BIOMACROMOLECULES
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2024
·
IF 5.5
Min Cui,Shuwei Liu,Xuelai Xie,Jinhong Yang,Tianyuan Wang,Yuyang Jiao,Min Lin,Kunyan Sui
Material reinforcement commonly exists in a contradiction between strength and toughness enhancement. Herein, a reinforced strategy through self-assembly is proposed for alginate fibers. Sodium alginate (SA) microstructures with regulated secondary structures are assembled in acidic and ethanol as reinforcing units for alginate fibers. Acidity increases the flexibility of the helix and contributes to enhanced extendibility. Ethanol is responsible for formation of a stiff β-sheet, which enhances the modulus and strength. The structurally engineered SA assembly exhibits robust mechanical compatibility, and thus reinforced alginate fibers possess an improved tensile strength of 2.1 times, a prolonged elongation of 1.5 times, and an enhanced toughness of 3.0 times compared with SA fibers without reinforcement. The reinforcement through self-assembly provides an understanding of strengthening and toughening mechanism based on secondary structures. Due to a similar modulus with bones, reinforced alginate fibers exhibit good efficacy in accelerating bone regeneration in vivo.
研究领域:
材料科学
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生物材料
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2024
·
IF 4.1
Lei Wu,Menghan Liu,Yuting Chen,Ming Li,Tingting Yin,Cong Ma,Wei Fan
UF is widely used as a wastewater treatment and recycling technology. However, membrane fouling is still an important factor affecting the wide application. In this study, APIm with positive amino group was adsorbed to the surface of the carboxylated polyacrylonitrile (PAN) membrane by electrostatic force to reduce the fouling of sodium alginate (SA) caused by Ca 2+ . The results show that 1 v/v% APIm was selected as the optimal dosage, accompanied by the highest water flux of 330.5 L·m -2 h −1 bar −1 and bovine serum albumin (BSA) rejection rate of 91.0 %. When the concentration of Ca 2+ was increased to 10 mM, the Ca 2+ catch amount increased to 48.25 mg/cm 2 . The main anti-fouling mechanism was that APIm captured a certain amount of Ca 2+ in situ, destroyed the complex structure of sodium alginate (SA) and Ca 2+ . Then the fouling layer was easy to be removed by physical cleaning. At the concentration of 10 mM Ca 2+ , the membrane flux recovery rate of 1 v/v% APIm membrane was increased to 80.1 %. This study demonstrates a fouling control strategy for in-situ removal of Ca 2+ bound SA fouling, providing a new approach for the future development of UF membrane.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Kaiwen Xie,Xiang Xu,Chengcheng Gao,Zhenjiong Wang,Linghan Meng,Xiao Feng,Xiaozhi Tang
The regulatory effects of different mannuronate/guluronate ratios in sodium alginate (SA) and calcium ion (Ca 2+ ) concentrations on the structure and properties of starch-SA interpenetrating polymer network (IPN)-enhanced extruded buckwheat noodles were investigated. The thermal stability of buckwheat noodles was improved by increasing the G block proportion, and 1% Ca 2+ concentration led to the highest thermal stability. With increasing G proportion and Ca 2+ concentration, cooking loss and elongation at break of extruded noodles gradually decreased. The cooking time initially decreased and then increased. Noodle hardness, chewiness, and breaking strength significantly increased. In vitro starch digestion showed that when the SA M/G ratio was 1:2 and the Ca 2+ concentration was 1%, the predicted glycemic index of noodles was the lowest and the resistant starch content was the highest. According to curve fitting based on the sensory evaluation results, the overall noodle acceptability was higher when hardness was between 3800 and 5200 g.
研究领域:
食品科学
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生物化学
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产品关联
DOI
PubMed
高影响因子
Gels
·
2022
·Vol. 8
·期 6
·343
·
IF 4.432
Tianzhu Shi,Zhengfeng Xie,Xinliang Mo,Yulong Feng,Tao Peng,Dandan Song
In this paper, functionalized sodium alginate hydrogel (FSAH) was prepared to efficiently adsorb heavy metals and dyes. Hydrazide-functionalized sodium alginate (SA) prepared hydrazone groups to selectively capture heavy metals (Pb2+, Cd2+, and Cu2+), and another functional group (dopamine grafting), serves as sites for adsorption methylene blue (MB), malachite green (MG), crystal violet (CV). Thermodynamic parameters of adsorption indicated that the adsorption process is endothermic and spontaneous. The heavy metals adsorption by FSAH was physical adsorption mainly due toΔHθ< 40 kJ/mol, and the adsorption of cationic dyes fitted with the Langmuir models, which indicated that the monolayer adsorption is dominated by hydrogen bonds, electrostatic interactions, and π-π interactions. Moreover, the adsorption efficiency maintained above 70% after five adsorption-desorption cycles. To sum up, FSAH has great application prospect.Keywords:sodium alginate;modification;heavy metals;dye;adsorption
研究领域:
材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Xue Wang,Huan Zhang,Qingdong He,Haifeng Xing,Ke Feng,Fang Guo,Wenbo Wang
A series of sodium alginate (SA) grafted polymer composite beads were synthesized by a solution free-radical graft polymerization reaction performed in a surface crosslinked alginate bead reactor. The outer surface of the precursor droplet containing reactants including SA, acrylamide (AM), N,N′ -methylene- bis -acrylamide (MBA), ammonium persulfate (APS), sepiolite (SP) and gelatin (GE) was instantly crosslinked with Ca 2+ ions to form a capsule-like bead when it was dropped into aqueous solution of calcium chloride , and simultaneously the reactants inside the capsule-like “bead reactor” were polymerized in-situ to form new composite beads with crosslinked network structure, abundant functional groups, excellent single or co-adsorption ability and easily separable advantages. The optimal composite bead shows high adsorption capacities of 390.78, 1425.65 and 533.91 mg/g toward Methylene Blue (MB), Basic Fuchsin (BF) and Pb(II), respectively. After adsorption with the composite bead, 99.71% of MB, 99.99% of BF and 99.97% of Pb(II) were removed from original dye or Pb(II) solutions. Moreover, above 99.22% of BF and 95.33% of Pb(II) was co-removed from their binary mixture (BF concentration, 100 mg/L; Pb(II) concentration, 50 mg/L). This paper provides a simple green way to synthesize efficient and recyclable biopolymer-based adsorbents capable of purifying dyes and heavy metal ions in water.
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jie Song,Lijun Chen,Yingnan Zhou,Zhiwen Yuan,Yuhua Niu,Zhiqiang Wei
With the rapid development of industrialization, the removal of heavy metal ions and small organic molecules from wastewater has triggered a hot debate. ZIF-8 was grown on a sodium alginate backbone using an in situ growth technique, the core-shell P-SMG@ZIF-8 was synthesized. It was also characterized by FTIR, XRD, SEM, UV–Vis and XPS, and the optimal conditions and mechanism of adsorption were explored. At pH 2.0, a contact time of 200 min, and 298 K, removal of Cu(II) and Ph up to 80.2 %, 65.6 % by P-SMG@ZIF-8, adsorption behavior consistent with Langmuir model for pseudo-secondary rates, the saturated adsorption of Cu(II) and Ph could reach up to 83.5812 mg/g and 78.1779 mg/g, respectively. And the adsorbed P-SMG@ZIF-8 is easy to separate and reusable, which is a cost-effective and efficient natural product-based adsorption material.
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2019
·
IF 6.044
Yu Bai,Yun Zhao,Yang Li,Jiachao Xu,Xiaoting Fu,Xin Gao,Xiangzhao Mao,Zhaoyong Li
In this study, we fabricated a soft, transparent UV-shielding film (Alg-Fe 3+ -EDTA) by crosslinking sodium alginate with a ferric ion solution containing EDTA. The obtained films were characterized via SEM, ATR-FTIR, XRD, TG and DTG; the results indicated that the synergistic gelation of ferric alginate and alginic acid existed in Alg-Fe 3+ -EDTA film. The Alg-Fe 3+ -EDTA film performance to be optimized under the following conditions: 1.6% Fe 3+ , 0.8% EDTA, and crosslinking duration of 12 min. The Alg-Fe 3+ -EDTA film had high visible light transmittance, the UV-C (200–280 nm) and UV-B (280–315 nm) shielding rates were 100%, and the UV-A (315–400 nm) shielding rate was 98.37%; the UPF reached 50+; additionally, the tensile strength and elongation-at-break were 56.85 MPa and 10.45%, respectively, and still have ultraviolet shielding effect under water environments or after strong light irradiation. This work provides an efficient method to improve the optical and mechanical ability of ferric alginate films.
研究领域:
材料科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2025
·
IF 5.6
Ying Huang,Zhengao Wang,Meimei Fu,Dongsong Lin,Fuyu Zhao,Keke Wu,Xia Ren,Xianjun Fu,Wuyi Zhou
Effective wound management remains a major clinical challenge, especially in preventing infections and promoting rapid healing. However, traditional wound dressings often lack multifunctionality, limiting their ability to support hemostasis and antibacterial protection. To address this challenge, in this work, a novel wound dressing was developed utilizing nano-cuttlebone particles, which are rich in calcium carbonate and chitin, to enhance hemostatic and antimicrobial functionality. The dressing, composed of polyvinyl alcohol, sodium alginate, and nano-cuttlebone, addresses the need for advanced wound care solutions. The particle size distribution of the powder was evaluated using a laser particle size analyzer, and the particle size of the nano-cuttlebone was around 75 nm. The drug release experiment showed that the drug release of nano cuttlebone hydrogel was 1.4 times that of micro cuttlebone hydrogel in 48 h. The antibacterial activity of the nano-cuttlebone-doped dressing against S. aureus was 97.32% and against E. coli was 99.99%. The cell scratch test showed that the nano-cuttlebone hydrogel gradually migrated to the central area, and its migration rate was 61.43% after 12 hours. The hydrogel also demonstrated excellent hemostatic ability in a mouse liver injury model and could rapidly stop bleeding within 1 min. In a full-thickness wound model, the nano-cuttlebone hydrogel enhanced collagen deposition and promoted faster wound closure. This study highlights the potential of marine biomaterials for developing multifunctional wound dressings to improve patient outcomes.
研究领域:
生物材料学
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创伤修复
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医学工程
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Yuanhong Cai,Peipei Xu,Runbing Huang,Jiayi Huang,Junhua Zhan,Junpeng Su,Ruiyun You,Yudong Lu
This study presents the development of a novel polysaccharide biomolecule composite microsphere system based on sodium alginate (SA) and tremella fuciformis polysaccharide (TFP) for the encapsulation and controlled release of camellia oil (CO). The system leverages the synergistic properties of these two bioactive biopolymers to enhance the protection and bioavailability of CO during simulated digestion. The microspheres, characterized by their spherical structure and uniform particle size distribution, were comprehensively evaluated for stability, elemental composition, and thermal stability using techniques such as scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR), and thermogravimetric analysis (TGA). The results confirmed a significant improvement in the elemental composition and surface properties of the microspheres due to the incorporation of CO, which enhanced their stability. In simulated digestion experiments, the microspheres demonstrated excellent gastric acid tolerance and intestinal release, achieving a high encapsulation efficiency of 99.59 % and an oil loading capacity of 80.67 %, effectively protecting and targeting the release of CO. Moreover, the microspheres exhibited significant antibacterial activity against Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ). Overall, the SA/TFP/CO microspheres represent an ideal delivery system for CO, demonstrating considerable potential in the fields of food science and biomedicine.
研究领域:
食品科学
·
生物医学
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Haike Li,Zhiyun Kong,Huan Zhang,Xiaolei Wang,Yaohua Xie,Xingqing Zhao,Yidan Hong
It is necessary to prepare a nanofiltration membrane with high permeation flux that can be used in the field of organic solvents. Gel membranes have a high solvent permeation flux, but their chained macromolecular structure is often unstable. In this study, tannic acid-bridged sodium alginate (TA x -Ca/FeSA) organic solvent nanofiltration (OSN) membranes were prepared by the phase transition method using aqueous Ca 2+ and Fe 3+ solutions as cross-linking agents. TA can interact with SA through hydrogen bonding hydrophobic bonding and other interactions to form an interpenetrating three-dimensional network structure. Compared with Ca/FeSA membrane, the average pore size of TA 0.125 -Ca/FeSA membrane was reduced from 1.03 nm to 0.74 nm, and the porosity was increased from 47.62 to 59.2 %. In addition, the TA 0.125 -Ca/FeSA membrane has the characteristics of a negative charge, super hydrophilicity, and high mechanical properties, exhibits a high permeation flux of 48.97 L·m −2 ·h −1 ·bar −1 with a rejection of 96.25 % for Congo red ethanol solution, has excellent solvent resistance, stain resistance, and self-cleaning ability. The TA 0.125 -Ca/FeSA membrane was demonstrated to have great potential for application in the fields of purification and solvent recovery.
研究领域:
材料科学
·
化学工程
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产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2024
·
IF 4
Yazhou Guo,Yonggang Du,Guibo Liu,Yuyan Bi,Weiqiang Xu,Yahui Cui,Yulei Jia
Herein, a novel and high-performance adsorbent, polyaniline-sodium alginate (PANI–SA) hydrogel microspheres were prepared via ion cross-linking technique for adsorption and removing methylene blue (MB) dye from wastewater. The processes involved synthesizing polyaniline (PANI) with macromolecular skeleton and doping it into sodium alginate (SA) to prepare hydrogel microspheres with high specific surface area, abundant functional groups, and excellent adsorption properties. The surface morphology, crystallinity, functional groups, thermal stability, pore size distribution, and specific surface area of PANI–SA hydrogel microspheres and their components were determined by SEM, XRD, FTIR, TGA, and BET. Various parameters, including polyaniline doped concentration, solution pH, initial dye concentration, adsorption time, and temperature were systematically investigated to understand their impact on the adsorption properties of PANI–SA. The results revealed a synergistic effect between PANI and SA, with PANI–SA exhibiting exceptional efficacy (1060.78 mg/g) in removing MB from aqueous solutions. The kinetics and isotherm adsorption behaviors were aptly described by the pseudo-first-order kinetic and the Langmuir isotherm models, respectively. Thermodynamic analyses confirmed the spontaneous and exothermic nature of adsorption. Furthermore, the PANI–SA hydrogel microspheres demonstrated excellent reusability, maintaining high adsorption capacity after 5 recycling rounds. Electrostatic interactions and hydrogen bond were found to be the primary mechanisms driving the adsorption process. This study not only contributes to the development of efficient and eco-friendly adsorption materials for dye wastewater treatment but also provides insights into the design and optimization of hydrogel adsorbents.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
Biomaterials Science
·
2020
·Vol. 9
·期 3
·960-972
·
IF 6.183
Hongjie Zhang,Qiuquan Cai,Yanhui Zhu,Weipu Zhu
Numerous efforts have been made to prepare hydrogels with injectability, adhesivity and osteogenic activity for bone regeneration. However, current hydrogels with these characteristics have limited application in clinical translation due to their complex chemical compositions, which causes difficulty in batch production. In this study, a multifunctional hydrogel with a binary component is prepared for bone regeneration. Dopamine (DA) is first grafted to alginate (Alg) by amidation reaction to give Alg-DA. Then an injectable hydrogel is facilely prepared by mixing strontium ions with the Alg-DA aqueous solution, utilizing the dynamic ionic bonds between the strontium ions and carboxyl groups of Alg-DA. Under the simulated oxidation conditions in vivo, the injectable hydrogel can form stable chemical crosslinkages owing to the presence of catechol groups on Alg-DA. In addition, the catechol groups endow the hydrogel with significant tissue adhesivity. More importantly, the strontium ions endow the hydrogel with osteogenic activity. As indicated by animal experiments, the strontium containing hydrogel scaffolds help to treat rat bone defects within 8 weeks compared to hydrogels without strontium and control groups. This simple hydrogel constructed by using a binary component has achieved several necessary functions, and is expected to be used as a scaffold for bone tissue engineering in clinical applications.
研究领域:
生物材料学
·
组织工程学
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）