FOOD CHEMISTRY
·
2023
·
IF 8.8
Shanshan Wang,Tian Lei,Leilei Liu,Zhijian Tan
Hesperidin, also known as vitamin P, is widely studied for its distinctive potential in food and pharmaceutical industries. This work focuses on the research of CO 2 -responsive deep eutectic solvents (DESs) used as recyclable extractants for efficient extraction of hesperidin from Fertile orange peel. Reversible phase transformation of DES solution was achieved by bubbling CO 2 /N 2 . The maximum extraction yield of 22.39 mg/g was obtained for hesperidin under the following conditions: DES-6 (triethanolamine: 4-methoxyphenol = 1:1) used as extractant, water content of 35 wt%, solid–liquid ratio of 1:60 g/mL, extraction temperature of 25 °C, and ultrasonic time of 25 min, which was much higher than that extracted by methanol. Hesperidin of 74.38% was recovered in top phase after CO 2 triggering. Density function theory (DFT) results indicated that hydrogen and π - π bonds were the main factors affecting hesperidin extraction. This study provides a new idea for extracting natural bioactive compounds using recyclable extractants.
研究领域:
食品科学
·
植物化学
·
药物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ULTRASONICS SONOCHEMISTRY
·
2025
·
IF 9.7
Jiarong Su,Peishan Li,Xinrui Tang,Zihao Chen,Qiang Peng,Huilin Li,Qianhua Zhang,Shengjie Lu,Famin Wen,Huaicheng Qin,Yongguang Bi,Juan Guo,Fansheng Kong,Haijie Jin,Canzhao Chen,Huiyan Xu
Plant polyphenols have gained increasing attention due to their abundant and powerful biological activities. However, polyphenols from roots of Ilex asprella (RIAPs) remain largely unexplored, with limited research on their composition and bioactivity, making it necessary to focus on RIAPs. In the present study, single - factor analysis and response surface optimization were performed for the extraction of RIAPs via an ultrasonic bath extraction method. The findings demonstrated that at 50 % ethanol concentration, 30 min of ultrasonic time, and 300 W of ultrasonic power, the maximum extraction content of RIAPs was 30.14 ± 0.41 mg/g. Compound and structural analysis via high-resolution liquid chromatography-mass spectrometry (LC-MS/MS) and a Fourier transform infrared (FT-IR) spectrometer confirmed that polyphenols were the majority of compounds comprising RIAPs, in addition to small amounts of alkaloids and trace amounts of other compounds such as amino acids. Scanning electron microscope (SEM) images revealed that RIAPs exhibited a densely reticulated and fragmented microstructure. In addition, bioactivity experiments demonstrated significant antioxidant, antibacterial, anti-inflammatory, and anti-hyperlipidemic activities of RIAPs, supporting their potential pharmaceutical applications. This study provides an experimental foundation for further pharmacological research and potential drug development of RIAPs.
研究领域:
植物学
·
生物化学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2016
·Vol. 21
·期 1
·97
·
IF 2.465
Chang-Wei Zhang,Cheng-Zhang Wang,Ran Tao
In this study, high performance liquid chromatography (HPLC), ultraviolet (UV), thermagravimetric analyzer (TGA), pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS), and scanning electron microscope (SEM) were used as measurement techniques, contents of chemical composition, pyrolytic products, thermal stability, morphological characterization ofGinkgo bilobaleaves (GBL) acted as the index, and physicochemical properties of GBL after enzymolysis based ultrasound extraction (EBUE) and Soxhlet extraction were studied. The detection results of chemical composition revealed that contents of general flavone, soluble protein, soluble total sugar and protein in the GBL declined significantly after EBUE, and contents of polyprenols and crude fat obviously reduced as well after Soxhlet extraction. Py-GC-MS results indicated that total GC contents of micromolecules with carbon less than 12 from 54.0% before EBUE decline to 8.34% after EBUE. Total GC contents of long-chain fatty acids with carbon less than 20 from 43.0% before EBUE reduced to 27.0% after Soxhlet extraction. Thermal stability results showed that GBL after Soxhlet extraction was easier to decompose than GBL before EBUE. SEM results illustrated that surface structure of GBL was damaged severely after EBUE, compared with GBL before EBUE, while organic solvent extraction had little influence on the morphological characterization of GBL after Soxhlet extraction compared with GBL after EBUE.Keywords:physicochemical properties;Ginkgo bilobaleaves;enzymolysis;ultrasound;Soxhlet extraction
研究领域:
植物化学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL SCIENCES
·
2021
·Vol. 37
·期 12
·1735-1740
·
IF 2.081
Zhao Liangcheng,Wei Li,Hu Yanqiao,Chen Qingzhi,Cheng Wencui,Zhang Jinming,Li Xing,An Ziyi,Meng Jianwei,Liu Huajie
Existing methods can not achieve rapid mass decomposition and multi-element analysis of graphite ore samples. In this study, it is found that molten lithium metaborate can destroy the structure of graphite, causing graphite C to be oxidized and decomposed in an oxygen environment. We have established a method for testing graphite ore samples with lithium metaborate at 950°C with melting–ultrasonic extraction–ICP-AES multi-element (Al, Ca, Fe, K, Mg, Mn, Na, P, Si, and Ti) testing. The verification results of the national first-level reference materials show that the detection limit of this method is low and the accuracy and precision are good. The results of the measured samples show no significant difference between this method and the classical chemical analysis method. This method has the following advantages over the existing ones: simple operation process, faster decomposition and testing, low reagent consumption, reduced possibility of sample contamination, and better results reproducibility.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
STARCH-STARKE
·
2024
·
IF 2.6
Guichun Huang,Zhongxia Guo,Jia'na Tan,Qingrui Xu,Chaoyang Wei
Naematelia aurantialba ( N. aurantialba ) is a fungus rich in polysaccharides with medicinal and edible properties. Polysaccharides are the main active components of N. aurantialba ; however, their biological activities and functional properties have not been widely explored. In this study, the ultrasonic extraction process for N. aurantialba polysaccharides (NAP) is optimized, and the physicochemical, functional, and antioxidant activities of the homogeneous fraction (NAP) are investigated. The optimal extraction conditions are a liquid–solid ratio of 50 mL g −1 , ultrasonic power of 430 W, ultrasonic time of 32 min, resulting in an extraction rate of N. aurantialba polysaccharides of 48.68% ± 0.83%. NAP has a molecular weight of 915 kDa. The monosaccharide composition of NAP is as follows: mannose (59.04% ± 0.12%), xylose (23.89% ± 0.03%), glucuronic acid (14.07% ± 0.24%), galacturonic acid (2.12% ± 0.02%), and glucose (0.76% ± 0.02%). NAP exhibites water and oil retention capacities of 14.62 ± 0.25 g g −1 and 23.73 ± 0.85 g g −1 , respectively. Furthermore, NAP demonstrates favorable moisture absorption and retention properties. The results show that NAP has a significantly stronger antioxidant effect, as demonstrated by its concentration-dependent scavenging of ABTS, DPPH, and hydroxyl radicals.
研究领域:
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
FUEL
·
2024
·
IF 6.7
Zhan-Ku Li,Zheng-Zhi Zhang,Kai Zhang,Hong-Lei Yan,Jing-Chong Yan,Zhi-Ping Lei,Shi-Biao Ren,Zhi-Cai Wang,Shi-Gang Kang,Heng-Fu Shui
The migration behavior of organic/inorganic sulfurs is vital for producing high-quality metallurgical coke via pyrolysis. Herein, Lengquan (LQ) fat coal was separated into extract (LQE) and residue (LQR) via ultrasonic extraction, and migration behavior of extracted and residual sulfur as well as effects of LQE and LQR on sulfur removal from coke were further explored in pyrolysis process. The results indicate that LQE has higher volatiles, hydrogen and oxygen contents, while more ash and organic aromatic matrix were remained in LQR. The predominance of difficultly eliminated organic sulfurs in LQE and higher content of easily pyrolyzable inorganic sulfurs in LQR result in weaker and stronger desulfurization effect in pyrolysis, respectively. Sulfides, pyrites, and sulfates are relatively easy to be removed from coke, while sulfones, thiophenes, and sulfoxides are more thermally stable. In co-pyrolysis of LQ with LQE/LQR, the migration of various sulfurs, particularly thiophenes, from coke was significantly enhanced, and the maximum sulfur removal ratio of ca. 56% was achieved in LQ and LQE co-pyrolytic coke. LQE acts as hydrogen/oxygen radical donor and mass transfer promoter, while LQR serves as assistor for gaseous sulfur release, resulting in synergistic desulfurization in LQ with LQE/LQR co-pyrolysis.
研究领域:
煤炭科学
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材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Catalysts
·
2020
·Vol. 10
·期 3
·306
·
IF 3.52
Chunling Wu,Yang Luo,Kai Zhao,Xiaobing Yu,Xian Zhang,Xuqiang Guo
In this paper, direct coal liquefaction residue was prepared from Shen-dong coal, and the solubility of the residue in five organic solvents was studied. Then, an experimental device was set up to recover molybdenum (Mo) compounds from the direct coal liquefaction residue after extraction, and the influences of sublimation temperature and duration on recycling efficiency were examined. The recycled Mo-based products were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), and a thermal analyzer. The results reveal that the optimum extraction conditions were obtained through ultrasonic extraction with a quinoline solvent and the highest recycling efficiency occurred for sublimation at 900 °C for 30 min. The recycled products are identified to be α-MoO3crystals. Moreover, the α-MoO3crystal is thermally stable before the temperature reaches its melting point.
研究领域:
化学工程
·
材料科学
✓ 已验证
DOI
高影响因子
PROCESS BIOCHEMISTRY
·
2015
·
IF 2.516
Chang-Wei Zhang,Cheng-Zhang Wang,Ran Tao,Chuanjie Fang
Polyprenols are one of the most important lipid components in Ginkgo biloba leaves (GBLs). In this study, an enzymolysis-based ultrasound extraction procedure of GBL polyprenol (GBP) lipids was established, and the antioxidant activities of polyprenols and six kinds of polar fractions separated from GBL lipids via an optimal extraction procedure were studied. The results showed that the optimum conditions were an enzyme quantity of 0.5 g (the mass ratio of cellulase and pectinase was 1:2, and the enzyme activity was 60 U/mg), enzymolysis pH of 4.5, and temperature of ultrasound of 45 °C. Under these conditions, the yield of polyprenols was 0.80% ± 0.22%, which is 69.70% higher than that obtained by direct petroleum ether extraction. In addition, concentration c (content of polyprenols was 91.53%), fraction 3 (content of polyprenols was 43.28%), polyprenols (content of polyprenols >99%), and fraction 3 showed the strongest scavenging effect on DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)), superoxide anion, and hydroxyl radicals with the corresponding IC 50 values of 236.9, 76.84, 80.23, and 113.9 μg/mL. It is inferred that GBL lipids with different concentrations of polyprenols could play different roles in the research and development of cosmetics and functional food.
研究领域:
植物化学
·
药理学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Kai Hua,Jiahao He,Xingtong Li,Congyi Zheng,Lingrui Ji,Qingyan Wu,Xi Chen,Ke Gao,Wei Wei,Liping Lu
Liquid crystal monomers (LCMs) are a class of emerging organic pollutants widely used in liquid crystal displays (LCDs) of various electronic products. LCMs can easily be released from LCDs into indoor environments and may pose potential environmental and health risks. Meanwhile, LCMs exhibit a wide range of saturation vapor pressures (PL) and octanol-air partition coefficients (Koa), which enable their presence in various indoor metrices. However, current research on LCMs within indoor multi-medium contexts remains limited. The development of effective analytical methods could significantly advance related research endeavors. This study developed a method using ultrasonic extraction to extract 70 LCMs from dust, gas, and particle samples, and analyzed them using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GC × GC-TOF MS). The recoveries of 70 LCMs in dust, gas and particle phases ranged from 77.7 % to 116 %, 73.8 %–127 %, and 62.1 %–147 %, respectively. The instrument's detection limits and quantification limits were 0.01–1.10 ng/mL and 0.04–3.67 ng/mL, respectively. This demonstrated that the method exhibited satisfactory accuracy and sensitivity, and was further applied to analyze 70 LCMs in indoor dust, gas, and particle phases. 52 LCMs were detected in all three matrices, with significant differences in the distribution of these LCMs across the multi-medium. This method is suitable for determining LCMs concentrations in dust, gas, and particle phases, facilitating a more comprehensive analysis of the occurrence levels of indoor LCMs, and providing a technical reference for future studies on the partitioning behavior and risk assessment of LCMs in indoor multi-medium environments, thereby enhancing our understanding of their environmental impact.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
CHEMISTRY & BIODIVERSITY
·
2025
·
IF 2.5
Shao-Qian Wang,Hui Yuan,Hao-Qiang Qin,Ming-Yue Peng,Ming-Xiao Cui,Ke-Hai Liu
This research emphasized the extraction and separation of polysaccharides derived from Syzygium jambos (L.) Alston (PSJAP-5), as well as analyses of their structural characteristics and immunomodulatory activities. This study initially employed response surface methodology to determine the extraction conditions of polysaccharides. The average molecular weight of PSJAP-5 was 58 102 Da, and its monosaccharide composition was galactose, arabinose, galacturonic acid, glucuronic acid, and rhamnose (39.84:29.13:21.97:6.02:4.17). In vitro studies showed that PSJAP-5 promoted the proliferation and phagocytosis of macrophages. Meanwhile, PSJAP-5 (25–200 µg/mL) promoted the release of NO and ROS, and increased the levels of IL-6, TNF-α, and IL-1β. After pretreating macrophages with TLR4, NF-κB, and MAPK inhibitors, the immunoenhancing effects of PSJAP-5 on macrophages treated with the inhibitors were decreased. Similarly, PSJAP-5 promoted the phosphorylation of p38 in the MAPK signaling pathway and reduced the phosphorylation of IκBα in the NF-κB signaling pathway in RAW264.7 cells. PSJAP-5 might serve as a potential immunomodulator for the treatment of diseases characterized by impaired immune function. Graphical This study focused on extracting and purifying a polysaccharide (PSJAP-5) from Syzygium jambos (L.) Alston, analyzing its structural properties, and evaluating its immunomodulatory effects.
研究领域:
免疫学
·
天然产物化学
·
药用植物学
·
分子生物学
·
糖生物学
·
中药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Zhengyong Wang,Yuqi Cao,Yingjie Lu,Fang Zhang,Yue Su,Yinlong Guo
Ultrasonic extraction and nebulization in real-time/carbon fiber ionization mass spectrometry (UEN/CFI-MS) was developed to screen the synthetic drugs adulterated into herbal products such as antidiabetic drug , antihypertensive drug, and hypolipidemic drug . Recently, ambient ionization MS techniques have achieved great advance for rapid analysis of sample surface. However, direct analysis of the analytes inside samples remains a challenge due to a lack of effective online sample extraction procedures . Owing to disappointing desorption efficiency, analytes inside the sample suffer from low detecting sensitivity when applying ambient ionization MS techniques. In this study, online ultrasonic extraction combined with carbon fiber ionization was used for real-time extraction, nebulization and detection of the analytes inside samples. The ultrasonic atomizer could produce a high-frequency vibration to realize online extraction and nebulization of sample. Then, the produced sample droplets could be immediately ionized by the carbon fiber ionization mass spectrometry . UEN/CFI-MS has shown great compatibility to solvents and compounds with a wide range of polarity and has few limitations for the shape of sample. UEN/CFI-MS was successfully applied for the rapid screening of synthetic drugs adulterated into herbal products. Among 37 batches of herbal products, 1 batch of Chinese patent medicine and 6 batches of dietary supplements were detected to be adulterated with the synthetic chemicals without labeling.
研究领域:
分析化学
·
药物分析
·
医学检测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2011
·
IF 3.722
Xin Zhou,Xiao Shao,Jian-jun Shu,Ming-ming Liu,Han-lan Liu,Xiong-han Feng,Fan Liu
A novel sol–gel-coated ionic liquid-based ([AMIM][N(SO 2 CF 3 ) 2 ]–OH-TSO) fiber was successfully applied for the determination of phthalate esters (PAEs) in agricultural plastic films by ultrasonic extraction (UE) combined with solid phase microextraction–gas chromatography (SPME–GC) due to its high thermal stability, specific selectivity and extraction efficiency. The extractant for UE and the adsorption time for SPME were optimized to achieve higher extraction efficiency. The desorption temperature and time were also optimized to avoid the carryover effect of previous extraction, and ultimately improve the precision and accuracy of the method. The [AMIM][N(SO 2 CF 3 ) 2 ]–OH-TSO fiber showed comparable, or even higher response to most of the investigated PAEs than the commercial PDMS, PDMS–DVB and PA fibers. The carryover problem, often encountered when using commercial fibers, had been eliminated when desorption was performed at 360 °C for 8 min. The proposed SPME–GC method showed good linearity over three to four orders of magnitude, and low limits of detection ranged from 0.003 to 0.063 μg L −1 . The relative standard deviation values obtained were below 10%, and the recoveries were in the ranges of 90.2–111.4%. Some of the PAEs studied were detected at very high concentration in these agricultural plastic film samples, resulting in a potential risk of crop damage, environmental contamination and human health exposure.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）