MACROMOLECULAR RAPID COMMUNICATIONS
·
2015
·Vol. 36
·期 6
·533-537
·
IF 4.941
Hao Meng,Jing Zheng,Xiufang Wen,Zhiqi Cai,Jiawei Zhang,Tao Chen
A simple strategy is provided to construct a novel pH- and sugar-induced shape memory hydrogel based on dynamic phenylboronic acid (PBA)–diol interactions formed by PBA-modified sodium alginate (Alg-PBA) and poly(vinyl alcohol) (PVA). The dynamic PBA–diol ester bonds serve as temporary cross-links and stabilize the deformed shape of the hydrogel. The disassociation of the PBA–diol ester bonds is explored in acidic conditions and aqueous solutions of glucose and fructose, which endow the hydrogel with shape memory performances.
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
DALTON TRANSACTIONS
·
2020
·Vol. 49
·期 8
·2437-2443
·
IF 4.174
Chun-Xin Jin,Yu Wang,Qiu-Shan Gao,Dan-Yang Yao,Si-Hong Wang,Donghao Li,Hai-Bo Shang
Exploring new zeolitic imidazolate frameworks (ZIFs) with specific topologies and pore structures is important for extending applications and improving performances. In this work, a new farfalle-shaped ZIF with an ordered hierarchical structure (named ZIF-F) was easily built with zinc acetate and 2-methylimidazole (MeIm) in an aqueous system at room temperature. The synthesis mechanism of ZIF-F is a dual-induction interaction of a solvent and zinc source based on the synthesis protocol of ZIF-8. The prepared ZIF-F is a 3–5 μm dispersible particle constructed from numerous nanoplates with the same building units as ZIF-8. ZIF-F has a rich 4 nm inter-particle spacing with a 0.1074 cm3 g−1 total pore volume and exhibits high thermo- and solvent stability. It is worth noting that crystal transformation could occur from ZIF-F to ZIF-8 in methanol via the dissolution-recrystallization route. Regarding the adsorption of Congo red (CR), ZIF-F exhibits better adsorption capacity (182.82 mg g−1) than ZIF-8 (149.25 mg g−1) with 6 times higher adsorption rate than that of ZIF-8 because of the positive effect of its larger pore size and hierarchical structure.
研究领域:
材料科学
·
化学工程
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DOI
PubMed
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2022
·Vol. 29
·期 4
·1-9
·
IF 3.061
Zhang Andong,Hao Jingyi,Hou Sen,Shi Ge,He Yanjie,Cui Zhe,Liu Minying,Qiao Xiaoguang,Fu Peng,Pang Xinchang
Aggregation-induced emission (AIE) has already been applied for in-situ monitoring living radical polymerization process. Here we utilized functionalized monomer TPEE as fluoresce probes for the in-situ monitoring of photo-induced RAFT-PISA process. Hydrophilic POEGA macro chain transfer agent (Macro-CTA) was first prepared with light sensitive CTA 4-Cyanopentanoic acid dithiobenzoate, and (2-(4-vinylphenyl)ethene-1,1,2-triyl)tribenzene (TPEE) was copolymerized with styrene to form the hydrophobic block under UV irradiation. The growth of hydrophobic block induced the self-assembly of polymer chains and the emission signal could be observed by naked eyes afterwards. The PL intensity increased with the increase of particle size, as well as the monomer conversion and molecular weight, owing to the enhancement of AIE monomer in the self-assembly latex particles. This no-invasive and facile approach to in-situ visualization and continuously monitoring of the photo-induced RAFT-PISA process might be helpful for both scientific research and commercial application.
研究领域:
高分子化学
·
材料科学
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DOI
高影响因子
MOLECULAR CELL
·
2024
·
IF 14.5
Xiaoding Ma,Jianli Yin,Longliang Qiao,Hang Wan,Xingwan Liu,Yang Zhou,Jiali Wu,Lingxue Niu,Min Wu,Xinyi Wang,Haifeng Ye
Myriad physiological and pathogenic processes are governed by protein levels and modifications. Controlled protein activity perturbation is essential to studying protein function in cells and animals. Based on Trim-Away technology, we screened for truncation variants of E3 ubiquitinase Trim21 with elevated efficiency (ΔTrim21) and developed multiple ΔTrim21-based targeted protein-degradation systems (ΔTrim-TPD) that can be transfected into host cells. Three ΔTrim-TPD variants are developed to enable chemical and light-triggered programmable activation of TPD in cells and animals. Specifically, we used ΔTrim-TPD for (1) red-light-triggered inhibition of HSV-1 virus proliferation by degrading the packaging protein gD, (2) for chemical-triggered control of the activity of Cas9/dCas9 protein for gene editing, and (3) for blue-light-triggered degradation of two tumor-associated proteins for spatiotemporal inhibition of melanoma tumor growth in mice. Our study demonstrates that multiple ΔTrim21-based controllable TPD systems provide powerful tools for basic biology research and highlight their potential biomedical applications.
研究领域:
分子生物学
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细胞生物学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Turong Shi,Jiachun Feng,Beibei Tang
Amphiphilic block copolymers are widely used as additives in ultrafiltration membranes preparation by nonsolvent-induced phase separation. During membrane-forming process, an increase in coagulation bath temperature (CBT) will accelerate the kinetics of phase inversion and also promote the micellization of amphiphilic block copolymers. Herein, polyethylene oxide-polypropylene oxide-polyethylene oxide, marketed as Pluronic, is utilized as an additive for preparing asymmetric ultrafiltration membranes. Influence of temperature-induced micelle transition behavior of Pluronic on membrane formation and performance is investigated in detail. It is found that when the CBT increases, temperature-induced micelle transition of Pluronic will lead to a dual effect: (1) The decrease in Pluronic diffusion rate results in a reduced diffusion of the solvent interacting with it, thereby slowing down the precipitation kinetics during phase inversion. (2) The decrease in particle size of Pluronic micelles brings about a reduction in the region left by Pluronic micelles extracted from the casting solution, thus decreasing the membrane pore size. The intrinsic characters of Pluronic, including molecular weight, hydrophilic and hydrophobic block ratio and concentration, determine the dual effect of micelle transition. This work provides an in-depth understanding and practical guidance for the preparation of asymmetric membranes with amphiphilic block copolymers as additive systems.
研究领域:
材料科学
·
膜技术
·
高分子化学
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产品关联
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2015
·
IF 2.495
Chao Xu,Yong Chen,Heng-Yi Zhang,Yu Liu
A crown ether-based supramolecular gel with a three-dimensional network structure was successfully constructed via a hierarchical induced assembly strategy and characterized by UV/vis NMR, viscometry and DLS. Therein, the coordination linkage of bis(terpyridyl)dibenzo-24-crown-8 1 with Zn 2+ produces the 1 /Zn 2+ supramolecular polymer as the primary assembly. Then, the anthryl-dibenzylammonium guest 2 was grafted to the 1 /Zn 2+ supramolecular polymer via the non-covalent association of dibenzylammonium moieties on guests with the dibenzo-24-crown-8 rings on supramolecular polymer. Furthermore, the supramolecular polymer with anthryl grafts underwent a photo-induced secondary assembly to produce the supramolecular gel, which could be reversibly disassembled by a thermo-induced dissociation of anthracene dimers. These photo/thermo-induced hierarchical assembly/disassembly behaviors will provide a potential way to construct degradable hierarchical supramolecular assemblies employing environment-friendly external stimuli, such as light and heat, as controlling method.
研究领域:
化学
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材料科学
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产品关联
DOI
高影响因子
ADVANCED MATERIALS
·
2021
·Vol. 33
·期 49
·2104872
·
IF 30.849
Xiaokai Xu,Luoqi Mo,Yadong Li,Xiaoqin Pan,Guangqi Hu,Bingfu Lei,Xuejie Zhang,Mingtao Zheng,Jianle Zhuang,Yingliang Liu,Chaofan Hu
As one of the most promising fluorescent nanomaterials, the fluorescence of carbon dots (CDs) in solution is extensively studied. Nevertheless, the synthesis of multicolor solid-state fluorescence (SSF) CDs is rarely reported. Herein, CDs with multicolor aggregation-induced emission are prepared using amine molecules, all of them exhibiting dual fluorescence emission at 480 nm (Em-1) and 580–620 nm (Em-2), which is related to the S S bonds of dithiosalicylic acid and the conjugated structure attached to CO/CN bonds, respectively. As a strong electron-withdrawing group, the increase of CN content makes dual-fluorescent groups on the surface of CDs produce push and pull electrons, which determines intramolecular charge transfer (ICT) between the double emission. With the increase in CN content from 35.6% to 58.4%, the ICT efficiency increases from 8.71% to 45.94%, changing the fluorescence of CDs from green to red. The increase of ICT efficiency causes fluorescence quantum yield enhancement by nearly five times and redshift of the fluorescence peak. Finally, based on the multicolor luminescence properties induced by the aggregation of CDs, pattern encryption and white-LED devices are realized. Based on the fat solubility and strong ultraviolet absorption characteristics of CDs, fingerprint detection and leaf anti-UV hazards are applied.
研究领域:
材料科学
·
光学
·
化学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Qianfen Zhuang,Chao Zeng,Yaxin Mu,Tao Zhang,Guotao Yi,Yong Wang
Developing a rapid, efficient, sensitive and selective nabam sensor is essential due to its potential effect on human toxicity and environmental risk. In the report, a fast, ultrasensitive and highly selective sensor for the detection of nabam—disodium ethylenebis(dithiocarbamate) is developed using lead(II)-triggered photoluminescent aggregated gold nanoclusters (AuPbNCs) as probes. The AuPbNCs are synthesized using chloroauric acid, lead(II) acetate basic, and adenosine as the precursors. Detailed characterizations confirm that during the synthesis process of AuPbNCs, lead(II) precursor not only acts as a coupling agent to induce the aggregation of nanoclusters, but also serves as a dopant into nanoclusters. Relative to the photoluminescent adenosine-stabilized gold nanoclusters (AuNCs), AuPbNCs exhibit emission enhancement behavior, ascribing to the structural rigidification and heavy-atom effect of lead. Nabam induces photoluminescence quenching of AuPbNCs, and the quenching process is predominately attributed to static photoinduced electron transfer. A linear relationship with two segments between the photoluminescence quenching ratio of AuPbNCs and nabam concentrations ranging from 0.05 to 25 nM is established, and the detection limit of 20 pM is achieved on the basis of a signal-to-noise (S/N) ratio of 3. Compared with the AuNCs, the highly photoluminescent AuPbNCs exhibit enhanced sensitivity and selectivity for nabam detection. The interaction study between nabam and AuPbNCs reveals that when the added nabam concentration increases, AuPbNCs undergo a process, from aggregation to disaggregation, and then to reaggregation, due to the complexation between nabam and lead or gold of the AuPbNCs. Moreover, the AuPbNCs-based sensor is successfully tested for the nabam detection in real samples (lake water and wheat) and test papers.
研究领域:
分析化学
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环境科学
·
纳米技术
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DOI
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2018
·Vol. 20
·期 42
·27205-27213
·
IF 3.906
Lu Zhou,Ligang Chen,Guanhua Ren,Zhongjie Zhu,Hongwei Zhao,Huabin Wang,Weili Zhang,Jiaguang Han
We present terahertz time-domain spectroscopy (THz-TDS) to explore the conformational dynamics of thermally induced and photoinduced isomerization of azobenzene. The essence of the method is that isomerization of azobenzene proceeds via large structural changes in the molecule, while the THz response is sensitive to these changes. We experimentally demonstrate that the THz spectra of azobenzene show remarkable variations upon heating and irradiation, and as such quantitatively recorded and identified THz spectroscopy can be used to monitor the isomerization process. Specifically, the measured THz spectra clearly reveal that the rate of thermal-isomerization from cis-to-trans in non-polar solvents is faster than that in polar solvents, and an about 6-fold acceleration of the rate could be achieved when Au NPs were introduced as a catalyst into azobenzenes. Moreover, we provide evidence that the temperature and Au NP catalyst do not have an obvious influence on the photoinduced isomerization of azobenzene. The presented example illustrates the power of the THz-TDS method to open up a novel avenue for exploring molecular dynamics.
研究领域:
化学动力学
·
分子光谱学
·
纳米催化
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产品关联
DOI
PubMed
高影响因子
Frontiers in Bioengineering and Biotechnology
·
2023
·
IF 5.7
Wang Lin,Cheng Wen-Chieh,Xue Zhong-Fei,Rahman Md Mizanur,Xie Yi-Xin,Hu Wenle
Inappropriate irrigation could trigger migration of heavy metals into surrounding environments, causing their accumulation and a serious threat to human central nervous system. Traditional site remediation technologies are criticized because they are time-consuming and featured with high risk of secondary pollution. In the past few years, the microbial-induced carbonate precipitation (MICP) is considered as an alternative to traditional technologies due to its easy maneuverability. The enzyme-induced carbonate precipitate (EICP) has attracted attention because bacterial cultivation is not required prior to catalyzing urea hydrolysis. This study compared the performance of lead (Pb) and copper (Cu) remediation using MICP and EICP respectively. The effect of the degree of urea hydrolysis, mass and species of carbonate precipitation, and chemical and thermodynamic properties of carbonates on the remediation efficiency was investigated. Results indicated that ammonium ion (NH4+) concentration reduced with the increase in lead ion (Pb2+) or copper ion (Cu2+) concentration, and for a given Pb2+ or Cu2+ concentration, it was much higher under MICP than EICP. Further, the remediation efficiency against Cu2+ is approximately zero, which is way below that against Pb2+ (approximately 100%). The Cu2+ toxicity denatured and even inactivated the urease, reducing the degree of urea hydrolysis and the remediation efficiency. Moreover, the reduction in the remediation efficiency against Pb2+ and Cu2+ appeared to be due to the precipitations of cotunnite and atacamite respectively. Their chemical and thermodynamic properties were not as good as calcite, cerussite, phosgenite, and malachite. The findings shed light on the underlying mechanism affecting the remediation efficiency against Pb2+ and Cu2+.
研究领域:
环境科学
·
微生物学
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Xinyu Jiang,Yongliang Ma,Feng Gao,Yali Yu
Tiger nut protein fibrils (TNPFs) were prepared through three pathways: self-assembly (TNPF), Homogeneous nuclei (HN)-induced (HN-TNPF), and Secondary nuclei (SN)-induced (SN-TNPF). Differences in morphology, structure, and formation mechanisms among the three TNPFs were examined. HN and SN, serving as fibrillation seeds, enhanced both fibril production and fibrillation rate. Compared to TNPF, the addition of HN and SN shortening the lag time from 3 (TNPF) to 2.2 (HN-TNPF) and 1.89 h (SN-TNPF), respectively. All three TNPFs exhibited fibril structures, notably, SN-TNPF displayed bifurcations on the trunk. Regarding secondary structure, a transition from α-helix to β-sheet was observed in all samples. The dynamic evolution of tertiary structure demonstrated that fibrillation was driven by non-covalent interactions and disulfide bond. After hydrolysis, the identification of specific peptides by LC-MS/MS and core region prediction using AMYLPRED2 showed 89.29 %, 82.22 %, and 89.74 % of peptide sequences in TNPF, HN-TNPF, and SN-TNPF, respectively, possessed fibril forming potential.
研究领域:
生物化学
·
食品科学
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产品关联
DOI
PubMed
高影响因子
Science China-Chemistry
·
2018
·Vol. 61
·期 10
·1301-1306
·
IF 4.448
Wang Sheng,Wang Fang,Li Chengpeng,Li Teng,Cao Derong,Ma Xiang
A novel multifunctional molecule BTE-CNPH was designed and synthesized by connecting 2-(3′,5′-bis(trifluoromethyl)-biphenyl-4-yl)-2-cyanovinyl group to both side of the bisthienylethene (BTE), which exhibited excellent aggregation-induced emission (AIE) and bistable photochromism. High-contrast (>60) reversible fluorescence switching was achieved in the 1D nanowires, solid of BTE-CNPH and also in a polymethyl methacrylate (PMMA) film loaded with 1% BTE-CNPH under the alternative irradiation by 365 nm and visible light. Interestingly, the nanowire-like assembly morphology of BTE-CNPH in aqueous tetrahydrofuran (THF) solution of specific concentration was observed to translate into amorphous pieces gradually upon prolonged irradiation by the 365 nm, accompanying with photo-tunable AIE emission.
研究领域:
材料化学
·
光化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）