seyed Mostafa Jafari,Saeed Masoum,Seyed Ali Hosseini Tafreshi
In the present work, Chlorella vulgaris , a well-known microalga was used as a carbonic precursor, to synthesis the water-soluble carbon dots (CDs) via hydrothermal method. To improve the properties, acidic carbon dots (ACDs) were also synthesized via ultrasoncation of microalgal biomass after acidic hydrolysis (using diluted acidic solution). The aqueous solution of ACDs was used as a sensor for glucose determination based on glucose oxidase enzyme (GOx) reaction and fluorescence quenching of ACDs in the presence of Fe 3+ ions under the optimized conditions. The linear range of glucose in the blood serum was measured from a range of 5 µM to 500 µM with a limit of detection (LOD) 2.84 µM. Additionally, the hydrogen peroxide, as the conventional reactive oxygen species (ROS) was determined based on the Fenton reaction. The linear range of H 2 O 2 was obtained from 10 µM to 200 µM with LOD of 975 nM. In all of these applications, fluorescence quenching of ACDs was followed according to photo-induced electron transfer (PET) mechanism in the presence of generated Fe 3+ ions by Fenton reaction.
研究领域:
生物传感
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医学检测
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材料科学
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2014
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IF 3.84
Guang-Li Wang,Xue-Lian Hu,Xiu-Ming Wu,Zai-Jun Li
In this paper, a novel and sensitive assembled quantum dots (QDs)–bienzyme (glucose oxidase (GOD) and horseradish peroxidise (HRP)) hybrid system was designed for the direct determination of glucose. Using o-phenylenediamine (OPD) or 3,3′-diaminobenzidine (DAB) as substrate of HRP, whose corresponding oxidation product (oxOPD or oxDAB) effectively quenched the fluorescence of thioglycollic acid (TGA)-capped CdS QDs. The fluorescence quenching of the CdS QDs was proportional to the concentration of glucose and a detection limit of 0.1 μmol/L (or 20 nmol/L) was achieved under the optimum conditions when using OPD (or DAB) as the substrate of HRP. The sensing system was also applied to the determination of glucose in human serum with satisfactory results without any need for complicated sample pretreatments. Other sugars such as fructose, sucrose and lactose hardly interfered on the detection of glucose. The developed method manifested several advantages of high sensitivity, short analysis time, low cost and easy of operation. Moreover, it had great potential in the direct detection of real samples in clinical diagnostics of various diseases.
研究领域:
生物化学
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医学诊断
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2025
·
IF 6.1
Mengting Liu,Zuncai Gu,Lu Qian,Kawtar Ettayri,Tao Deng,Chenhao Zhang,Jing Qian,Xingyi Huang,Chengquan Wang
Oxytetracycline (OTC), a broad class of antibacterial medication, has been widely utilized in poultry husbandry and fish farming. However, the presence of OTC residues in the food has become a matter of great concern. These residues have the potential to induce the emergence and spread of bacterial resistance, which can have far-reaching consequences for public health. In this work, we focused on the comparison of the quenching efficiency of UiO-66 and its amino group-modified counterpart UiO-66-NH 2 , towards the fluorescence of nitrogen-doped graphene quantum dots (NGQDs) labeled aptamer (NGQDs-apt). It was found that UiO-66-NH 2 demonstrated a more potent fluorescence quenching ability towards NGQDs-apt, as high as 98.8 %, compared to 69.7 % for UiO-66 without amino functionalization. This enhanced performance is attributed to the improved interaction between the amino groups on UiO-66-NH 2 and the NGQDs-apt, facilitating more effective electron transfer. Consequently, UiO-66-NH 2 was selected as the optimal quencher for the development of a highly sensitive aptasensor. This aptasensor demonstrates a quantitative detection range for OTC spanning from 0.001 to 200 μM with an exceptionally low detection limit of 0.25 nM, showing simplicity, accuracy, stability and great potential for antibiotic residue detection in food samples. This work addresses the urgent need to develop reliable methods for detecting OTC residues in food due to the potential of OTC to trigger bacterial resistance, which is crucial for food safety and public health.
研究领域:
生物传感
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食品安全
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2019
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IF 3.206
Linli Hou,Yonghai Song,Yingjie Xiao,Rong Wu,Li Wang
Fluorescent metal-organic frameworks (MOFs) have attracted wide attention in fluorescence detection. Herein, a novel sensing platform for highly selective and sensitive detection of Fe 3+ in aqueous solution was proposed based on 2,5-dihydroxyterephthalic acid (DOBDC)-Zn 2+ MOFs (ZnMOF-74). The as-prepared ZnMOF-74 exhibited uniform clavicorn nanostructures and high day-to-day stability in acidic aqueous solution (pH 4.0). Because of the special response of phenolic hydroxyl groups of DOBDC with Fe 3+ , the cation exchange between Fe 3+ and Zn 2+ occurred, which caused collapse of the skeleton and formed a blue weak-fluorescent iron(III)-phenol salt complex (Fe-DOBDC), which led to the effective fluorescence quenching of ZnMOF-74. ZnMOF-74 was used as a probe for detection of Fe 3+ under relatively acidic condition with a good linear range of 0.1–100 μM and a low detection limit of 40 nM. The fluorescence probe was also applied to determine Fe 3+ in real river water and human serum with good recovery and accuracy. This work provided a good Fe 3+ sensor based on ZnMOF-74 due to high affinity between phenolic hydroxyl group and Fe 3+ .
研究领域:
材料科学
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分析化学
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环境科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）