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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY · 2019 · IF 4.029

On the luminance saturation of phosphor-in-glass (PiG) films for blue-laser-driven white lighting: Effects of the phosphor content and the film thickness

Ran Wei,Le Wang,Peng Zheng,HuaTao Zeng,GuiMing Pan,Hong Zhang,Pei Liang,TianLiang Zhou,RongJun Xie

To investigate the luminance saturation in high-power blue-laser-driven solid state lighting, the Y 3 Al 5 O 12 : Ce (YAG)-based PiG films was co-fired with a high thermally conductive sapphire substrate. When the PtG ratio or the thickness of the PiG film increases, the luminance saturation becomes worse and both of the luminous flux and luminous efficacy decrease. With an additional sapphire substrate coated with an anti-reflection layer on one side and a blue-pass filter on another side attached to the PiG film, the film shows an improvement in luminous flux and efficacy, and produces the white light with a luminous flux of 1709 lm, a luminous efficacy of 211 lm W −1 and a correlated color temperature of 6602 K under the maximum (10.3 W mm −2 ) blue laser light excitation. It indicates that the PiG film could be applied in high power laser-driven solid state lighting when its microstructure is carefully tailored.

研究领域: 光学 · 材料科学
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ADVANCED MATERIALS · 2024 ·Vol. 36 ·期 40 ·2405290 · IF 27.4

Blue Laser Triggered Hemostatic Peptide Hydrogel for Gastrointestinal Bleeding Treatment

Qiang Luo,Jie Luo,Zhaohui Luan,Kaige Xu,Lixing Tian,Kebin Zhang,Xue Peng,Mengxue Yuan,Chuanhao Zheng,Zhenzhen Shu,Yuchen Zhang,Shali Tan,Ruijue Dan,Kibret Mequanint,Chaoqiang Fan,Malcolm Xing,Shiming Yang

In an emergency, nonvariceal upper gastrointestinal bleeding (NVUGIB), endoscopic hemostasis is considered the gold standard intervention. However, current endoscopic hemostasis is very challenging to manage bleeding in large-diameter or deep lesions highly prone to rebleeding risk. Herein, a novel hemostatic peptide hydrogel (HPH) is reported, consisting of a self-assembly peptide sequence CFLIVIGSIIVPGDGVPGDG (PFV) and gelatin methacryloyl (GelMA), which can be triggered by blue laser endoscopy (BLE) for nonvariceal upper gastrointestinal bleeding treatment without recurring bleeding concerns. Upon contact with GelMA solution, PFV immediately fibrillates into β-sheet nanofiber and solvent-induced self-assembly to form HPH gel. HPH nanofiber networks induced ultrafast coagulation by enveloping blood cells and activating platelets and coagulation factors even to the blood with coagulopathy. Besides its remarkable hemostatic performance in artery and liver injury models, HPH achieves instant bleeding management in porcine NVUGIB models within 60 s by preventing the rebleeding risk. This work demonstrates an extraordinary hemostatic agent for NVUGIB intervention by BLE for the first time, broadening potential application scenarios, including patients with coagulopathy and promising clinical prospects.

CAS / MDL:
研究领域: 生物医学工程 · 材料科学 · 消化内科
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OPTICS EXPRESS · 2019 ·Vol. 27 ·期 17 ·23981-23995 · IF 3.561

Core-shell Au@Ag nanodendrites supported on TiO2 nanowires for blue laser beam-excited SERS-based pH sensing

Anxin Jiao,Hua Zhang,Linlin Xu,Yue Tian,Xiangdong Liu,Ming Chen,Feng Chen

The blue laser beam-excited surface-enhanced Raman scattering (SERS)-based pH sensing holds great promise for avoiding undesired thermal heating effect on some special temperature-vulnerable molecules, as compared to the vast majority studies by exciting in the red or near-infrared (NIR). Herein, we report an ingenious approach to support core-shell Au@Ag nanodendrites (NDs) on TiO2 nanowires, which can possess enhanced SERS activity under 473 nm laser excitation, owing to the improved charge-transfer effect on modified TiO2 support by inserting plasmonic Au@Ag. By using pH-indicating 4-mercaptobenzoic acid (4-MBA), the obtained TiO2/Au@Ag NDs can not only exhibit high sensitive linear-responses of pH changes ranging from pH 4.0 to 9.0 in different solutions (deionized water, NaCl, CaCl2, and MgCl2) but also provide excellent temperature stability under 4°C, 25°C and 37°C temperatures as well as good time stability after storage for 10 days. The established SERS-pH sensing by using shorter wavelength laser excitation is highly desirable for understanding physiological process in temperature-vulnerable microenvironment.

研究领域: 材料科学 · 分析化学 · 纳米技术 · 光学
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2024 · IF 7.7

Curcumin-loaded mesoporous polydopamine nanoparticles modified by quaternized chitosan against bacterial infection through synergistic effect

Xiao Han,Weijia Gao,Zhe Zhou,Yongli Li,Duo Sun,Heyi Gong,Mengyuan Jiang,Yulu Gan,Xin Fang,Yuanzheng Qi,Junjie Jiao,Jinghui Zhao

Clinically, open wounds caused by accidental trauma and surgical lesion resection are easily infected by external bacteria, hindering wound healing. Antibacterial photodynamic therapy has become a promising treatment strategy for wound infection. In this study, a novel antibacterial nanocomposite material (QMC NPs) was synthesized by curcumin, quaternized chitosan and mesoporous polydopamine nanoparticles. The results showed that 150 μg/mL QMC NPs had good biocompatibility and exerted excellent antibacterial activity against Staphylococcus aureus and Escherichia coli after blue laser irradiation (450 nm, 1 W/cm 2 ). In vivo, QMC NPs effectively treated bacterial infection and accelerated the healing of infected wounds in mice.

研究领域: 纳米技术 · 生物医学工程 · 药学 · 微生物学 · 伤口愈合
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ADVANCED FUNCTIONAL MATERIALS · 2025 · IF 19

Achieving Ultra-Brightness Green Light Source with Electro-optical Conversion Efficiency up to 26.3% for Underwater Wireless Optical Communication

Yuqin Guo,Guojuan Wang,Linrong Qiu,Chengwu Hong,Shuxing Li,Rong-Jun Xie

Using blue lasers to excite green-emitting phosphors offers a compelling solution to address the “green gap” issue, providing a high-brightness green light source for underwater wireless optical communication (UWOC). However, current green-emitting phosphors show poor light conversion efficiencies or inadequate luminance saturation thresholds, impeding the development of brighter green light sources. Herein, the porous Lu 3 Al 5 O 12 :Ce phosphor ceramics are designed, which shows no change in quantum efficiency (82%) even after 6000 h of extended aging. This design results in a substantial improvement in light conversion efficiency (61.6%), luminous efficacy (286 lm·W⁻¹), and an exceptional luminance saturation threshold of 33 W·mm⁻ 2 , culminating in a maximum green light flux of 4720 lm. Moreover, the high-directionality green light source device has been fabricated that achieves an illuminance of 6081 lx at a distance of 10 meters (15.0 W blue laser irradiation) with the electro-optical conversion efficiency up to 26.3%, much higher than that using green laser directly (usually <20%). This setup enables long-range underwater transmission of 65.3 meters with a peak data rate of 3.45 MHz, opening up new avenues for innovative advancements in UWOC technology.

研究领域: 光学通信 · 光子学 · 材料科学 · 固态照明 · 水下技术 · 激光技术 · 通信工程
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