JOURNAL OF HAZARDOUS MATERIALS
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2020
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IF 9.038
Zheng-Zhe Zhang,Yu Zhang,Ya-Fei Cheng,Ren-Cun Jin
The increase of emerging contaminants, such as surfactants, is one of the major challenges to biological wastewater treatment. However, the potential impact of linear alkylbenzene sulphonates (LAS), a major class of anionic surfactants, on anammox process is unclear. The long-term effects of sodium dodecyl benzene sulfonate (SDBS, as a model LAS) on reactor performance, microbial community and sludge properties were investigated in this study. The presence of 5 mg L −1 SDBS promoted the release of extracellular microbial products from anammox granules and the wash-out of anammox population via effluent. Despite sludge disaggregation, the reactor performance was robust to the exposure of 5 mg L −1 SDBS due to functional redundancy. With the further increase of SDBS to 10 mg L −1 , the metabolic activity of anammox biomass and the transcription and post-translation of hydrazine dehydrogenase were significantly decreased. The potential mechanism might be associated with the damage on cell membrane that induced the leakage of intracellular matrix. These results highlight the need to consider the potential risk of LAS to operation of anammox process in biological wastewater treatment plant.
研究领域:
环境工程
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微生物学
·
水处理
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产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2017
·Vol. 25
·期 1
·205-216
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IF 3.417
Xu Qinqin,Song Longchu,Zhang Lihua,Hu Gang,Chen Qin,Liu Enhui,Liu Yu,Zheng Qiang,Xie Haibo,Li Nanwen
The reversible reaction of the hydroxyl groups in cellulose with CO 2 in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) results in a rapid and effective derivative dissolution of cellulose in DMSO, by which a series of cellulose acetate propionate (CAP) and cellulose acetate butyrate (CAB) with various degrees of substitution (DS) were synthesized controllably without adding external catalysts. Wherein DBU not only achieves the dissolution of cellulose, but also acts as an efficient organocatalyst for the subsequent cellulose derivatization. The DS of CAB and CAP can be tuned by changing the feed molar ratio of propionic (butyric) anhydride/acetic anhydride and the reaction temperature. The structural and thermal properties of the products were characterized by several analytical techniques including NMR, FT-IR, and TGA. The CO 2 /DBU/DMSO dissolution system provides a new platform for controllable synthesis of mixed cellulose esters with high efficiency under mild conditions.
研究领域:
材料科学
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有机化学
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产品关联
DOI
高影响因子
Aerospace
·
2019
·Vol. 6
·期 4
·47
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IF 0
Suhang Chen,Yue Tang,Wei Zhang,Ruiqi Shen,Hongsheng Yu,Yinghua Ye,Luigi T. DeLuca
The low regression rates for hydroxyl-terminated polybutadiene (HTPB)-based solid fuels and poor mechanical properties for the alternative paraffin-based liquefying fuels make today hybrid rocket engines far from the outstanding accomplishments of solid motors and liquid engines. In this paper, a survey is conducted of several innovative methods under test to improve solid fuel properties, which include self-disintegration fuel structure (SDFS)/paraffin fuels, paraffin fuels with better mechanical properties, high thermal conductivity fuels and porous layer combustion fuels. In particular, concerning HTPB, new results about diverse insert and low-energy polymer particles enhancing the combustion properties of HTPB are presented. Compared to pure HTPB, regression rate can be increased up to 21% by adding particles of polymers such as 5% polyethylene or 10% oleamide. Concerning paraffin, new results about self-disintegrating composite fuels incorporating Magnesium particles (MgP) point out that 15% 1 μm- or 100 μm-MgP formulations increase regression rates by 163.2% or 82.1% respectively, at 335 kg/m2·s oxygen flux, compared to pure paraffin. Overall, composite solid fuels featuring self-disintegration structure appear the most promising innovative technique, since they allow separating the matrix regression from the combustion of the filler grains. Yet, the investigated methods are at their initial stage. Substantial work of refinement in this paper is for producing solid fuels to fulfill the needs of hybrid rocket propulsion.Keywords:hybrid;regression rate;self-disintegration;HTPB;paraffin;low-energy polymer;magnesium
研究领域:
航空航天工程
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材料科学
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产品关联
DOI
CHEMICAL PHYSICS LETTERS
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2023
·
IF 2.8
Han Zhang,Xuan Wang,Hao Ding
Herein, SiO 2 -TiO 2 composite (STC) photocatalysts were prepared through placing SiO 2 microspheres in TiOSO 4 solution and calcining at high temperature. Using STC (containing only 5.09 wt% TiO 2 ), the degradation rate to MO with a concentration of 10 ppm was 100% at 50 min of UV illumination. The cost of the photocatalyst and the cleanliness of the preparation process were ensured due to the use of TiOSO 4 as the titanium source and the water as the solvent. Therefore, not only the photocatalytic effect and application performance of TiO 2 were improved, but realized the cleanliness of the preparation process and reduced the cost.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
BIOCHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 3.8
Li Zhang,Yu Yan,Diannan Huang,Liansong Gao,Rongxin Zhang
Anaerobic fermentation technology presents significant advantages in waste activated sludge treatment, encompassing sludge reduction, detoxification, and resource recovery, primarily by generating high-value volatile fatty acids (VFAs). This study systematically investigated the enhancement effects of Fe²⁺/sodium percarbonate (SPC) pretreatment on sludge disintegration and organic matter hydrolysis. The optimal pretreatment conditions (initial pH=3, SPC dosage=0.3 g/g TSS, Fe²⁺ dosage=0.3 g/g TSS) resulted in a maximum VFAs production of 1598 mg COD/L, representing a 7.26-fold increase compared to untreated sludge. Under these conditions, acetic acid accounted for 52.9 % of the total VFAs. The mechanistic analysis demonstrated that Fe²⁺/SPC pretreatment selectively enriched hydrolytic-acidogenic microbial communities while inhibiting VFAs-consuming populations, thereby directing metabolic flux toward acid accumulation. These findings establish an innovative technical approach and provide a mechanistic framework for advanced resource recovery from waste activated sludge.
研究领域:
环境工程
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微生物学
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产品关联
DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
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2023
·
IF 5.9
Gul Muhammad,Parisa Jahanbakhsh-Bonab,Wenlong Xiong,Yongkun Lv,Shen Zhang,Anqi Zhao,Jaber Jahanbin Sardroodi,Jingliang Xu,Md Asraful Alam
Microalgae as a source of natural lutein get increasing attention since they feature a high quantity and quality of this pigment. Recalcitrance of the microalgal cell wall declines the bioaccessibility, bioavailability, and digestibility of the beneficial compounds contained in the microalgae. This study aimed to evaluate the influence of deep eutectic solvent (DES) based approaches for the disintegration of Chlorella pyrenoidosa cells for lutein recovery and explore the underlying mechanism. The results showed that choline chloride-ethylene glycol DES (ChCl:EG 1:2) achieved a better cell disintegration and lutein stability than other DESs. Molecular dynamics simulations revealed that chloride anion (Cl − ) dominated the dissolution of cellulose for breaking down cell wall structure of C. pyrenoidosa . Solvent screening and process optimization resulted in 239.92 mg/100 g lutein yield with ethanol solvent under optimized condition. Disintegration significantly increased the release of lutein from microalgae. This study provided the theoretical guidance and experimental prove of improve lutein extraction from microalgal biomass in a green and sustainable extraction procedure.
研究领域:
生物技术
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化学工程
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环境科学
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产品关联
DOI
高影响因子
Fermentation-Basel
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2024
·Vol. 10
·期 5
·247
·
IF 3.3
Jinxun Lei,Zhihong Xu,Yong Chen,Guo Yu,Zexiang Liu,Shuangfei Wang,Jian Zhang,Kelin Li,Li Xie
The lignin derivatives generated during pulping might be responsible for the suboptimal performance of anaerobic reactors during the treatment of pulping wastewater. However, the exact mechanisms by which these derivatives exert influence remain unclear. This study investigated the influence of lignin derivatives, simulated using humic acids (HAs), in anaerobic granular sludge (AnGS). Compared to the enzymes present during floc-bonding and granule-bonding, the HAs impeded the conversion of unhydrolyzed substrates into methane and caused considerable inactivation of free enzymes. Simultaneously, the HAs suppressed agglomeration and weakened the strength of the AnGS. Furthermore, calcium ions helped maintain the integrity of the sludge structure. Therefore, the inhibition of extracellular enzymes using lignin derivatives delays the methanation of unhydrolyzed substrates, resulting in a reduced biomass within AnGS reactors owing to sludge disintegration and biomass loss. This study serves as a reference for investigating the persistent risks originating from lignin derivatives associated with using anaerobic granular-sludge bed reactors to treat pulping wastewater.
研究领域:
环境工程
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废水处理
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生物技术
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产品关联
DOI
高影响因子
Journal of Cleaner Production
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2021
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IF 9.297
Yu-Ting Zhang,Wei Wei,Bing-Jie Ni
Zinc oxide nanoparticles (ZnO NPs) has been documented to accumulate in waste activated sludge (WAS). Nevertheless, its potential effect on hydrogen accumulation during anaerobic fermentation has never been reported. Such impact exists in anaerobic sludge treatment systems but is unrecognized before. Therefore, this work aims to explore the effect of ZnO NPs on hydrogen accumulation during WAS fermentation while avoiding hydrogen consumption by maintaining pH around 10. Deep insights into the mechanisms of the enhanced hydrogen production after dosing ZnO NPs can then be provided. The 21.1 to 74.0 mL-H 2 /g-VS hydrogen yields were obtained after dosing 0–150 mg/g-TS ZnO NPs into the system, which is 2.5 times higher than the control. The zinc ions released from ZnO NPs did not pose obvious cytotoxic effect on organisms based on the mechanism exploration of this study. The reactive oxygen species (ROS) induced by ZnO NPs facilitated sludge disintegration and improved the biodegradability of released organics, but restrained the bio-processes of hydrolysis and acetogenesis simultaneously. This was further verified by the microbial community analysis, as the abundance of key microbes related to hydrolysis and acetogenesis was reduced evidently in the presence of 150 mg/g-TS ZnO NPs. This study would provide a green and economic strategy for the sustainable engineering application of WAS containing ZnO NPs.
研究领域:
环境工程
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生物技术
·
可持续能源
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产品关联
DOI
高影响因子
JOURNAL OF FOOD ENGINEERING
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2024
·
IF 5.3
Lang-Hong Wang,Bing Yan,Danli Tang,Zhong Han,Jian Li,Xin-An Zeng
The soaking plum wine production is a time-intensive process that relies on the effective extraction of flavor compounds, colorants, and aromas from green plums during soaking. In this study, we explored the application of pulsed electric field (PEF) pretreatment as a novel approach to improve the quality and shorten the production cycle of plum wine. The optimization of PEF pretreatment parameters (4 kV/cm, a pulse count of 5000, a pulse width of 10 μs, and a pulse frequency of 80 Hz) was conducted based on the disintegration index Z-value of green plum cells. Results revealed that PEF pretreatment positively influenced several key parameters by facilitating the dissolution of organic acids, phenolic compounds and aroma profile, which contribute to color and flavor in plum wine. The study highlights the potential of PEF as a valuable tool in soaking plum wine, for enhancing the efficiency and quality of fruit wine production.
研究领域:
食品科学
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饮料技术
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电化学处理
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产品关联
DOI
高影响因子
Advanced Healthcare Materials
·
2019
·Vol. 8
·期 21
·1900898
·
IF 6.27
Ailin Hou,Guilan Quan,Beibei Yang,Chao Lu,Minglong Chen,Dan Yang,Lili Wang,Hu Liu,Xin Pan,Chuanbin Wu
The precise delivery of traditional dissolving microneedles (TDMNs) is often limited by the incomplete insertion due to the skin deformation, and the topical irritation is inevitable after long application, which ultimately results in compromised therapeutic efficacy. The aim of this study is to develop a rapidly separating dissolving microneedles (RSDMNs) system to achieve precise drug delivery. Therapeutic molecules are concentrated in the needle tip, while the blank separating part allows it to counteract skin indentation and rapidly separate from the base part. For rational design of an ideal separating part, and the molecular interactions between polymer and sugar are explored to make a good balance between mechanical performance and disintegration rate. The optimal RSDMNs can rapidly disintegrate in the mimic skin within 30 s, and the generated micropores in the skin reseal quickly. The ex vivo drug permeation of RSDMNs is significantly higher than that of TDMNs due to the complete needle imbed aided by the separating part. Furthermore, RSDMNs exhibit excellent in vivo anti-inflammation effect by remarkably down regulating the expression of TNF-α, IL-1β, and IL-6. In conclusion, the RSDMNs can reach precise drug delivery in a short time, which are more reliable for the self-administration strategy in the future.
研究领域:
药学
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生物医学工程
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药物递送系统
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透皮给药
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DOI
高影响因子
BIOMATERIALS
·
2024
·
IF 12.8
Jingjing Shen,Kai Feng,Jing Yu,Yaxuan Zhao,Ruifang Chen,Hehua Xiong,Yiling Ruan,Zhengtao Xu,Tao Zhang,Xiaolian Sun
Ferroptosis is an iron-dependent form of programmed cell death with the potential to reverse traditional cancer therapy resistance. The combination of ferroptosis with chemotherapy, photodynamic therapy and X-ray therapy has demonstrated remarkably improved therapeutic efficiency. Radiopharmaceutical therapy (RPT) is an emerging approach that achieves precise radiation to diseased tissues via radionuclide delivery. However, insufficient accumulation and retention of therapeutic radiopharmaceuticals in tumor region as well as cancer radioresistance impact treatment efficacy. Here, a nanoassembly of renal clearable ultrasmall iron nanoparticles (USINPs) and 131 I-aPD-L1 is prepared via the affinity of fluorophenylboronic acid modified on the USINPs with 131 I-aPD-L1. The 150 nm USINAs( 131 I-aPD-L1) nanoassembly is stable in blood circulation, effectively targets to the tumor and disassembles in the presence of ATP in the tumor microenvironment. Both in vitro and in vivo experiments prove that USINPs-induced ferroptosis boosted the tumor radiosensitization to 131 I while 131 I-mediated RPT further enhanced ferroptosis. Meanwhile, the immunogenic cell death caused by RPT and ferroptosis combined with PD-L1 immune checkpoint blockade therapy exhibits a strong antitumor immunity. This study provides a novel way to improve the tumor accumulation of ferroptosis inducer and radiopharmaceuticals, insights into the interaction between RPT and ferroptosis and an effective SPECT-guided ferroptosis-enhanced radio-immunotherapy.
研究领域:
纳米技术
·
放射学
·
肿瘤学
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免疫治疗
·
药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
·
2020
·
IF 2.751
Xiang Zhou,Yiqiang Ye,Shasha Liu,Wubin Shao,Liwei Liu,Song Yang,Zhibing Wu
Plant viral diseases, known as “plant cancer”, with high contagiosity can substantially reduce crop quality and yield. To identify potential anti- tobacco mosaic virus (TMV) agents with different mechanisms, a series of novel α-aminophosphonate derivatives containing a chalcone moiety were designed and synthesized. Bioassay results revealed that some target compounds exhibited improved curative activity against TMV in vivo, and the EC 50 value of compound B 3 was 356.7 mg L −1 . The activities of the defensive enzymes POD and CAT from tobacco leaves treated with B 3 and B 17 showed that these target compounds could improve the photosynthetic ability of the leaves and activate plant host resistance against TMV infection. The binding constant between B 3 and TMV Coat Protein (CP) (2.51 × 10 8 M −1 ), calculated by the fluorescence titration experiment and docking results, revealed that B 3 has a strong interaction with TMV CP. Further docking analysis revealed that B 3 was embedded between two layers of the TMV CP, which was consistent with the 2:1 binding mode of TMV CP and B 3 determined by the binding affinity experiment. The TEM morphological study of TMV treated with B 3 and B 17 indicated that this series of target compounds may trigger the disassembly of TMV by interacting directly with TMV CP. This study provides new insight for the discovery of antiviral compounds with two different mechanisms of action.
研究领域:
植物病毒学
·
有机化学
·
植物病理学
·
分子生物学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）