Marine Drugs
·
2019
·Vol. 17
·期 8
·438
·
IF 3.772
Xiaoyang Liu,Zixu Wang,Fawen Yin,Yuxin Liu,Ningbo Qin,Yoshimasa Nakamura,Fereidoon Shahidi,Chenxu Yu,Dayong Zhou,Beiwei Zhu
In this study, three synthetic zinc-chelating peptides (ZCPs) derived from sea cucumber hydrolysates with limited or none of the common metal-chelating amino-acid residues were analyzed by flame atomic absorption spectroscopy, circular dichroism spectroscopy, size exclusion chromatography, zeta-potential, Fourier transform infrared spectroscopy, Raman spectroscopy and nuclear magnetic resonance spectroscopy. The amount of zinc bound to the ZCPs reached maximum values with ZCP:zinc at 1:1, and it was not further increased by additional zinc presence. The secondary structures of ZCPs were slightly altered, whereas no formation of multimers was observed. Furthermore, zinc increased the zeta-potential value by neutralizing the negatively charged residues. Only free carboxyl in C-terminus of ZCPs was identified as the primary binding site of zinc. These results provide the theoretical foundation to understand the mechanism of zinc chelation by peptides.Keywords:zinc-chelating peptide;sea cucumber;chelation mechanism
研究领域:
生物化学
·
营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER
·
2020
·
IF 4.231
Jie Guan,Fuchun Zhao,Tingting Gu,Huan Liu,Ming-Chao Luo,Shuangquan Liao
Natural rubber (NR) is widely applied in automobile industry, surgical rubber goods, and daily necessities due to its outstanding comprehensive properties originated from the unique non-rubber component and network architecture. Glucose as an endogenous component virtually exert an important influence during the microorganism or spontaneous coagulation of natural latex. However, such role of glucose on the reconstruction of NR molecular chains and corresponding network has not been paid wide attention to. Hence, we here examined the difference of molecular chain parameters and molecular chains network composition of raw NR coagulated by different glucose content. The results demonstrated that glucose exerted an important role on the molecular chain and molecular chain architecture via two main related action of glucose: metabolism and chelation. In this work, a possible mechanism was proposed to reveal the role of glucose on the reconstruction of natural network in raw NR from spontaneous coagulation assisted by glucose.
研究领域:
材料科学
·
生物学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Xueli Zhou,Weizhen Liu,Chen Tian,Siqi Mo,Xueming Liu,Hong Deng,Zhang Lin
The high value rare earth elements (REEs) recycling from wastewater remains a great challenge. In the present work, biological calcium carbonate (bio-CaCO 3 ) was functionalized by mussel-inspired polydopamine (PDA) chemistry to improve its Eu(III) adsorption in aqueous solutions. The functional groups of the organic matters in bio-CaCO 3 that served as both reductant and coupling agent were found to be able to effectively inhibit the auto-oxidation of PDA in alkaline environments, rendering a uniform and tight PDA coating on bio-CaCO 3 . The batch experiments indicated that the mussel-inspired PDA functionalized bio-CaCO 3 (bio-PDA) exhibited superior Eu(III) adsorption capacity in aqueous solutions. The adsorption isotherm was fitted well with the Langmuir model, and the maximum adsorption capacity was determined to be 151.52 mg/g. The adsorption kinetics followed pseudo-second-order model, suggesting that the adsorption was chemisorption. Based on the scanning electron microscope (SEM), energy dispersive X-ray spectrometer (EDS) and X-ray photoelectron spectroscopic (XPS) analyses, the possible Eu(III) adsorption mechanism of bio-PDA was proposed as the coordination of Eu(III) with the abundant catechol and amine/imine groups on the PDA coating. Our work has demonstrated great application potentials of bio-PDA as an efficient Eu(III) adsorbent and provided new insights into the interaction mechanism between PDA and Eu(III).
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
PLANT PHYSIOLOGY AND BIOCHEMISTRY
·
2025
·
IF 5.7
Jie Yang,Keran Zhu,Xiaoxi Chen,Feifei Tian,Chengyu Han,Zhikun Liang,Kaixuan Xiao,Ruixue Hao,Meng Liu,Xiangyu Zhou,Xueqin Wan,Qinglin Liu,Fan Zhang
Urban soil lead (Pb) pollution poses a pressing threat to ecosystems and public health. Phytoremediation has emerged as an effective solution to address this issue. Poplars are widely employed in urban greening owing to their fast growth and high biomass, rendering them prime candidates for Pb remediation. However, their innate remediation capacity remains constrained, therefore, it needs to further enhance by genetic improvement. Transcriptome sequencing (RNA-seq) has identified that PscCYP716A1 , a gene involved in brassinosteroid (BR) synthesis, is upregulated under Pb stress, indicating a potential role in Pb tolerance. This prompted a research question: Can PscCYP716A1 improve poplar's Pb tolerance? In this study, we obtained PscCYP716A1 -overexpression poplars (OE lines, OE-13 and OE-42) and RNA interference PscCYP716A1 -expression poplars (RNAi lines, RI-33 and RI-23). The overexpression poplars significantly enhanced Pb tolerance, and increased Pb accumulation compared to wild-type (WT). Further analysis revealed that PscCYP716A1 enhances Pb tolerance by improving the antioxidant system and Pb chelation. However, when exogenous brassinazole (BR biosynthesis inhibitor, BRZ) was sprayed on poplar under Pb stress, all advantages of OE lines disappeared. According to the results of analysis, the improvement of antioxidant and chelation capacities conferred by PscCYP716A1 may be related to its participation in the BR synthesis pathway. In summary, our results revealed the physiological mechanism and detoxification processes facilitated by PscCYP716A1 , and underscored its potential as a genetic tool for enhancing phytoremediation in Pb-contaminated urban environments. These findings provide a theoretical foundation and technical support for the application of engineered poplars in remediating soil Pb pollution.
研究领域:
植物生理学
·
环境修复
·
分子生物学
·
重金属毒理学
·
植物遗传工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Song Zhang,Yang Shen,Peng Qiu,Mengjia Fang,Peichuang Li,Xiangning Du,Zhengying Deng,Wanhao Cai,Hui-Li Wang
The specific binding capacity between chitosan and heavy metal ions is critical in food safety, which is closely regulated by its degree of deacetylation (DD). However, the underlying mechanism governing the impact of DD remains unclear. Here we employ a combination of experiments and simulations to study the interaction between chitosan and Pb 2+ across multiscale at different DD. At the molecular level, Pb 2+ can chelate individual chitosan chains simultaneously via multiple interaction sites, which is enhanced with rising DD and leads to more ordered molecular packing. This molecular arrangement then develops to a nanoscale aggregation process, where the aggregation size, rate, and mechanical stability all show a positive correlation with DD. Such aggregation ultimately leads to enhanced macroscale structures, where the strain and tensile stress are significantly increased by 2 to 3-folds and further rises with increasing DD. These observed effects are governed by a unified mechanism: deacetylation introduces more amino groups that serve as stronger chelation sites than acetyl groups, thereby enhancing Pb 2+ binding across length scales. These findings provide foundation for the development and application of chitosan in the food industry, such as food preservation, anti-heavy-metal packaging, and food purification.
研究领域:
食品科学
·
高分子材料学
·
环境毒理学
·
食品安全
·
分子生物学
·
纳米科技
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Chengjia Dan,Yue Wang,Daikuan Huang,Yang Cao,Dabin Zhang
Leakages of electrolytic manganese slag (EMS) disposal sites pose a significant threat to soil and groundwater, necessitating effective in situ remediation technologies. This study presents a multi-scale analysis to elucidate the enhanced impermeability mechanism of EMS composite modified by sodium polyacrylate (PAAS). By integrating macroscopic performance testing (compressive strength, permeability, corrosion resistance, and pollutant leaching), molecular dynamics (MD) simulations, and advanced spectroscopic/microscopic techniques (FTIR, XPS, and EDS mapping), we establish a direct link between macroscopic properties and underlying molecular-level interactions. Results demonstrate that an optimal PAAS/EMS mass ratio of 0.2 significantly enhances compressive strength (12.3-fold increase), reaching 2.78 MPa, and reduces the permeability coefficient to 1.318 × 10 −8 cm/s, with leachate concentrations meeting relevant water quality standards. This performance improvement stems from a synergistic multi-scale effect: macroscopically, well-dispersed PAAS forms a crosslinked network, filling structural defects within the EMR matrix and encapsulating the CaSO 4 ·2 H 2 O hard phase; at the molecular level, MD simulations reveal that PAAS chains undergo ion exchange (Na + with Mn 2+ ) and chelation (between -COO - and Mn 2+ ), forming a multi-crosslinked polymer network that densifies the microstructure and effectively impedes contaminant migration. FTIR and XPS analyses corroborate these molecular interactions, confirming that the enhanced impermeability arises from the synergistic effects of polymerization, ion exchange, and chelation. This study provides a new approach for controlling environmental risks associated with EMS, demonstrating the efficacy of multi-scale analysis in optimizing material performance.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Xiaohao Gan,Yan Zhang,Lina Zheng,Yuxuan Wang,Xuancheng Shen,Feiyan Wu,Wenxiang Wang,Ye He
Histamine is usually regarded as an important indicator for monitoring food freshness, and the detection of histamine is crucial for ensuring food safety. Herein, a high-resolution colorimetric assay for histamine determination based on nanozyme-inhibited TMB 2 + -mediated etching of gold nanorods (AuNRs) was proposed. Hydrothermal synthesis yielded CDsEDTA@Fe³ ⁺ nanozymes with Fe³ ⁺ active sites, with Vₘ = 11.17 × 10⁻⁸ M·s⁻¹ for TMB oxidation. The strong chelation between Fe 3+ and the imidazole group on histamine modulates the catalytic activity of the carbon dot nanozymes, thereby regulating the production of the oxidative end product TMB 2+ . Upon the introduction of AuNRs as the final colorimetric substrate, a rainbow-like spectrum of 5--6 distinct color changes was observed, enabling simple and rapid visual monitoring of food freshness. The limits of detection and quantification are 13.16 μM and 18.49 μM, respectively. This strategy has been effectively applied to track the genuine spoilage of shrimp and mackerel under diverse storage situations, with a recovery rate of 94.64 %-110.65 % and an RSD (n = 3) < 6 %, showing significant promise for swift and convenient detection of histamine in food products, thereby enabling the assessment of food freshness onsite.
研究领域:
食品科学与技术
·
分析化学
·
纳米技术
·
生物传感器
·
食品安全
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Junjie Ding,Xiaoyu Sun,Qile Zhao,Xiangyu Liu,Qingdong He,Yue Yin,Jinfang Wu,Fang Guo,Wenbo Wang
Polysaccharide-based hydrogels have shown exceptional potential for rare earth elements (REEs) recovery due to their abundant functional groups and three-dimensional (3D) porous structures. However, their practical application is frequently constrained by insufficient adsorption efficiency, particularly for low-concentration REEs. To address this challenge, we developed a chitosan/poly(acrylic acid-co-amidoxime)/attapulgite composite hydrogel (denoted as CS/AA x AO 1-x @A) through copolymerization of acrylic acid (AA) and acrylonitrile (AN) followed by amidoximation. The designed bifunctional network, containing both carboxyl and amidoxime groups, exhibits substantially enhanced Gd(III) adsorption capacity through synergistic coordination: carboxyl groups pre-concentrates REEs via electrostatic attraction, while the pre-concentrated REEs are subsequently captured by adjacent amidoxime groups through strong chelation. The optimal formulation (CS/AA 0.6 AO 0.4 @A; AA/AO = 4:6) achieves an exceptional maximum capacity of 267 mg/g at 303 K and maintains 99.9 % removal efficiency for low-concentration Gd(III) solutions, surpassing single-functional hydrogel counterparts by 40–60 %. DFT calculations confirm the enhanced binding affinity originates from cooperative Gd(III) chelation between adjacent carboxyl and amidoxime groups. The hydrogel enables complete Gd(III) extraction from complex aqueous matrices containing multiple interfering ions while maintaining >95 % efficiency over five regeneration cycles. The adsorption mechanism involves synergistic chemical complexation (primary), ion exchange (secondary), and electrostatic interactions, as confirmed by kinetic and isotherm analyses. This study presents a molecular design strategy for developing high-performance REE adsorbents, with important implications for sustainable resource recovery and water purification technologies.
研究领域:
材料科学
·
环境科学
·
化学工程
·
高分子科学
·
无机化学
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2023
·Vol. 28
·期 14
·5459
·
IF 4.6
Guangyuan Hu,Zhiwei Wang,Weiye Zhang,Hongxing He,Yi Zhang,Xiujun Deng,Weili Li
The recovery of precious metals from secondary resources is significant economically and environmentally. However, their separation is still challenging because they often occur in complex metal ion mixtures. The poor selectivity of adsorbents for gold in complicated solutions prevents further application of adsorption technology. In this study, a Zr-based MOF adsorbent, MIL-161, was synthesized using s-tetrazine dicarboxylic acid (H2STz) as an organic ligand. MIL-161 demonstrated a high adsorption capacity of up to 446.49 mg/g and outstanding selectivity for gold(III) in a simulated electronic waste solution as a result of the presence of sulfur- and nitrogen-containing groups. In addition, the MIL-161 adsorbents were characterized using Fourier transform infrared (FT-IR), field emission scanning electron microscopy (FESEM), thermogravimetric analysis (TG), Brunner–Emment–Teller (BET), and X-ray photoelectron spectroscopy (XPS). Additionally, the adsorption kinetics, isotherms, and thermodynamics of the MOF adsorbents were also thoroughly examined. More importantly, the experimental results and DFT calculations indicate that chelation and electrostatic interactions are the main adsorption mechanisms.Keywords:selectivity;e-wastes;metal–organic framework;gold;adsorption;DFT calculations
研究领域:
材料科学
·
环境工程
·
化学工程
·
可持续化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Xin Li,Hebo Shi,Ruixue Hong,Yingying Peng,Zhaoqing Liu,Boya Xiao,Shaoheng Yang,Chang-an Xu,Zhuohong Yang,Yang Hu
The corrosion protection of organic coatings for metal substrates is generally limited because of the unavoidable coating micropores and cracks, even the coating anticorrosion function will lose when it is damaged. Although the addition of nanofillers into the organic coating matrix can effectively address the above issues, it is challenging to facilely and wholesale construct surface-modified nanofillers with synergistic anticorrosion ability of physical barrier, passivation and chelating effect. In this study, we develop a simple one-pot approach for preparing polypyrrole (PPy) modified graphene oxide (GO) nanofillers with the doping of phytic acid (Ph) (namely GO-PPy@Ph nanoparticles) and then incorporating them into epoxy resin (EP) coating system to form the anticorrosion nanocomposite coatings. The research results display that the GO-PPy@Ph nanoparticles can uniformly disperse in the EP coatings to improve their anti-penetrant ability against corrosive media. And the introduction of GO-PPy@Ph nanoparticles effectively enhances the coating adhesion strength and mechanical performance. Moreover, the anticorrosion tests show that the impedance modulus at 0.01 Hz of GO-PPy@Ph coating after 60-day immersion in 3.5 wt% NaCl solution remains at about 10 10 Ω cm 2 . The dramatical anticorrosive performance of the GO-PPy@Ph coating with self-healing performance is attributed to the synergistic protection of impermeable GO-PPy@Ph nanosheets, passivation function of PPy and metal chelation effect of Ph. This study provides an effective and universal avenue to construct multifunctional nanofillers with the synergistic anticorrosion of high physical barrier, passivation and metal chelating effects for developing anticorrosive nanocomposite coatings with high performances, which have highly attractive potential in the commercialization applications of metal corrosion protection.
研究领域:
材料科学
·
腐蚀工程
·
纳米技术
·
涂层技术
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Bio Materials
·
2024
·
IF 4.6
Yaqi Liu,Xing Lu,Shiling Liu,Yijun Li,Xiwen He,Langxing Chen,Yukui Zhang
As important biomarkers of many diseases, glycoproteins are of great significance to biomedical science. It is essential to develop efficient glycoprotein enrichment platforms and investigate their adsorption mechanism. In this work, a conspicuous enrichment strategy for glycoproteins was developed by using an electrospun fiber membrane wrapped with polydopamine (PDA) and modified with 3-aminophenylboronic acid and nickel ions, named PAN/DA@PDA@APBA/Ni. The enrichment characteristics of PAN/DA@PDA@APBA/Ni toward glycoproteins were explored through adsorption behavior. Thanks to the existence of two sites of interaction (metal ion chelation and boronate affinity), PAN/DA@PDA@APBA/Ni exhibited significant enrichment capacity for glycoproteins, ovalbumin (604.6 mg/g), and human immunoglobulin G (331.0 mg/g). The adsorption kinetic results of glycoprotein ovalbumin on PAN/DA@PDA@APBA/Ni conform to the pseudo-first-order kinetic model in the first adsorption stage, while the second half adsorption stage is more in line with the pseudo-second-order kinetic model. Moreover, the physical characteristics of PAN/DA@PDA@APBA/Ni and subsequent adsorption experiments on electrospun fiber modified with only phenylboronic acid or nickel ions both confirmed two sites of interaction (metal ion chelation and boronate affinity, respectively). Furthermore, a stepwise elution method with dual-affinity interaction was designed and successfully applied to enrich glycoproteins in real biological samples. This work provides an idea for sample pretreatment, especially for the design of dual-affinity materials in glycoproteins enrichment.
研究领域:
生物医学科学
·
材料科学
·
分析化学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Wenwei Zhan,Liang Gao,Xue Fu,Sajid Hussain Siyal,Gang Sui,Xiaoping Yang
In this study, the ultra-lightweight and robust three-dimensional graphene/polydopamine modified multiwalled carbon nanotube (MWCNT-PDA) hybrid aerogels were prepared via a viable green route and applied to highly efficient heavy metal ions adsorption. No additional reducing agents were required during the molding of the hybrid aerogel, thus greatly reducing the environment pollution emissions. The MWCNT-PDA in right amounts provided the hybrid aerogels with satisfying structure stability and effectively prevented the stacking of GO sheets, as well as exposed more active sites to improve the adsorption of heavy metal ions. Benefiting from the large specific surface area, porous structure and competent active sites, the resulting hybrid aerogels showed superior adsorption performance for heavy metal ions, and the saturated adsorption capacities were as large as 318.47 and 350.87 mg g −1 for Cu(II) and Pb(II), respectively, calculated by the Langmuir isotherm model. The research revealed that the synergistic effects of the surface complexation and chelation between active sites in hybrid aerogels and heavy metal ions were the dominant adsorption mechanisms. High adsorption capacity and easy separation from water after adsorption make the hybrid aerogels an ideal choice for heavy metal ions treatment in practical application.
研究领域:
环境科学
·
材料科学
·
纳米技术
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）