MOLECULES
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2024
·Vol. 29
·期 3
·618
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IF 4.2
Dongmei Li,Senlin Peng,Xu Zhou,Lingyi Shen,Xianjiong Yang,Hong Xu,Carl Redshaw,Chunlin Zhang,Qilong Zhang
In this study, we synthesized a coumarin–hemicyanine-based deep red fluorescent dye that exhibits an intramolecular charge transfer (ICT). The probe had a large Stokes shift of 287 nm and a large molar absorption coefficient (ε = 7.5 × 105L·mol−1·cm−1) and is best described as a deep red luminescent fluorescent probe withλem= 667 nm. The color of probe W changed significantly when it encountered cyanide ions (CN−). The absorption peak (585 nm) decreased gradually, and the absorption peak (428 nm) increased gradually, so that cyanide (CN−) could be identified by the naked eye. Moreover, an obvious fluorescence change was evident before and after the reaction under irradiation using 365 nm UV light. The maximum emission peak (667 nm) decreased gradually, whilst the emission peak (495 nm) increased gradually, which allowed for the proportional fluorescence detection of cyanide (CN−). Using fluorescence spectrometry, the fluorescent probe W could linearly detect CN−over the concentration range of 1–9 μM (R2= 9913, RSD = 0.534) with a detection limit of 0.24 μM. Using UV-Vis spectrophotometry, the linear detection range for CN−was found to be 1–27 μM (R2= 0.99583, RSD = 0.675) with a detection limit of 0.13 μM. The sensing mechanism was confirmed by1H NMR spectroscopic titrations,13C NMR spectroscopy, X-ray crystallographic analysis and HRMS. The recognition and detection of CN−by probe W was characterized by a rapid response, high selectivity, and high sensitivity. Therefore, this probe provides a convenient, effective and economical method for synthesizing and detecting cyanide efficiently and sensitively.
研究领域:
化学
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分析化学
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环境科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2024
·
IF 4
Yuyang Luo,Shiyu Zheng,Congcong Dong,Haojie Yu,Kunming Liu,Juanhua Li,Jinbiao Liu
An innovative dual-modal colorimetric and fluorometric probe MDXM is synthesized based on the dihydro-1 H -xanthene motif via Knoevenagel reaction. The incorporation of a malononitrile group into the dihydro-1 H -xanthene motif via a double bond results in an extensive macroconjugated π-system, which endows MDXM with a pronounced molar absorptivity and effectively quenches the intramolecular charge transfer (ICT) effect. Upon exposure to hypochlorite, the C = C bond in MDXM undergoes cleavage, resulting in the formation of an aldehyde group. This process restores the ICT effect and manifests as a clear fluorescent ''turn-on'' signal at 530 nm, with a remarkably linear response across the ClO − concentration range of 0–60 μM. The probe achieves a notably low detection limit of 7.14 nM, reflecting its exceptional sensitivity. In the presence of 15 common metal ions and oxidizing agents, MDXM can specifically identify hypochlorite with excellent anti-interference ability. The response mechanism of MDXM to hypochlorite was confirmed through Nuclear Magnetic Resonance (NMR) spectroscopy and computational Density Functional Theory (DFT) calculations. The practical applicability of MDXM is underscored by its successful implementation in analyzing hypochlorite in 5 varied real water samples. This showcases MDXM' s promise for environmental and analytical chemistry, providing a robust tool for hypochlorite detection in diverse settings.
研究领域:
分析化学
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环境科学
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生物医学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Miao Zhang,Xiaoyu Shi,Guiping Zhang,Chunli Xu,Baoxin Li
Recognizing and quantifying enantiomers of chiral molecule is of great importance in chemical, biological and pharmaceutical fields. Herein, we presented one simple-yet-efficient method of sensing tyrosine (Tyr) enantiomers. In this sensing, silver triangular nanoplates (AgTNPs) were used as colorimetric probes. L-Tyr quickly induced the color of AgTNPs solution to change from dark blue to light gray, whereas D-Tyr induced no change of the AgTNPs solution color. The obvious color change enables the naked eye to recognize Tyr enantiomer. The visual method was used to detect the enantiometric excess value of L-Tyr in the whole range (−100 % ∼ 100 %). This chiral sensing can be finished within 5 min using one simple ultraviolet–visible spectrometer or naked eye. Furthermore, the mechanism of this chiral sensing was explored. It was confirmed that this chiral sensing was based on AgTNPs’ intrinsic chirality. This chiral sensing is rapid, simple, and low-cost, and has great potential for chiral determination of Tyr.
研究领域:
化学
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生物学
·
药学
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产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2018
·Vol. 10
·期 47
·5731-5737
·
IF 2.073
Q. Huang,Y. T. Chen,Y. W. Ren,Z. Y. Wang,Y. X. Zhu,Y. Zhang
A new rhodamine 6G derivative (R6GHP) has been synthesized for quick recognition of copper(II) ions (Cu2+) in aqueous solutions. The structure of R6GHP has been characterized by nuclear magnetic resonance and electrospray ionization mass spectrometry. Upon binding of Cu2+, the fluorescence intensity remarkably increases with about 36-fold enhancement. In addition, the color change from colorless to pink is visible to the naked eye. In optimal conditions, the fluorescence intensity and absorbance of R6GHP show good linearity with concentration of Cu2+ in the ranges of 1.0 × 10−6 to 1.0 × 10−5 mol L−1 and 1.0 × 10−6 to 1.2 × 10−5 mol L−1, respectively, with detection limits of 3.9 × 10−7 mol L−1 and 1.0 × 10−6 mol L−1. Besides, it has been successfully applied to detect Cu2+ in two water samples.
研究领域:
分析化学
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环境科学
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产品关联
DOI
高影响因子
Frontiers in Chemistry
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2017
·
IF 3.994
Li Xinjuan,Wang Kai,Ma Nana,Jia Xianbin
Naked-eye detection of amino acids (AA) in water is of great significance in the field of bioanalytical applications. Herein, polymerized ionic liquids (PILs) with controlled chain length structures were synthesized via reversible addition–fragmentation chain-transfer (RAFT) polymerization and post-quaternization approach. The AA recognition performance of PILs with different alkyl chain lengths and molecular weights was evaluated by naked-eye color change and ultraviolet-visible (UV–vis) spectral studies. These PILs were successfully used for highly sensitive and selective detection of Arg, Lys, and His in water. The recognition performance was improved effectively with increased molecular weight of PILs. The biosensitivity of the PILs in water was strongly dependent on their aggregation effect and polarization effect. Highly sensitive and selective detection of AA was successfully accomplished by introducing positively charged pyridinium moieties and controlled RAFT radical polymerization.
研究领域:
分析化学
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生物传感
·
材料科学
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DOI
PubMed
高影响因子
TALANTA
·
2021
·
IF 6.057
Dandan Zhao,Yijun Huang,Huixiang Ouyang,Bingfang Shi,Suping Li,Shengyu Chen,Shulin Zhao
Changing a detection analyte into a colored material is a key challenge for visual discrimination of isomers. In this work, a novel fluorescent probe incorporating Cu-doped carbon dots (Cu-CDs), for the first time, was developed for naked-eye discrimination of phenylenediamine isomers and highly sensitive ratiometric fluorescence detection of H 2 O 2 . In this strategy, Cu-CDs were synthesized by a facile hydrothermal approach using citric acid , formamide , and CuCl 2 as reactants. The prepared Cu-CDs exhibited outstanding peroxidase-like activity and stability. Consequently, a chemosensor platform based on Cu-CDs was constructed to enable naked-eye discrimination of phenylenediamine isomers through the H 2 O 2 -mediated oxidation reaction. Moreover, a Cu-CDs-based ratiometric fluorescence sensor was proposed as a means to sensitively detect H 2 O 2 with a detection limit of 5.0 nM. The sensor was further employed for monitoring H 2 O 2 in human serum, indicating its potential applications in other biologically related study.
研究领域:
分析化学
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生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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