MOLECULAR PHARMACEUTICS
·
2018
·
IF 4.556
Mingliang Pei,Jui-Yu Pai,Pengcheng Du,Peng Liu
Fluorescent hyper-cross-linked β-cyclodextrin-carbon quantum dot (β-CD-CQD) hybrid nanosponges of about 200 nm with excellent biocompatibility and strong bright blue fluorescence excited at 365 nm with a high photoluminescence quantum yield (PLQY) of 38.0% were synthesized for tumor theranostic application by facile condensation polymerization of carbon quantum dots (CQDs) with β-cyclodextrin (β-CD) at a feeding ratio of 1:5. The DOX@β-CD-CQD theranostic nanomedicine, around 300 nm with DOX-loading capacity of 39.5% by loading doxorubicin (DOX) via host–guest complexation, showed a pH responsive controlled release and released DOX in the simulated tumor microenvironment in a sustained release mode, owing to the formation constant in the supramolecular complexation of DOX with the β-CD units in the β-CD-CQD nanosponges. The proposed DOX@β-CD-CQD theranostic nanomedicine could be internalized into HepG2 cells, and the released DOX was accumulated into the cell nuclei, demonstrating an antitumor efficacy more enhanced than that of the free drug.
研究领域:
纳米医学
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生物材料
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肿瘤学
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Liqin Zhou,Kungang Chai,Xingdong Yao,Hongbing Ji
It is highly desirable to design and fabricate porous bio-based adsorbent for efficient and selective recovery of acetophenone (AP) and 1-phenylethanol (PE) from the effluent of propylene oxide and styrene monomer co-production (PO/SM) process. Herein, using cassava starch as the starting material, starch-graft-styrene hypercrosslinked polymers (SSHCPs) were designed and synthesized facilely by starch-graft-styrene copolymerization and subsequent crosslinking via a Friedel-Crafts alkylation route. SSHCP-3 (knitted by 4,4′-bis-(chloromethyl)-1,1′-biphenyl) shows high BET surface area (818 m 2 ·g −1 ), large pore volume, and high thermal stability, making it a highly efficient adsorbent for removal of aromatic pollutants from water. SSHCP-3 showed high uptake for AP (2.82 mmol·g −1 ) and selectivity (4.95) of AP over PE in binary-solute adsorption experiments. Spectral studies and theoretical calculation demonstrated that AP and PE uptake could occur at glucose units and benzene moiety via van der Waals interaction and π-π stacking interactions. SSHCP-3 also showed excellent adsorption efficiency of AP (93.6%) and PE (74.4%) in the wastewater discharged from PO/SM process. These results demonstrated that transforming styrene and starch to bio-based hypercrosslinked polymers provides an environmentally friendly and attractive strategy for recovery of AP and PE in practical application.
研究领域:
环境科学
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材料科学
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化学工程
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Kai Zong,Xiaojun Bao,Kejie Jiang,Mei Zhang,Dongshun Deng
Gaseous ammonia (NH 3 ) pollution is harmful to human health and the environment. Developing adsorbents with excellent performance are in demand for NH 3 capture and separation. In this work, hyper-crosslinked polymer (HCP) with abundant pore and suitable surface property was prepared by one-step cross-linking reaction and applied to support various Li salts. The as-obtained Li salts@ HCPs were systematically characterized and evaluated for NH 3 adsorption at different composition and experimental conditions. The preferred [email protected] displayed reversible and outstanding NH 3 adsorption capacity of 37.33 mmol/g at 25℃ and 1.0 bar. Furthermore, kinetic and thermodynamics analysis revealed that the weak chemisorption of NH 3 on [email protected] was mainly controlled by adsorption equilibrium on the inner surface. The adsorption mechanism was elucidated using spectroscopic analysis and DFT calculations. Present work could provide more understanding of the gas–solid adsorption behavior and offer guidance for designing advanced materials for NH 3 capture and separation.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2024
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IF 7.4
Dong Dong,Shujun Zhang,Weiwei Huo,Ming Zhao,Jun Li,Guohua Dong,Yingnan Zhao,Min Zhu,Zhichun Shi
Antibiotic contamination remains a challenge for wastewater treatment . In this work, a hyper-cross-linked polymer (DHCP-TP 3 ) with a dual nitrogen-rich structure was synthesized by a one-step facile Friedel-Crafts reaction, and a Fe 3 O 4 @DHCP-TP 3 composite was prepared by postmodification with the introduction of magnetic iron oxide nanoparticles (Fe 3 O 4 NPs), which were applied to the adsorption of tetracycline (TC) from aqueous solution. The TC adsorption capacities of the DHCP-TP 3 and Fe 3 O 4 @DHCP-TP 3 composites reached 519.65 and 893.85 mg·g −1 , respectively, and the adsorption processes for both followed the pseudo-second-order kinetic model and the Freundlich isothermal model. Fe 3 O 4 @DHCP-TP 3 can achieve adsorption equilibrium for TC within 200 min, and also exhibits excellent regeneration and magnetic separation capabilities. Complexation, hydrogen bonding, cation exchange and π-π interactions were the main adsorption mechanisms. Moreover, Fe 3 O 4 @DHCP-TP 3 could also adsorb other pollutants, including sulfadiazine (SD), sulfamethoxazole (SMZ), methyl orange (MO), methylene blue (MB), 2,4-dichlorophenol (2,4-DCP), and iodine (I 2 ). The brief synthesis, high adsorption capacity and easy regeneration certified that HCPs were ideal adsorbents for removing pollutants from wastewater.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 8
·1-8
·
IF 5.479
Jiang Dandan,Li Zheng,Jia Qiong
The design and preparation of magnetic cucurbit[6]uril hypercrosslinked
with polymers are described. The materials have a large specific surface, abundant
mesopores and cavities, and display superparamagnetism. They were applied to the
enrichment of ubiquitinated peptides from standard protein digests. Following
desorption with 0.15% TFA, the peptides were quantified by MALDI-TOF MS. The method
has a detection limit of 2 fmol·μL −1 and a mass
ratio selectivity of 1:5000 as shown for ubiquitin and bovine serum albumin. The
materials enable selective capture of ubiquitinated peptides from genuine samples
comprising of oyster mushroom and human serum. This demonstrates their potential for
the analysis of low-level ubiquitin in complex samples.
Schematic presentation for the synthesis of magnetic
cucurbit[6]urils hypercrosslinked polymers
(MagCB[6]-HCPs).
研究领域:
生物化学
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分析化学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2021
·
IF 6.953
Kongyou Wu,Kungang Chai,Liqin Zhou,Zhiliang Duan,Haibo Wu,Zhenghui Huang,Dongli Li,Zhongwei Tan,Fang Shen,Zongwu Wei,Hongbing Ji
Herein, a TEMPO-oxidized cellulose-grafted-polystyrene hypercrosslinked polymer (TOC-PS-HCP) was synthesized facilely by TEMPO oxidation , grafting copolymerization and post crosslinking route. Based on the structural characterization, it was confirmed that TOC-PS-HCP mainly consisted of polystyrene chain on cellulose and rigid crosslinked bridge. Additionally, the as-prepared TOC-PS-HCP displayed appropriate hydrophobicity (water contact angle = 102.44°) and high specific surface area (S BET = 601.20 m 2 ·g ‐ −1 ), which could efficiently recover ethylbenzene and styrene from PO/SM wastewater. The adsorption experiment was conducted to study the recovery performance for ethylbenzene and styrene in the aqueous phase. The results showed that TOC-PS-HCP could recover ethylbenzene and styrene quickly by adsorption process, and maintain a stable recovery rate both in different aqueous conditions and recycle experiments. The adsorption experiment in the simulated wastewater solution showed that TOC-PS-HCP exhibited the greater affinity for ethylbenzene and styrene than other substrates. Furthermore, a possible mechanism for the efficient recovery of ethylbenzene and styrene was suggested on the basis of experimental and theoretical results, which may be associated with van der Waals force and π-π stacking.
研究领域:
材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2024
·
IF 8.1
Zhichun Shi,Haoyuan Tang,Liqiu Sun,Jianjun Wang,Jun Li,Dan Wang,Liying Qi,Liyan Wang,Guohua Dong,Ming Zhao
Designing and preparing of materials for highly efficient and reversible iodine adsorption remains a challenging task. In this study, a series of benzonquanmine-based hypercrosslinked polymers (BHCPs) with nitrogen-rich were designed and synthesized via Friedel-Crafts reaction. The obtained BHCPs showed the high specific surface and high thermal stability. Moreover, the BHCP-3 of BHCPs exhibits excellent iodine capture performance, including ultrahigh iodine vapor adsorption capacity of 619 wt%, the breakthrough iodine experiment of the adsorption capacity reached 2.29 g/g, which is the highest published capacity of HCP adsorbent. And the removal rate of iodine in aqueous solution also reached 92.5 %, and reached 87.4 % the first 10 min, demonstrating rapid adsorption effects. Additionally, the iodine adsorption process of BHCPs conformed to the pseudo-second-order kinetic models, and which were a multi-layer adsorption on non-homogeneous surfaces. Furthermore, the three adsorbents maintained more than 85 % of their iodine capture capacity after five cycles, demonstrating their good recyclability and potential for practical applications.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Zi-hui Ma,Tao Yang,Yan Song,Xiao-dong Tian,Zheng-yang Liu,Xiang-jie Gong,Zhan-jun Liu
Hyper cross-linked polymers (HCPs), as a key precursor of hard carbon (HC) anode materials, stand out because of their capacity for molecular-scale structural design and comparatively straightforward preparation techniques, which are not seen in other porous materials synthesized procedure. A novel synthesis method of HCPs is developed in this paper, which is through the incorporation of functional macromolecules , the structural control and heteroatom doping of the product has been achieved, thus augmenting its electrochemical performance in batteries. In this work, carbonized tetraphenylporphyrin zinc (TPP-Zn) doped HCP-based hard carbon (CTHCP) with stable structure was prepared by Friedel-Crafts reaction and carbonization by using naphthalene and trace TPP-Zn as monomers, dimethoxybenzene (DMB) as crosslinking agent and FeCl 3 as catalyst. The introduction of TPP-Zn, a functional macromolecule with unique two-dimensional structure, realized the pore structure regulation and N doping of the raw carbonized HCP-based hard carbon (CHCP). The results showed that CTHCP had higher mesoporous volume, N content and wider layer spacing than CHCP. In addition, CTHCP anode exhibited excellent Li + /Na + storage performance, initial reversible capacity, rate performance and long cycle life. More amount of N -containing (N-5) active sites and mesoporous content in CTHCP anode was the main reason for the improvement of Na + storage effect. While the increased interlayer spacing had a greater effect on the lithium storage capacity. This study uncovered the design rules of HC anode materials suitable for Li + /Na + batteries and provided a new idea for the preparation of high-performance HC anode materials.
研究领域:
材料科学
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能源化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2024
·
IF 1.5
Yan Huijun,Huo Long,Li Mingxia,Azhati Hayinaer,Bai Jianwei
Uranium extraction from seawater is of great significance for the development of the nuclear industry. However, the adsorption of uranium is limited by selectivity of uranium and recycle performance. In this study, amidoxime-functionalized polymer (BP-AO) was prepared by coupling benzene with phenylacetonitrile to extraction uranium from aqueous solution. Adsorption experiments show that the adsorption progress of BP-AO can reach equilibrium within 5 min and the maximum adsorption capacity is 193.9 mg·g −1 calculated by Langmuir model. The selectivity of BP-AO for U(VI) is excellent and after five adsorption–desorption experiments, the adsorption capacity only decreased about 10%. The adsorption mechanism shows that the sorption is mainly due to the formation of stable chelates between the amidoxime groups and U(VI). These results demonstrate the potential application of the adsorbent for practical utilization.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Chuanhong Wang,Xuefang Chen,Shimiao Yao,Fen Peng,Lian Xiong,Haijun Guo,Hairong Zhang,Xinde Chen
Polymerization confined to the pore was first adapted for the nanoscale structure adjustment of adsorption resin. The self-cross-linked polymer (P-1) formed in the pore of hyper-cross-linked resin (HR) by the Friedel–Crafts reaction of p-dichloroxylene (p-DCX), occupying the macropore of the HR resin and bringing about an external micropore. Compared with the raw HR resin, the volume of the micropore of HR@P-1 in 0.4 < D < 1 nm increased but the volume of the macropore has obviously decreased. After the loading of P-1 in the nanopore of HR, HR@P-1 has better gas adsorption performance. At 298 and 100 KPa, the adsorption capacity of CO2 is almost 30% higher than that of HR, reaching 35.7 cm3/g, due to the increase in the smaller micropore volume. Moreover, HR@P-1 has also been found to be the first C2H6-selective adsorption resin. The uptake of C2H6 is up to 56 cm3/g, and the IAST selectivity of C2H6/CH4 reaches 15.3. HR@P-1 can also separate syngas efficiently at ambient temperature and be regenerated by simple vacuum operation.
研究领域:
材料科学
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化学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2020
·
IF 4.049
Weihua Liu,Juntao Wang,Jiajia Liu,Fangyuan Hou,Qiuhua Wu,Chun Wang,Zhi Wang
Hypercrosslinked polymers (HCPs) have demonstrated effective adsorption capabilities because of their rich porosity and high specific surface area. However, the HCPs prepared with phenylboronic acid based compounds as monomers via Friedel-Crafts alkylation reaction have not been reported yet. Herein, four new HCPs with phenylboronic acid (PBA), 1,4-benzenediboronic acid, 4-hydroxyphenylboronic acid and 4-carboxyphenylboronic acid as the respective monomers were prepared for the first time. Their Brunner-Emmet-Teller surface areas were 909.1 m 2 g −1 , 71.9 m 2 g −1 , 39.8 m 2 g −1 and 29.3 m 2 g −1 , respectively. The prepared HCP with PBA as the monomer (named as PBA-HCP) displayed the best adsorption capability for chlorophenols. Then, it was investigated as a SPE adsorbent for the extraction of some chlorophenols from water and honey-pomelo beverage samples prior to high performance liquid-phase chromatography with diode array detection. The established method had low limits of detection for the analytes in the range from 0.06 to 0.2 ng mL −1 for water samples and from 0.3 to 1.0 ng mL −1 for honey-pomelo beverage samples. The linear response for the analytes was in the range of 0.18–100.0 ng mL −1 for water samples and 0.9–100.0 ng mL −1 for honey-pomelo beverage samples. The method also had a good repeatability with the relative standard deviations less than 7.1% and a fairly good accuracy with the method recoveries falling between 80.0% and 120.0%. The adsorption capacities of the PBA-HCP for 2-chlorophenol, 3-chlorophenol, 2,3-dichlorophenol and 2,4-dichlorophenol were 21.7 mg g −1 , 31.2 mg g −1 , 77.1 mg g −1 and 82.1 mg g −1 , respectively. The PBA-HCP also exhibited excellent extraction capabilities for some other compounds, especially for those that have more hydrogen bonding sites.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Dongze Wang,Gang Chen,Xuemei Li,Qiong Jia
A β -cyclodextrin based hypercrosslinked polymer (Bn-CD-HCP) was prepared using 4,4′-bis(chloromethyl)-1,1′-biphenyl as the crosslinker via a Friedel-Crafts reaction. The Bn-CD-HCP material showed high surface area and thermal stability, making it an efficient adsorbent for albendazole, a benzimidazole carbamate. 8 was determined to be the best pH value for albendazole adsorption and the time necessary to reach equilibrium of adsorption was 30 min. The adsorption process agreed with the pseudo-second-order model and Langmuir isotherm model. A high adsorption capacity of 181.82 mg g −1 was achieved. The negative value of Gibbs free energy change suggested a spontaneous adsorption process. In addition, Bn-CD-HCP could be reused for albendazole adsorption for multiple cycles without significant losing its adsorption amount.
研究领域:
环境科学
·
材料科学
·
药学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）