Nano n-propylsulfonated γ-Al2O3: a new, efficient and reusable catalyst for synthesis of spiro[indoline-3,4-pyrazolo[3,4-e][1,4]thiazepine]diones in aqueous media
Nano n -propylsulfonated γ-Al 2 O 3 is easily prepared by the reaction of nano γ-Al 2 O 3 with 1,3-propanesultone. This reagent can be used as an efficient catalyst for the synthesis of spiro [indoline-3,4-pyrazolo[3,4- e ][1,4]thiazepine]diones in aqueous media. This new method consistently has the advantages of excellent yields and short reaction times. Further, the catalyst can be reused and recovered several times. Copyright © 2013 John Wiley & Sons, Ltd.
研究领域:
催化化学
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有机合成
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绿色化学
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纳米材料
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药物化学
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