CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2023
·
IF 3.8
Xiaolin Pan,Mengyuan Gao,Yun Wang,Yanping He,Tian Si,Yanlin Sun
Drug-loaded microspheres are significant for the development of modern pharmaceutical products. It is well known that the taken of aspirin for long-term increases the risk of serious gastrointestinal complications, therefore a controllable delivery of aspirin is of importance to lighten those side effects. In this work, poly(lactic acid) (PLA) was chosen as the carrier to prepare PLA-aspirin microspheres by using the traditional and the improved solvent evaporation methods. It was found that no matter which experimental condition was, the encapsulation efficiency of aspirin was higher by using the improved method than that of the traditional method. Specifically, when the concentration of polyvinyl alcohol = 1% (mass), the polymer concentration = 1:20, the oil/water rate = 1:2.5, PLA-aspirin microspheres were obtained via the improved method with a high yield of 82.83% (mass) and an encapsulation efficiency of 44.09%. PLA-aspirin microspheres were then prepared continuously using the improved method, which further enhanced the encapsulation efficiency to 54.56%. Approximate 85% aspirin released from microspheres within 7 days. Obvious degradation which was represented by reduction on hardness was observed by soaking microspheres in PBS for 60 days. This work is of interest because it provides a continuous route to prepare PLA-aspirin microspheres continuously with a high drug encapsulation efficiency.
研究领域:
药剂学
·
生物医学工程
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产品关联
DOI
高影响因子
CHEMISTRY LETTERS
·
2011
·Vol. 40
·期 5
·544-545
·
IF 1.401
Xiao Yan,Li Yan,Zhang Meng,Wang Feng-Xia,Pan Ge-Bo
Copper–phthalocyanine (CuPc) nanorods were prepared on a Si substrate by a solvent evaporation method. The results of XRD indicate that the CuPc nanorods were β-phase single crystals and grown along the [010] direction. The diameters of CuPc nanorods depend on the solution concentration, and the formation of CuPc nanorods is insensitive to the solvents and substrates. This implies that the growth of CuPc nanorods is dominated by the intrinsic π–π stacking between Pc rings. In addition, a p–n junction was formed between CuPc nanorod and Si substrate.
研究领域:
材料科学
·
纳米技术
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2025
·Vol. 27
·期 18
·2920-2930
·
IF 2.6
Haoxin Hu,Shizhao Ren,Feiting Gan,Rongrong Xue,Fenghua Chen
Hypoxanthine is an important component in guanine biominerals, and its polymorphs and morphology controls are rarely reported. In this work, three polymorphs of hypoxanthine were obtained by a solvent evaporation method: form I (triclinic) from an aqueous solution, form II (monoclinic) from an ethanol solution, and form III (a newly proposed polymorph but not observed first) from an ammonia solution. Solubility measurements in water and ethanol indicated that the stability order of the three polymorphs of hypoxanthine was form I > form III > form II. The Raman, IR and 13C ss-NMR spectra indicated that the crystal structures of forms I and III were similar but different from that of form II. The formation of form II was related to the hypoxanthine assemblies in ethanol, as demonstrated by UV spectroscopy. The PXRD patterns and SEM images showed that the three polymorphs had different growth behaviors, as revealed by comparing the hydrogen-bonding planes and π–π stacking modes. Form I had a flat hydrogen-bonding plane with non-vertical π–π stacking, benefitting v∥hydrogen-bonding, while form II had a wavy hydrogen-bonding plane with vertical π–π stacking, benefitting from v∥π–π stacking. The polymorph and morphology controls of hypoxanthine can extend the understanding of the principles of organic biomineralization based on guanine biominerals.
研究领域:
化学
·
生物矿化
·
材料科学
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产品关联
DOI
高影响因子
CRYSTENGCOMM
·
2012
·Vol. 14
·期 6
·1933-1935
·
IF 3.842
Yan Xiao,Meng Zhang,Feng-Xia Wang,Ge-Bo Pan
Hierarchical flower-shaped NPB architectures are prepared via a facile solvent evaporation method and investigated by means of SEM, TEM, FT-IR, and XRD. The results indicate that each NPB flower is composed of a number of randomly oriented nanoflakes, which are single crystals and connect with each other. Furthermore, time-dependent experiments reveal that the NPB flowers are formed via a heterogeneous nucleation, coupled with “Ostwald ripening”. The densely packed films of NPB flowers, which can withstand extreme conditions, e.g., high temperature, strong acid, and strong alkali possess a durable water-repellent property.
研究领域:
材料科学
·
表面化学
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DOI
高影响因子
COMBUSTION AND FLAME
·
2023
·
IF 4.4
Zhenhui Liu,Rongjie Yang,Fei Xiao
Because of the existence of an oxide layer on the surface of micron aluminum (μAl) powder, it is difficult to ignite. In order to improve μAl ignition, Al particles were coated with bismuth citrate (Bi(cit)) by a solvent evaporation method. The morphology of Al-Bi(cit) was observed by scanning electron microscope (SEM) showed that Bi(cit) was evenly distributed on the surface of Al particles. The ignition temperature was reduced and ignition delay time at different temperatures of the Al-Bi(cit) were tested in a transparent tube furnace. With the increase of Bi(cit) content, the ignition temperature and ignition delay time shortened, and the combustion flame captured by the high-speed camera was more bright. The test results showed that Al-20 wt% Bi(cit) has a low ignition temperature of 479 °C, and the ignition delay time at 450 °C is only 7 s. The thermal behavior of Al-Bi(cit) was studied by thermogravimetric analysis (TG-DSC). Combined with the characterization results of the products at different heating temperatures, the combustion mechanism was proposed and proved.
研究领域:
材料科学
·
燃烧化学
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产品关联
DOI
高影响因子
JOURNAL OF FOOD SCIENCE
·
2022
·Vol. 87
·期 3
·998-1008
·
IF 3.693
Rongxi Fang,Hongshan Liang,Jing Li,Yijie Chen,Xiaogang Luo,Yan Li,Bin Li,Shilin Liu
Astaxanthin (AXT) is widely used in the food, drug, and cosmetics fields, but its applications are extremely limited by its intrinsic properties. Herein, a novel encapsulation system had been performed to fabricate AXT-loaded microcapsules through emulsion solvent evaporation and spray-dried methodologies. The influence of polylactic acid (PLA) concentrations on the characteristics of AXT-loaded dispersions and resultant microcapsules were investigated. The results showed that the sizes and zeta potentials of dispersions and microcapsules increased with increasing PLA content (9.8 to 24.6 wt%). The encapsulation efficiency (EE) of the microcapsules increased with increasing PLA concentration up to 21.4 wt%. The moisture content values, flowability, and bulk density of the obtained microcapsules decreased with increasing PLA content (9.8 to 24.6 wt%). Furthermore, the cell culture experiment indicated that the obtained microcapsules had no cytotoxicity and possessed excellent antioxidant activity. This work provides a new strategy for fabricating AXT-enriched microcapsules and expands their application in nutritional products. Practical Application This work fabricated a novel encapsulation system for AXT through emulsion solvent evaporation and spray drying methodologies. The obtained AXT-loaded microcapsules possessed great physical stability and could expand potential applications of AXT.
研究领域:
食品科学
·
药物学
·
化妆品科学
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产品关联
DOI
PubMed
高影响因子
MATERIALS CHARACTERIZATION
·
2023
·
IF 4.7
Hui Zhu,Bo Liu,Ling Wu,Ye Cong,Zhijun Dong,Jianguang Guo,Baoliu Li,Xuanke Li
The in-suit synthesis of SiC nanowires (SiCNWs) on carbon fibers (CFs) to produce SiC@C composites is pivotal due to their broad applications. However, it's challenging because most CFs have a microstructure unsuitable for SiCNWs nucleation. In this study, we introduced a series of carbide coatings on CFs to facilitate the growth of SiCNWs through a thermal evaporation process. It was observed that carbide coatings on CFs significantly enhance the nucleation of SiC, enabling the efficient production of SiCNWs@CF. These SiCNWs can grow directly on the carbide-coated CFs through heteroepitaxial nucleation. Carbide coatings with a cubic phase structure and a crystalline size of less than 50 nm are vital for SiCNWs formation. This carbides coating approach is beneficial not only for carbon materials but also holds potential for numerous other matrices.
研究领域:
材料科学
·
纳米技术
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产品关联
DOI
高影响因子
MATERIALS LETTERS
·
2024
·
IF 2.7
Ying Chen,Minghao Li,Jing Huang,Hui Zeng,Linhua Xu,Jing Su
This paper presents the growth of large-sized CsCu(Br, Cl) 3 crystals using the aqueous solution evaporation method. The structure and the components of the crystals were analyzed. It was found that CsCuBr 3 is a direct bandgap material, while CsCuCl 3 is an indirect bandgap material, and the band gap of CsCu(Br, Cl) 3 halides can be adjusted in the range of 2.63–3.63 eV (PBE) by changing the ratio of Br - /Cl - . Besides CsCuCl 3, which has an absorption valley at 654 nm, the other CsCu(Br, Cl) 3 crystals show high absorption in the range of 200–1000 nm. Under UV excitation, the PL spectra show that CsCu(Br, Cl) 3 crystals exhibit red and blue emission.
研究领域:
材料科学
·
光学
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DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2021
·
IF 5.645
Miao Wang,Dongjie Yang,Qinghe Xu,Peishi Li,Conghua Yi,Yong Qian,Xueqing Qiu
In this study, we establish a novel highly efficient preparation process to prepare homogeneous and size controllable pH-responsive lignin nanosphere (LN). Orthogonal experiments have been performed to investigate the effects of the factors (bath temperature, lignin concentration, starting volume, cooling temperature) on the effective diameters (ED) and polydispersity index (PDI) of LN. The fast vacuum evaporation process could also encapsulate drugs in the one-pot process, with the solvent acetone recycled simultaneously. The drug release based on pH-responsive have been investigated. As a result, homogenous LN with targeted size (within 100 ∼ 400 nm) had been obtained under the preparation conditions suggested by the established Models. The matrix entrapment efficiency of LN was 47 %. The lignin encapsulating Ibuprofen nanospheres showed excellent pH-responsive release. It had just 18 % released at pH 1.2, while over 90 % at pH7.5 for 2−6 h. This study introduced a highly efficient way to prepare lignin nanospheres and a new strategy to prepare pH-responsive drugs.
研究领域:
材料科学
·
药学
·
纳米技术
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DOI
高影响因子
CATALYSIS SURVEYS FROM ASIA
·
2021
·Vol. 25
·期 3
·312-323
·
IF 3.106
Song Qi,Ran Rui,Li Dongyang,Zhao Baohuai,Weng Duan
Mesoporous silica was used in conjunction with the ammonia evaporation method to prepare highly dispersed Ni catalysts for the dry reforming of methane (DRM). The effect of Ni dispersion on the catalytic performance was investigated by applying different Ni loadings. The pore structure, morphology, Ni dispersion, catalytic activity for DRM as well as the coke resistance were investigated. During the reaction at a relatively low temperature of 600 °C, all the three catalysts exhibited high stability in CH 4 and CO 2 conversion and excellent coke resistance, in comparison to Ni/SiO 2 catalyst prepared by the incipient wetness method. Among them, 10% Ni–SiO 2 exhibited the best catalytic performance with the maximum steady conversions of 62% and 69% for CH 4 and CO 2 at 600 °C, which was beneficial from its optimal Ni content and the presence of highly-dispersed metal nanoparticles confined in the mesopores.
研究领域:
材料科学
·
催化化学
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产品关联
DOI
高影响因子
SOLAR ENERGY
·
2019
·
IF 4.674
Guoxing Pan,Dongxiao Wang,Shoushuai Gao,Peng Gao,Qiang Sun,Xingjiang Liu,Zhiqiang Zhou,Yun Sun,Yi Zhang
Sb 2 S 3 thin film solar cells have been attracting much attention because of its excellent the photoelectric properties. By now, all the works on Sb 2 S 3 solar cell were focused on the Sb 2 S 3 thin film solar cells with sensitized structure or superstrate structure. However, Sb 2 S 3 solar cell with substrate structure was rarely reported. The substrate structure of the Sb 2 S 3 solar cell has unique advantages in device interface optimization, film growth, and application on flexible devices, and so on. The study of the substrate structure has great significance for improving the efficiency of the device and expanding its application range. In this work, Sb 2 S 3 thin films were deposited on Mo-coated glass substrate by the rapid thermal evaporation (RTE) method. The Sb 2 S 3 thin film quality is improved by combining adjusting the substrate temperature and evaporation time. Finally, a 1.75% efficient Sb 2 S 3 thin film solar cells with the substrate configuration of SLG/Mo/Sb 2 S 3 /CdS/i-ZO/AZO/Ni:Al was fabricated. Experimental and SCAPS simulation results show that deep level defects in the absorber layer and interface of the absorber layer and the buffer layer are the main reason for limiting the efficiency of devices.
研究领域:
材料科学
·
光伏技术
✓ 已验证
产品关联
DOI
高影响因子
Solar RRL
·
2019
·Vol. 3
·期 12
·1900305
·
IF 0
Muhammad Ishaq,Hui Deng,Umar Farooq,Huan Zhang,Xiaokun Yang,Usman Ali Shah,Haisheng Song
Sb 2 S 3 being a light-absorbing material is used for photovoltaic (PV) application due to its superior stability and progressive power conversion efficiency (PCE) benefiting from its low cost, less toxic, earth-abundant, and facile nature. Due to the difficulty in efficient doping for such 1D structure, the performance of as-fabricated thin-film solar cells is limited by high resistivity and hole extraction barrier. Herein, a coevaporation scheme is introduced for copper-doped Sb 2 S 3 by rapid thermal evaporation (RTE). The Cu-doped Sb 2 S 3 thin film discloses the enhanced crystallinity with a grain diameter greater than 1 µm and conductivity along with improved carrier concentration. At the same time, the deep valance band obtains a minor upshift, favoring the hole extraction at back contact. Consequently, all the PV parameters are enhanced leading to the PCE boosting from 4.18% to 4.61%. Herein, a facile doping technique is demonstrated to improve its performance without any modification of the present RTE method.
研究领域:
材料科学
·
光伏技术
✓ 已验证
产品关联
DOI
危险品化学品经营许可证（带存储）